Production of reactive oxygen species by withaferin A causes loss of type collagen expression and COX-2 expression through the PI3K/Akt, p38, and JNK pathways in rabbit articular chondrocytes

Experimental Cell Research

Volumn 319, Issue 18, 2013, Pages 2822-2834

  Yu, Seon Mi ^a   Kim, Song Ja ^a  

^a Kongju National University   (South Korea)

Author keywords

Chondrocytes; Cyclooxygenase 2; Type II collagen

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; ACTIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; COLLAGEN TYPE 2; CYCLOOXYGENASE 2; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN E2; PROTEIN KINASE B; PROTEOGLYCAN; REACTIVE OXYGEN METABOLITE; SYNAPTOPHYSIN; WITHAFERIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ORYCTOLAGUS CUNICULUS; PANAX GINSENG; WITHANIA SOMNIFERA;

EID: 84886234689     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2013.08.026     Document Type: Article

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