메뉴 건너뛰기




Volumn 146, Issue 5, 2015, Pages 375-386

Modal affinities of endplate acetylcholine receptors caused by loop C mutations

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINERGIC RECEPTOR; CHOLINERGIC RECEPTOR STIMULATING AGENT; PROTEIN BINDING;

EID: 84964889371     PISSN: 00221295     EISSN: 15407748     Source Type: Journal    
DOI: 10.1085/jgp.201511503     Document Type: Article
Times cited : (9)

References (39)
  • 1
    • 34548206866 scopus 로고    scopus 로고
    • Molecular dynamics studies of AChBP with nicotine and carbamylcholine: the role of water in the binding pocket
    • Amiri, S., M.S. Sansom, and P.C. Biggin. 2007. Molecular dynamics studies of AChBP with nicotine and carbamylcholine: the role of water in the binding pocket. Protein Eng. Des. Sel. 20:353-359. http://dx.doi.org/10.1093/protein/gzm029
    • (2007) Protein Eng. Des. Sel. , vol.20 , pp. 353-359
    • Amiri, S.1    Sansom, M.S.2    Biggin, P.C.3
  • 2
    • 84855175213 scopus 로고    scopus 로고
    • Thinking in cycles: MWC is a good model for acetylcholine receptor-channels
    • Auerbach, A. 2012. Thinking in cycles: MWC is a good model for acetylcholine receptor-channels. J. Physiol. 590:93-98. http://dx.doi.org/10.1113/jphysiol.2011.214684
    • (2012) J. Physiol. , vol.590 , pp. 93-98
    • Auerbach, A.1
  • 3
    • 0022558275 scopus 로고
    • Heterogeneous kinetic properties of acetylcholine receptor channels in Xenopus myocytes
    • Auerbach, A., and C.J. Lingle. 1986. Heterogeneous kinetic properties of acetylcholine receptor channels in Xenopus myocytes. J. Physiol. 378:119-140. http://dx.doi.org/10.1113/jphysiol.1986.sp016211
    • (1986) J. Physiol. , vol.378 , pp. 119-140
    • Auerbach, A.1    Lingle, C.J.2
  • 4
    • 0037072311 scopus 로고    scopus 로고
    • Cation-pi interactions in ligand recognition by serotonergic (5-HT3A) and nicotinic acetylcholine receptors: the anomalous binding properties of nicotine
    • Beene, D.L., G.S. Brandt, W. Zhong, N.M. Zacharias, H.A. Lester, and D.A. Dougherty. 2002. Cation-pi interactions in ligand recognition by serotonergic (5-HT3A) and nicotinic acetylcholine receptors: the anomalous binding properties of nicotine. Biochemistry. 41:10262-10269. http://dx.doi.org/10.1021/bi020266d
    • (2002) Biochemistry. , vol.41 , pp. 10262-10269
    • Beene, D.L.1    Brandt, G.S.2    Zhong, W.3    Zacharias, N.M.4    Lester, H.A.5    Dougherty, D.A.6
  • 5
    • 0022558277 scopus 로고
    • Quantitative description of three modes of activity of fast chloride channels from rat skeletal muscle
    • Blatz, A.L., and K.L. Magleby. 1986. Quantitative description of three modes of activity of fast chloride channels from rat skeletal muscle. J. Physiol. 378:141-174. http://dx.doi.org/10.1113/jphysiol.1986.sp016212
    • (1986) J. Physiol. , vol.378 , pp. 141-174
    • Blatz, A.L.1    Magleby, K.L.2
  • 6
    • 84873343341 scopus 로고    scopus 로고
    • Energy for wild-type acetylcholine receptor channel gating from different choline derivatives
    • Bruhova, I., T. Gregg, and A. Auerbach. 2013. Energy for wild-type acetylcholine receptor channel gating from different choline derivatives. Biophys. J. 104:565-574. http://dx.doi.org/10.1016/j.bpj.2012.11.3833
    • (2013) Biophys. J. , vol.104 , pp. 565-574
    • Bruhova, I.1    Gregg, T.2    Auerbach, A.3
  • 8
    • 0036623799 scopus 로고    scopus 로고
    • Desensitization of diliganded mouse muscle nicotinic acetylcholine receptor channels
    • Elenes, S., and A. Auerbach. 2002. Desensitization of diliganded mouse muscle nicotinic acetylcholine receptor channels. J. Physiol. 541:367-383. http://dx.doi.org/10.1113/jphysiol.2001.016022
    • (2002) J. Physiol. , vol.541 , pp. 367-383
    • Elenes, S.1    Auerbach, A.2
  • 9
    • 0037544107 scopus 로고    scopus 로고
    • An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors
    • Grutter, T., L. Prado de Carvalho, N. Le Novère, P.J. Corringer, S. Edelstein, and J.P. Changeux. 2003. An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors. EMBO J. 22:1990-2003. http://dx.doi.org/10.1093/emboj/cdg197
    • (2003) EMBO J. , vol.22 , pp. 1990-2003
    • Grutter, T.1    Prado de Carvalho, L.2    Le Novère, N.3    Corringer, P.J.4    Edelstein, S.5    Changeux, J.P.6
  • 10
    • 84877133114 scopus 로고    scopus 로고
    • Function of interfacial prolines at the transmitter-binding sites of the neuromuscular acetylcholine receptor
    • Gupta, S., P. Purohit, and A. Auerbach. 2013. Function of interfacial prolines at the transmitter-binding sites of the neuromuscular acetylcholine receptor. J. Biol. Chem. 288:12667-12679. http://dx.doi.org/10.1074/jbc.M112.443911
    • (2013) J. Biol. Chem. , vol.288 , pp. 12667-12679
    • Gupta, S.1    Purohit, P.2    Auerbach, A.3
  • 11
    • 85042897508 scopus 로고    scopus 로고
    • The kinetic properties of the human glycine receptor in response to different agonists
    • Hurdiss, E.J., T. Greiner, R. Yu, P.C. Biggin, and L.G. Sivilotti. 2015. The kinetic properties of the human glycine receptor in response to different agonists. Biophys. J. 108:432a. http://dx.doi.org/10.1016/j.bpj.2014.11.2360
    • (2015) Biophys. J. , vol.108
    • Hurdiss, E.J.1    Greiner, T.2    Yu, R.3    Biggin, P.C.4    Sivilotti, L.G.5
  • 12
    • 36549079005 scopus 로고    scopus 로고
    • Mode switching is the major mechanism of ligand regulation of InsP3 receptor calcium release channels
    • Ionescu, L., C. White, K.H. Cheung, J. Shuai, I. Parker, J.E. Pearson, J.K. Foskett, and D.O.D. Mak. 2007. Mode switching is the major mechanism of ligand regulation of InsP3 receptor calcium release channels. J. Gen. Physiol. 130:631-645. http://dx.doi.org/10.1085/jgp.200709859
    • (2007) J. Gen. Physiol. , vol.130 , pp. 631-645
    • Ionescu, L.1    White, C.2    Cheung, K.H.3    Shuai, J.4    Parker, I.5    Pearson, J.E.6    Foskett, J.K.7    Mak, D.O.D.8
  • 13
    • 0022628717 scopus 로고
    • Kinetics of unliganded acetylcholine receptor channel gating
    • Jackson, M.B. 1986. Kinetics of unliganded acetylcholine receptor channel gating. Biophys. J. 49:663-672. http://dx.doi.org/10.1016/S0006-3495(86)83693-1
    • (1986) Biophys. J. , vol.49 , pp. 663-672
    • Jackson, M.B.1
  • 14
    • 84864009008 scopus 로고    scopus 로고
    • An integrated catch-and-hold mechanism activates nicotinic acetylcholine receptors
    • Jadey, S., and A. Auerbach. 2012. An integrated catch-and-hold mechanism activates nicotinic acetylcholine receptors. J. Gen. Physiol. 140:17-28. http://dx.doi.org/10.1085/jgp.201210801
    • (2012) J. Gen. Physiol. , vol.140 , pp. 17-28
    • Jadey, S.1    Auerbach, A.2
  • 15
    • 79951824109 scopus 로고    scopus 로고
    • Design and control of acetylcholine receptor conformational change
    • Jadey, S.V., P. Purohit, I. Bruhova, T.M. Gregg, and A. Auerbach. 2011. Design and control of acetylcholine receptor conformational change. Proc. Natl. Acad. Sci. USA. 108:4328-4333. http://dx.doi.org/10.1073/pnas.1016617108
    • (2011) Proc. Natl. Acad. Sci. USA. , vol.108 , pp. 4328-4333
    • Jadey, S.V.1    Purohit, P.2    Bruhova, I.3    Gregg, T.M.4    Auerbach, A.5
  • 16
    • 0029811223 scopus 로고    scopus 로고
    • Dose-response relations for unnatural amino acids at the agonist binding site of the nicotinic acetylcholine receptor: tests with novel side chains and with several agonists
    • Kearney, P.C., M.W. Nowak, W. Zhong, S.K. Silverman, H.A. Lester, and D.A. Dougherty. 1996. Dose-response relations for unnatural amino acids at the agonist binding site of the nicotinic acetylcholine receptor: tests with novel side chains and with several agonists. Mol. Pharmacol. 50:1401-1412.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 1401-1412
    • Kearney, P.C.1    Nowak, M.W.2    Zhong, W.3    Silverman, S.K.4    Lester, H.A.5    Dougherty, D.A.6
  • 17
    • 33645326499 scopus 로고    scopus 로고
    • Modes and models of GABA(A) receptor gating
    • Lema, G.M., and A. Auerbach. 2006. Modes and models of GABA(A) receptor gating. J. Physiol. 572:183-200. http://dx.doi.org/10.1113/jphysiol.2005.099093
    • (2006) J. Physiol. , vol.572 , pp. 183-200
    • Lema, G.M.1    Auerbach, A.2
  • 18
    • 1942468735 scopus 로고    scopus 로고
    • Modal gating of NMDA receptors
    • Magleby, K.L. 2004. Modal gating of NMDA receptors. Trends Neurosci. 27:231-233. http://dx.doi.org/10.1016/j.tins.2004.03.001
    • (2004) Trends Neurosci. , vol.27 , pp. 231-233
    • Magleby, K.L.1
  • 19
    • 0023734971 scopus 로고
    • Kinetic states and modes of single large-conductance calcium-activated potassium channels in cultured rat skeletal muscle
    • McManus, O.B., and K.L. Magleby. 1988. Kinetic states and modes of single large-conductance calcium-activated potassium channels in cultured rat skeletal muscle. J. Physiol. 402:79-120. http://dx.doi.org/10.1113/jphysiol.1988.sp017195
    • (1988) J. Physiol. , vol.402 , pp. 79-120
    • McManus, O.B.1    Magleby, K.L.2
  • 20
    • 0027325659 scopus 로고
    • Modal shifts in acetylcholine receptor channel gating confer subunit-dependent desensitization
    • Naranjo, D., and P. Brehm. 1993. Modal shifts in acetylcholine receptor channel gating confer subunit-dependent desensitization. Science. 260:1811-1814. http://dx.doi.org/10.1126/science.8511590
    • (1993) Science. , vol.260 , pp. 1811-1814
    • Naranjo, D.1    Brehm, P.2
  • 21
    • 84861145025 scopus 로고    scopus 로고
    • The intrinsic energy of the gating isomerization of a neuromuscular acetylcholine receptor channel
    • Nayak, T.K., P.G. Purohit, and A. Auerbach. 2012. The intrinsic energy of the gating isomerization of a neuromuscular acetylcholine receptor channel. J. Gen. Physiol. 139:349-358. http://dx.doi.org/10.1085/jgp.201110752
    • (2012) J. Gen. Physiol. , vol.139 , pp. 349-358
    • Nayak, T.K.1    Purohit, P.G.2    Auerbach, A.3
  • 22
    • 84917690820 scopus 로고    scopus 로고
    • Functional differences between neurotransmitter binding sites of muscle acetylcholine receptors
    • Nayak, T.K., I. Bruhova, S. Chakraborty, S. Gupta, W. Zheng, and A. Auerbach. 2014. Functional differences between neurotransmitter binding sites of muscle acetylcholine receptors. Proc. Natl. Acad. Sci. USA. 111:17660-17665. http://dx.doi.org/10.1073/pnas.1414378111
    • (2014) Proc. Natl. Acad. Sci. USA. , vol.111 , pp. 17660-17665
    • Nayak, T.K.1    Bruhova, I.2    Chakraborty, S.3    Gupta, S.4    Zheng, W.5    Auerbach, A.6
  • 23
    • 84893051703 scopus 로고    scopus 로고
    • Solving ion channel kinetics with the QuB software
    • Nicolai, C., and F. Sachs. 2013. Solving ion channel kinetics with the QuB software. Biophys. Rev. Lett. 08:191-211. http://dx.doi.org/10.1142/S1793048013300053
    • (2013) Biophys. Rev. Lett. , vol.8 , pp. 191-211
    • Nicolai, C.1    Sachs, F.2
  • 24
    • 0023461777 scopus 로고
    • Modal gating behaviour of single sodium channels from the guinea-pig heart
    • Nilius, B. 1987. Modal gating behaviour of single sodium channels from the guinea-pig heart. Biomed. Biochim. Acta. 46:S662-S667.
    • (1987) Biomed. Biochim. Acta. , vol.46 , pp. S662-S667
    • Nilius, B.1
  • 25
    • 84898657848 scopus 로고    scopus 로고
    • Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors
    • Olsen, J.A., T. Balle, M. Gajhede, P.K. Ahring, and J.S. Kastrup. 2014. Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors. PLoS One. 9:e91232. http://dx.doi.org/10.1371/journal.pone.0091232
    • (2014) PLoS One. , vol.9
    • Olsen, J.A.1    Balle, T.2    Gajhede, M.3    Ahring, P.K.4    Kastrup, J.S.5
  • 26
    • 77956608909 scopus 로고    scopus 로고
    • Characterizing singlechannel behavior of GluA3 receptors
    • Poon, K., L.M. Nowak, and R.E. Oswald. 2010. Characterizing singlechannel behavior of GluA3 receptors. Biophys. J. 99:1437-1446. http://dx.doi.org/10.1016/j.bpj.2010.06.058
    • (2010) Biophys. J. , vol.99 , pp. 1437-1446
    • Poon, K.1    Nowak, L.M.2    Oswald, R.E.3
  • 27
    • 0037407919 scopus 로고    scopus 로고
    • Modal gating of NMDA receptors and the shape of their synaptic response
    • Popescu, G., and A. Auerbach. 2003. Modal gating of NMDA receptors and the shape of their synaptic response. Nat. Neurosci. 6:476-483.
    • (2003) Nat. Neurosci. , vol.6 , pp. 476-483
    • Popescu, G.1    Auerbach, A.2
  • 28
    • 77949816724 scopus 로고    scopus 로고
    • Gating modes in AMPA receptors
    • Prieto, M.L., and L.P. Wollmuth. 2010. Gating modes in AMPA receptors. J. Neurosci. 30:4449-4459. http://dx.doi.org/10.1523/JNEUROSCI.5613-09.2010
    • (2010) J. Neurosci. , vol.30 , pp. 4449-4459
    • Prieto, M.L.1    Wollmuth, L.P.2
  • 29
    • 58549118250 scopus 로고    scopus 로고
    • Unliganded gating of acetylcholine receptor channels
    • Purohit, P., and A. Auerbach. 2009. Unliganded gating of acetylcholine receptor channels. Proc. Natl. Acad. Sci. USA. 106:115-120. http://dx.doi.org/10.1073/pnas.0809272106
    • (2009) Proc. Natl. Acad. Sci. USA. , vol.106 , pp. 115-120
    • Purohit, P.1    Auerbach, A.2
  • 30
    • 77950282036 scopus 로고    scopus 로고
    • Energetics of gating at the apoacetylcholine receptor transmitter binding site
    • Purohit, P., and A. Auerbach. 2010. Energetics of gating at the apoacetylcholine receptor transmitter binding site. J. Gen. Physiol. 135:321-331. http://dx.doi.org/10.1085/jgp.200910384
    • (2010) J. Gen. Physiol. , vol.135 , pp. 321-331
    • Purohit, P.1    Auerbach, A.2
  • 31
    • 84878637061 scopus 로고    scopus 로고
    • Loop C and the mechanism of acetylcholine receptor-channel gating
    • Purohit, P., and A. Auerbach. 2013. Loop C and the mechanism of acetylcholine receptor-channel gating. J. Gen. Physiol. 141:467-478. http://dx.doi.org/10.1085/jgp.201210946
    • (2013) J. Gen. Physiol. , vol.141 , pp. 467-478
    • Purohit, P.1    Auerbach, A.2
  • 32
    • 84862162118 scopus 로고    scopus 로고
    • Sources of energy for gating by neurotransmitters in acetylcholine receptor channels
    • Purohit, P., I. Bruhova, and A. Auerbach. 2012. Sources of energy for gating by neurotransmitters in acetylcholine receptor channels. Proc. Natl. Acad. Sci. USA. 109:9384-9389. http://dx.doi.org/10.1073/pnas.1203633109
    • (2012) Proc. Natl. Acad. Sci. USA. , vol.109 , pp. 9384-9389
    • Purohit, P.1    Bruhova, I.2    Auerbach, A.3
  • 33
    • 84890958919 scopus 로고    scopus 로고
    • Functional anatomy of an allosteric protein
    • Purohit, P., S. Gupta, S. Jadey, and A. Auerbach. 2013. Functional anatomy of an allosteric protein. Nat. Commun. 4:2984. http://dx.doi.org/10.1038/ncomms3984
    • (2013) Nat. Commun. , vol.4 , pp. 2984
    • Purohit, P.1    Gupta, S.2    Jadey, S.3    Auerbach, A.4
  • 34
    • 84903974104 scopus 로고    scopus 로고
    • Catchand-hold activation of muscle acetylcholine receptors having transmitter binding site mutations
    • Purohit, P., I. Bruhova, S. Gupta, and A. Auerbach. 2014. Catchand-hold activation of muscle acetylcholine receptors having transmitter binding site mutations. Biophys. J. 107:88-99. http://dx.doi.org/10.1016/j.bpj.2014.04.057
    • (2014) Biophys. J. , vol.107 , pp. 88-99
    • Purohit, P.1    Bruhova, I.2    Gupta, S.3    Auerbach, A.4
  • 35
    • 0019215162 scopus 로고
    • Single acetylcholineactivated channels show burst-kinetics in presence of desensitizing concentrations of agonist
    • Sakmann, B., J. Patlak, and E. Neher. 1980. Single acetylcholineactivated channels show burst-kinetics in presence of desensitizing concentrations of agonist. Nature. 286:71-73. http://dx.doi.org/10.1038/286071a0
    • (1980) Nature. , vol.286 , pp. 71-73
    • Sakmann, B.1    Patlak, J.2    Neher, E.3
  • 36
    • 0032535779 scopus 로고    scopus 로고
    • Mode switching characterizes the activity of large conductance potassium channels recorded from rat cortical fused nerve terminals
    • Smith, M.A., and M.L. Ashford. 1998. Mode switching characterizes the activity of large conductance potassium channels recorded from rat cortical fused nerve terminals. J. Physiol. 513:733-747. http://dx.doi.org/10.1111/j.1469-7793.1998.733ba.x
    • (1998) J. Physiol. , vol.513 , pp. 733-747
    • Smith, M.A.1    Ashford, M.L.2
  • 37
    • 22244438519 scopus 로고    scopus 로고
    • Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism
    • Taly, A., M. Delarue, T. Grutter, M. Nilges, N. Le Novère, P.-J. Corringer, and J.-P. Changeux. 2005. Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism. Biophys. J. 88:3954-3965. http://dx.doi.org/10.1529/biophysj.104.050229
    • (2005) Biophys. J. , vol.88 , pp. 3954-3965
    • Taly, A.1    Delarue, M.2    Grutter, T.3    Nilges, M.4    Le Novère, N.5    Corringer, P.-J.6    Changeux, J.-P.7
  • 38
    • 56749160114 scopus 로고    scopus 로고
    • Distinct gating modes determine the biphasic relaxation of NMDA receptor currents
    • Zhang, W., J.R. Howe, and G.K. Popescu. 2008. Distinct gating modes determine the biphasic relaxation of NMDA receptor currents. Nat. Neurosci. 11:1373-1375. http://dx.doi.org/10.1038/nn.2214
    • (2008) Nat. Neurosci. , vol.11 , pp. 1373-1375
    • Zhang, W.1    Howe, J.R.2    Popescu, G.K.3
  • 39
    • 0032514762 scopus 로고    scopus 로고
    • From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor
    • Zhong, W., J.P. Gallivan, Y. Zhang, L. Li, H.A. Lester, and D.A. Dougherty. 1998. From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor. Proc. Natl. Acad. Sci. USA. 95:12088-12093. http://dx.doi.org/10.1073/pnas.95.21.12088
    • (1998) Proc. Natl. Acad. Sci. USA. , vol.95 , pp. 12088-12093
    • Zhong, W.1    Gallivan, J.P.2    Zhang, Y.3    Li, L.4    Lester, H.A.5    Dougherty, D.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.