Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Olsen, Jeppe A ^a,b   Balle, Thomas ^c   Gajhede, Michael ^a   Ahring, Philip K ^c,d   Kastrup, Jette S ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NEUROSEARCH A S   (Denmark)

^c UNIVERSITY OF SYDNEY   (Australia)

^d Aniona   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINE BINDING PROTEIN; ALANINE; BINDING PROTEIN; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA4BETA2; TRYPTOPHAN; UNCLASSIFIED DRUG; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; CARRIER PROTEIN; PROTEIN BINDING; PROTEIN P53;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; HYDROGEN BOND; LIGAND BINDING; LYMNAEA STAGNALIS; MOLECULAR RECOGNITION; NONHUMAN; OOCYTE; PROTEIN CONFORMATION; VOLTAGE CLAMP TECHNIQUE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; EVOKED RESPONSE; GENETICS; METABOLISM; MUTATION;

ACETYLCHOLINE; ANIMALS; BINDING SITES; CARRIER PROTEINS; EVOKED POTENTIALS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MUTATION; NEUROTRANSMITTER AGENTS; OOCYTES; PROTEIN BINDING; RECEPTORS, NICOTINIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84898657848     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091232     Document Type: Article

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