Incorporation of a Michael acceptor enhances the antitumor activity of triterpenoic acids

European Journal of Medicinal Chemistry

Volumn 101, Issue , 2015, Pages 391-399

  Heller, Lucie ^a   Schwarz, Stefan ^a   Perl, Vincent ^a   Köwitsch, Alexander ^a   Siewert, Bianka ^a   Csuk, René ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Glycyrrhetinic acid; Oleanolic acid; Platantic acid; Triterpenoic acid; Tumor cells; Ursolic acid

Indexed keywords

ANTINEOPLASTIC AGENT; GLYCYRRHETINIC ACID DERIVATIVE; OLEANOLIC ACID DERIVATIVE; PLATANIC ACID DERIVATIVE; TRITERPENOIC ACID DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG; URSOLIC ACID DERIVATIVE; TRITERPENE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL LINE; CONTROLLED STUDY; DERIVATIZATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; EC50; HUMAN; HUMAN CELL; CELL PROLIFERATION; CHEMISTRY; CONFORMATION; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL CULTURE;

ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MOLECULAR CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; TRITERPENES; TUMOR CELLS, CULTURED;

EID: 84936993133     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2015.07.004     Document Type: Article

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