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Volumn 6, Issue , 2016, Pages

Screening of efficient siRNA carriers in a library of surface-engineered dendrimers

Author keywords

[No Author keywords available]

Indexed keywords

DENDRIMER; DRUG CARRIER; PAMAM STARBURST; SMALL INTERFERING RNA;

EID: 84964806673     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep25069     Document Type: Article
Times cited : (43)

References (51)
  • 1
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans
    • Fire, A. et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811 (1998).
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1
  • 2
    • 84939886544 scopus 로고    scopus 로고
    • Oligopeptide complex for targeted non-viral gene delivery to adipocytes
    • Won, Y. W. et al. Oligopeptide complex for targeted non-viral gene delivery to adipocytes. Nat. Mater. 13, 1157-1164 (2014).
    • (2014) Nat. Mater , vol.13 , pp. 1157-1164
    • Won, Y.W.1
  • 3
    • 84925516251 scopus 로고    scopus 로고
    • Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy
    • Liang, C. et al. Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy. Nat. Med. 21, 288-294 (2015).
    • (2015) Nat. Med , vol.21 , pp. 288-294
    • Liang, C.1
  • 4
    • 84901357792 scopus 로고    scopus 로고
    • Nanoparticle-formulated sirna targeting integrins inhibits hepatocellular carcinoma progression in mice
    • Bogorad, R. L. et al. Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice. Nat. Commun. 5, 3869 (2014).
    • (2014) Nat. Commun , vol.5 , pp. 3869
    • Bogorad, R.L.1
  • 5
    • 84906706945 scopus 로고    scopus 로고
    • Small RNA combination therapy for lung cancer
    • Xue, W. et al. Small RNA combination therapy for lung cancer. Proc. Natl. Acad. Sci. USA 111, E3553-3561 (2014).
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. E3553-3561
    • Xue, W.1
  • 6
    • 84896512089 scopus 로고    scopus 로고
    • Design and development of effective sirna delivery vehicles
    • Putnam, D. Design and development of effective siRNA delivery vehicles. Proc. Natl. Acad. Sci. USA 111, 3903-3904 (2014).
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 3903-3904
    • Putnam, D.1
  • 8
    • 84865173768 scopus 로고    scopus 로고
    • Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release sirna in cells
    • Geihe, E. I. et al. Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells. Proc. Natl. Acad. Sci. USA 109, 13171-13176 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 13171-13176
    • Geihe, E.I.1
  • 9
    • 84922736573 scopus 로고    scopus 로고
    • Cell type-specific delivery of short interfering rnas by dye-functionalised theranostic nanoparticles
    • Press, A. T. et al. Cell type-specific delivery of short interfering RNAs by dye-functionalised theranostic nanoparticles. Nat. Commun. 5, 5565 (2014).
    • (2014) Nat. Commun , vol.5 , pp. 5565
    • Press, A.T.1
  • 10
    • 84879517970 scopus 로고    scopus 로고
    • Dynamic amphiphile libraries to screen for the "fragrant" delivery of sirna into hela cells and human primary fibroblasts
    • Gehin, C. et al. Dynamic amphiphile libraries to screen for the "fragrant" delivery of siRNA into HeLa cells and human primary fibroblasts. J. Am. Chem. Soc. 135, 9295-9298 (2013).
    • (2013) J. Am. Chem. Soc , vol.135 , pp. 9295-9298
    • Gehin, C.1
  • 11
    • 84880274434 scopus 로고    scopus 로고
    • Efficiency of sirna delivery by lipid nanoparticles is limited by endocytic recycling
    • Sahay, G. et al. Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling. Nat. Biotechnol. 31, 653-658 (2013).
    • (2013) Nat. Biotechnol , vol.31 , pp. 653-658
    • Sahay, G.1
  • 12
    • 84859455253 scopus 로고    scopus 로고
    • Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery
    • Nguyen, D. N. et al. Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery. Proc. Natl. Acad. Sci. USA 109, E797-803 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. E797-803
    • Nguyen, D.N.1
  • 13
    • 84904544984 scopus 로고    scopus 로고
    • Non-viral vectors for gene-based therapy
    • Yin, H. et al. Non-viral vectors for gene-based therapy. Nat. Rev. Genet. 15, 541-555 (2014).
    • (2014) Nat. Rev. Genet , vol.15 , pp. 541-555
    • Yin, H.1
  • 14
    • 84863726330 scopus 로고    scopus 로고
    • Molecularly self-Assembled nucleic acid nanoparticles for targeted in vivo sirna delivery
    • Lee, H. et al. Molecularly self-Assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery. Nat. Nanotechnol. 7, 389-393 (2012).
    • (2012) Nat. Nanotechnol , vol.7 , pp. 389-393
    • Lee, H.1
  • 15
    • 84856480640 scopus 로고    scopus 로고
    • Polyphosphonium polymers for sirna delivery: An efficient and nontoxic alternative to polyammonium carriers
    • Ornelas-Megiatto, C., Wich, P. R. & Frechet, J. M. Polyphosphonium polymers for siRNA delivery: an efficient and nontoxic alternative to polyammonium carriers. J. Am. Chem. Soc. 134, 1902-1905 (2012).
    • (2012) J. Am. Chem. Soc , vol.134 , pp. 1902-1905
    • Ornelas-Megiatto, C.1    Wich, P.R.2    Frechet, J.M.3
  • 16
    • 84866679606 scopus 로고    scopus 로고
    • Conjugation chemistry through acetals toward a dextran-based delivery system for controlled release of sirna
    • Cui, L. et al. Conjugation chemistry through acetals toward a dextran-based delivery system for controlled release of siRNA. J. Am. Chem. Soc. 134, 15840-15848 (2012).
    • (2012) J. Am. Chem. Soc , vol.134 , pp. 15840-15848
    • Cui, L.1
  • 17
    • 79959201542 scopus 로고    scopus 로고
    • Acid-degradable cationic dextran particles for the delivery of sirna therapeutics
    • Cohen, J. L. et al. Acid-degradable cationic dextran particles for the delivery of siRNA therapeutics. Bioconjug. Chem. 22, 1056-1065 (2011).
    • (2011) Bioconjug. Chem , vol.22 , pp. 1056-1065
    • Cohen, J.L.1
  • 18
    • 84878684304 scopus 로고    scopus 로고
    • An influenza virus-inspired polymer system for the timed release of sirna
    • Truong, N. P. et al. An influenza virus-inspired polymer system for the timed release of siRNA. Nat. Commun. 4, 1902 (2013).
    • (2013) Nat. Commun , vol.4 , pp. 1902
    • Truong, N.P.1
  • 19
    • 84906780457 scopus 로고    scopus 로고
    • Bioreducible polymers for therapeutic gene delivery
    • Lee, Y. S. & Kim, S. W. Bioreducible polymers for therapeutic gene delivery. J. Control. Release 190, 424-439 (2014).
    • (2014) J. Control. Release , vol.190 , pp. 424-439
    • Lee, Y.S.1    Kim, S.W.2
  • 20
    • 77958454568 scopus 로고    scopus 로고
    • Cationic nanosystems for the delivery of small interfering ribonucleic acid therapeutics: A focus on toxicogenomics
    • Akhtar, S. Cationic nanosystems for the delivery of small interfering ribonucleic acid therapeutics: a focus on toxicogenomics. Expert. Opin. Drug. Metab. Toxicol. 6, 1347-1362 (2010).
    • (2010) Expert. Opin. Drug. Metab. Toxicol , vol.6 , pp. 1347-1362
    • Akhtar, S.1
  • 21
    • 84919388693 scopus 로고    scopus 로고
    • Adaptive amphiphilic dendrimer-based nanoassemblies as robust and versatile sirna delivery systems
    • Liu, X. et al. Adaptive amphiphilic dendrimer-based nanoassemblies as robust and versatile siRNA delivery systems. Angew. Chem. Int. Ed. 53, 11822-11827 (2014).
    • (2014) Angew. Chem. Int. Ed , vol.53 , pp. 11822-11827
    • Liu, X.1
  • 22
    • 84886930350 scopus 로고    scopus 로고
    • Poly(trehalose): Sugar-coated nanocomplexes promote stabilization and effective polyplex-mediated sirna delivery
    • Sizovs, A. et al. Poly(trehalose): sugar-coated nanocomplexes promote stabilization and effective polyplex-mediated siRNA delivery. J. Am. Chem. Soc. 135, 15417-15424 (2013).
    • (2013) J. Am. Chem. Soc , vol.135 , pp. 15417-15424
    • Sizovs, A.1
  • 23
    • 41449109039 scopus 로고    scopus 로고
    • Breathing life into polycations: Functionalization with ph-responsive endosomolytic peptides and polyethylene glycol enables sirna delivery
    • Meyer, M., Philipp, A., Oskuee, R., Schmidt, C. & Wagner, E. Breathing life into polycations: functionalization with pH-responsive endosomolytic peptides and polyethylene glycol enables siRNA delivery. J. Am. Chem. Soc. 130, 3272-3273 (2008).
    • (2008) J. Am. Chem. Soc , vol.130 , pp. 3272-3273
    • Meyer, M.1    Philipp, A.2    Oskuee, R.3    Schmidt, C.4    Wagner, E.5
  • 24
    • 84886546900 scopus 로고    scopus 로고
    • Single vehicular delivery of sirna and small molecules to control stem cell differentiation
    • Shah, S., Solanki, A., Sasmal, P. K. & Lee, K. B. Single vehicular delivery of siRNA and small molecules to control stem cell differentiation. J. Am. Chem. Soc. 135, 15682-15685 (2013).
    • (2013) J. Am. Chem. Soc , vol.135 , pp. 15682-15685
    • Shah, S.1    Solanki, A.2    Sasmal, P.K.3    Lee, K.B.4
  • 25
    • 84930819390 scopus 로고    scopus 로고
    • Polymers modified with double-tailed fluorous compounds for efficient DNA and sirna delivery
    • He, B., Wang, Y., Shao, N., Chang, H. & Cheng, Y. Polymers modified with double-tailed fluorous compounds for efficient DNA and siRNA delivery. Acta biomaterialia 22, 111-119 (2015).
    • (2015) Acta Biomaterialia , vol.22 , pp. 111-119
    • He, B.1    Wang, Y.2    Shao, N.3    Chang, H.4    Cheng, Y.5
  • 26
    • 84875774121 scopus 로고    scopus 로고
    • Multifunctional dendronized peptide polymer platform for safe and effective sirna delivery
    • Zeng, H., Little, H. C., Tiambeng, T. N., Williams, G. A. & Guan, Z. Multifunctional dendronized peptide polymer platform for safe and effective siRNA delivery. J. Am. Chem. Soc. 135, 4962-4965 (2013).
    • (2013) J. Am. Chem. Soc , vol.135 , pp. 4962-4965
    • Zeng, H.1    Little, H.C.2    Tiambeng, T.N.3    Williams, G.A.4    Guan, Z.5
  • 27
    • 67650489113 scopus 로고    scopus 로고
    • Synthesis and characterization of a carbon nanotube-dendron series for efficient sirna delivery
    • Herrero, M. A. et al. Synthesis and characterization of a carbon nanotube-dendron series for efficient siRNA delivery. J. Am. Chem. Soc. 131, 9843-9848 (2009).
    • (2009) J. Am. Chem. Soc , vol.131 , pp. 9843-9848
    • Herrero, M.A.1
  • 28
    • 84935909642 scopus 로고    scopus 로고
    • Surface-engineered dendrimers in gene delivery
    • Yang, J., Zhang, Q., Chang, H. & Cheng, Y. Surface-Engineered Dendrimers in Gene Delivery. Chem. Rev. 115, 5274-5300 (2015).
    • (2015) Chem. Rev , vol.115 , pp. 5274-5300
    • Yang, J.1    Zhang, Q.2    Chang, H.3    Cheng, Y.4
  • 29
    • 84903643579 scopus 로고    scopus 로고
    • Degradable lipid nanoparticles with predictable in vivo sirna delivery activity
    • Whitehead, K. A. et al. Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity. Nat. Commun. 5, 4277 (2014).
    • (2014) Nat. Commun , vol.5 , pp. 4277
    • Whitehead, K.A.1
  • 30
    • 84896519424 scopus 로고    scopus 로고
    • Lipopeptide nanoparticles for potent and selective sirna delivery in rodents and nonhuman primates
    • Dong, Y. et al. Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates. Proc. Natl. Acad. Sci. USA 111, 3955-3960 (2014).
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 3955-3960
    • Dong, Y.1
  • 31
    • 43049176170 scopus 로고    scopus 로고
    • A combinatorial library of lipid-like materials for delivery of rnai therapeutics
    • Akinc, A. et al. A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nat. Biotechnol. 26, 561-569 (2008).
    • (2008) Nat. Biotechnol , vol.26 , pp. 561-569
    • Akinc, A.1
  • 32
    • 80052010600 scopus 로고    scopus 로고
    • Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery
    • Siegwart, D. J. et al. Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery. Proc. Natl. Acad. Sci. USA 108, 12996-13001 (2011).
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 12996-13001
    • Siegwart, D.J.1
  • 33
    • 84883489625 scopus 로고    scopus 로고
    • Lipid-modified aminoglycoside derivatives for in vivo sirna delivery
    • Zhang, Y. et al. Lipid-modified aminoglycoside derivatives for in vivo siRNA delivery. Adv. Mater. 25, 4641-4645 (2013).
    • (2013) Adv. Mater , vol.25 , pp. 4641-4645
    • Zhang, Y.1
  • 34
    • 84865584957 scopus 로고    scopus 로고
    • In vitro-in vivo translation of lipid nanoparticles for hepatocellular sirna delivery
    • Whitehead, K. A. et al. In vitro-in vivo translation of lipid nanoparticles for hepatocellular siRNA delivery. ACS Nano 6, 6922-6929 (2012).
    • (2012) ACS Nano , vol.6 , pp. 6922-6929
    • Whitehead, K.A.1
  • 35
    • 76649098887 scopus 로고    scopus 로고
    • Lipid-like materials for low-dose, in vivo gene silencing
    • Love, K. T. et al. Lipid-like materials for low-dose, in vivo gene silencing. Proc. Natl. Acad. Sci. USA 107, 1864-1869 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 1864-1869
    • Love, K.T.1
  • 36
    • 76349111051 scopus 로고    scopus 로고
    • Rational design of cationic lipids for sirna delivery
    • Semple, S. C. et al. Rational design of cationic lipids for siRNA delivery. Nat. Biotechnol. 28, 172-176 (2010).
    • (2010) Nat. Biotechnol , vol.28 , pp. 172-176
    • Semple, S.C.1
  • 37
    • 84881408604 scopus 로고    scopus 로고
    • Multiparametric approach for the evaluation of lipid nanoparticles for sirna delivery
    • Alabi, C. A. et al. Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery. Proc. Natl. Acad. Sci. USA 110, 12881-12886 (2013).
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 12881-12886
    • Alabi, C.A.1
  • 38
    • 84905718745 scopus 로고    scopus 로고
    • In vivo endothelial sirna delivery using polymeric nanoparticles with low molecular weight
    • Dahlman, J. E., Barnes, C. & Khan, O. F. In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight. Nat. Nanotechnol. 9, 648-655 (2014).
    • (2014) Nat. Nanotechnol , vol.9 , pp. 648-655
    • Dahlman, J.E.1    Barnes, C.2    Khan, O.F.3
  • 39
    • 84919667820 scopus 로고    scopus 로고
    • Ionizable amphiphilic dendrimer-based nanomaterials with alkyl-chain-substituted amines for tunable sirna delivery to the liver endothelium in vivo
    • Khan, O. F. et al. Ionizable amphiphilic dendrimer-based nanomaterials with alkyl-chain-substituted amines for tunable siRNA delivery to the liver endothelium in vivo. Angew. Chem. Int. Ed. 53, 14397-14401 (2014).
    • (2014) Angew. Chem. Int. Ed , vol.53 , pp. 14397-14401
    • Khan, O.F.1
  • 40
    • 84929180252 scopus 로고    scopus 로고
    • Dendrimer-inspired nanomaterials for the in vivo delivery of sirna to lung vasculature
    • Khan, O. F. et al. Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature. Nano. Lett. 15, 3008-3016 (2015).
    • (2015) Nano. Lett , vol.15 , pp. 3008-3016
    • Khan, O.F.1
  • 41
    • 18444392735 scopus 로고    scopus 로고
    • Birth of a new macromolecular architecture: Dendrimers as quantized building blocks for nanoscale synthetic polymer chemistry
    • Tomalia, D. A. Birth of a new macromolecular architecture: dendrimers as quantized building blocks for nanoscale synthetic polymer chemistry. Prog. Polym. Sci. 30, 294-324 (2005).
    • (2005) Prog. Polym. Sci , vol.30 , pp. 294-324
    • Tomalia, D.A.1
  • 42
    • 28644434579 scopus 로고    scopus 로고
    • Designing dendrimers for biological applications
    • Lee, C. C., MacKay, J. A., Frechet, J. M. & Szoka, F. C. Designing dendrimers for biological applications. Nat. Biotechnol. 23, 1517-1526 (2005).
    • (2005) Nat. Biotechnol , vol.23 , pp. 1517-1526
    • Lee, C.C.1    MacKay, J.A.2    Frechet, J.M.3    Szoka, F.C.4
  • 43
    • 12844258906 scopus 로고    scopus 로고
    • Dendrimers and dendritic polymers in drug delivery
    • Gillies, E. R. & Frechet, J. M. Dendrimers and dendritic polymers in drug delivery. Drug. Discov. Today 10, 35-43 (2005).
    • (2005) Drug. Discov. Today , vol.10 , pp. 35-43
    • Gillies, E.R.1    Frechet, J.M.2
  • 44
    • 84911990896 scopus 로고    scopus 로고
    • Emerging concepts in dendrimer-based nanomedicine: From design principles to clinical applications
    • Kannan, R. M., Nance, E., Kannan, S. & Tomalia, D. A. Emerging concepts in dendrimer-based nanomedicine: from design principles to clinical applications. J. Intern. Med. 276, 579-617 (2014).
    • (2014) J. Intern. Med , vol.276 , pp. 579-617
    • Kannan, R.M.1    Nance, E.2    Kannan, S.3    Tomalia, D.A.4
  • 45
    • 84870251061 scopus 로고    scopus 로고
    • Dendrimers in biomedical applications-reflections on the field
    • Svenson, S. & Tomalia, D. A. Dendrimers in biomedical applications-reflections on the field. Adv. Drug. Deliv. Rev. 64, 102-115 (2012).
    • (2012) Adv. Drug. Deliv. Rev , vol.64 , pp. 102-115
    • Svenson, S.1    Tomalia, D.A.2
  • 46
    • 84887003262 scopus 로고    scopus 로고
    • Balancing cationic and hydrophobic content of pegylated sirna polyplexes enhances endosome escape, stability, blood circulation time, and bioactivity in vivo
    • Nelson, C. E. et al. Balancing Cationic and Hydrophobic Content of PEGylated siRNA Polyplexes Enhances Endosome Escape, Stability, Blood Circulation Time, and Bioactivity in vivo. ACS nano 7, 8870-8880 (2013).
    • (2013) ACS Nano , vol.7 , pp. 8870-8880
    • Nelson, C.E.1
  • 47
    • 77956187410 scopus 로고    scopus 로고
    • Hydrophobic modifications of cationic polymers for gene delivery
    • Liu, Z., Zhang, Z., Zhou, C. & Jiao, Y. Hydrophobic modifications of cationic polymers for gene delivery. Prog. Polym. Sci. 35, 1144-1162 (2010).
    • (2010) Prog. Polym. Sci , vol.35 , pp. 1144-1162
    • Liu, Z.1    Zhang, Z.2    Zhou, C.3    Jiao, Y.4
  • 48
    • 84865066015 scopus 로고    scopus 로고
    • An amphiphilic dendrimer for effective delivery of small interfering RNA and gene silencing in vitro and in vivo
    • Yu, T. et al. An amphiphilic dendrimer for effective delivery of small interfering RNA and gene silencing in vitro and in vivo. Angew. Chem. Int. Ed. 51, 8478-8484 (2012).
    • (2012) Angew. Chem. Int. Ed , vol.51 , pp. 8478-8484
    • Yu, T.1
  • 49
    • 77953239685 scopus 로고    scopus 로고
    • Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells
    • Santos, J. L. et al. Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells. J. Control. Release 144, 55-64 (2010).
    • (2010) J. Control. Release , vol.144 , pp. 55-64
    • Santos, J.L.1
  • 50
    • 84892176171 scopus 로고    scopus 로고
    • A fluorinated dendrimer achieves excellent gene transfection efficacy at extremely low nitrogen to phosphorus ratios
    • Wang, M., Liu, H., Li, L. & Cheng, Y. A fluorinated dendrimer achieves excellent gene transfection efficacy at extremely low nitrogen to phosphorus ratios. Nat. Commun. 5, 3053 (2014).
    • (2014) Nat. Commun , vol.5 , pp. 3053
    • Wang, M.1    Liu, H.2    Li, L.3    Cheng, Y.4
  • 51
    • 84861717563 scopus 로고    scopus 로고
    • Alkane-modified short polyethyleneimine for sirna delivery
    • Schroeder, A. et al. Alkane-modified short polyethyleneimine for siRNA delivery. J. Control. Release 160, 172-176 (2012).
    • (2012) J. Control. Release , vol.160 , pp. 172-176
    • Schroeder, A.1


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