메뉴 건너뛰기




Volumn 16, Issue 3, 2014, Pages

Novel immortal human cell lines reveal subpopulations in the nucleus pulposus

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A12; CD24 ANTIGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; CYTOKERATIN 19; MESSENGER RNA; PLEIOTROPHIN; TELOMERASE REVERSE TRANSCRIPTASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXF1; TRANSCRIPTION FACTOR PAX1; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; VIRUS LARGE T ANTIGEN; ACAN PROTEIN, HUMAN; AGGRECAN; CARRIER PROTEIN; COL2A1 PROTEIN, HUMAN; COLLAGEN TYPE I, ALPHA 1 CHAIN; CYTOKINE; FORKHEAD TRANSCRIPTION FACTOR; FOXF1 PROTEIN, HUMAN; PAIRED BOX TRANSCRIPTION FACTOR; PAX1 TRANSCRIPTION FACTOR; SOX9 PROTEIN, HUMAN;

EID: 84902908732     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar4597     Document Type: Article
Times cited : (40)

References (70)
  • 1
    • 37349041034 scopus 로고    scopus 로고
    • A systematic review of low back pain cost of illness studies in the United States and internationally
    • Dagenais S, Caro J, Haldeman S. A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J 2008, 8:8-20.
    • (2008) Spine J , vol.8 , pp. 8-20
    • Dagenais, S.1    Caro, J.2    Haldeman, S.3
  • 2
    • 0036216444 scopus 로고    scopus 로고
    • Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs
    • Sive JI, Baird P, Jeziorsk M, Watkins A, Hoyland JA, Freemont AJ. Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs. Mol Pathol 2002, 55:91-97.
    • (2002) Mol Pathol , vol.55 , pp. 91-97
    • Sive, J.I.1    Baird, P.2    Jeziorsk, M.3    Watkins, A.4    Hoyland, J.A.5    Freemont, A.J.6
  • 3
    • 78650060236 scopus 로고    scopus 로고
    • Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation
    • Minogue BM, Richardson SM, Zeef LAH, Freemont AJ, Hoyland JA. Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation. Arthritis Rheum 2010, 62:3695-3705.
    • (2010) Arthritis Rheum , vol.62 , pp. 3695-3705
    • Minogue, B.M.1    Richardson, S.M.2    Zeef, L.A.H.3    Freemont, A.J.4    Hoyland, J.A.5
  • 5
    • 76549130659 scopus 로고    scopus 로고
    • Variations in gene and protein expression in human nucleus pulposus in comparison with annulus fibrosus and cartilage cells: potential associations with aging and degeneration
    • Rutges J, Creemers LB, Dhert W, Milz S, Sakai D, Mochida J, Alini M, Grad S. Variations in gene and protein expression in human nucleus pulposus in comparison with annulus fibrosus and cartilage cells: potential associations with aging and degeneration. Osteoarthritis Cartilage 2009, 18:416-423.
    • (2009) Osteoarthritis Cartilage , vol.18 , pp. 416-423
    • Rutges, J.1    Creemers, L.B.2    Dhert, W.3    Milz, S.4    Sakai, D.5    Mochida, J.6    Alini, M.7    Grad, S.8
  • 6
    • 0038300772 scopus 로고    scopus 로고
    • Degeneration of the intervertebral disc
    • Urban JP, Roberts S. Degeneration of the intervertebral disc. Arthritis Res Ther 2003, 5:120-130.
    • (2003) Arthritis Res Ther , vol.5 , pp. 120-130
    • Urban, J.P.1    Roberts, S.2
  • 7
    • 84867990014 scopus 로고    scopus 로고
    • Diversity of intervertebral disc cells: phenotype and function
    • Pattappa G, Li Z, Peroglio M, Wismer N, Alini M, Grad S. Diversity of intervertebral disc cells: phenotype and function. J Anat 2012, 221:480-496.
    • (2012) J Anat , vol.221 , pp. 480-496
    • Pattappa, G.1    Li, Z.2    Peroglio, M.3    Wismer, N.4    Alini, M.5    Grad, S.6
  • 11
    • 78349311099 scopus 로고    scopus 로고
    • Immunohistochemical identification of notochordal markers in cells in the aging human lumbar intervertebral disc
    • Weiler C, Nerlich A, Schaaf R, Bachmeier B, Wuertz K, Boos N. Immunohistochemical identification of notochordal markers in cells in the aging human lumbar intervertebral disc. Eur Spine J 2010, 19:1761-1770.
    • (2010) Eur Spine J , vol.19 , pp. 1761-1770
    • Weiler, C.1    Nerlich, A.2    Schaaf, R.3    Bachmeier, B.4    Wuertz, K.5    Boos, N.6
  • 12
    • 3242672324 scopus 로고    scopus 로고
    • Immortalization of human nucleus pulposus cells by a recombinant SV40 adenovirus vector: establishment of a novel cell line for the study of human nucleus pulposus cells
    • Sakai D, Mochida J, Yamamoto Y, Toh E, Iwashina T, Miyazaki T, Inokuchi S, Ando K, Hotta T. Immortalization of human nucleus pulposus cells by a recombinant SV40 adenovirus vector: establishment of a novel cell line for the study of human nucleus pulposus cells. Spine (Phila Pa 1976) 2004, 29:1515-1523.
    • (2004) Spine (Phila Pa 1976) , vol.29 , pp. 1515-1523
    • Sakai, D.1    Mochida, J.2    Yamamoto, Y.3    Toh, E.4    Iwashina, T.5    Miyazaki, T.6    Inokuchi, S.7    Ando, K.8    Hotta, T.9
  • 15
    • 0034792246 scopus 로고    scopus 로고
    • Genome-wide analysis of sixteen chordomas by comparative genomic hybridization and cytogenetics of the first human chordoma cell line, U-CH1
    • Scheil S, Brüderlein S, Liehr T, Starke H, Herms J, Schulte M, Möller P. Genome-wide analysis of sixteen chordomas by comparative genomic hybridization and cytogenetics of the first human chordoma cell line, U-CH1. Genes Chromosomes Cancer 2001, 32:203-211.
    • (2001) Genes Chromosomes Cancer , vol.32 , pp. 203-211
    • Scheil, S.1    Brüderlein, S.2    Liehr, T.3    Starke, H.4    Herms, J.5    Schulte, M.6    Möller, P.7
  • 16
    • 0025352187 scopus 로고
    • Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
    • Morgenstern JP, Land H. Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res 1990, 18:3587-3596.
    • (1990) Nucleic Acids Res , vol.18 , pp. 3587-3596
    • Morgenstern, J.P.1    Land, H.2
  • 17
    • 0029833422 scopus 로고    scopus 로고
    • Episomal vectors rapidly and stably produce high-titer recombinant retrovirus
    • Kinsella T, Nolan G. Episomal vectors rapidly and stably produce high-titer recombinant retrovirus. Hum Gene Ther 1996, 7:1405-1413.
    • (1996) Hum Gene Ther , vol.7 , pp. 1405-1413
    • Kinsella, T.1    Nolan, G.2
  • 18
    • 0344252789 scopus 로고
    • Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP)
    • Piatyszek M, Kim N, Weinrich S, Hiyama K, Hiyama E, Wright W, Shay J. Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP). Methods Cell Sci 1995, 17:1-15.
    • (1995) Methods Cell Sci , vol.17 , pp. 1-15
    • Piatyszek, M.1    Kim, N.2    Weinrich, S.3    Hiyama, K.4    Hiyama, E.5    Wright, W.6    Shay, J.7
  • 19
    • 0033620651 scopus 로고    scopus 로고
    • Expression of the heparan sulfate proteoglycan, perlecan, during mouse embryogenesis and perlecan chondrogenic activity in vitro
    • French MM, Smith SE, Akanbi K, Sanford T, Hecht J, Farach-Carson MC, Carson DD. Expression of the heparan sulfate proteoglycan, perlecan, during mouse embryogenesis and perlecan chondrogenic activity in vitro. J Cell Biol 1999, 145:1103-1115.
    • (1999) J Cell Biol , vol.145 , pp. 1103-1115
    • French, M.M.1    Smith, S.E.2    Akanbi, K.3    Sanford, T.4    Hecht, J.5    Farach-Carson, M.C.6    Carson, D.D.7
  • 23
    • 0022552896 scopus 로고
    • Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue
    • Farndale RW, Buttle DJ, Barrett AJ. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta 1986, 883:173-177.
    • (1986) Biochim Biophys Acta , vol.883 , pp. 173-177
    • Farndale, R.W.1    Buttle, D.J.2    Barrett, A.J.3
  • 24
    • 0019124982 scopus 로고
    • Monitoring of collagen and collagen fragments in chromatography of protein mixtures
    • Huszar G, Maiocco J, Naftolin F. Monitoring of collagen and collagen fragments in chromatography of protein mixtures. Anal Biochem 1980, 105:424-429.
    • (1980) Anal Biochem , vol.105 , pp. 424-429
    • Huszar, G.1    Maiocco, J.2    Naftolin, F.3
  • 25
    • 27144470232 scopus 로고    scopus 로고
    • Human anulus fibrosis and nucleus pulposus cells of the intervertebral disc: effect of degeneration and culture system on cell phenotype
    • Kluba T, Niemeyer T, Gaissmaier C, Grunder T. Human anulus fibrosis and nucleus pulposus cells of the intervertebral disc: effect of degeneration and culture system on cell phenotype. Spine 2005, 30:2743-2748.
    • (2005) Spine , vol.30 , pp. 2743-2748
    • Kluba, T.1    Niemeyer, T.2    Gaissmaier, C.3    Grunder, T.4
  • 26
    • 0035881728 scopus 로고    scopus 로고
    • Intervertebral disc cells exhibit differences in gene expression in alginate and monolayer culture
    • Wang J, Baer A, Kraus V, Setton L. Intervertebral disc cells exhibit differences in gene expression in alginate and monolayer culture. Spine 2001, 26:1747-1751.
    • (2001) Spine , vol.26 , pp. 1747-1751
    • Wang, J.1    Baer, A.2    Kraus, V.3    Setton, L.4
  • 28
    • 0018221370 scopus 로고
    • Independent regulation of collagen types by chondrocytes during the loss of differentiated function in culture
    • Benya PD, Padilla SR, Nimni ME. Independent regulation of collagen types by chondrocytes during the loss of differentiated function in culture. Cell 1978, 15:1313-1321.
    • (1978) Cell , vol.15 , pp. 1313-1321
    • Benya, P.D.1    Padilla, S.R.2    Nimni, M.E.3
  • 29
    • 0017723046 scopus 로고
    • Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture
    • von der Mark K, Gauss V, von der Mark H, Müller P. Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture. Nature 1977, 267:531-532.
    • (1977) Nature , vol.267 , pp. 531-532
    • von der Mark, K.1    Gauss, V.2    von der Mark, H.3    Müller, P.4
  • 30
    • 37249032718 scopus 로고    scopus 로고
    • A phenotypic comparison of intervertebral disc and articular cartilage cells in the rat
    • Lee CR, Sakai D, Nakai T, Toyama K, Mochida J, Alini M, Grad S. A phenotypic comparison of intervertebral disc and articular cartilage cells in the rat. Eur Spine J 2007, 16:2174-2185.
    • (2007) Eur Spine J , vol.16 , pp. 2174-2185
    • Lee, C.R.1    Sakai, D.2    Nakai, T.3    Toyama, K.4    Mochida, J.5    Alini, M.6    Grad, S.7
  • 31
    • 70449535552 scopus 로고    scopus 로고
    • Human intervertebral disc-derived cells are recruited by human serum and form nucleus pulposus-like tissue upon stimulation with TGF-β3 or hyaluronan in vitro
    • Haberstroh K, Enz A, Zenclussen ML, Hegewald AA, Neumann K, Abbushi A, Thomé C, Sittinger M, Endres M, Kaps C. Human intervertebral disc-derived cells are recruited by human serum and form nucleus pulposus-like tissue upon stimulation with TGF-β3 or hyaluronan in vitro. Tissue Cell 2009, 41:414-420.
    • (2009) Tissue Cell , vol.41 , pp. 414-420
    • Haberstroh, K.1    Enz, A.2    Zenclussen, M.L.3    Hegewald, A.A.4    Neumann, K.5    Abbushi, A.6    Thomé, C.7    Sittinger, M.8    Endres, M.9    Kaps, C.10
  • 34
    • 0033767175 scopus 로고    scopus 로고
    • CD44 expression in the developing and growing rat intervertebral disc
    • Stevens JW, Kurriger GL, Carter AS, Maynard JA. CD44 expression in the developing and growing rat intervertebral disc. Dev Dyn 2000, 219:381-390.
    • (2000) Dev Dyn , vol.219 , pp. 381-390
    • Stevens, J.W.1    Kurriger, G.L.2    Carter, A.S.3    Maynard, J.A.4
  • 35
    • 84871270841 scopus 로고    scopus 로고
    • Changes in the molecular phenotype of nucleus pulposus cells with intervertebral disc aging
    • Tang X, Jing L, Chen J. Changes in the molecular phenotype of nucleus pulposus cells with intervertebral disc aging. PLoS One 2012, 7:e52020.
    • (2012) PLoS One , vol.7
    • Tang, X.1    Jing, L.2    Chen, J.3
  • 36
    • 34548489858 scopus 로고    scopus 로고
    • Regulation of chondrocyte differentiation by the actin cytoskeleton and adhesive interactions
    • Woods A, Wang G, Beier F. Regulation of chondrocyte differentiation by the actin cytoskeleton and adhesive interactions. J Cell Physiol 2007, 213:1-8.
    • (2007) J Cell Physiol , vol.213 , pp. 1-8
    • Woods, A.1    Wang, G.2    Beier, F.3
  • 37
    • 84905010915 scopus 로고    scopus 로고
    • Biochemical composition and turnover of the extracellular matrix of the normal and degenerate intervertebral disc
    • Sivan SS, Hayes AJ, Wachtel E, Caterson B, Merkher Y, Maroudas A, Brown S, Roberts S. Biochemical composition and turnover of the extracellular matrix of the normal and degenerate intervertebral disc. Eur Spine J 2014, 23:344-353.
    • (2014) Eur Spine J , vol.23 , pp. 344-353
    • Sivan, S.S.1    Hayes, A.J.2    Wachtel, E.3    Caterson, B.4    Merkher, Y.5    Maroudas, A.6    Brown, S.7    Roberts, S.8
  • 38
    • 84884560038 scopus 로고    scopus 로고
    • Differentiation of mouse induced pluripotent stem cells (iPSCs) into nucleus pulposus-like cells in vitro
    • Chen J, Lee EJ, Jing L, Christoforou N, Leong KW, Setton LA. Differentiation of mouse induced pluripotent stem cells (iPSCs) into nucleus pulposus-like cells in vitro. PLoS One 2013, 8:e75548.
    • (2013) PLoS One , vol.8
    • Chen, J.1    Lee, E.J.2    Jing, L.3    Christoforou, N.4    Leong, K.W.5    Setton, L.A.6
  • 39
    • 36049038011 scopus 로고    scopus 로고
    • Passage and reversal effects on gene expression of bovine meniscal fibrochondrocytes
    • Gunja N, Athanasiou K. Passage and reversal effects on gene expression of bovine meniscal fibrochondrocytes. Arthritis Res Ther 2007, 9:R93.
    • (2007) Arthritis Res Ther , vol.9
    • Gunja, N.1    Athanasiou, K.2
  • 40
    • 78649411146 scopus 로고    scopus 로고
    • Aggregation of bovine anterior cruciate ligament fibroblasts or marrow stromal cells promotes aggrecan production
    • Lim JJ, Scott L, Temenoff JS. Aggregation of bovine anterior cruciate ligament fibroblasts or marrow stromal cells promotes aggrecan production. Biotechnol Bioeng 2011, 108:151-162.
    • (2011) Biotechnol Bioeng , vol.108 , pp. 151-162
    • Lim, J.J.1    Scott, L.2    Temenoff, J.S.3
  • 41
    • 80455174499 scopus 로고    scopus 로고
    • Extracellular matrix ligand and stiffness modulate immature nucleus pulposus cell-cell interactions
    • Gilchrist CL, Darling EM, Chen J, Setton LA. Extracellular matrix ligand and stiffness modulate immature nucleus pulposus cell-cell interactions. PLoS One 2011, 6:e27170.
    • (2011) PLoS One , vol.6
    • Gilchrist, C.L.1    Darling, E.M.2    Chen, J.3    Setton, L.A.4
  • 42
    • 12344260899 scopus 로고    scopus 로고
    • Distinction between the extracellular matrix of the nucleus pulposus and hyaline cartilage: a requisite for tissue engineering of intervertebral disc
    • Mwale F, Roughley P, Antoniou J. Distinction between the extracellular matrix of the nucleus pulposus and hyaline cartilage: a requisite for tissue engineering of intervertebral disc. Eur Cell Mater 2004, 8:58-64.
    • (2004) Eur Cell Mater , vol.8 , pp. 58-64
    • Mwale, F.1    Roughley, P.2    Antoniou, J.3
  • 43
    • 77949455250 scopus 로고    scopus 로고
    • Differential expression level of cytokeratin 8 in cells of the bovine nucleus pulposus complicates the search for specific intervertebral disc cell markers
    • Gilson A, Dreger M, Urban J. Differential expression level of cytokeratin 8 in cells of the bovine nucleus pulposus complicates the search for specific intervertebral disc cell markers. Arthritis Res Ther 2010, 12:R24.
    • (2010) Arthritis Res Ther , vol.12
    • Gilson, A.1    Dreger, M.2    Urban, J.3
  • 44
    • 70350772321 scopus 로고    scopus 로고
    • Expression of laminin isoforms, receptors and binding proteins unique to nucleus pulposus cells of immature intervertebral disc
    • Chen J, Jing L, Gilchrist C, Richardson W, Fitch R, Setton L. Expression of laminin isoforms, receptors and binding proteins unique to nucleus pulposus cells of immature intervertebral disc. Connect Tissue Res 2009, 50:294-306.
    • (2009) Connect Tissue Res , vol.50 , pp. 294-306
    • Chen, J.1    Jing, L.2    Gilchrist, C.3    Richardson, W.4    Fitch, R.5    Setton, L.6
  • 45
    • 80053157000 scopus 로고    scopus 로고
    • Role of hypoxia and growth and differentiation factor-5 on differentiation of human mesenchymal stem cells towards intervertebral nucleus pulposus-like cells
    • Stoyanov J, Gantenbein-Ritter B, Bertolo A, Aebli N, Baur M, M Alini M, Grad S. Role of hypoxia and growth and differentiation factor-5 on differentiation of human mesenchymal stem cells towards intervertebral nucleus pulposus-like cells. Eur Cell Mater 2011, 21:533-547.
    • (2011) Eur Cell Mater , vol.21 , pp. 533-547
    • Stoyanov, J.1    Gantenbein-Ritter, B.2    Bertolo, A.3    Aebli, N.4    Baur, M.5    Alini, M.M.6    Grad, S.7
  • 46
    • 84896795857 scopus 로고    scopus 로고
    • Identification of novel nucleus pulposus markers: Interspecies variations and implications for cell-based therapies for intervertebral disc degeneration
    • Rodrigues-Pinto R, Richardson SM, Hoyland JA. Identification of novel nucleus pulposus markers: Interspecies variations and implications for cell-based therapies for intervertebral disc degeneration. Bone Joint Res 2013, 2:169-178.
    • (2013) Bone Joint Res , vol.2 , pp. 169-178
    • Rodrigues-Pinto, R.1    Richardson, S.M.2    Hoyland, J.A.3
  • 47
    • 34247592954 scopus 로고    scopus 로고
    • Juvenile degenerative disc disease: a report of 76 cases identified by magnetic resonance imaging
    • Dimar JR, Glassman SD, Carreon LY. Juvenile degenerative disc disease: a report of 76 cases identified by magnetic resonance imaging. Spine J 2007, 7:332-337.
    • (2007) Spine J , vol.7 , pp. 332-337
    • Dimar, J.R.1    Glassman, S.D.2    Carreon, L.Y.3
  • 48
    • 34548620230 scopus 로고    scopus 로고
    • The cell biology of intervertebral disc aging and degeneration
    • Zhao CQ, Wang LM, Jiang LS, Dai LY. The cell biology of intervertebral disc aging and degeneration. Ageing Res Rev 2007, 6:247-261.
    • (2007) Ageing Res Rev , vol.6 , pp. 247-261
    • Zhao, C.Q.1    Wang, L.M.2    Jiang, L.S.3    Dai, L.Y.4
  • 50
    • 34249788140 scopus 로고    scopus 로고
    • Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
    • Le Maitre CL, Freemont AJ, Hoyland JA. Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration. Arthritis Res Ther 2007, 9:R45.
    • (2007) Arthritis Res Ther , vol.9
    • Le Maitre, C.L.1    Freemont, A.J.2    Hoyland, J.A.3
  • 51
    • 67651083411 scopus 로고    scopus 로고
    • Senescence mechanisms of nucleus pulposus chondrocytes in human intervertebral discs
    • Kim KW, Chung HN, Ha KY, Lee JS, Kim YY. Senescence mechanisms of nucleus pulposus chondrocytes in human intervertebral discs. Spine J 2009, 9:658-666.
    • (2009) Spine J , vol.9 , pp. 658-666
    • Kim, K.W.1    Chung, H.N.2    Ha, K.Y.3    Lee, J.S.4    Kim, Y.Y.5
  • 52
    • 79951912532 scopus 로고    scopus 로고
    • Four faces of cellular senescence
    • Rodier F, Campisi J. Four faces of cellular senescence. J Cell Biol 2011, 192:547-556.
    • (2011) J Cell Biol , vol.192 , pp. 547-556
    • Rodier, F.1    Campisi, J.2
  • 53
    • 84863039944 scopus 로고    scopus 로고
    • Human Schwann cells retain essential phenotype characteristics after immortalization
    • Lehmann HC, Chen W, Mi R, Wang S, Liu Y, Rao M, Hoke A. Human Schwann cells retain essential phenotype characteristics after immortalization. Stem Cells Dev 2012, 21:423-431.
    • (2012) Stem Cells Dev , vol.21 , pp. 423-431
    • Lehmann, H.C.1    Chen, W.2    Mi, R.3    Wang, S.4    Liu, Y.5    Rao, M.6    Hoke, A.7
  • 54
    • 84919348531 scopus 로고    scopus 로고
    • Enhancing human nucleus pulposus cells for biological treatment approaches of degenerative intervertebral disc diseases: a systematic review
    • in press. doi:10.1002/term.1583
    • Mern DS, Beierfuß A, Thomé C, Hegewald AA. Enhancing human nucleus pulposus cells for biological treatment approaches of degenerative intervertebral disc diseases: a systematic review. J Tissue Eng Regen Med in press. doi:10.1002/term.1583.
    • J Tissue Eng Regen Med
    • Mern, D.S.1    Beierfuß, A.2    Thomé, C.3    Hegewald, A.A.4
  • 55
    • 14044269226 scopus 로고    scopus 로고
    • Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy
    • Risbud M, Albert T, Guttapalli A, Vresilovic E, Hillibrand A, Vaccaro A, Shapiro I. Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy. Spine 2004, 29:2637-2632.
    • (2004) Spine , vol.29 , pp. 2637-12632
    • Risbud, M.1    Albert, T.2    Guttapalli, A.3    Vresilovic, E.4    Hillibrand, A.5    Vaccaro, A.6    Shapiro, I.7
  • 56
    • 77957559989 scopus 로고    scopus 로고
    • Co-culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype
    • Strassburg S, Richardson SM, Freemont AJ, Hoyland JA. Co-culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype. Regen Med 2010, 5:701-711.
    • (2010) Regen Med , vol.5 , pp. 701-711
    • Strassburg, S.1    Richardson, S.M.2    Freemont, A.J.3    Hoyland, J.A.4
  • 57
    • 73349098162 scopus 로고    scopus 로고
    • Human disk cells from degenerated disks and mesenchymal stem cells in co-culture result in increased matrix production
    • Svanvik T, Henriksson H, Karlsson C, Hagman M, Lindahl A, Brisby H. Human disk cells from degenerated disks and mesenchymal stem cells in co-culture result in increased matrix production. Cells Tissues Organs 2011, 191:2-11.
    • (2011) Cells Tissues Organs , vol.191 , pp. 2-11
    • Svanvik, T.1    Henriksson, H.2    Karlsson, C.3    Hagman, M.4    Lindahl, A.5    Brisby, H.6
  • 58
    • 79957658251 scopus 로고    scopus 로고
    • Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells
    • Purmessur D, Schek R, Abbott R, Ballif B, Godburn K, Iatridis J. Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells. Arthritis Res Ther 2011, 13:R81.
    • (2011) Arthritis Res Ther , vol.13
    • Purmessur, D.1    Schek, R.2    Abbott, R.3    Ballif, B.4    Godburn, K.5    Iatridis, J.6
  • 61
    • 84873410523 scopus 로고    scopus 로고
    • Intervertebral disc-derived stem cells: implications for regenerative medicine and neural repair
    • Erwin M, Islam D, Eftekarpour E, Inman R, Karim M, Fehlings M. Intervertebral disc-derived stem cells: implications for regenerative medicine and neural repair. Spine 2013, 38:211-216.
    • (2013) Spine , vol.38 , pp. 211-216
    • Erwin, M.1    Islam, D.2    Eftekarpour, E.3    Inman, R.4    Karim, M.5    Fehlings, M.6
  • 62
    • 70450270932 scopus 로고    scopus 로고
    • Disc cell clusters in pathological human intervertebral discs are associated with increased stress protein immunostaining
    • Sharp C, Roberts S, Evans H, Brown S. Disc cell clusters in pathological human intervertebral discs are associated with increased stress protein immunostaining. Eur Spine J 2009, 18:1587-1594.
    • (2009) Eur Spine J , vol.18 , pp. 1587-1594
    • Sharp, C.1    Roberts, S.2    Evans, H.3    Brown, S.4
  • 63
    • 0033540274 scopus 로고    scopus 로고
    • Notochordal cells interact with nucleus pulposus cells: regulation of proteoglycan synthesis
    • Aguiar DJ, Johnson SL, Oegema TR. Notochordal cells interact with nucleus pulposus cells: regulation of proteoglycan synthesis. Exp Cell Res 1999, 246:129-137.
    • (1999) Exp Cell Res , vol.246 , pp. 129-137
    • Aguiar, D.J.1    Johnson, S.L.2    Oegema, T.R.3
  • 64
    • 0032011376 scopus 로고    scopus 로고
    • The canine intervertebral disk. Part two: degenerative changes-nonchondrodystrophoid versus chondrodystrophoid disks
    • Bray JP, Burbidge HM. The canine intervertebral disk. Part two: degenerative changes-nonchondrodystrophoid versus chondrodystrophoid disks. J Am Anim Hosp Assoc 1998, 34:135-144.
    • (1998) J Am Anim Hosp Assoc , vol.34 , pp. 135-144
    • Bray, J.P.1    Burbidge, H.M.2
  • 65
    • 0020326310 scopus 로고
    • Ultrastructure of the human intervertebral disc. I. Changes in notochordal cells with age
    • Trout JJ, Buckwalter JA, Moore KC, Landas SK. Ultrastructure of the human intervertebral disc. I. Changes in notochordal cells with age. Tissue Cell 1982, 14:359-369.
    • (1982) Tissue Cell , vol.14 , pp. 359-369
    • Trout, J.J.1    Buckwalter, J.A.2    Moore, K.C.3    Landas, S.K.4
  • 66
    • 77949474632 scopus 로고    scopus 로고
    • Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes
    • Minogue BM, Richardson SM, Zeef LA, Freemont AJ, Hoyland JA. Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes. Arthritis Res Ther 2010, 12:R22.
    • (2010) Arthritis Res Ther , vol.12
    • Minogue, B.M.1    Richardson, S.M.2    Zeef, L.A.3    Freemont, A.J.4    Hoyland, J.A.5
  • 68
    • 79960846930 scopus 로고    scopus 로고
    • Spheroid formation of mesenchymal stem cells on chitosan and chitosan-hyaluronan membranes
    • Huang GS, Dai LG, Yen BL, Hsu SH. Spheroid formation of mesenchymal stem cells on chitosan and chitosan-hyaluronan membranes. Biomaterials 2011, 32:6929-6945.
    • (2011) Biomaterials , vol.32 , pp. 6929-6945
    • Huang, G.S.1    Dai, L.G.2    Yen, B.L.3    Hsu, S.H.4
  • 70
    • 33746682471 scopus 로고    scopus 로고
    • The chondrocyte: biology and clinical application
    • Lin Z, Willers C, Xu J, Zheng MH. The chondrocyte: biology and clinical application. Tissue Eng 2006, 12:1971-1984.
    • (2006) Tissue Eng , vol.12 , pp. 1971-1984
    • Lin, Z.1    Willers, C.2    Xu, J.3    Zheng, M.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.