Matrix-M™ adjuvation broadens protection induced by seasonal trivalent virosomal influenza vaccine Influenza viruses

Virology Journal

Volumn 12, Issue 1, 2015, Pages

  Cox, Freek ^a   Saeland, Eirikur ^a   Baart, Matthijs ^a   Koldijk, Martin ^a   Tolboom, Jeroen ^a   Dekking, Liesbeth ^a   Koudstaal, Wouter ^a   Lövgren Bengtsson, Karin ^b   Goudsmit, Jaap ^a   Radošević, Katarina ^c  

^a Janssen Research and Development   (Netherlands)

^b NOVAVAX INC   (United States)

^c SANOFI   (France)

Author keywords

Adjuvant; Cross reactive HAI response; Matrix M ; Mice; Protection; Seasonal influenza vaccine

Indexed keywords

IMMUNOLOGICAL ADJUVANT; INFLUENZA VACCINE; VIRUS ANTIBODY; VIRUS LIKE PARTICLE VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMORAL IMMUNITY; INFECTION PREVENTION; INFLUENZA A (H1N1); INFLUENZA A (H3N2); INFLUENZA A VIRUS; INFLUENZA B VIRUS; INFLUENZA VACCINATION; MOUSE; NONHUMAN; SURVIVAL RATE; VIRUS STRAIN; WEIGHT REDUCTION; ANIMAL; BAGG ALBINO MOUSE; BLOOD; BODY WEIGHT; GENETICS; HEMAGGLUTINATION INHIBITION TEST; HETEROLOGOUS IMMUNITY; IMMUNOLOGY; ORTHOMYXOVIRIDAE; ORTHOMYXOVIRIDAE INFECTIONS; PATHOLOGY; SEVERITY OF ILLNESS INDEX;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, VIRAL; BODY WEIGHT; FEMALE; HEMAGGLUTINATION INHIBITION TESTS; IMMUNITY, HETEROLOGOUS; INFLUENZA VACCINES; MICE, INBRED BALB C; ORTHOMYXOVIRIDAE; ORTHOMYXOVIRIDAE INFECTIONS; SEVERITY OF ILLNESS INDEX; VACCINES, VIRUS-LIKE PARTICLE;

EID: 84952875558     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/s12985-015-0435-9     Document Type: Article

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