In vitro system using human neurons demonstrates that varicella-zoster vaccine virus is impaired for reactivation, but not latency

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 17, 2016, Pages E2403-E2412

  Sadaoka, Tomohiko ^a,d   Depledge, Daniel P ^b   Rajbhandari, Labchan ^c   Venkatesan, Arun ^c   Breuer, Judith ^b   Cohen, Jeffrey I ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Herpesvirus; Latency; Reactivation; Varicella vaccine; Varicella zoster virus

Indexed keywords

NEUROTROPHIN; VARICELLA ZOSTER VACCINE;

ARTICLE; HUMAN; HUMAN CELL; HUMAN EMBRYONIC STEM CELL; IN VITRO STUDY; IN VIVO STUDY; NEURAL STEM CELL; PERSISTENT INFECTION; PRIORITY JOURNAL; VARICELLA ZOSTER VIRUS; VIRUS GENOME; VIRUS INFECTION; VIRUS INFECTIVITY; VIRUS REACTIVATION; VIRUS TRANSCRIPTION; CELL CULTURE; FLUORESCENT ANTIBODY TECHNIQUE; HERPES ZOSTER; MICROFLUIDICS; PHYSIOLOGY; VIROLOGY; VIRUS ACTIVATION; VIRUS LATENCY;

CELLS, CULTURED; FLUORESCENT ANTIBODY TECHNIQUE; HERPES ZOSTER; HERPES ZOSTER VACCINE; HERPESVIRUS 3, HUMAN; HUMANS; IN VITRO TECHNIQUES; MICROFLUIDICS; NEURAL STEM CELLS; VIRUS ACTIVATION; VIRUS LATENCY;

EID: 84964725818     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1522575113     Document Type: Article

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