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Volumn 53, Issue 44, 2014, Pages 11822-11827

Adaptive amphiphilic dendrimer-based nanoassemblies as robust and versatile siRNA delivery systems

Author keywords

Dendrimers; Gene silencing; Nanocarriers; Nonviral vectors; Self assembly

Indexed keywords

CELL CULTURE; DENDRIMERS; DRUG DELIVERY; GENE THERAPY; MEDICAL APPLICATIONS; RNA; SELF ASSEMBLY; STEM CELLS; SUPRAMOLECULAR CHEMISTRY;

EID: 84919388693     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201406764     Document Type: Article
Times cited : (182)

References (22)
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    • Angew. Chem. 2012, 124, 8606-8612.
    • (2012) Angew. Chem. , vol.124 , pp. 8606-8612
  • 15
    • 84919376549 scopus 로고    scopus 로고
    • Dicersubstrate siRNAs (dsiRNAs) can be designed to be optimally processed by dicer with a view to generating higher and more durable RNAi potency, outperforming the conventional siRNA
    • Dicersubstrate siRNAs (dsiRNAs) can be designed to be optimally processed by dicer with a view to generating higher and more durable RNAi potency, outperforming the conventional siRNA.
  • 18
    • 84919376548 scopus 로고    scopus 로고
    • Trans IT-TKO (TKO) showed significant toxicity on human primary peripheral blood mononuclear cells (PBMC-CD4 + cells), human hematopoietic stem cells (HSC-CD34 +), and human glioblastoma stem cells (GSC). The growth of these cells was adversely affected; hence, considerably reduced total RNA or no total RNA could be recovered from these cells following treatment with Trans IT-TKO (TKO)
    • Trans IT-TKO (TKO) showed significant toxicity on human primary peripheral blood mononuclear cells (PBMC-CD4 + cells), human hematopoietic stem cells (HSC-CD34 +), and human glioblastoma stem cells (GSC). The growth of these cells was adversely affected; hence, considerably reduced total RNA or no total RNA could be recovered from these cells following treatment with Trans IT-TKO (TKO).
  • 20
    • 78650476432 scopus 로고    scopus 로고
    • J. P. Behr, Chimia 1997, 51, 34-36.
    • (1997) Chimia , vol.51 , pp. 34-36
    • Behr, J.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.