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Newly sequenced HA1 domain accession numbers: AY660991-AY661211. previously published HA1 domain accession numbers are in the supporting material.
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Single-letter abbreviations for the amino acid residues are as follows: I, Ile; K, Lys; N, Asn; and S, Ser.
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We thank R. van Beek, W. Beyer, T. Bhattacharya, R. Bush, N. Cox, B. Grenfell, J. Gog, H. Gutowitz, A. Hay, R. Hightower, T. Jones, A. Tang, the contributors to the WHO global influenza surveillance network, and the maintainers of the influenza Sequence Database (www.flu.tant.gov). We acknowledge the support of the Santa Fe Institute and the Dutch National Institute of Public Health and the Environment (RIVM). D.J.S. was supported by European Union grant QLRT-2001-01034. A.S.L. was supported by the U.S. Department of Energy, contract W-7405-ENG-36, under the Laboratory-Directed Research and Development program. R.A.M.F. is a fellow of the Royal Dutch Academy of Arts and Sciences.
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