Triazolylthioacetamide: A Valid Scaffold for the Development of New Delhi Metallo-β-Lactmase-1 (NDM-1) Inhibitors

ACS Medicinal Chemistry Letters

Volumn 7, Issue 4, 2016, Pages 413-417

  Zhai, Le ^a,b   Zhang, Yi Lin ^a   Kang, Joon S ^c   Oelschlaeger, Peter ^d   Xiao, Lin ^a   Nie, Sha Sha ^a   Yang, Ke Wu ^a  

^a NORTHWEST UNIVERSITY   (China)

^b BAOJI UNIVERSITY OF ARTS AND SCIENCES   (China)

^c CALIFORNIA STATE POLYTECHNIC UNIVERSITY   (United States)

^d WESTERN UNIVERSITY OF HEALTH SCIENCES   (United States)

Author keywords

inhibitor; Metallo lactamase; NDM 1; triazolylthioacetamide

Indexed keywords

ANTIBIOTIC AGENT; CEFAZOLIN; METALLO BETA LACTAMASE; THIOACETAMIDE DERIVATIVE; TRIAZOLYLTHIOACETAMIDE DERIVATIVE; UNCLASSIFIED DRUG; ZINC ION;

ARTICLE; DRUG SYNTHESIS; ENZYME ACTIVITY; IC50; INHIBITION CONSTANT; MOLECULAR DOCKING; NONHUMAN; NUCLEOPHILICITY; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; SUBSTRATE CONCENTRATION;

EID: 84965002978     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/acsmedchemlett.5b00495     Document Type: Article

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