Conformational dynamics and allostery in pyruvate kinase

Journal of Biological Chemistry

Volumn 291, Issue 17, 2016, Pages 9244-9256

  Donovan, Katherine A ^a   Zhu, Shaolong ^b   Liuni, Peter ^b   Peng, Fen ^c   Kessans, Sarah A ^a   Wilson, Derek J ^b   Dobson, Renwick C J ^a,d  

^a UNIVERSITY OF CANTERBURY   (New Zealand)

^b YORK UNIVERSITY   (Canada)

^c UNIVERSITY OF HOUSTON   (United States)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BINS; DEUTERIUM; DIGITAL STORAGE; DYNAMICS; ELECTROSPRAY IONIZATION; ENZYMES; ESCHERICHIA COLI; FRUCTOSE; MASS SPECTROMETRY; MONOMERS; OLIGOMERS; RIGID STRUCTURES; ROTATION;

ACTIVATION MECHANISMS; ALLOSTERIC MECHANISMS; CONFORMATIONAL DYNAMICS; CONFORMATIONAL FLEXIBILITY; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; FRUCTOSE 1 ,6-BISPHOSPHATE; HYDROGEN-DEUTERIUM EXCHANGE; INCREASED FLEXIBILITY;

CONFORMATIONS;

DEUTERIUM; FRUCTOSE 1,6 BISPHOSPHATE; MONOMER; PYRUVATE KINASE; TETRAMER; ESCHERICHIA COLI PROTEIN;

ALLOSTERISM; ALPHA HELIX; ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; BINDING SITE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVE SITE; ESCHERICHIA COLI; GLYCOLYSIS; LIGAND BINDING; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SIZE EXCLUSION CHROMATOGRAPHY; THERMOSTABILITY; CHEMISTRY; DEUTERIUM HYDROGEN EXCHANGE; ENZYMOLOGY; GENETICS; MOLECULAR MODEL; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

ALLOSTERIC REGULATION; DEUTERIUM EXCHANGE MEASUREMENT; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PYRUVATE KINASE;

EID: 84965005994     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.676270     Document Type: Article

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