A potential adjuvant chemotherapeutics, 18β-glycyrrhetinic acid, inhibits renal tubular epithelial cells apoptosis via enhancing BMP-7 epigenetically through targeting HDAC2

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Ma, Taotao ^a,b   Huang, Cheng ^b   Meng, Xiaoming ^b   Li, Xiaofeng ^b   Zhang, Yilong ^b   Ji, Shuai ^a   Li, Jun ^b,c   Ye, Min ^a,c   Liang, Hong ^a,c  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

^c NONE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

18ALPHA-GLYCYRRHETINIC ACID; BMP7 PROTEIN, HUMAN; CISPLATIN; GLYCYRRHETINIC ACID; HDAC2 PROTEIN, HUMAN; HISTONE DEACETYLASE 2; OSTEOGENIC PROTEIN 1;

ACUTE KIDNEY FAILURE; ADJUVANT CHEMOTHERAPY; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL SURVIVAL; CHEMICALLY INDUCED; CHEMISTRY; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; HUMAN; KIDNEY TUBULE; METABOLISM; MOLECULAR DOCKING; MOUSE;

ACUTE KIDNEY INJURY; ANIMALS; BONE MORPHOGENETIC PROTEIN 7; CELL LINE; CELL SURVIVAL; CHEMOTHERAPY, ADJUVANT; CISPLATIN; DISEASE MODELS, ANIMAL; EPIGENESIS, GENETIC; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; GLYCYRRHETINIC ACID; HISTONE DEACETYLASE 2; HUMANS; KIDNEY TUBULES; MICE; MOLECULAR DOCKING SIMULATION;

EID: 84966412959     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep25396     Document Type: Article

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