Effects of geissoschizine methyl ether, an indole alkaloid in uncaria hook, a constituent of yokukansan, on human recombinant serotonin7 receptor

Cellular and Molecular Neurobiology

Volumn 33, Issue 1, 2013, Pages 129-135

  Ueki, Toshiyuki ^a   Nishi, Akinori ^a   Imamura, Sachiko ^a   Kanno, Hitomi ^a   Mizoguchi, Kazushige ^a   Sekiguchi, Kyoji ^a   Ikarashi, Yasushi ^a   Kase, Yoshio ^a  

^a TSUMURA AND CO   (Japan)

Author keywords

5 HT7 receptor; cAMP; CHO cells; Geissoschizine methyl ether; HEK293 cells

Indexed keywords

3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; CORYNOXEINE; CYCLIC AMP; FORSKOLIN; GEISSOSCHIZINE; HIRSUTEINE; HIRSUTINE; ISOCORYNOXEINE; ISORHYNCHOPHYLLINE; NATURAL PRODUCTS AND THEIR SYNTHETIC DERIVATIVES; PLANT MEDICINAL PRODUCT; RECOMBINANT PROTEIN; RHYNCHOPHYLLINE; SEROTONIN; SEROTONIN 7 RECEPTOR; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CELL STRAIN HEK293; CHO CELL; CONCENTRATION RESPONSE; DRUG BINDING; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; EMBRYO; HUMAN; HUMAN CELL; IC 50; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION;

ANIMALS; BINDING, COMPETITIVE; CHO CELLS; CRICETINAE; CRICETULUS; DRUGS, CHINESE HERBAL; HEK293 CELLS; HUMANS; INDOLE ALKALOIDS; INDOLES; RECEPTORS, SEROTONIN; RECOMBINANT PROTEINS; SEROTONIN ANTAGONISTS; UNCARIA;

CRICETULUS GRISEUS; UNCARIA;

EID: 84871760881     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-012-9878-3     Document Type: Article

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