PHD/HIF-1 upregulates CA12 to protect against degenerative disc disease: A human sample, in vitro and ex vivo study

Laboratory Investigation

Volumn 96, Issue 5, 2016, Pages 561-569

  Chen, Shuai ^a,b   Fang, Xiang Qian ^a,b   Wang, Qiang ^a,b   Wang, Shao Wei ^a,b   Hu, Zhi Jun ^a,b   Zhou, Zhi Jie ^a,b   Xu, Wen Bing ^a,b   Wang, Ji Ying ^a,b   Qin, An ^c   Fan, Shun Wu ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b Key Laboratory of Biotherapy of Zhejiang Province   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONATE DEHYDRATASE XII; DIMETHYLOXALYLGLYCINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; OXYGENASE INHIBITOR; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CARBONATE DEHYDRATASE; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HIF1A PROTEIN, HUMAN; HIF1A PROTEIN, RAT; MESSENGER RNA;

ADULT; AGED; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BIOSYNTHESIS; EX VIVO STUDY; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INTERVERTEBRAL DISK DEGENERATION; MAJOR CLINICAL STUDY; MALE; NONHUMAN; NUCLEUS PULPOSUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; TISSUE SECTION; UPREGULATION; WESTERN BLOTTING; ADOLESCENT; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL HYPOXIA; CYTOLOGY; GENE KNOCKDOWN; GENETICS; METABOLISM; MIDDLE AGED; PHYSIOLOGY; SPRAGUE DAWLEY RAT; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARBONIC ANHYDRASES; CELL HYPOXIA; CELLS, CULTURED; FEMALE; GENE KNOCKDOWN TECHNIQUES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERVERTEBRAL DISC DEGENERATION; MALE; MIDDLE AGED; NUCLEUS PULPOSUS; PROLYL HYDROXYLASES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; UP-REGULATION; YOUNG ADULT;

EID: 84964773874     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2016.32     Document Type: Article

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