Geissoschizine methyl ether protects oxidative stress-mediated cytotoxicity in neurons through the 'Neuronal Warburg Effect'

Journal of Ethnopharmacology

Volumn 187, Issue , 2016, Pages 249-258

  Sun, Jiahong ^c   Ren, Xuefang ^a   Qi, Wen ^b   Yuan, Dan ^b   Simpkins, James W ^a  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Metabolism; Mitochondria; Neuroprotection; Oxidative stress

Indexed keywords

BUTHIONINE SULFOXIMINE; GEISSOSCHIZINE; GEISSOSCHIZINE METHYL ETHER; GLUTAMIC ACID; GLUTATHIONE; NEUROPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; CARBOLINE DERIVATIVE; ETHER DERIVATIVE;

ANIMAL CELL; ARTICLE; CALCEIN-AM ASSAY; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENERGY METABOLISM; GLYCOLYSIS; MITOCHONDRIAL RESPIRATION; NERVE CELL; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PENTOSE PHOSPHATE CYCLE; RAT; WARBURG EFFECT; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CELL LINE; CELL SURVIVAL; DRUG EFFECTS; METABOLISM; MITOCHONDRION; MOUSE; SPRAGUE DAWLEY RAT;

ANIMALS; CARBOLINES; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; ENERGY METABOLISM; ETHERS; GLUTAMIC ACID; GLUTATHIONE; GLYCOLYSIS; MICE; MITOCHONDRIA; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

EID: 84966457197     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2016.04.034     Document Type: Article

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