-
1
-
-
34447559636
-
Interfering with disease: A progress report on siRNA-based therapeutics
-
DOI 10.1038/nrd2310, PII NRD2310
-
Fougerolles, A., Vornlocher, H.-P., Maraganore, J., and Lieberman, J. (2007) Interfering with disease: A progress report on siRNA-based therapeutics Nat. Rev. Drug Discovery 6, 443-453 (Pubitemid 47064567)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.6
, pp. 443-453
-
-
De Fougerolles, A.1
Vornlocher, H.-P.2
Maraganore, J.3
Lieberman, J.4
-
2
-
-
33751099034
-
RNAi therapeutics: A potential new class of pharmaceutical drugs
-
DOI 10.1038/nchembio839, PII NCHEMBIO839
-
Bumcrot, D., Manoharan, M., Koteliansky, V., and Sah, D. W. Y. (2006) RNAi therapeutics: A potential new class of pharmaceutical drugs Nat. Chem. Biol. 2, 711-719 (Pubitemid 44764213)
-
(2006)
Nature Chemical Biology
, vol.2
, Issue.12
, pp. 711-719
-
-
Bumcrot, D.1
Manoharan, M.2
Koteliansky, V.3
Sah, D.W.Y.4
-
3
-
-
60149094505
-
RNA interference: From basic research to therapeutic applications
-
Kurreck, J. (2009) RNA interference: From basic research to therapeutic applications Angew. Chem., Int. Ed. 48, 1378-1398
-
(2009)
Angew. Chem., Int. Ed.
, vol.48
, pp. 1378-1398
-
-
Kurreck, J.1
-
4
-
-
0035261255
-
Post-transcriptional gene silencing by double-stranded RNA
-
DOI 10.1038/35052556
-
Hammond, S. M., Caudy, A. A., and Hannon, G. J. (2001) Post-transcriptional gene silencing by double-stranded RNA Nat. Rev. Genet. 2, 110-119 (Pubitemid 33674002)
-
(2001)
Nature Reviews Genetics
, vol.2
, Issue.2
, pp. 110-119
-
-
Hammond, S.M.1
Caudy, A.A.2
Hannon, G.J.3
-
5
-
-
0035795428
-
RNA interference and small interfering RNAs
-
Tuschl, T. (2001) RNA interference and small interfering RNAs ChemBioChem 2, 239-245 (Pubitemid 33722551)
-
(2001)
ChemBioChem
, vol.2
, Issue.4
, pp. 239-245
-
-
Tuschl, T.1
-
6
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
DOI 10.1038/35053110
-
Bernstein, E., Caudy, A. A., Hammond, S. M., and Hannon, G. J. (2001) Role for a bidentate ribonuclease in the initiation step of RNA interference Nature 409, 363-366 (Pubitemid 32151243)
-
(2001)
Nature
, vol.409
, Issue.6818
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
7
-
-
5144225452
-
Biochemical identification of Argonaute 2 as the protein required for RNA-induced silencing complex activity
-
DOI 10.1073/pnas.0405913101
-
Rand, T. A., Ginalski, K., Grishin, N. V., and Wang, X. (2004) Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity Proc. Natl. Acad. Sci. U.S.A. 101, 14385-14389 (Pubitemid 39346758)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.40
, pp. 14385-14389
-
-
Rand, T.A.1
Ginalski, K.2
Grishin, N.V.3
Wang, X.4
-
8
-
-
34447102459
-
Molecular Basis for Target RNA Recognition and Cleavage by Human RISC
-
DOI 10.1016/j.cell.2007.04.037, PII S0092867407005831
-
Ameres, S. L., Martinez, J., and Schroeder, R. (2007) Molecular basis for target RNA recognition and cleavage by human RISC Cell 130, 101-112 (Pubitemid 47031315)
-
(2007)
Cell
, vol.130
, Issue.1
, pp. 101-112
-
-
Ameres, S.L.1
Martinez, J.2
Schroeder, R.3
-
9
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
Hutvágner, G. and Zamore, P. D. (2002) A microRNA in a multiple-turnover RNAi enzyme complex Science 297, 2056-2060
-
(2002)
Science
, vol.297
, pp. 2056-2060
-
-
Hutvágner, G.1
Zamore, P.D.2
-
10
-
-
59349116903
-
Knocking down barriers: Advances in siRNA delivery
-
Whitehead, K. A., Langer, R., and Anderson, D. G. (2009) Knocking down barriers: Advances in siRNA delivery Nat. Rev. Drug Discovery 8, 129-138
-
(2009)
Nat. Rev. Drug Discovery
, vol.8
, pp. 129-138
-
-
Whitehead, K.A.1
Langer, R.2
Anderson, D.G.3
-
11
-
-
77954766405
-
Peptide- and polymer-based delivery of therapeutic RNA
-
Fröhlich, T. and Wagner, E. (2010) Peptide- and polymer-based delivery of therapeutic RNA Soft Matter 6, 226-234
-
(2010)
Soft Matter
, vol.6
, pp. 226-234
-
-
Fröhlich, T.1
Wagner, E.2
-
12
-
-
22144447455
-
Design and development of polymers for gene delivery
-
DOI 10.1038/nrd1775
-
Pack, D. W., Hoffman, A. S., Pun, S., and Stayton, P. S. (2005) Design and development of polymers for gene delivery Nat. Rev. Drug Discovery 4, 581-593 (Pubitemid 40975711)
-
(2005)
Nature Reviews Drug Discovery
, vol.4
, Issue.7
, pp. 581-593
-
-
Pack, D.W.1
Hoffman, A.S.2
Pun, S.3
Stayton, P.S.4
-
13
-
-
0343852892
-
Adeno-associated virus as a gene delivery system
-
DOI 10.1016/S0169-409X(97)00024-0, PII S0169409X97000240
-
During, M. J. (1997) Adeno-associated virus as a gene delivery system Adv. Drug Delivery Rev. 27, 83-94 (Pubitemid 27301399)
-
(1997)
Advanced Drug Delivery Reviews
, vol.27
, Issue.1
, pp. 83-94
-
-
During, M.J.1
-
14
-
-
0030928619
-
Gene therapy - Promises, problems and prospects
-
DOI 10.1038/38410
-
Verma, I. M. and Somia, N. (1997) Gene therapy-Promises, problems, and prospects Nature 389, 239-242 (Pubitemid 27406627)
-
(1997)
Nature
, vol.389
, Issue.6648
, pp. 239-242
-
-
Verma, I.M.1
Somia, N.2
-
15
-
-
50249125921
-
Molecular engineering of viral gene delivery vehicles
-
Schaffer, D. V., Koerber, J. T., and Lim, K. (2008) Molecular engineering of viral gene delivery vehicles Annu. Rev. Biomed. Eng. 10, 169-194
-
(2008)
Annu. Rev. Biomed. Eng.
, vol.10
, pp. 169-194
-
-
Schaffer, D.V.1
Koerber, J.T.2
Lim, K.3
-
16
-
-
64549134676
-
Nonviral vectors for gene delivery
-
Mintzer, M. A. and Simanek, E. E. (2009) Nonviral vectors for gene delivery Chem. Rev. 109, 259-302
-
(2009)
Chem. Rev.
, vol.109
, pp. 259-302
-
-
Mintzer, M.A.1
Simanek, E.E.2
-
17
-
-
0038745599
-
Progress and problems with the use of viral vectors for gene therapy
-
DOI 10.1038/nrg1066
-
Thomas, C. E., Ehrhardt, A., and Kay, M. A. (2003) Progress and problems with the use of viral vectors for gene therapy Nat. Rev. Genet. 4, 346-358 (Pubitemid 36538359)
-
(2003)
Nature Reviews Genetics
, vol.4
, Issue.5
, pp. 346-358
-
-
Thomas, C.E.1
Ehrhardt, A.2
Kay, M.A.3
-
18
-
-
44049083209
-
Immunity to adeno-associated virus vectors in animals and humans: A continued challenge
-
DOI 10.1038/gt.2008.54, PII GT200854, Special Issue: AAV Vectors for Clinical GeneTherapy
-
Zaiss, A. K. and Muruve, D. A. (2008) Immunity to adeno-associated virus vectors in animals and humans: A continued challenge Gene Ther. 15, 808-816 (Pubitemid 351712613)
-
(2008)
Gene Therapy
, vol.15
, Issue.11
, pp. 808-816
-
-
Zaiss, A.K.1
Muruve, D.A.2
-
19
-
-
3142714019
-
Cationic liposome-mediated RNA transfection
-
Malone, R. W., Felgner, P. L., and Verma, I. M. (1989) Cationic liposome-mediated RNA transfection Proc. Natl. Acad. Sci. U.S.A. 86, 6077-6081 (Pubitemid 19210605)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.16
, pp. 6077-6081
-
-
Malone, R.W.1
Felgner, P.L.2
Verma, I.M.3
-
20
-
-
33646185371
-
RNAi-mediated gene silencing in non-human primates
-
Zimmerman, T. S., Lee, A. C. H., Akinc, A., Bramlage, B., Bumcrot, D., Fedoruk, M. N., Harborth, J., Heyes, J. A., Jeffs, L. B., John, M., Judge, A. D., Lam, K., McClintock, K., Nechev, L. V., Palmer, L. R., Racie, T., Röhl, I., Seiffert, S., Shanmugam, S., Sood, V., Soutschek, J., Toudjarska, I., Wheat, A. J., Yaworski, E., Zedalis, W., Koteliansky, V., Manoharan, M., Vornlocher, H.-P., and MacLachlan, I. (2006) RNAi-mediated gene silencing in non-human primates Nature 441, 111-114
-
(2006)
Nature
, vol.441
, pp. 111-114
-
-
Zimmerman, T.S.1
Lee, A.C.H.2
Akinc, A.3
Bramlage, B.4
Bumcrot, D.5
Fedoruk, M.N.6
Harborth, J.7
Heyes, J.A.8
Jeffs, L.B.9
John, M.10
Judge, A.D.11
Lam, K.12
McClintock, K.13
Nechev, L.V.14
Palmer, L.R.15
Racie, T.16
Röhl, I.17
Seiffert, S.18
Shanmugam, S.19
Sood, V.20
Soutschek, J.21
Toudjarska, I.22
Wheat, A.J.23
Yaworski, E.24
Zedalis, W.25
Koteliansky, V.26
Manoharan, M.27
Vornlocher, H.-P.28
MacLachlan, I.29
more..
-
21
-
-
23944464631
-
Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives
-
DOI 10.1002/jgm.773
-
Neu, M., Fischer, D., and Kissel, T. (2005) Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives J. Gene Med. 7, 992-1009 (Pubitemid 41195062)
-
(2005)
Journal of Gene Medicine
, vol.7
, Issue.8
, pp. 992-1009
-
-
Neu, M.1
Fischer, D.2
Kissel, T.3
-
22
-
-
34548818764
-
Cationic lipids and polymers mediated vectors for delivery of siRNA
-
DOI 10.1016/j.jconrel.2007.07.016, PII S0168365907003914
-
Zhang, S., Zhao, B., Jiang, H., Wang, B., and Ma, B. (2007) Cationic lipids and polymers mediated vectors for delivery of siRNA J. Controlled Release 123, 1-10 (Pubitemid 47444388)
-
(2007)
Journal of Controlled Release
, vol.123
, Issue.1
, pp. 1-10
-
-
Zhang, S.1
Zhao, B.2
Jiang, H.3
Wang, B.4
Ma, B.5
-
23
-
-
77957820261
-
RNAi and small interfering RNAs in human disease therapeutic applications
-
Lares, M. R., Rossi, J. J., and Ouellet, D. L. (2010) RNAi and small interfering RNAs in human disease therapeutic applications Trends Biotechnol. 28, 570-579
-
(2010)
Trends Biotechnol.
, vol.28
, pp. 570-579
-
-
Lares, M.R.1
Rossi, J.J.2
Ouellet, D.L.3
-
24
-
-
78449309070
-
Efficient and targeted delivery of siRNA in vivo
-
Shim, M. S. and Kwon, Y. J. (2010) Efficient and targeted delivery of siRNA in vivo FEBS J. 277, 4814-4827
-
(2010)
FEBS J.
, vol.277
, pp. 4814-4827
-
-
Shim, M.S.1
Kwon, Y.J.2
-
25
-
-
3042716509
-
Poly-β amino ester-containing microparticles enhance the activity of nonviral genetic vaccines
-
DOI 10.1073/pnas.0403549101
-
Little, S. R., Lynn, D. M., Ge, Q., Anderson, D. G., Puram, S. V., Chen, J., Eisen, H. N., and Langer, R. (2004) Poly-B-amino ester-containing microparticles enhance the activity of nonviral genetic vaccines Proc. Natl. Acad. Sci. U.S.A. 101, 9534-9539 (Pubitemid 38869271)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.26
, pp. 9534-9539
-
-
Little, S.R.1
Lynn, D.M.2
Ge, Q.3
Anderson, D.G.4
Puram, S.V.5
Chen, J.6
Eisen, H.N.7
Langer, R.8
-
26
-
-
66249083866
-
Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA
-
Woodrow, K. A., Cu, Y., Booth, C. J., Saucier-Sawyer, J. K., Wood, M. J., and Saltzman, W. M. (2009) Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA Nat. Mater. 8, 526-533
-
(2009)
Nat. Mater.
, vol.8
, pp. 526-533
-
-
Woodrow, K.A.1
Cu, Y.2
Booth, C.J.3
Saucier-Sawyer, J.K.4
Wood, M.J.5
Saltzman, W.M.6
-
27
-
-
56849117151
-
Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy
-
Nguyen, J., Steele, T. W. J., Merkel, O., Reul, R., and Kissel, T. (2008) Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy J. Controlled Release 132, 243-251
-
(2008)
J. Controlled Release
, vol.132
, pp. 243-251
-
-
Nguyen, J.1
Steele, T.W.J.2
Merkel, O.3
Reul, R.4
Kissel, T.5
-
28
-
-
1542333716
-
Molecularly engineered poly(ortho ester) microspheres for enhanced delivery of DNA vaccines
-
Wang, C., Ge, Q., Ting, D., Nguyen, D., Shen, H.-R., Chen, J., Eisen, H. N., Heller, J., Langer, R., and Putnam, D. (2004) Molecularly engineered poly(ortho ester) microspheres for enhanced delivery of DNA vaccines Nat. Mater. 3, 190-196
-
(2004)
Nat. Mater.
, vol.3
, pp. 190-196
-
-
Wang, C.1
Ge, Q.2
Ting, D.3
Nguyen, D.4
Shen, H.-R.5
Chen, J.6
Eisen, H.N.7
Heller, J.8
Langer, R.9
Putnam, D.10
-
29
-
-
75649119274
-
Solid polymeric microparticles enhance the delivery of siRNA to macrophages in vivo
-
Lee, S., Yang, S. C., Kao, C.-Y., Pierce, R. H., and Murthy, N. (2009) Solid polymeric microparticles enhance the delivery of siRNA to macrophages in vivo Nucleic Acids Res. 37, e145
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 145
-
-
Lee, S.1
Yang, S.C.2
Kao, C.-Y.3
Pierce, R.H.4
Murthy, N.5
-
30
-
-
25844443694
-
Formulation and characterization of poly (β amino ester) microparticles for genetic vaccine delivery
-
DOI 10.1016/j.jconrel.2005.04.022, PII S016836590500310X
-
Little, S. R., Lynn, D. M., Puram, S. V., and Langer, R. (2005) Formulation and characterization of poly (B amino ester) microparticles for genetic vaccine delivery J. Controlled Release 107, 449-462 (Pubitemid 41393354)
-
(2005)
Journal of Controlled Release
, vol.107
, Issue.3
, pp. 449-462
-
-
Little, S.R.1
Lynn, D.M.2
Puram, S.V.3
Langer, R.4
-
31
-
-
1642312018
-
Timing is everything
-
Pack, D. W. (2004) Timing is everything Nat. Mater. 3, 133-134
-
(2004)
Nat. Mater.
, vol.3
, pp. 133-134
-
-
Pack, D.W.1
-
32
-
-
0034006495
-
Visual evidence of acidic environment within degrading poly(lactic-co- glycolic acid) (PLGA) microspheres
-
DOI 10.1023/A:1007582911958
-
Fu, K., Pack, D. W., Klibanov, A. M., and Langer, R. (2000) Visual evidence of acidic environment within degrading poly(lactic-co-glycolic acid) (PLGA) microspheres Pharm. Res. 17, 100-106 (Pubitemid 30121107)
-
(2000)
Pharmaceutical Research
, vol.17
, Issue.1
, pp. 100-106
-
-
Fu, K.1
Pack, D.W.2
Klibanov, A.M.3
Langer, R.4
-
33
-
-
0032855232
-
Microencapsulation of DNA using poly(DL-lactide-co-glycolide): Stability issues and release characteristics
-
DOI 10.1016/S0168-3659(99)00151-0, PII S0168365999001510
-
Walter, E., Moelling, K., Pavlovic, J., and Merkle, H. P. (1999) Microencapsulation of DNA using poly(DL-lactide-co-glycolide): Stability issues and release characteristics J. Controlled Release 61, 361-374 (Pubitemid 29413030)
-
(1999)
Journal of Controlled Release
, vol.61
, Issue.3
, pp. 361-374
-
-
Walter, E.1
Moelling, K.2
Pavlovic, J.3
Merkle, H.P.4
-
34
-
-
34347245039
-
Functional polymers based on dextran
-
Heinze, T., Liebert, T., Heublein, B., and Hornig, S. (2006) Functional polymers based on dextran Adv. Polym. Sci. 205, 199-291
-
(2006)
Adv. Polym. Sci.
, vol.205
, pp. 199-291
-
-
Heinze, T.1
Liebert, T.2
Heublein, B.3
Hornig, S.4
-
35
-
-
66149148685
-
Biodegradable dextran nanogels for RNA interference: Focusing on endosomal escape and intracellular siRNA delivery
-
Raemdonck, K., Naeye, B., Buyens, K., Vandenbroucke, R. E., Høgset, A., Demeester, J., and De Smedt, S. C. (2009) Biodegradable dextran nanogels for RNA interference: Focusing on endosomal escape and intracellular siRNA delivery Adv. Funct. Mater. 19, 1406-1415
-
(2009)
Adv. Funct. Mater.
, vol.19
, pp. 1406-1415
-
-
Raemdonck, K.1
Naeye, B.2
Buyens, K.3
Vandenbroucke, R.E.4
Høgset, A.5
Demeester, J.6
De Smedt, S.C.7
-
36
-
-
77954314924
-
Prolonged gene silencing by combining siRNA nanogels and photochemical internalization
-
Raemdonck, K., Naeye, B., Høgset, A., Demeester, J., and De Smedt, S. C. (2010) Prolonged gene silencing by combining siRNA nanogels and photochemical internalization J. Controlled Release 145, 281-288
-
(2010)
J. Controlled Release
, vol.145
, pp. 281-288
-
-
Raemdonck, K.1
Naeye, B.2
Høgset, A.3
Demeester, J.4
De Smedt, S.C.5
-
37
-
-
77049122091
-
Promoted adipogenesis of rat mesenchymal stem cells by transfection of small interfering RNA complexed with a cationized dextran
-
Nagane, K., Jo, J.-I., and Tabata, Y. (2010) Promoted adipogenesis of rat mesenchymal stem cells by transfection of small interfering RNA complexed with a cationized dextran Tissue Eng., Part A 16, 21-31
-
(2010)
Tissue Eng., Part A
, vol.16
, pp. 21-31
-
-
Nagane, K.1
Jo, J.-I.2
Tabata, Y.3
-
38
-
-
49449098661
-
Acetal-derivatized dextran: An acid-responsive biodegradable material for therapeutic applications
-
Bachelder, E. M., Beaudette, T. T., Broaders, K. E., Dashe, J., and Fréchet, J. M. J. (2008) Acetal-derivatized dextran: An acid-responsive biodegradable material for therapeutic applications J. Am. Chem. Soc. 130, 10494-10495
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 10494-10495
-
-
Bachelder, E.M.1
Beaudette, T.T.2
Broaders, K.E.3
Dashe, J.4
Fréchet, J.M.J.5
-
39
-
-
65249187336
-
Acetalated dextran is a chemically and biologically tunable material for particulate immunotherapy
-
Broaders, K. E., Cohen, J. A., Beaudette, T. T., Bachelder, E. M., and Fréchet, J. M. J. (2009) Acetalated dextran is a chemically and biologically tunable material for particulate immunotherapy Proc. Natl. Acad. Sci. U.S.A. 106, 5497-5502
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 5497-5502
-
-
Broaders, K.E.1
Cohen, J.A.2
Beaudette, T.T.3
Bachelder, E.M.4
Fréchet, J.M.J.5
-
40
-
-
77953264382
-
In vitro analysis of acetalated dextran microparticles as a potent delivery platform for vaccine adjuvants
-
Bachelder, E. M., Beaudette, T. T., Broaders, K. E., Fréchet, J. M. J., Albrecht, M. T., Mateczun, A. J., Ainslie, K. M., Pesce, J. T., and Keane-Myers, A. M. (2010) In vitro analysis of acetalated dextran microparticles as a potent delivery platform for vaccine adjuvants Mol. Pharmaceutics 7, 826-835
-
(2010)
Mol. Pharmaceutics
, vol.7
, pp. 826-835
-
-
Bachelder, E.M.1
Beaudette, T.T.2
Broaders, K.E.3
Fréchet, J.M.J.4
Albrecht, M.T.5
Mateczun, A.J.6
Ainslie, K.M.7
Pesce, J.T.8
Keane-Myers, A.M.9
-
41
-
-
77955766504
-
Acetal-modified dextran microparticles with controlled degradation kinetics and surface functionality for gene delivery in phagocytic and non-phagocytic cells
-
Cohen, J. A., Beaudette, T. T., Cohen, J. L., Broaders, K. E., Bachelder, E. M., and Fréchet, J. M. J. (2010) Acetal-modified dextran microparticles with controlled degradation kinetics and surface functionality for gene delivery in phagocytic and non-phagocytic cells Adv. Mater. 22, 3593-3597
-
(2010)
Adv. Mater.
, vol.22
, pp. 3593-3597
-
-
Cohen, J.A.1
Beaudette, T.T.2
Cohen, J.L.3
Broaders, K.E.4
Bachelder, E.M.5
Fréchet, J.M.J.6
-
42
-
-
65749088084
-
SiRNA vs. shRNA: Similarities and differences
-
Rao, D. D., Vorhies, J. S., Senzer, N., and Nemunaitis, J. (2009) siRNA vs. shRNA: Similarities and differences Adv. Drug Delivery Rev. 61, 746-759
-
(2009)
Adv. Drug Delivery Rev.
, vol.61
, pp. 746-759
-
-
Rao, D.D.1
Vorhies, J.S.2
Senzer, N.3
Nemunaitis, J.4
-
43
-
-
34547228805
-
Polymer-based siRNA delivery: Perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery
-
DOI 10.1016/j.jconrel.2007.05.021, PII S0168365907002659
-
Gary, D. J., Puri, N., and Won, Y.-Y. (2007) Polymer-based siRNA delivery: Perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery J. Controlled Release 121, 64-73 (Pubitemid 47126065)
-
(2007)
Journal of Controlled Release
, vol.121
, Issue.1-2
, pp. 64-73
-
-
Gary, D.J.1
Puri, N.2
Won, Y.-Y.3
-
44
-
-
65749119809
-
Nonviral vector-mediated RNA interference: Its gene silencing characteristics and important factors to achieve RNAi-based gene therapy
-
Takahashi, Y., Nishikawa, M., and Takakura, Y. (2009) Nonviral vector-mediated RNA interference: Its gene silencing characteristics and important factors to achieve RNAi-based gene therapy Adv. Drug Delivery Rev. 61, 760-766
-
(2009)
Adv. Drug Delivery Rev.
, vol.61
, pp. 760-766
-
-
Takahashi, Y.1
Nishikawa, M.2
Takakura, Y.3
-
45
-
-
39649104546
-
Anti-tumor effects of anti-VEGF siRNA encapsulated with PLGA microspheres in mice
-
Murata, N., Takashima, Y., Toyoshima, K., Yamamoto, M., and Okada, H. (2008) Anti-tumor effects of anti-VEGF siRNA encapsulated with PLGA microspheres in mice J. Controlled Release 126, 246-254
-
(2008)
J. Controlled Release
, vol.126
, pp. 246-254
-
-
Murata, N.1
Takashima, Y.2
Toyoshima, K.3
Yamamoto, M.4
Okada, H.5
-
46
-
-
0025275020
-
Effect of the chemical modification of Dextran on the degradation by Dextranase
-
Vercauteren, R., Bruneel, D., Schacht, E., and Duncan, R. (1990) Effect of the chemical modification of dextran on the degradation by Dextranase J. Bioact. Compat. Polym. 5, 4-15 (Pubitemid 20150979)
-
(1990)
Journal of Bioactive and Compatible Polymers
, vol.5
, Issue.1
, pp. 4-15
-
-
Vercauteren, R.1
Bruneel, D.2
Schacht, E.3
Duncan, R.4
-
47
-
-
0026939267
-
Effect of the chemical modification of dextran on the degradation by rat liver lysosomal enzymes
-
DOI 10.1177/088391159200700404
-
Vercauteren, R., Schacht, E., and Duncan, R. (1992) Effect of the chemical modification of dextran on the degradation by rat liver lysosomal enzymes J. Bioact. Compat. Polym. 7, 346-357 (Pubitemid 23020212)
-
(1992)
Journal of Bioactive and Compatible Polymers
, vol.7
, Issue.4
, pp. 346-357
-
-
Vercauteren, R.1
Schacht, E.2
Duncan, R.3
-
48
-
-
0025824046
-
Enzymatic degradation and immunogenic properties of derivatized dextrans
-
Crepon, B., Jozefonvicz, J., Chytry, V., ihová, B., and Kopeek, J. (1991) Enzymatic degradation and immunogenic properties of derivatized dextrans Biomaterials 12, 550-554
-
(1991)
Biomaterials
, vol.12
, pp. 550-554
-
-
Crepon, B.1
Jozefonvicz, J.2
Chytry, V.3
Ihová, B.4
Kopeek, J.5
-
49
-
-
1642360912
-
Metabolism of plasma expanders studied with carbon-14-labeled dextran
-
Gray, I. (1953) Metabolism of plasma expanders studied with carbon-14-labeled dextran Am. J. Physiol. 174, 462-466
-
(1953)
Am. J. Physiol.
, vol.174
, pp. 462-466
-
-
Gray, I.1
-
50
-
-
0004109170
-
Medical Applications of Dextran and Its Derivatives
-
Dumitriu, S., Ed., Chapter 16, Marcel Dekker, New York
-
de Belder, A. N. (1996) Medical Applications of Dextran and Its Derivatives. Polysaccharides in Medicinal Applications (Dumitriu, S., Ed.) pp 505-524, Chapter 16, Marcel Dekker, New York.
-
(1996)
Polysaccharides in Medicinal Applications
, pp. 505-524
-
-
De Belder, A.N.1
-
51
-
-
0000618419
-
The splitting of dextran and isomaltose by animal tissues
-
Rosenfeld, E. L. and Lukomskaya, I. S. (1957) The splitting of dextran and isomaltose by animal tissues Clin. Chim. Acta 2, 105-114
-
(1957)
Clin. Chim. Acta
, vol.2
, pp. 105-114
-
-
Rosenfeld, E.L.1
Lukomskaya, I.S.2
-
52
-
-
0342736832
-
Metabolism in vivo of clinical dextran
-
Rosenfeld, E. L. and Saienko, A. S. (1964) Metabolism in vivo of clinical dextran Clin. Chim. Acta 10, 223-228
-
(1964)
Clin. Chim. Acta
, vol.10
, pp. 223-228
-
-
Rosenfeld, E.L.1
Saienko, A.S.2
-
53
-
-
0034623567
-
Degradable poly(B-amino esters): Synthesis, characterization, and self-assembly with plasmid DNA
-
Lynn, D. M. and Langer, R. (2000) Degradable poly(B-amino esters): Synthesis, characterization, and self-assembly with plasmid DNA J. Am. Chem. Soc. 122, 10761-10768
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 10761-10768
-
-
Lynn, D.M.1
Langer, R.2
-
54
-
-
0037171852
-
Polysaccharide-oligoamine based conjugates for gene delivery
-
DOI 10.1021/jm0105528
-
Azzam, T., Eliyahu, H., Shapira, L., Linial, M., Barenholz, Y., and Domb, A. J. (2002) Polysaccharide-oligoamine based conjugates for gene delivery J. Med. Chem. 45, 1817-1824 (Pubitemid 34415377)
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, Issue.9
, pp. 1817-1824
-
-
Azzam, T.1
Eliyahu, H.2
Shapira, L.3
Linial, M.4
Barenholz, Y.5
Domb, A.J.6
-
55
-
-
1842638512
-
Hydrophobized dextran-spermine conjugate as potential vector for in vitro gene transfection
-
DOI 10.1016/j.jconrel.2004.01.022, PII S0168365904000434
-
Azzam, T., Eliyahu, H., Makovitzki, A., Linial, M., and Domb, A. J. (2004) Hydrophobized dextran-spermine conjugate as potential vector for in vitro gene transfection J. Controlled Release 96, 309-323 (Pubitemid 38481512)
-
(2004)
Journal of Controlled Release
, vol.96
, Issue.2
, pp. 309-323
-
-
Azzam, T.1
Eliyahu, H.2
Makovitzki, A.3
Linial, M.4
Domb, A.J.5
-
56
-
-
0742324370
-
Dextran-spermine polycation: An efficient nonviral vector for in vitro and in vivo gene transfection
-
DOI 10.1038/sj.gt.3302159
-
Hosseinkhani, H., Azzam, T., Tabata, Y., and Domb, A. J. (2004) Dextran-spermine polycation: An efficient nonviral vector for in vitro and in vivo gene transfection Gene Ther. 11, 194-203 (Pubitemid 38159692)
-
(2004)
Gene Therapy
, vol.11
, Issue.2
, pp. 194-203
-
-
Hosseinkhani, H.1
Azzam, T.2
Tabata, Y.3
Domb, A.J.4
-
57
-
-
0017874190
-
Higher antitumor efficacy of daunomycin linked to dextran
-
Bernstein, A., Hurwitz, E., Maron, R., Arnon, R., Sela, M., and Wilchek, M. (1978) Higher antitumor efficacy of daunomycin linked to dextran J. Natl. Cancer Inst. 60, 379-383
-
(1978)
J. Natl. Cancer Inst.
, vol.60
, pp. 379-383
-
-
Bernstein, A.1
Hurwitz, E.2
Maron, R.3
Arnon, R.4
Sela, M.5
Wilchek, M.6
-
58
-
-
77955175216
-
Strategies in the design of nanoparticles for therapeutic applications
-
Petros, R. A. and DeSimone, J. M. (2010) Strategies in the design of nanoparticles for therapeutic applications Nat. Rev. Drug Discovery 9, 615-627
-
(2010)
Nat. Rev. Drug Discovery
, vol.9
, pp. 615-627
-
-
Petros, R.A.1
Desimone, J.M.2
-
59
-
-
0034980741
-
Transgene expression in mouse airway epithelium by aerosol gene therapy with PEI-DNA complexes
-
DOI 10.1006/mthe.2001.0300
-
Gautam, A., Densmore, C. L., Golunski, E., Xu, B., and Waldrep, J. C. (2001) Transgene expression in mouse airway epithelium by aerosol gene therapy with PEI/DNA complexes Mol. Ther. 3, 551-556 (Pubitemid 32509849)
-
(2001)
Molecular Therapy
, vol.3
, Issue.4
, pp. 551-556
-
-
Gautam, A.1
Densmore, C.L.2
Golunski, E.3
Xu, B.4
Waldrep, J.C.5
-
60
-
-
68549110154
-
The suppression of lung tumorigenesis by aerosol-delivered folate-chitosan-graft-polyethyleneimine/Akt1 shRNA complexes through the Akt signaling pathway
-
Jiang, H.-L., Xu, C.-X., Kim, Y.-K., Arote, R., Jere, D., Lim, H.-T., Cho, M.-H., and Cho, C.-S. (2009) The suppression of lung tumorigenesis by aerosol-delivered folate-chitosan-graft-polyethyleneimine/Akt1 shRNA complexes through the Akt signaling pathway Biomaterials 30, 5844-5852
-
(2009)
Biomaterials
, vol.30
, pp. 5844-5852
-
-
Jiang, H.-L.1
Xu, C.-X.2
Kim, Y.-K.3
Arote, R.4
Jere, D.5
Lim, H.-T.6
Cho, M.-H.7
Cho, C.-S.8
-
61
-
-
77957809398
-
-
Massachusetts Institute of Technology, Cambridge
-
Fuller, J. E. (2008) in Chemical Engineering, Massachusetts Institute of Technology, Cambridge.
-
(2008)
Chemical Engineering
-
-
Fuller, J.E.1
-
62
-
-
2342530994
-
Advanced transfection with Lipofectamine 2000 reagent: Primary neurons, siRNA, and high-throughput applications
-
DOI 10.1016/j.ymeth.2003.11.023, PII S1046202303003001
-
Dalby, B., Cates, S., Harris, A., Ohki, E. C., Tilkins, M. L., Price, P. J., and Ciccarone, V. C. (2004) Advanced transfection with Lipofectamine 2000 reagent: Primary neurons, siRNA, and high-throughput applications Methods 33, 95-103 (Pubitemid 38569654)
-
(2004)
Methods
, vol.33
, Issue.2
, pp. 95-103
-
-
Dalby, B.1
Cates, S.2
Harris, A.3
Ohki, E.C.4
Tilkins, M.L.5
Price, P.J.6
Ciccarone, V.C.7
-
63
-
-
44249116184
-
Dependence of reactive oxygen species and FLICE inhibitory protein on Lipofectamine-induced apoptosis in human lung epithelial cells
-
DOI 10.1124/jpet.107.136077
-
Kongkaneramit, L., Sarisuta, N., Azad, N., Lu, Y., Iyer, A. K. V., Wang, L., and Rojanasakul, Y. (2008) Dependence of reactive oxygen species and FLICE inhibitory protein on Lipofectamine-induced apoptosis in human lung epithelial cells J. Pharmacol. Exp. Ther. 325, 969-977 (Pubitemid 351724344)
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.325
, Issue.3
, pp. 969-977
-
-
Kongkaneramit, L.1
Sarisuta, N.2
Azad, N.3
Lu, Y.4
Iyer, A.K.V.5
Wang, L.6
Rojanasakul, Y.7
-
64
-
-
68049105399
-
Chemoselective ligation in the functionalization of polysaccharide-based particles
-
Beaudette, T. T., Cohen, J. A., Bachelder, E. M., Broaders, K. E., Cohen, J. L., Engleman, E. G., and Fréchet, J. M. J. (2009) Chemoselective ligation in the functionalization of polysaccharide-based particles J. Am. Chem. Soc. 131, 10360-10361
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 10360-10361
-
-
Beaudette, T.T.1
Cohen, J.A.2
Bachelder, E.M.3
Broaders, K.E.4
Cohen, J.L.5
Engleman, E.G.6
Fréchet, J.M.J.7
|