Oligodendroglial TNFR2 mediates membrane TNF-dependent repair in experimental autoimmune encephalomyelitis by promoting oligodendrocyte differentiation and remyelination

Journal of Neuroscience

Volumn 36, Issue 18, 2016, Pages 5128-5143

  Madsen, Pernille M ^a,b   Motti, Dario ^c   Karmally, Shaffiat ^a   Szymkowski, David E ^d   Lambertsen, Kate Lykke ^b   Bethea, John R ^e   Brambilla, Roberta ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c NATIONWIDE CHILDREN S HOSPITAL   (United States)

^d Xencor Inc   (United States)

^e DREXEL UNIVERSITY   (United States)

Author keywords

Cytokine; Demyelination; Multiple sclerosis; Neurodegeneration; Neuroinflammation; Remyelination

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 1BETA; MICRORNA; MICRORNA 138; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 2; UNCLASSIFIED DRUG;

ADULT; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN SITU HYBRIDIZATION; INFLAMMATION; MALE; MOTOR COORDINATION; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; OLIGODENDROGLIA; OPEN FIELD TEST; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REMYELINIZATION; ROTAROD TEST; TRANSMISSION ELECTRON MICROSCOPY; TUNEL ASSAY; ANIMAL; AXON; CELL DIFFERENTIATION; CELL SURVIVAL; GENE EXPRESSION REGULATION; GENETICS; GLIA; KNOCKOUT MOUSE; METABOLISM; MYELIN SHEATH; NERVE REGENERATION; NEURAL STEM CELL; PATHOLOGY; PSYCHOLOGY;

ANIMALS; AXONS; BEHAVIOR, ANIMAL; CELL DIFFERENTIATION; CELL SURVIVAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GENE EXPRESSION REGULATION; MALE; MICE; MICE, KNOCKOUT; MYELIN SHEATH; NERVE REGENERATION; NEURAL STEM CELLS; NEUROGLIA; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84965068941     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0211-16.2016     Document Type: Article

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