Nuclear factor κB-inducing kinase activation as a mechanism of pancreatic β cell failure in obesity

Journal of Experimental Medicine

Volumn 212, Issue 8, 2015, Pages 1239-1254

  Malle, Elisabeth K ^a   Zammit, Nathan W ^a   Walters, Stacey N ^a   Koay, Yen Chin ^b   Wu, Jianmin ^a,b   Tan, Bernice M ^a   Villanueva, Jeanette E ^a   Brink, Robert ^a,b   Loudovaris, Tom ^c   Cantley, James ^d   McAlpine, Shelli R ^b   Hesselson, Daniel ^a   Grey, Shane T ^a  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NF KAPPA B INDUCING KINASE; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN P100; PROTEIN P52; TRANSCRIPTION FACTOR RELB; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; UNCLASSIFIED DRUG; INSULIN; NF-KAPPA B KINASE; PRIMER DNA; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; DIET INDUCED OBESITY; GENOME-WIDE ASSOCIATION STUDY; GLUCOSE HOMEOSTASIS; HUMAN; HUMAN CELL; HYPOTHALAMUS; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; ZEBRA FISH; ANIMAL; C57BL MOUSE; ENZYMOLOGY; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; MOUSE MUTANT; OBESITY; PATHOLOGY; PHYSIOLOGY; SECRETION (PROCESS); SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; DNA PRIMERS; HUMANS; IMMUNOHISTOCHEMISTRY; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, INBRED C57BL; MICE, OBESE; OBESITY; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; ZEBRAFISH;

EID: 84964697787     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20150218     Document Type: Article

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