Rutin protects rat articular chondrocytes against oxidative stress induced by hydrogen peroxide through SIRT1 activation

Biochemical and Biophysical Research Communications

Volumn 473, Issue 4, 2016, Pages 1301-1308

  Na, Ji Young ^a   Song, Kibbeum ^a   Kim, Sokho ^a   Kwon, Jungkee ^a  

^a Chonbuk National University   (South Korea)

Author keywords

Chondrocytes; Osteoarthritis; Oxidation; Rutin; SIRT1

Indexed keywords

CYCLOOXYGENASE 2; CYTOKINE; GELATINASE A; GELATINASE B; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; RUTOSIDE; SIRTINOL; SIRTUIN 1; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; SIRT1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE DEGENERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; IMMUNOCYTOCHEMISTRY; MALE; NONHUMAN; OSTEOARTHRITIS; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CHONDROCYTE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; JOINT; MAPK SIGNALING; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; CELLS, CULTURED; CHONDROCYTES; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HYDROGEN PEROXIDE; JOINTS; MALE; MAP KINASE SIGNALING SYSTEM; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RUTIN; SIRTUIN 1;

EID: 84964944663     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2016.04.064     Document Type: Article

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