-
1
-
-
69949102359
-
Clinical results of treating type 2 diabetic patients with sitagliptin, vildagliptin or saxagliptin-diabetes control and potential adverse events
-
Ahren B. Clinical results of treating type 2 diabetic patients with sitagliptin, vildagliptin or saxagliptin-diabetes control and potential adverse events. Best Pract Res Clin Endocrinol Metab 23: 487-498, 2009.
-
(2009)
Best Pract Res Clin Endocrinol Metab
, vol.23
, pp. 487-498
-
-
Ahren, B.1
-
2
-
-
84869238002
-
DPP-4 inhibition on top of angiotensin receptor blockade offers a new therapeutic approach for diabetic nephropathy
-
Alter ML, Ott IM, von Websky K, Tsuprykov O, Sharkovska Y, Krause-Relle K, Raila J, Henze A, Klein T, Hocher B. DPP-4 inhibition on top of angiotensin receptor blockade offers a new therapeutic approach for diabetic nephropathy. Kidney Blood Press Res 36: 119-130, 2012.
-
(2012)
Kidney Blood Press Res
, vol.36
, pp. 119-130
-
-
Alter, M.L.1
Ott, I.M.2
von Websky, K.3
Tsuprykov, O.4
Sharkovska, Y.5
Krause-Relle, K.6
Raila, J.7
Henze, A.8
Klein, T.9
Hocher, B.10
-
3
-
-
34447267513
-
Efficacy and safety of incretin therapy in type 2 diabetes: Systematic review and meta-analysis
-
Amori RE, Lau J, Pittas AG. Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis. JAMA 298: 194-206, 2007.
-
(2007)
JAMA
, vol.298
, pp. 194-206
-
-
Amori, R.E.1
Lau, J.2
Pittas, A.G.3
-
4
-
-
79951884751
-
Glucagon-like peptide-1-based therapies and cardiovascular disease: Looking beyond glycaemic control
-
Anagnostis P, Athyros VG, Adamidou F, Panagiotou A, Kita M, Karagiannis A, Mikhailidis DP. Glucagon-like peptide-1-based therapies and cardiovascular disease: looking beyond glycaemic control. Diabetes Obes Metab 13: 302-312, 2011.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 302-312
-
-
Anagnostis, P.1
Athyros, V.G.2
Adamidou, F.3
Panagiotou, A.4
Kita, M.5
Karagiannis, A.6
Mikhailidis, D.P.7
-
5
-
-
84896545458
-
DPP-4 inhibitors as therapeutic modulators of immune cell function and associated cardiovascular and renal insulin resistance in obesity and diabetes
-
Aroor A, McKarns S, Nistala R, Demarco V, Gardner M, Garcia-Touza M, Whaley-Connell A, Sowers JR. DPP-4 inhibitors as therapeutic modulators of immune cell function and associated cardiovascular and renal insulin resistance in obesity and diabetes. Cardiorenal Med 3: 48-56, 2013.
-
(2013)
Cardiorenal Med
, vol.3
, pp. 48-56
-
-
Aroor, A.1
McKarns, S.2
Nistala, R.3
Demarco, V.4
Gardner, M.5
Garcia-Touza, M.6
Whaley-Connell, A.7
Sowers, J.R.8
-
6
-
-
84898005689
-
The role of tissue renin-angiotensin-aldosterone system in the development of endothelial dysfunction and arterial stiffness
-
Aroor AA, DeMarco VG, Jia G, Sun Z, Nistala R, Meininger GA, Sowers JR. The role of tissue renin-angiotensin-aldosterone system in the development of endothelial dysfunction and arterial stiffness. Front Endocrinol (Lausanne) 4: 161, 2013.
-
(2013)
Front Endocrinol (Lausanne)
, vol.4
, pp. 161
-
-
Aroor, A.A.1
DeMarco, V.G.2
Jia, G.3
Sun, Z.4
Nistala, R.5
Meininger, G.A.6
Sowers, J.R.7
-
7
-
-
84866613448
-
Mitochondria and oxidative stress in the cardiorenal metabolic syndrome
-
Aroor AR, Mandavia C, Ren J, Sowers JR, Pulakat L. Mitochondria and oxidative stress in the cardiorenal metabolic syndrome. Cardiorenal Med 2: 87-109, 2012.
-
(2012)
Cardiorenal Med
, vol.2
, pp. 87-109
-
-
Aroor, A.R.1
Mandavia, C.2
Ren, J.3
Sowers, J.R.4
Pulakat, L.5
-
8
-
-
84886400216
-
Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance
-
Aroor AR, McKarns S, Demarco VG, Jia G, Sowers JR. Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance. Metabolism 62: 1543-1552, 2013.
-
(2013)
Metabolism
, vol.62
, pp. 1543-1552
-
-
Aroor, A.R.1
McKarns, S.2
Demarco, V.G.3
Jia, G.4
Sowers, J.R.5
-
9
-
-
84879324265
-
Dipeptidylpeptidase inhibition is associated with improvement in blood pressure and diastolic function in insulin resistant male zucker obese rats
-
Aroor AR, Sowers JR, Bender SB, Nistala R, Garro M, Mugerfeld I, Hayden MR, Johnson MS, Salam M, Whaley-Connell A, Demarco VG. Dipeptidylpeptidase inhibition is associated with improvement in blood pressure and diastolic function in insulin resistant male zucker obese rats. Endocrinology 154: 2501-2513, 2013.
-
(2013)
Endocrinology
, vol.154
, pp. 2501-2513
-
-
Aroor, A.R.1
Sowers, J.R.2
Bender, S.B.3
Nistala, R.4
Garro, M.5
Mugerfeld, I.6
Hayden, M.R.7
Johnson, M.S.8
Salam, M.9
Whaley-Connell, A.10
Demarco, V.G.11
-
10
-
-
79959788211
-
Endothelial dysfunction in diabetes: The role of reparatory mechanisms
-
Avogaro A, Albiero M, Menegazzo L, de Kreutzenberg S, Fadini GP. Endothelial dysfunction in diabetes: the role of reparatory mechanisms. Diabetes Care 34, Suppl 2: S285-S290, 2011.
-
(2011)
Diabetes Care
, vol.34
, Issue.SUPPL. 2
-
-
Avogaro, A.1
Albiero, M.2
Menegazzo, L.3
de Kreutzenberg, S.4
Fadini, G.P.5
-
11
-
-
84884198401
-
Dipeptidyl peptidase-4 inhibitors attenuate endothelial function as evaluated by flow-mediated vasodilatation in type 2 diabetic patients
-
Ayaori M, Iwakami N, Uto-Kondo H, Sato H, Sasaki M, Komatsu T, Iizuka M, Takiguchi S, Yakushiji E, Nakaya K, Yogo M, Ogura M, Takase B, Murakami T, Ikewaki K. Dipeptidyl peptidase-4 inhibitors attenuate endothelial function as evaluated by flow-mediated vasodilatation in type 2 diabetic patients. J Am Heart Assoc 2: e003277, 2013.
-
(2013)
J Am Heart Assoc
, vol.2
-
-
Ayaori, M.1
Iwakami, N.2
Uto-Kondo, H.3
Sato, H.4
Sasaki, M.5
Komatsu, T.6
Iizuka, M.7
Takiguchi, S.8
Yakushiji, E.9
Nakaya, K.10
Yogo, M.11
Ogura, M.12
Takase, B.13
Murakami, T.14
Ikewaki, K.15
-
12
-
-
79961222810
-
Pharmacology of dipeptidyl peptidase-4 inhibitors: Similarities and differences
-
Baetta R, Corsini A. Pharmacology of dipeptidyl peptidase-4 inhibitors: similarities and differences. Drugs 71: 1441-1467, 2011.
-
(2011)
Drugs
, vol.71
, pp. 1441-1467
-
-
Baetta, R.1
Corsini, A.2
-
13
-
-
84879258494
-
Cardiovascular pleiotropic actions of DPP-4 inhibitors: A step at the cutting edge in understanding their additional therapeutic potentials
-
Balakumar P, Dhanaraj SA. Cardiovascular pleiotropic actions of DPP-4 inhibitors: a step at the cutting edge in understanding their additional therapeutic potentials. Cell Signal 25: 1799-1803, 2013.
-
(2013)
Cell Signal
, vol.25
, pp. 1799-1803
-
-
Balakumar, P.1
Dhanaraj, S.A.2
-
14
-
-
77950267745
-
Glucagon-like peptide (GLP)-1(9-36)amidemediated cytoprotection is blocked by exendin(9-39) yet does not require the known GLP-1 receptor
-
Ban K, Kim KH, Cho CK, Sauve M, Diamandis EP, Backx PH, Drucker DJ, Husain M. Glucagon-like peptide (GLP)-1(9-36)amidemediated cytoprotection is blocked by exendin(9-39) yet does not require the known GLP-1 receptor. Endocrinology 151: 1520-1531, 2010.
-
(2010)
Endocrinology
, vol.151
, pp. 1520-1531
-
-
Ban, K.1
Kim, K.H.2
Cho, C.K.3
Sauve, M.4
Diamandis, E.P.5
Backx, P.H.6
Drucker, D.J.7
Husain, M.8
-
15
-
-
43249089631
-
Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptordependent and-independent pathways
-
Ban K, Noyan-Ashraf MH, Hoefer J, Bolz SS, Drucker DJ, Husain M. Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptordependent and-independent pathways. Circulation 117: 2340-2350, 2008.
-
(2008)
Circulation
, vol.117
, pp. 2340-2350
-
-
Ban, K.1
Noyan-Ashraf, M.H.2
Hoefer, J.3
Bolz, S.S.4
Drucker, D.J.5
Husain, M.6
-
16
-
-
0034642525
-
Regulation of CD26/DPPIV gene expression by interferons and retinoic acid in tumor B cells
-
Bauvois B, Djavaheri-Mergny M, Rouillard D, Dumont J, Wietzerbin J. Regulation of CD26/DPPIV gene expression by interferons and retinoic acid in tumor B cells. Oncogene 19: 265-272, 2000.
-
(2000)
Oncogene
, vol.19
, pp. 265-272
-
-
Bauvois, B.1
Djavaheri-Mergny, M.2
Rouillard, D.3
Dumont, J.4
Wietzerbin, J.5
-
17
-
-
84873027749
-
Mineralocorticoid receptor-mediated vascular insulin resistance: An early contributor to diabetes-related vascular disease?
-
Bender SB, McGraw AP, Jaffe IZ, Sowers JR. Mineralocorticoid receptor-mediated vascular insulin resistance: an early contributor to diabetes-related vascular disease? Diabetes 62: 313-319, 2013.
-
(2013)
Diabetes
, vol.62
, pp. 313-319
-
-
Bender, S.B.1
McGraw, A.P.2
Jaffe, I.Z.3
Sowers, J.R.4
-
18
-
-
34548545405
-
Myocardial ischaemiareperfusion injury is attenuated by intact glucagon like peptide-1 (GLP-1) in the in vitro rat heart and may involve the p70s6K pathway
-
Bose AK, Mocanu MM, Carr RD, Yellon DM. Myocardial ischaemiareperfusion injury is attenuated by intact glucagon like peptide-1 (GLP-1) in the in vitro rat heart and may involve the p70s6K pathway. Cardiovasc Drugs Ther 21: 253-256, 2007.
-
(2007)
Cardiovasc Drugs Ther
, vol.21
, pp. 253-256
-
-
Bose, A.K.1
Mocanu, M.M.2
Carr, R.D.3
Yellon, D.M.4
-
19
-
-
79955655605
-
The effect of glucagon-like peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients
-
Bremholm L, Hornum M, Andersen UB, Hartmann B, Holst JJ, Jeppesen PB. The effect of glucagon-like peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients. Regul Pept 168: 32-38, 2011.
-
(2011)
Regul Pept
, vol.168
, pp. 32-38
-
-
Bremholm, L.1
Hornum, M.2
Andersen, U.B.3
Hartmann, B.4
Holst, J.J.5
Jeppesen, P.B.6
-
20
-
-
71349084062
-
The effect of glucagon-like peptide-2 on arterial blood flow and cardiac parameters
-
Bremholm L, Hornum M, Andersen UB, Holst JJ. The effect of glucagon-like peptide-2 on arterial blood flow and cardiac parameters. Regul Pept 159: 67-71, 2010.
-
(2010)
Regul Pept
, vol.159
, pp. 67-71
-
-
Bremholm, L.1
Hornum, M.2
Andersen, U.B.3
Holst, J.J.4
-
21
-
-
82955195404
-
Repeated administration of exendin-4 reduces focal cerebral ischemia-induced infarction in rats
-
Briyal S, Gulati K, Gulati A. Repeated administration of exendin-4 reduces focal cerebral ischemia-induced infarction in rats. Brain Res 1427: 23-34, 2012.
-
(2012)
Brain Res
, vol.1427
, pp. 23-34
-
-
Briyal, S.1
Gulati, K.2
Gulati, A.3
-
22
-
-
84859971743
-
Cardiovascular effects of antidiabetic agents: Focus on blood pressure effects of incretin-based therapies
-
Brown NJ. Cardiovascular effects of antidiabetic agents: focus on blood pressure effects of incretin-based therapies. J Am Soc Hypertens 6: 163-168, 2012.
-
(2012)
J Am Soc Hypertens
, vol.6
, pp. 163-168
-
-
Brown, N.J.1
-
23
-
-
0023950461
-
Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications
-
Brownlee M, Cerami A, Vlassara H. Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. N Engl J Med 318: 1315-1321, 1988.
-
(1988)
N Engl J Med
, vol.318
, pp. 1315-1321
-
-
Brownlee, M.1
Cerami, A.2
Vlassara, H.3
-
24
-
-
84900796570
-
GLP-1-based strategies: A physiological analysis of differential mode of action
-
Burcelin R, Gourdy P, Dalle S. GLP-1-based strategies: a physiological analysis of differential mode of action. Physiology (Bethesda) 29: 108-121, 2014.
-
(2014)
Physiology (Bethesda)
, vol.29
, pp. 108-121
-
-
Burcelin, R.1
Gourdy, P.2
Dalle, S.3
-
25
-
-
84888120953
-
Glucagon-like peptide-1 (GLP-1) and its split products GLP-1(9-37) and GLP-1(28-37) stabilize atherosclerotic lesions in apoe-/-mice
-
Burgmaier M, Liberman A, Möllmann J, Kahles F, Reith S, Lebherz C, Marx N, Lehrke M. Glucagon-like peptide-1 (GLP-1) and its split products GLP-1(9-37) and GLP-1(28-37) stabilize atherosclerotic lesions in apoe-/-mice. Atherosclerosis 231: 427-435, 2013.
-
(2013)
Atherosclerosis
, vol.231
, pp. 427-435
-
-
Burgmaier, M.1
Liberman, A.2
Möllmann, J.3
Kahles, F.4
Reith, S.5
Lebherz, C.6
Marx, N.7
Lehrke, M.8
-
26
-
-
84878185729
-
A critical analysis of the clinical use of incretin-based therapies: Are the GLP-1 therapies safe?
-
Butler PC, Elashoff M, Elashoff R, Gale EA. A critical analysis of the clinical use of incretin-based therapies: are the GLP-1 therapies safe? Diabetes Care 36: 2118-2125, 2013.
-
(2013)
Diabetes Care
, vol.36
, pp. 2118-2125
-
-
Butler, P.C.1
Elashoff, M.2
Elashoff, R.3
Gale, E.A.4
-
27
-
-
57049146797
-
Oxidative stress and inflammation, a link between chronic kidney disease and cardiovascular disease
-
Cachofeiro V, Goicochea M, de Vinuesa SG, Oubina P, Lahera V, Luno J. Oxidative stress and inflammation, a link between chronic kidney disease and cardiovascular disease. Kidney Int Suppl 111: S4-S9, 2008.
-
(2008)
Kidney Int Suppl
, vol.111
-
-
Cachofeiro, V.1
Goicochea, M.2
de Vinuesa, S.G.3
Oubina, P.4
Lahera, V.5
Luno, J.6
-
28
-
-
84884250098
-
Beyond glycemic control in diabetes mellitus: Effects of incretin-based therapies on bone metabolism
-
Ceccarelli E, Guarino EG, Merlotti D, Patti A, Gennari L, Nuti R, Dotta F. Beyond glycemic control in diabetes mellitus: effects of incretin-based therapies on bone metabolism. Front Endocrinol (Lausanne) 4: 73, 2013.
-
(2013)
Front Endocrinol (Lausanne)
, vol.4
, pp. 73
-
-
Ceccarelli, E.1
Guarino, E.G.2
Merlotti, D.3
Patti, A.4
Gennari, L.5
Nuti, R.6
Dotta, F.7
-
29
-
-
84859529626
-
Glucagon-like peptide 1 recruits microvasculature and increases glucose use in muscle via a nitric oxide-dependent mechanism
-
Chai W, Dong Z, Wang N, Wang W, Tao L, Cao W, Liu Z. Glucagon-like peptide 1 recruits microvasculature and increases glucose use in muscle via a nitric oxide-dependent mechanism. Diabetes 61: 888-896, 2012.
-
(2012)
Diabetes
, vol.61
, pp. 888-896
-
-
Chai, W.1
Dong, Z.2
Wang, N.3
Wang, W.4
Tao, L.5
Cao, W.6
Liu, Z.7
-
30
-
-
61949318555
-
Proinflammatory phenotype of perivascular adipocytes: Influence of high-fat feeding
-
Chatterjee TK, Stoll LL, Denning GM, Harrelson A, Blomkalns AL, Idelman G, Rothenberg FG, Neltner B, Romig-Martin SA, Dickson EW, Rudich S, Weintraub NL. Proinflammatory phenotype of perivascular adipocytes: influence of high-fat feeding. Circ Res 104: 541-549, 2009.
-
(2009)
Circ Res
, vol.104
, pp. 541-549
-
-
Chatterjee, T.K.1
Stoll, L.L.2
Denning, G.M.3
Harrelson, A.4
Blomkalns, A.L.5
Idelman, G.6
Rothenberg, F.G.7
Neltner, B.8
Romig-Martin, S.A.9
Dickson, E.W.10
Rudich, S.11
Weintraub, N.L.12
-
31
-
-
84894374325
-
MMP-9 inhibition: A therapeutic strategy in ischemic stroke
-
Chaturvedi M, Kaczmarek L. MMP-9 inhibition: a therapeutic strategy in ischemic stroke. Mol Neurobiol 49: 563-573, 2014.
-
(2014)
Mol Neurobiol
, vol.49
, pp. 563-573
-
-
Chaturvedi, M.1
Kaczmarek, L.2
-
32
-
-
84896709475
-
Uric acid-key ingredient in the recipe for cardiorenal metabolic syndrome
-
Chaudhary K, Kunal M, Sowers J, Aroor A. Uric acid-key ingredient in the recipe for cardiorenal metabolic syndrome. Cardiorenal Med 3: 208-220, 2013.
-
(2013)
Cardiorenal Med
, vol.3
, pp. 208-220
-
-
Chaudhary, K.1
Kunal, M.2
Sowers, J.3
Aroor, A.4
-
33
-
-
84885662277
-
Effects of telmisartan and linagliptin when used in combination on blood pressure and oxidative stress in rats with 2-kidney-1-clip hypertension
-
Chaykovska L, Alter ML, von Websky K, Hohmann M, Tsuprykov O, Reichetzeder C, Kutil B, Kraft R, Klein T, Hocher B. Effects of telmisartan and linagliptin when used in combination on blood pressure and oxidative stress in rats with 2-kidney-1-clip hypertension. J Hypertens 31: 2290-2299, 2013.
-
(2013)
J Hypertens
, vol.31
, pp. 2290-2299
-
-
Chaykovska, L.1
Alter, M.L.2
von Websky, K.3
Hohmann, M.4
Tsuprykov, O.5
Reichetzeder, C.6
Kutil, B.7
Kraft, R.8
Klein, T.9
Hocher, B.10
-
34
-
-
81355124070
-
Effects of DPP-4 inhibitors on the heart in a rat model of uremic cardiomyopathy
-
Chaykovska L, von Websky K, Rahnenfuhrer J, Alter M, Heiden S, Fuchs H, Runge F, Klein T, Hocher B. Effects of DPP-4 inhibitors on the heart in a rat model of uremic cardiomyopathy. PLoS One 6: e27861, 2011.
-
(2011)
PLoS One
, vol.6
-
-
Chaykovska, L.1
von Websky, K.2
Rahnenfuhrer, J.3
Alter, M.4
Heiden, S.5
Fuchs, H.6
Runge, F.7
Klein, T.8
Hocher, B.9
-
35
-
-
84855770694
-
Saxagliptin for the treatment of type 2 diabetes mellitus: Assessing cardiovascular data
-
Cobble ME, Frederich R. Saxagliptin for the treatment of type 2 diabetes mellitus: assessing cardiovascular data. Cardiovasc Diabetol 11: 6, 2012.
-
(2012)
Cardiovasc Diabetol
, vol.11
, pp. 6
-
-
Cobble, M.E.1
Frederich, R.2
-
36
-
-
84883781630
-
DPP-4 inhibition attenuates cardiac dysfunction and adverse remodeling following myocardial infarction in rats with experimental diabetes
-
Connelly KA, Zhang Y, Advani A, Advani SL, Thai K, Yuen DA, Gilbert RE. DPP-4 inhibition attenuates cardiac dysfunction and adverse remodeling following myocardial infarction in rats with experimental diabetes. Cardiovasc Ther 31: 259-267, 2013.
-
(2013)
Cardiovasc Ther
, vol.31
, pp. 259-267
-
-
Connelly, K.A.1
Zhang, Y.2
Advani, A.3
Advani, S.L.4
Thai, K.5
Yuen, D.A.6
Gilbert, R.E.7
-
37
-
-
70349774693
-
On the origin of serum CD26 and its altered concentration in cancer patients
-
Cordero OJ, Salgado FJ, Nogueira M. On the origin of serum CD26 and its altered concentration in cancer patients. Cancer Immunol Immunother 58: 1723-1747, 2009.
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 1723-1747
-
-
Cordero, O.J.1
Salgado, F.J.2
Nogueira, M.3
-
38
-
-
79961180020
-
Mechanisms mediating the diuretic and natriuretic actions of the incretin hormone glucagon-like peptide-1
-
Crajoinas RO, Oricchio FT, Pessoa TD, Pacheco BP, Lessa LM, Malnic G, Girardi AC. Mechanisms mediating the diuretic and natriuretic actions of the incretin hormone glucagon-like peptide-1. Am J Physiol Renal Physiol 301: F355-F363, 2011.
-
(2011)
Am J Physiol Renal Physiol
, vol.301
-
-
Crajoinas, R.O.1
Oricchio, F.T.2
Pessoa, T.D.3
Pacheco, B.P.4
Lessa, L.M.5
Malnic, G.6
Girardi, A.C.7
-
39
-
-
84858722980
-
Glucagon-like peptide-1 receptor activation reduces ischaemic brain damage following stroke in Type 2 diabetic rats
-
Darsalia V, Mansouri S, Ortsater H, Olverling A, Nozadze N, Kappe C, Iverfeldt K, Tracy LM, Grankvist N, Sjoholm A, Patrone C. Glucagon-like peptide-1 receptor activation reduces ischaemic brain damage following stroke in Type 2 diabetic rats. Clin Sci (Lond) 122: 473-483, 2012.
-
(2012)
Clin Sci (Lond)
, vol.122
, pp. 473-483
-
-
Darsalia, V.1
Mansouri, S.2
Ortsater, H.3
Olverling, A.4
Nozadze, N.5
Kappe, C.6
Iverfeldt, K.7
Tracy, L.M.8
Grankvist, N.9
Sjoholm, A.10
Patrone, C.11
-
40
-
-
84875438002
-
The DPP-4 inhibitor linagliptin counteracts stroke in the normal and diabetic mouse brain: A comparison with glimepiride
-
Darsalia V, Ortsater H, Olverling A, Darlof E, Wolbert P, Nystrom T, Klein T, Sjoholm A, Patrone C. The DPP-4 inhibitor linagliptin counteracts stroke in the normal and diabetic mouse brain: a comparison with glimepiride. Diabetes 62: 1289-1296, 2012.
-
(2012)
Diabetes
, vol.62
, pp. 1289-1296
-
-
Darsalia, V.1
Ortsater, H.2
Olverling, A.3
Darlof, E.4
Wolbert, P.5
Nystrom, T.6
Klein, T.7
Sjoholm, A.8
Patrone, C.9
-
41
-
-
77955980990
-
Reactive oxygen species, NADPH oxidases, and hypertension
-
Datla SR, Griendling KK. Reactive oxygen species, NADPH oxidases, and hypertension. Hypertension 56: 325-330, 2010.
-
(2010)
Hypertension
, vol.56
, pp. 325-330
-
-
Datla, S.R.1
Griendling, K.K.2
-
42
-
-
0028953577
-
Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo
-
Deacon CF, Johnsen AH, Holst JJ. Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo. J Clin Endocrinol Metab 80: 952-957, 1995.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 952-957
-
-
Deacon, C.F.1
Johnsen, A.H.2
Holst, J.J.3
-
43
-
-
78851472527
-
Effect of linagliptin monotherapy on glycaemic control and markers of beta-cell function in patients with inadequately controlled type 2 diabetes: A randomized controlled trial
-
Del Prato S, Barnett AH, Huisman H, Neubacher D, Woerle HJ, Dugi KA. Effect of linagliptin monotherapy on glycaemic control and markers of beta-cell function in patients with inadequately controlled type 2 diabetes: a randomized controlled trial. Diabetes Obes Metab 13: 258-267, 2011.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 258-267
-
-
Del Prato, S.1
Barnett, A.H.2
Huisman, H.3
Neubacher, D.4
Woerle, H.J.5
Dugi, K.A.6
-
44
-
-
84883802810
-
Does drug therapy reverse endothelial progenitor cell dysfunction in diabetes?
-
Desouza CV. Does drug therapy reverse endothelial progenitor cell dysfunction in diabetes? J Diabetes Complications 27: 519-525, 2013.
-
(2013)
J Diabetes Complications
, vol.27
, pp. 519-525
-
-
Desouza, C.V.1
-
45
-
-
84885844459
-
Circulating dipeptidyl peptidase iv activity correlates with cardiac dysfunction in human and experimental heart failure
-
Dos Santos L, Salles TA, Arruda-Junior DF, Campos LC, Pereira AC, Barreto AL, Antonio EL, Mansur AJ, Tucci PJ, Krieger JE, Girardi AC. Circulating dipeptidyl peptidase iv activity correlates with cardiac dysfunction in human and experimental heart failure. Circ Heart Fail 6: 1029-1038, 2013.
-
(2013)
Circ Heart Fail
, vol.6
, pp. 1029-1038
-
-
Dos Santos, L.1
Salles, T.A.2
Arruda-Junior, D.F.3
Campos, L.C.4
Pereira, A.C.5
Barreto, A.L.6
Antonio, E.L.7
Mansur, A.J.8
Tucci, P.J.9
Krieger, J.E.10
Girardi, A.C.11
-
46
-
-
84884583757
-
Incretin action in the pancreas: Potential promise, possible perils, and pathological pitfalls
-
Drucker DJ. Incretin action in the pancreas: potential promise, possible perils, and pathological pitfalls. Diabetes 62: 3316-3323, 2013.
-
(2013)
Diabetes
, vol.62
, pp. 3316-3323
-
-
Drucker, D.J.1
-
47
-
-
33845998516
-
The role of gut hormones in glucose homeostasis
-
Drucker DJ. The role of gut hormones in glucose homeostasis. J Clin Invest 117: 24-32, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 24-32
-
-
Drucker, D.J.1
-
48
-
-
84894207845
-
Physiology and pharmacology of the enteroendocrine hormone glucagon-like peptide-2
-
Drucker DJ, Yusta B. Physiology and pharmacology of the enteroendocrine hormone glucagon-like peptide-2. Annu Rev Physiol 76: 561-583, 2014.
-
(2014)
Annu Rev Physiol
, vol.76
, pp. 561-583
-
-
Drucker, D.J.1
Yusta, B.2
-
49
-
-
79959559653
-
Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies
-
Elashoff M, Matveyenko AV, Gier B, Elashoff R, Butler PC. Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies. Gastroenterology 141: 150-156, 2011.
-
(2011)
Gastroenterology
, vol.141
, pp. 150-156
-
-
Elashoff, M.1
Matveyenko, A.V.2
Gier, B.3
Elashoff, R.4
Butler, P.C.5
-
50
-
-
0033557503
-
Regulation of the gene for human dipeptidyl peptidase IV by hepatocyte nuclear factor 1 alpha
-
Erickson RH, Gum JR, Lotterman CD, Hicks JW, Lai RS, Kim YS. Regulation of the gene for human dipeptidyl peptidase IV by hepatocyte nuclear factor 1 alpha. Biochem J 338: 91-97, 1999.
-
(1999)
Biochem J
, vol.338
, pp. 91-97
-
-
Erickson, R.H.1
Gum, J.R.2
Lotterman, C.D.3
Hicks, J.W.4
Lai, R.S.5
Kim, Y.S.6
-
51
-
-
84874597960
-
Anagliptin, a DPP-4 inhibitor, suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction and attenuates atherosclerosis in male apo E-deficient mice
-
Ervinna N, Mita T, Yasunari E, Azuma K, Tanaka R, Fujimura S, Sukmawati D, Nomiyama T, Kanazawa A, Kawamori R, Fujitani Y, Watada H. Anagliptin, a DPP-4 inhibitor, suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction and attenuates atherosclerosis in male apo E-deficient mice. Endocrinology 154: 1260-1270, 2013.
-
(2013)
Endocrinology
, vol.154
, pp. 1260-1270
-
-
Ervinna, N.1
Mita, T.2
Yasunari, E.3
Azuma, K.4
Tanaka, R.5
Fujimura, S.6
Sukmawati, D.7
Nomiyama, T.8
Kanazawa, A.9
Kawamori, R.10
Fujitani, Y.11
Watada, H.12
-
52
-
-
80051795160
-
Cardiovascular effects of DPP-4 inhibition: Beyond GLP-1
-
Fadini GP, Avogaro A. Cardiovascular effects of DPP-4 inhibition: beyond GLP-1. Vascul Pharmacol 55: 10-16, 2011.
-
(2011)
Vascul Pharmacol
, vol.55
, pp. 10-16
-
-
Fadini, G.P.1
Avogaro, A.2
-
53
-
-
77954182062
-
Potential manipulation of endothelial progenitor cells in diabetes and its complications
-
Fadini GP, Avogaro A. Potential manipulation of endothelial progenitor cells in diabetes and its complications. Diabetes Obes Metab 12: 570-583, 2010.
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 570-583
-
-
Fadini, G.P.1
Avogaro, A.2
-
54
-
-
77958195997
-
The oral dipeptidyl peptidase-4 inhibitor sitagliptin increases circulating endothelial progenitor cells in patients with type 2 diabetes: Possible role of stromal-derived factor-1alpha
-
Fadini GP, Boscaro E, Albiero M, Menegazzo L, Frison V, de Kreutzenberg S, Agostini C, Tiengo A, Avogaro A. The oral dipeptidyl peptidase-4 inhibitor sitagliptin increases circulating endothelial progenitor cells in patients with type 2 diabetes: possible role of stromal-derived factor-1alpha. Diabetes Care 33: 1607-1609, 2010.
-
(2010)
Diabetes Care
, vol.33
, pp. 1607-1609
-
-
Fadini, G.P.1
Boscaro, E.2
Albiero, M.3
Menegazzo, L.4
Frison, V.5
de Kreutzenberg, S.6
Agostini, C.7
Tiengo, A.8
Avogaro, A.9
-
55
-
-
34247635096
-
Significance of endothelial progenitor cells in subjects with diabetes
-
Fadini GP, Sartore S, Agostini C, Avogaro A. Significance of endothelial progenitor cells in subjects with diabetes. Diabetes Care 30: 1305-1313, 2007.
-
(2007)
Diabetes Care
, vol.30
, pp. 1305-1313
-
-
Fadini, G.P.1
Sartore, S.2
Agostini, C.3
Avogaro, A.4
-
56
-
-
77955406467
-
Effects of sitagliptin treatment on dysmetabolism, inflammation, and oxidative stress in an animal model of type 2 diabetes (ZDF rat)
-
Ferreira L, Teixeira-de-Lemos E, Pinto F, Parada B, Mega C, Vala H, Pinto R, Garrido P, Sereno J, Fernandes R, Santos P, Velada I, Melo A, Nunes S, Teixeira F, Reis F. Effects of sitagliptin treatment on dysmetabolism, inflammation, and oxidative stress in an animal model of type 2 diabetes (ZDF rat). Mediators Inflamm 2010: 592760, 2010.
-
(2010)
Mediators Inflamm
, vol.2010
, pp. 592760
-
-
Ferreira, L.1
Teixeira-de-Lemos, E.2
Pinto, F.3
Parada, B.4
Mega, C.5
Vala, H.6
Pinto, R.7
Garrido, P.8
Sereno, J.9
Fernandes, R.10
Santos, P.11
Velada, I.12
Melo, A.13
Nunes, S.14
Teixeira, F.15
Reis, F.16
-
57
-
-
68349148211
-
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
-
Feuerer M, Herrero L, Cipolletta D, Naaz A, Wong J, Nayer A, Lee J, Goldfine AB, Benoist C, Shoelson S, Mathis D. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 15: 930-939, 2009.
-
(2009)
Nat Med
, vol.15
, pp. 930-939
-
-
Feuerer, M.1
Herrero, L.2
Cipolletta, D.3
Naaz, A.4
Wong, J.5
Nayer, A.6
Lee, J.7
Goldfine, A.B.8
Benoist, C.9
Shoelson, S.10
Mathis, D.11
-
58
-
-
84856487711
-
Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010
-
Flegal KM, Carroll MD, Kit BK, Ogden CL. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. JAMA 307: 491-497, 2012.
-
(2012)
JAMA
, vol.307
, pp. 491-497
-
-
Flegal, K.M.1
Carroll, M.D.2
Kit, B.K.3
Ogden, C.L.4
-
59
-
-
77956539705
-
Commentary: What can we learn from the continuing regulatory focus on the thiazolidinediones?
-
Freemantle N. Commentary: What can we learn from the continuing regulatory focus on the thiazolidinediones? BMJ 341: c4812, 2010.
-
(2010)
BMJ
, vol.341
-
-
Freemantle, N.1
-
60
-
-
84904379996
-
Renal impairment has no clinically relevant effect on the long-term exposure of linagliptin in patients with type 2 diabetes
-
Friedrich C, Emser A, Woerle HJ, Graefe-Mody U. Renal impairment has no clinically relevant effect on the long-term exposure of linagliptin in patients with type 2 diabetes. Am J Ther 20: 618-621, 2013.
-
(2013)
Am J Ther
, vol.20
, pp. 618-621
-
-
Friedrich, C.1
Emser, A.2
Woerle, H.J.3
Graefe-Mody, U.4
-
61
-
-
79955438066
-
Telmisartan improves insulin resistance and modulates adipose tissue macrophage polarization in high-fat-fed mice
-
Fujisaka S, Usui I, Kanatani Y, Ikutani M, Takasaki I, Tsuneyama K, Tabuchi Y, Bukhari A, Yamazaki Y, Suzuki H, Senda S, Aminuddin A, Nagai Y, Takatsu K, Kobayashi M, Tobe K. Telmisartan improves insulin resistance and modulates adipose tissue macrophage polarization in high-fat-fed mice. Endocrinology 152: 1789-1799, 2011.
-
(2011)
Endocrinology
, vol.152
, pp. 1789-1799
-
-
Fujisaka, S.1
Usui, I.2
Kanatani, Y.3
Ikutani, M.4
Takasaki, I.5
Tsuneyama, K.6
Tabuchi, Y.7
Bukhari, A.8
Yamazaki, Y.9
Suzuki, H.10
Senda, S.11
Aminuddin, A.12
Nagai, Y.13
Takatsu, K.14
Kobayashi, M.15
Tobe, K.16
-
62
-
-
38949210220
-
Effect of a multifactorial intervention on mortality in type 2 diabetes
-
Gaede P, Lund-Andersen H, Parving HH, Pedersen O. Effect of a multifactorial intervention on mortality in type 2 diabetes. N Engl J Med 358: 580-591, 2008.
-
(2008)
N Engl J Med
, vol.358
, pp. 580-591
-
-
Gaede, P.1
Lund-Andersen, H.2
Parving, H.H.3
Pedersen, O.4
-
63
-
-
84864757433
-
2-year efficacy and safety of linagliptin compared with glimepiride in patients with type 2 diabetes inadequately controlled on metformin: A randomised, double-blind, noninferiority trial
-
Gallwitz B, Rosenstock J, Rauch T, Bhattacharya S, Patel S, von Eynatten M, Dugi KA, Woerle HJ. 2-year efficacy and safety of linagliptin compared with glimepiride in patients with type 2 diabetes inadequately controlled on metformin: a randomised, double-blind, noninferiority trial. Lancet 380: 475-483, 2012.
-
(2012)
Lancet
, vol.380
, pp. 475-483
-
-
Gallwitz, B.1
Rosenstock, J.2
Rauch, T.3
Bhattacharya, S.4
Patel, S.5
von Eynatten, M.6
Dugi, K.A.7
Woerle, H.J.8
-
64
-
-
84914144805
-
A systematic review of acute pancreatitis as an adverse event of type 2 diabetes drugs: From hard facts to a balanced position
-
Giorda CB, Nada E, Tartaglino B, Marafetti L, Gnavi R. A systematic review of acute pancreatitis as an adverse event of type 2 diabetes drugs: from hard facts to a balanced position. Diabetes Obes Metab 2014.
-
(2014)
Diabetes Obes Metab
-
-
Giorda, C.B.1
Nada, E.2
Tartaglino, B.3
Marafetti, L.4
Gnavi, R.5
-
66
-
-
0028867442
-
Distribution of GLP-1 binding sites in the rat brain: Evidence that exendin-4 is a ligand of brain GLP-1 binding sites
-
Goke R, Larsen PJ, Mikkelsen JD, Sheikh SP. Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites. Eur J Neurosci 7: 2294-2300, 1995.
-
(1995)
Eur J Neurosci
, vol.7
, pp. 2294-2300
-
-
Goke, R.1
Larsen, P.J.2
Mikkelsen, J.D.3
Sheikh, S.P.4
-
67
-
-
84863436536
-
Comparative clinical pharmacokinetics of dipeptidyl peptidase-4 inhibitors
-
Golightly LK, Drayna CC, McDermott MT. Comparative clinical pharmacokinetics of dipeptidyl peptidase-4 inhibitors. Clin Pharmacokinet 51: 501-514, 2012.
-
(2012)
Clin Pharmacokinet
, vol.51
, pp. 501-514
-
-
Golightly, L.K.1
Drayna, C.C.2
McDermott, M.T.3
-
68
-
-
80052530183
-
Effect of renal impairment on the pharmacokinetics of the dipeptidyl peptidase-4 inhibitor linagliptin(*)
-
Graefe-Mody U, Friedrich C, Port A, Ring A, Retlich S, Heise T, Halabi A, Woerle HJ. Effect of renal impairment on the pharmacokinetics of the dipeptidyl peptidase-4 inhibitor linagliptin(*). Diabetes Obes Metab 13: 939-946, 2011.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 939-946
-
-
Graefe-Mody, U.1
Friedrich, C.2
Port, A.3
Ring, A.4
Retlich, S.5
Heise, T.6
Halabi, A.7
Woerle, H.J.8
-
69
-
-
84888644874
-
Rationale, design, and organization of a randomized, controlled Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS) in patients with type 2 diabetes and established cardiovascular disease
-
Green JB, Bethel MA, Paul SK, Ring A, Kaufman KD, Shapiro DR, Califf RM, Holman RR. Rationale, design, and organization of a randomized, controlled Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS) in patients with type 2 diabetes and established cardiovascular disease. Am Heart J 166: 983. e7-989. e7, 2013.
-
(2013)
Am Heart J
, vol.166
-
-
Green, J.B.1
Bethel, M.A.2
Paul, S.K.3
Ring, A.4
Kaufman, K.D.5
Shapiro, D.R.6
Califf, R.M.7
Holman, R.R.8
-
70
-
-
84890476805
-
Linagliptin lowers albuminuria on top of recommended standard treatment in patients with type 2 diabetes and renal dysfunction
-
Groop PH, Cooper ME, Perkovic V, Emser A, Woerle HJ, von Eynatten M. Linagliptin lowers albuminuria on top of recommended standard treatment in patients with type 2 diabetes and renal dysfunction. Diabetes Care 36: 3460-3468, 2013.
-
(2013)
Diabetes Care
, vol.36
, pp. 3460-3468
-
-
Groop, P.H.1
Cooper, M.E.2
Perkovic, V.3
Emser, A.4
Woerle, H.J.5
von Eynatten, M.6
-
71
-
-
77949268923
-
Glucagonlike peptide-1 receptor signalling selectively regulates murine lymphocyte proliferation and maintenance of peripheral regulatory T cells
-
Hadjiyanni I, Siminovitch KA, Danska JS, Drucker DJ. Glucagonlike peptide-1 receptor signalling selectively regulates murine lymphocyte proliferation and maintenance of peripheral regulatory T cells. Diabetologia 53: 730-740, 2010.
-
(2010)
Diabetologia
, vol.53
, pp. 730-740
-
-
Hadjiyanni, I.1
Siminovitch, K.A.2
Danska, J.S.3
Drucker, D.J.4
-
72
-
-
69549128161
-
Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system
-
Hamilton A, Holscher C. Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system. Neuroreport 20: 1161-1166, 2009.
-
(2009)
Neuroreport
, vol.20
, pp. 1161-1166
-
-
Hamilton, A.1
Holscher, C.2
-
73
-
-
0033303516
-
Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine
-
Hansen L, Deacon CF, Orskov C, Holst JJ. Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine. Endocrinology 140: 5356-5363, 1999.
-
(1999)
Endocrinology
, vol.140
, pp. 5356-5363
-
-
Hansen, L.1
Deacon, C.F.2
Orskov, C.3
Holst, J.J.4
-
74
-
-
84893498368
-
GLP-2 and mesenteric blood flow
-
Hansen LB. GLP-2 and mesenteric blood flow. Dan Med J 60: B4634, 2013.
-
(2013)
Dan Med J
, vol.60
-
-
Hansen, L.B.1
-
76
-
-
84886875665
-
Dipeptidyl peptidase-4 inhibitors and GLP-1 reduce myocardial infarct size in a glucose-dependent manner
-
Hausenloy DJ, Whittington HJ, Wynne AM, Begum SS, Theodorou L, Riksen N, Mocanu MM, Yellon DM. Dipeptidyl peptidase-4 inhibitors and GLP-1 reduce myocardial infarct size in a glucose-dependent manner. Cardiovasc Diabetol 12: 154, 2013.
-
(2013)
Cardiovasc Diabetol
, vol.12
, pp. 154
-
-
Hausenloy, D.J.1
Whittington, H.J.2
Wynne, A.M.3
Begum, S.S.4
Theodorou, L.5
Riksen, N.6
Mocanu, M.M.7
Yellon, D.M.8
-
77
-
-
84865576863
-
Renal and cardiac effects of DPP-4 Inhibitors-from preclinical development to clinical research
-
Hocher B, Reichetzeder C, Alter ML. Renal and cardiac effects of DPP-4 Inhibitors-from preclinical development to clinical research. Kidney Blood Press Res 36: 65-84, 2012.
-
(2012)
Kidney Blood Press Res
, vol.36
, pp. 65-84
-
-
Hocher, B.1
Reichetzeder, C.2
Alter, M.L.3
-
78
-
-
84878587722
-
The novel DPP-4 inhibitors linagliptin and BI 14361 reduce infarct size after myocardial ischemia/reperfusion in rats
-
Hocher B, Sharkovska Y, Mark M, Klein T, Pfab T. The novel DPP-4 inhibitors linagliptin and BI 14361 reduce infarct size after myocardial ischemia/reperfusion in rats. Int J Cardiol 167: 87-93, 2013.
-
(2013)
Int J Cardiol
, vol.167
, pp. 87-93
-
-
Hocher, B.1
Sharkovska, Y.2
Mark, M.3
Klein, T.4
Pfab, T.5
-
79
-
-
79951626557
-
Neuroprotective properties of GLP-1: Theoretical and practical applications
-
Holst JJ, Burcelin R, Nathanson E. Neuroprotective properties of GLP-1: theoretical and practical applications. Curr Med Res Opin 27: 547-558, 2011.
-
(2011)
Curr Med Res Opin
, vol.27
, pp. 547-558
-
-
Holst, J.J.1
Burcelin, R.2
Nathanson, E.3
-
80
-
-
77949273334
-
The glucagon-like peptide 1 receptor is essential for postprandial lipoprotein synthesis and secretion in hamsters and mice
-
Hsieh J, Longuet C, Baker CL, Qin B, Federico LM, Drucker DJ, Adeli K. The glucagon-like peptide 1 receptor is essential for postprandial lipoprotein synthesis and secretion in hamsters and mice. Diabetologia 53: 552-561, 2010.
-
(2010)
Diabetologia
, vol.53
, pp. 552-561
-
-
Hsieh, J.1
Longuet, C.2
Baker, C.L.3
Qin, B.4
Federico, L.M.5
Drucker, D.J.6
Adeli, K.7
-
81
-
-
84868642036
-
Dipeptidyl peptidase-4 inhibitor improves neovascularization by increasing circulating endothelial progenitor cells
-
Huang CY, Shih CM, Tsao NW, Lin YW, Huang PH, Wu SC, Lee AW, Kao YT, Chang NC, Nakagami H, Morishita R, Ou KL, Hou WC, Lin CY, Shyu KG, Lin FY. Dipeptidyl peptidase-4 inhibitor improves neovascularization by increasing circulating endothelial progenitor cells. Br J Pharmacol 167: 1506-1519, 2012.
-
(2012)
Br J Pharmacol
, vol.167
, pp. 1506-1519
-
-
Huang, C.Y.1
Shih, C.M.2
Tsao, N.W.3
Lin, Y.W.4
Huang, P.H.5
Wu, S.C.6
Lee, A.W.7
Kao, Y.T.8
Chang, N.C.9
Nakagami, H.10
Morishita, R.11
Ou, K.L.12
Hou, W.C.13
Lin, C.Y.14
Shyu, K.G.15
Lin, F.Y.16
-
82
-
-
84858713174
-
Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis
-
Hunter K, Holscher C. Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis. BMC Neurosci 13: 33, 2012.
-
(2012)
BMC Neurosci
, vol.13
, pp. 33
-
-
Hunter, K.1
Holscher, C.2
-
83
-
-
51849103389
-
Safety, tolerability, pharmacokinetics, and pharmacodynamics of single oral doses of BI 1356, an inhibitor of dipeptidyl peptidase 4, in healthy male volunteers
-
Huttner S, Graefe-Mody EU, Withopf B, Ring A, Dugi KA. Safety, tolerability, pharmacokinetics, and pharmacodynamics of single oral doses of BI 1356, an inhibitor of dipeptidyl peptidase 4, in healthy male volunteers. J Clin Pharmacol 48: 1171-1178, 2008.
-
(2008)
J Clin Pharmacol
, vol.48
, pp. 1171-1178
-
-
Huttner, S.1
Graefe-Mody, E.U.2
Withopf, B.3
Ring, A.4
Dugi, K.A.5
-
84
-
-
84883084459
-
Advanced glycation end products evoke endothelial cell damage by stimulating soluble dipeptidyl peptidase-4 production and its interaction with mannose 6-phosphate/insulin-like growth factor II receptor
-
Ishibashi Y, Matsui T, Maeda S, Higashimoto Y, Yamagishi S. Advanced glycation end products evoke endothelial cell damage by stimulating soluble dipeptidyl peptidase-4 production and its interaction with mannose 6-phosphate/insulin-like growth factor II receptor. Cardiovasc Diabetol 12: 125, 2013.
-
(2013)
Cardiovasc Diabetol
, vol.12
, pp. 125
-
-
Ishibashi, Y.1
Matsui, T.2
Maeda, S.3
Higashimoto, Y.4
Yamagishi, S.5
-
85
-
-
73949118948
-
Glucagon-like peptide-1 (GLP-1) inhibits advanced glycation end product (AGE)-induced up-regulation of VCAM-1 mRNA levels in endothelial cells by suppressing AGE receptor (RAGE) expression
-
Ishibashi Y, Matsui T, Takeuchi M, Yamagishi S. Glucagon-like peptide-1 (GLP-1) inhibits advanced glycation end product (AGE)-induced up-regulation of VCAM-1 mRNA levels in endothelial cells by suppressing AGE receptor (RAGE) expression. Biochem Biophys Res Commun 391: 1405-1408, 2010.
-
(2010)
Biochem Biophys Res Commun
, vol.391
, pp. 1405-1408
-
-
Ishibashi, Y.1
Matsui, T.2
Takeuchi, M.3
Yamagishi, S.4
-
86
-
-
77957221733
-
Dipeptidyl peptidase IV inhibition alters the hemodynamic response to angiotensin-converting enzyme inhibition in humans with the metabolic syndrome
-
Jackson EK. Dipeptidyl peptidase IV inhibition alters the hemodynamic response to angiotensin-converting enzyme inhibition in humans with the metabolic syndrome. Hypertension 56: 581-583, 2010.
-
(2010)
Hypertension
, vol.56
, pp. 581-583
-
-
Jackson, E.K.1
-
87
-
-
45849115827
-
Sitagliptin augments sympathetic enhancement of the renovascular effects of angiotensin II in genetic hypertension
-
Jackson EK, Mi Z. Sitagliptin augments sympathetic enhancement of the renovascular effects of angiotensin II in genetic hypertension. Hypertension 51: 1637-1642, 2008.
-
(2008)
Hypertension
, vol.51
, pp. 1637-1642
-
-
Jackson, E.K.1
Mi, Z.2
-
88
-
-
79251589063
-
Elevated proinflammatory cytokine production by a skewed T cell compartment requires monocytes and promotes inflammation in type 2 diabetes
-
Jagannathan-Bogdan M, McDonnell ME, Shin H, Rehman Q, Hasturk H, Apovian CM, Nikolajczyk BS. Elevated proinflammatory cytokine production by a skewed T cell compartment requires monocytes and promotes inflammation in type 2 diabetes. J Immunol 186: 1162-1172, 2011.
-
(2011)
J Immunol
, vol.186
, pp. 1162-1172
-
-
Jagannathan-Bogdan, M.1
McDonnell, M.E.2
Shin, H.3
Rehman, Q.4
Hasturk, H.5
Apovian, C.M.6
Nikolajczyk, B.S.7
-
89
-
-
67049168044
-
Treatment of patients with diabetes with GLP-1 analogues or DPP-4-inhibitors: A hot topic for cardiologists?
-
Jax T. Treatment of patients with diabetes with GLP-1 analogues or DPP-4-inhibitors: a hot topic for cardiologists? Clin Res Cardiol 98: 75-79, 2009.
-
(2009)
Clin Res Cardiol
, vol.98
, pp. 75-79
-
-
Jax, T.1
-
90
-
-
84855481995
-
Cardiovascular safety with linagliptin in patients with type 2 diabetes mellitus: A pre-specified, prospective, and adjudicated meta-analysis of a phase 3 programme
-
Johansen OE, Neubacher D, von Eynatten M, Patel S, Woerle HJ. Cardiovascular safety with linagliptin in patients with type 2 diabetes mellitus: a pre-specified, prospective, and adjudicated meta-analysis of a phase 3 programme. Cardiovasc Diabetol 11: 3, 2012.
-
(2012)
Cardiovasc Diabetol
, vol.11
, pp. 3
-
-
Johansen, O.E.1
Neubacher, D.2
von Eynatten, M.3
Patel, S.4
Woerle, H.J.5
-
91
-
-
84861091379
-
Cardiovascular effects of the DPP-4 inhibitors
-
Jose T, Inzucchi SE. Cardiovascular effects of the DPP-4 inhibitors. Diab Vasc Dis Res 9: 109-116, 2012.
-
(2012)
Diab Vasc Dis Res
, vol.9
, pp. 109-116
-
-
Jose, T.1
Inzucchi, S.E.2
-
92
-
-
84880780681
-
Mmp-9 inhibitors in the brain: Can old bullets shoot new targets?
-
Kaczmarek L. Mmp-9 inhibitors in the brain: can old bullets shoot new targets? Curr Pharm Des 19: 1085-1089, 2013.
-
(2013)
Curr Pharm Des
, vol.19
, pp. 1085-1089
-
-
Kaczmarek, L.1
-
93
-
-
84859174317
-
Dipeptidyl peptidase-4 inhibitors for treatment of type 2 diabetes mellitus in the clinical setting: Systematic review and meta-analysis
-
Karagiannis T, Paschos P, Paletas K, Matthews DR, Tsapas A. Dipeptidyl peptidase-4 inhibitors for treatment of type 2 diabetes mellitus in the clinical setting: systematic review and meta-analysis. BMJ 344: e1369, 2012.
-
(2012)
BMJ
, vol.344
-
-
Karagiannis, T.1
Paschos, P.2
Paletas, K.3
Matthews, D.R.4
Tsapas, A.5
-
94
-
-
84856120511
-
T regulatory lymphocytes prevent aldosterone-induced vascular injury
-
Kasal DA, Barhoumi T, Li MW, Yamamoto N, Zdanovich E, Rehman A, Neves MF, Laurant P, Paradis P, Schiffrin EL. T regulatory lymphocytes prevent aldosterone-induced vascular injury. Hypertension 59: 324-330, 2012.
-
(2012)
Hypertension
, vol.59
, pp. 324-330
-
-
Kasal, D.A.1
Barhoumi, T.2
Li, M.W.3
Yamamoto, N.4
Zdanovich, E.5
Rehman, A.6
Neves, M.F.7
Laurant, P.8
Paradis, P.9
Schiffrin, E.L.10
-
95
-
-
80054881428
-
Interleukin-10 released by CD4(+)CD25(+) natural regulatory T cells improves microvascular endothelial function through inhibition of NADPH oxidase activity in hypertensive mice
-
Kassan M, Galan M, Partyka M, Trebak M, Matrougui K. Interleukin-10 released by CD4(+)CD25(+) natural regulatory T cells improves microvascular endothelial function through inhibition of NADPH oxidase activity in hypertensive mice. Arterioscler Thromb Vasc Biol 31: 2534-2542, 2011.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 2534-2542
-
-
Kassan, M.1
Galan, M.2
Partyka, M.3
Trebak, M.4
Matrougui, K.5
-
96
-
-
33750459923
-
Putative contributors to the secular increase in obesity: Exploring the roads less traveled
-
Keith SW, Redden DT, Katzmarzyk PT, Boggiano MM, Hanlon EC, Benca RM, Ruden D, Pietrobelli A, Barger JL, Fontaine KR, Wang C, Aronne LJ, Wright SM, Baskin M, Dhurandhar NV, Lijoi MC, Grilo CM, DeLuca M, Westfall AO, Allison DB. Putative contributors to the secular increase in obesity: exploring the roads less traveled. Int J Obes (Lond) 30: 1585-1594, 2006.
-
(2006)
Int J Obes (Lond)
, vol.30
, pp. 1585-1594
-
-
Keith, S.W.1
Redden, D.T.2
Katzmarzyk, P.T.3
Boggiano, M.M.4
Hanlon, E.C.5
Benca, R.M.6
Ruden, D.7
Pietrobelli, A.8
Barger, J.L.9
Fontaine, K.R.10
Wang, C.11
Aronne, L.J.12
Wright, S.M.13
Baskin, M.14
Dhurandhar, N.V.15
Lijoi, M.C.16
Grilo, C.M.17
DeLuca, M.18
Westfall, A.O.19
Allison, D.B.20
more..
-
97
-
-
0017120734
-
Dipeptidyl peptidase IV, a kidney brush-border serine peptidase
-
Kenny AJ, Booth AG, George SG, Ingram J, Kershaw D, Wood EJ, Young AR. Dipeptidyl peptidase IV, a kidney brush-border serine peptidase. Biochem J 157: 169-182, 1976.
-
(1976)
Biochem J
, vol.157
, pp. 169-182
-
-
Kenny, A.J.1
Booth, A.G.2
George, S.G.3
Ingram, J.4
Kershaw, D.5
Wood, E.J.6
Young, A.R.7
-
98
-
-
84862692484
-
Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity
-
Kern M, Kloting N, Niessen HG, Thomas L, Stiller D, Mark M, Klein T, Bluher M. Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity. PLoS One 7: e38744, 2012.
-
(2012)
PLoS One
, vol.7
-
-
Kern, M.1
Kloting, N.2
Niessen, H.G.3
Thomas, L.4
Stiller, D.5
Mark, M.6
Klein, T.7
Bluher, M.8
-
99
-
-
84880140645
-
Diabetes mellitus: A risk factor for ischemic stroke in a large biracial population
-
Khoury JC, Kleindorfer D, Alwell K, Moomaw CJ, Woo D, Adeoye O, Flaherty ML, Khatri P, Ferioli S, Broderick JP, Kissela BM. Diabetes mellitus: a risk factor for ischemic stroke in a large biracial population. Stroke 44: 1500-1504, 2013.
-
(2013)
Stroke
, vol.44
, pp. 1500-1504
-
-
Khoury, J.C.1
Kleindorfer, D.2
Alwell, K.3
Moomaw, C.J.4
Woo, D.5
Adeoye, O.6
Flaherty, M.L.7
Khatri, P.8
Ferioli, S.9
Broderick, J.P.10
Kissela, B.M.11
-
100
-
-
63149159149
-
Increased plasma dipeptidyl peptidase IV (DPP IV) activity and decreased DPP IV activity of visceral but not subcutaneous adipose tissue in impaired glucose tolerance rats induced by high-fat or high-sucrose diet
-
Kirino Y, Kamimoto T, Sato Y, Kawazoe K, Minakuchi K, Nakahori Y. Increased plasma dipeptidyl peptidase IV (DPP IV) activity and decreased DPP IV activity of visceral but not subcutaneous adipose tissue in impaired glucose tolerance rats induced by high-fat or high-sucrose diet. Biol Pharm Bull 32: 463-467, 2009.
-
(2009)
Biol Pharm Bull
, vol.32
, pp. 463-467
-
-
Kirino, Y.1
Kamimoto, T.2
Sato, Y.3
Kawazoe, K.4
Minakuchi, K.5
Nakahori, Y.6
-
101
-
-
79251537449
-
Altered dipeptidyl peptidase-4 activity during the progression of hyperinsulinemic obesity and islet atrophy in spontaneously late-stage type 2 diabetic rats
-
Kirino Y, Sato Y, Kamimoto T, Kawazoe K, Minakuchi K. Altered dipeptidyl peptidase-4 activity during the progression of hyperinsulinemic obesity and islet atrophy in spontaneously late-stage type 2 diabetic rats. Am J Physiol Endocrinol Metab 300: E372-E379, 2011.
-
(2011)
Am J Physiol Endocrinol Metab
, vol.300
-
-
Kirino, Y.1
Sato, Y.2
Kamimoto, T.3
Kawazoe, K.4
Minakuchi, K.5
-
102
-
-
79953826349
-
Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes
-
Kodera R, Shikata K, Kataoka HU, Takatsuka T, Miyamoto S, Sasaki M, Kajitani N, Nishishita S, Sarai K, Hirota D, Sato C, Ogawa D, Makino H. Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes. Diabetologia 54: 965-978, 2011.
-
(2011)
Diabetologia
, vol.54
, pp. 965-978
-
-
Kodera, R.1
Shikata, K.2
Kataoka, H.U.3
Takatsuka, T.4
Miyamoto, S.5
Sasaki, M.6
Kajitani, N.7
Nishishita, S.8
Sarai, K.9
Hirota, D.10
Sato, C.11
Ogawa, D.12
Makino, H.13
-
103
-
-
84866644965
-
Glucose-independent improvement of vascular dysfunction in experimental sepsis by dipeptidyl-peptidase 4 inhibition
-
Kroller-Schon S, Knorr M, Hausding M, Oelze M, Schuff A, Schell R, Sudowe S, Scholz A, Daub S, Karbach S, Kossmann S, Gori T, Wenzel P, Schulz E, Grabbe S, Klein T, Munzel T, Daiber A. Glucose-independent improvement of vascular dysfunction in experimental sepsis by dipeptidyl-peptidase 4 inhibition. Cardiovasc Res 96: 140-149, 2012.
-
(2012)
Cardiovasc Res
, vol.96
, pp. 140-149
-
-
Kroller-Schon, S.1
Knorr, M.2
Hausding, M.3
Oelze, M.4
Schuff, A.5
Schell, R.6
Sudowe, S.7
Scholz, A.8
Daub, S.9
Karbach, S.10
Kossmann, S.11
Gori, T.12
Wenzel, P.13
Schulz, E.14
Grabbe, S.15
Klein, T.16
Munzel, T.17
Daiber, A.18
-
104
-
-
79952142784
-
Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle
-
Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, Inoue M, Itoh S, Takamoto I, Sasako T, Kumagai K, Kawai T, Hashimoto S, Kobayashi T, Sato M, Tokuyama K, Nishimura S, Tsunoda M, Ide T, Murakami K, Yamazaki T, Ezaki O, Kawamura K, Masuda H, Moroi M, Sugi K, Oike Y, Shimokawa H, Yanagihara N, Tsutsui M, Terauchi Y, Tobe K, Nagai R, Kamata K, Inoue K, Kodama T, Ueki K, Kadowaki T. Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle. Cell Metab 13: 294-307, 2011.
-
(2011)
Cell Metab
, vol.13
, pp. 294-307
-
-
Kubota, T.1
Kubota, N.2
Kumagai, H.3
Yamaguchi, S.4
Kozono, H.5
Takahashi, T.6
Inoue, M.7
Itoh, S.8
Takamoto, I.9
Sasako, T.10
Kumagai, K.11
Kawai, T.12
Hashimoto, S.13
Kobayashi, T.14
Sato, M.15
Tokuyama, K.16
Nishimura, S.17
Tsunoda, M.18
Ide, T.19
Murakami, K.20
Yamazaki, T.21
Ezaki, O.22
Kawamura, K.23
Masuda, H.24
Moroi, M.25
Sugi, K.26
Oike, Y.27
Shimokawa, H.28
Yanagihara, N.29
Tsutsui, M.30
Terauchi, Y.31
Tobe, K.32
Nagai, R.33
Kamata, K.34
Inoue, K.35
Kodama, T.36
Ueki, K.37
Kadowaki, T.38
more..
-
105
-
-
84872565644
-
The dipeptidyl peptidase-4 inhibitor sitagliptin improves vascular endothelial function in type 2 diabetes
-
Kubota Y, Miyamoto M, Takagi G, Ikeda T, Kirinoki-Ichikawa S, Tanaka K, Mizuno K. The dipeptidyl peptidase-4 inhibitor sitagliptin improves vascular endothelial function in type 2 diabetes. J Korean Med Sci 27: 1364-1370, 2012.
-
(2012)
J Korean Med Sci
, vol.27
, pp. 1364-1370
-
-
Kubota, Y.1
Miyamoto, M.2
Takagi, G.3
Ikeda, T.4
Kirinoki-Ichikawa, S.5
Tanaka, K.6
Mizuno, K.7
-
107
-
-
80052096595
-
Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome
-
Lamers D, Famulla S, Wronkowitz N, Hartwig S, Lehr S, Ouwens DM, Eckardt K, Kaufman JM, Ryden M, Muller S, Hanisch FG, Ruige J, Arner P, Sell H, Eckel J. Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome. Diabetes 60: 1917-1925, 2011.
-
(2011)
Diabetes
, vol.60
, pp. 1917-1925
-
-
Lamers, D.1
Famulla, S.2
Wronkowitz, N.3
Hartwig, S.4
Lehr, S.5
Ouwens, D.M.6
Eckardt, K.7
Kaufman, J.M.8
Ryden, M.9
Muller, S.10
Hanisch, F.G.11
Ruige, J.12
Arner, P.13
Sell, H.14
Eckel, J.15
-
108
-
-
79955608846
-
Ischemia-induced changes in glucagon-like peptide-1 receptor and neuroprotective effect of its agonist, exendin-4, in experimental transient cerebral ischemia
-
Lee CH, Yan B, Yoo KY, Choi JH, Kwon SH, Her S, Sohn Y, Hwang IK, Cho JH, Kim YM, Won MH. Ischemia-induced changes in glucagon-like peptide-1 receptor and neuroprotective effect of its agonist, exendin-4, in experimental transient cerebral ischemia. J Neurosci Res 89: 1103-1113, 2011.
-
(2011)
J Neurosci Res
, vol.89
, pp. 1103-1113
-
-
Lee, C.H.1
Yan, B.2
Yoo, K.Y.3
Choi, J.H.4
Kwon, S.H.5
Her, S.6
Sohn, Y.7
Hwang, I.K.8
Cho, J.H.9
Kim, Y.M.10
Won, M.H.11
-
109
-
-
84878485447
-
CD26/DPP4 levels in peripheral blood and t cells in patients with type 2 diabetes mellitus
-
Lee SA, Kim YR, Yang EJ, Kwon EJ, Kim SH, Kang SH, Park DB, Oh BC, Kim J, Heo ST, Koh G, Lee DH. CD26/DPP4 levels in peripheral blood and t cells in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab 98: 2553-2561, 2013.
-
(2013)
J Clin Endocrinol Metab
, vol.98
, pp. 2553-2561
-
-
Lee, S.A.1
Kim, Y.R.2
Yang, E.J.3
Kwon, E.J.4
Kim, S.H.5
Kang, S.H.6
Park, D.B.7
Oh, B.C.8
Kim, J.9
Heo, S.T.10
Koh, G.11
Lee, D.H.12
-
110
-
-
84891602725
-
Cellular and molecular mechanisms of arterial stiffness associated with obesity
-
Leopold JA. Cellular and molecular mechanisms of arterial stiffness associated with obesity. Hypertension 62: 1003-1004, 2013.
-
(2013)
Hypertension
, vol.62
, pp. 1003-1004
-
-
Leopold, J.A.1
-
111
-
-
84899029163
-
Incretin treatment and risk of pancreatitis in patients with type 2 diabetes mellitus: Systematic review and meta-analysis of randomised and non-randomised studies
-
Li L, Shen J, Bala MM, Busse JW, Ebrahim S, Vandvik PO, Rios LP, Malaga G, Wong E, Sohani Z, Guyatt GH, Sun X. Incretin treatment and risk of pancreatitis in patients with type 2 diabetes mellitus: systematic review and meta-analysis of randomised and non-randomised studies. BMJ 348: g2366, 2014.
-
(2014)
BMJ
, vol.348
-
-
Li, L.1
Shen, J.2
Bala, M.M.3
Busse, J.W.4
Ebrahim, S.5
Vandvik, P.O.6
Rios, L.P.7
Malaga, G.8
Wong, E.9
Sohani, Z.10
Guyatt, G.H.11
Sun, X.12
-
112
-
-
84874602308
-
Endothelial progenitor cell dysfunction in cardiovascular diseases: Role of reactive oxygen species and inflammation
-
Lin CP, Lin FY, Huang PH, Chen YL, Chen WC, Chen HY, Huang YC, Liao WL, Huang HC, Liu PL, Chen YH. Endothelial progenitor cell dysfunction in cardiovascular diseases: role of reactive oxygen species and inflammation. Biomed Res Int 2013: 845037, 2013.
-
(2013)
Biomed Res Int
, vol.2013
, pp. 845037
-
-
Lin, C.P.1
Lin, F.Y.2
Huang, P.H.3
Chen, Y.L.4
Chen, W.C.5
Chen, H.Y.6
Huang, Y.C.7
Liao, W.L.8
Huang, H.C.9
Liu, P.L.10
Chen, Y.H.11
-
113
-
-
78651062856
-
Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice
-
Liu G, Ma H, Qiu L, Li L, Cao Y, Ma J, Zhao Y. Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice. Immunol Cell Biol 89: 130-142, 2011.
-
(2011)
Immunol Cell Biol
, vol.89
, pp. 130-142
-
-
Liu, G.1
Ma, H.2
Qiu, L.3
Li, L.4
Cao, Y.5
Ma, J.6
Zhao, Y.7
-
114
-
-
84865492970
-
Dipeptidyl peptidase 4 inhibitor sitagliptin protects endothelial function in hypertension through a glucagon-like peptide 1-dependent mechanism
-
Liu L, Liu J, Wong WT, Tian XY, Lau CW, Wang YX, Xu G, Pu Y, Zhu Z, Xu A, Lam KS, Chen ZY, Ng CF, Yao X, Huang Y. Dipeptidyl peptidase 4 inhibitor sitagliptin protects endothelial function in hypertension through a glucagon-like peptide 1-dependent mechanism. Hypertension 60: 833-841, 2012.
-
(2012)
Hypertension
, vol.60
, pp. 833-841
-
-
Liu, L.1
Liu, J.2
Wong, W.T.3
Tian, X.Y.4
Lau, C.W.5
Wang, Y.X.6
Xu, G.7
Pu, Y.8
Zhu, Z.9
Xu, A.10
Lam, K.S.11
Chen, Z.Y.12
Ng, C.F.13
Yao, X.14
Huang, Y.15
-
115
-
-
84862944057
-
Dipeptidyl peptidase IV inhibitor attenuates kidney injury in streptozotocin-induced diabetic rats
-
Liu WJ, Xie SH, Liu YN, Kim W, Jin HY, Park SK, Shao YM, Park TS. Dipeptidyl peptidase IV inhibitor attenuates kidney injury in streptozotocin-induced diabetic rats. J Pharmacol Exp Ther 340: 248-255, 2012.
-
(2012)
J Pharmacol Exp Ther
, vol.340
, pp. 248-255
-
-
Liu, W.J.1
Xie, S.H.2
Liu, Y.N.3
Kim, W.4
Jin, H.Y.5
Park, S.K.6
Shao, Y.M.7
Park, T.S.8
-
116
-
-
9144271032
-
Endothelial progenitor cell dysfunction: A novel concept in the pathogenesis of vascular complications of type 1 diabetes
-
Loomans CJ, de Koning EJ, Staal FJ, Rookmaaker MB, Verseyden C, de Boer HC, Verhaar MC, Braam B, Rabelink TJ, van Zonneveld AJ. Endothelial progenitor cell dysfunction: a novel concept in the pathogenesis of vascular complications of type 1 diabetes. Diabetes 53: 195-199, 2004.
-
(2004)
Diabetes
, vol.53
, pp. 195-199
-
-
Loomans, C.J.1
de Koning, E.J.2
Staal, F.J.3
Rookmaaker, M.B.4
Verseyden, C.5
de Boer, H.C.6
Verhaar, M.C.7
Braam, B.8
Rabelink, T.J.9
van Zonneveld, A.J.10
-
117
-
-
0034648768
-
Atherosclerosis
-
Lusis AJ. Atherosclerosis. Nature 407: 233-241, 2000.
-
(2000)
Nature
, vol.407
, pp. 233-241
-
-
Lusis, A.J.1
-
119
-
-
84867231203
-
Significance of circulating endothelial progenitor cells in patients with fracture healing process
-
Ma XL, Sun XL, Wan CY, Ma JX, Tian P. Significance of circulating endothelial progenitor cells in patients with fracture healing process. J Orthop Res 30: 1860-1866, 2012.
-
(2012)
J Orthop Res
, vol.30
, pp. 1860-1866
-
-
Ma, X.L.1
Sun, X.L.2
Wan, C.Y.3
Ma, J.X.4
Tian, P.5
-
120
-
-
74949108521
-
Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction
-
Madhur MS, Lob HE, McCann LA, Iwakura Y, Blinder Y, Guzik TJ, Harrison DG. Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction. Hypertension 55: 500-507, 2010.
-
(2010)
Hypertension
, vol.55
, pp. 500-507
-
-
Madhur, M.S.1
Lob, H.E.2
McCann, L.A.3
Iwakura, Y.4
Blinder, Y.5
Guzik, T.J.6
Harrison, D.G.7
-
121
-
-
77957231074
-
Interactive hemodynamic effects of dipeptidyl peptidase-IV inhibition and angiotensinconverting enzyme inhibition in humans
-
Marney A, Kunchakarra S, Byrne L, Brown NJ. Interactive hemodynamic effects of dipeptidyl peptidase-IV inhibition and angiotensinconverting enzyme inhibition in humans. Hypertension 56: 728-733, 2010.
-
(2010)
Hypertension
, vol.56
, pp. 728-733
-
-
Marney, A.1
Kunchakarra, S.2
Byrne, L.3
Brown, N.J.4
-
122
-
-
84870053428
-
Dipeptidyl peptidase-4 inhibition with saxagliptin enhanced nitric oxide release and reduced blood pressure and sICAM-1 levels in hypertensive rats
-
Mason RP, Jacob RF, Kubant R, Ciszewski A, Corbalan JJ, Malinski T. Dipeptidyl peptidase-4 inhibition with saxagliptin enhanced nitric oxide release and reduced blood pressure and sICAM-1 levels in hypertensive rats. J Cardiovasc Pharmacol 60: 467-473, 2012.
-
(2012)
J Cardiovasc Pharmacol
, vol.60
, pp. 467-473
-
-
Mason, R.P.1
Jacob, R.F.2
Kubant, R.3
Ciszewski, A.4
Corbalan, J.J.5
Malinski, T.6
-
123
-
-
85085223668
-
Treatment with linagliptin can attenuate postprandial hyperlipidemia (abstract)
-
In: Chicago, IL
-
Masuda D, Koybayashi T, Okada T, Nakaoka H, Kawase R, Nakatani K, Ohama T, Nishida M, Matsuyama A, Komuro I, Yamashita S. Treatment with linagliptin can attenuate postprandial hyperlipidemia (abstract). In: Proceedings of the 73rd Annual Scientific Sessions of the American Diabetes Association. Chicago, IL: 2013, p. A77.
-
(2013)
Proceedings of the 73rd Annual Scientific Sessions of the American Diabetes Association
-
-
Masuda, D.1
Koybayashi, T.2
Okada, T.3
Nakaoka, H.4
Kawase, R.5
Nakatani, K.6
Ohama, T.7
Nishida, M.8
Matsuyama, A.9
Komuro, I.10
Yamashita, S.11
-
124
-
-
33746690405
-
Vildagliptin therapy reduces postprandial intestinal triglyceride-rich lipoprotein particles in patients with type 2 diabetes
-
Matikainen N, Manttari S, Schweizer A, Ulvestad A, Mills D, Dunning BE, Foley JE, Taskinen MR. Vildagliptin therapy reduces postprandial intestinal triglyceride-rich lipoprotein particles in patients with type 2 diabetes. Diabetologia 49: 2049-2057, 2006.
-
(2006)
Diabetologia
, vol.49
, pp. 2049-2057
-
-
Matikainen, N.1
Manttari, S.2
Schweizer, A.3
Ulvestad, A.4
Mills, D.5
Dunning, B.E.6
Foley, J.E.7
Taskinen, M.R.8
-
125
-
-
84862908699
-
A dipeptidyl peptidase-4 inhibitor, des-fluoro-sitagliptin, improves endothelial function and reduces atherosclerotic lesion formation in apolipoprotein E-deficient mice
-
Matsubara J, Sugiyama S, Sugamura K, Nakamura T, Fujiwara Y, Akiyama E, Kurokawa H, Nozaki T, Ohba K, Konishi M, Maeda H, Izumiya Y, Kaikita K, Sumida H, Jinnouchi H, Matsui K, Kim-Mitsuyama S, Takeya M, Ogawa H. A dipeptidyl peptidase-4 inhibitor, des-fluoro-sitagliptin, improves endothelial function and reduces atherosclerotic lesion formation in apolipoprotein E-deficient mice. J Am Coll Cardiol 59: 265-276, 2012.
-
(2012)
J Am Coll Cardiol
, vol.59
, pp. 265-276
-
-
Matsubara, J.1
Sugiyama, S.2
Sugamura, K.3
Nakamura, T.4
Fujiwara, Y.5
Akiyama, E.6
Kurokawa, H.7
Nozaki, T.8
Ohba, K.9
Konishi, M.10
Maeda, H.11
Izumiya, Y.12
Kaikita, K.13
Sumida, H.14
Jinnouchi, H.15
Matsui, K.16
Kim-Mitsuyama, S.17
Takeya, M.18
Ogawa, H.19
-
126
-
-
79955480528
-
Vildagliptin blocks vascular injury in thoracic aorta of diabetic rats by suppressing advanced glycation end product-receptor axis
-
Matsui T, Nishino Y, Takeuchi M, Yamagishi S. Vildagliptin blocks vascular injury in thoracic aorta of diabetic rats by suppressing advanced glycation end product-receptor axis. Pharmacol Res 63: 383-388, 2011.
-
(2011)
Pharmacol Res
, vol.63
, pp. 383-388
-
-
Matsui, T.1
Nishino, Y.2
Takeuchi, M.3
Yamagishi, S.4
-
127
-
-
79951711994
-
The pleiotropic effects of ARB in vascular endothelial progenitor cells
-
Matsuura K, Hagiwara N. The pleiotropic effects of ARB in vascular endothelial progenitor cells. Curr Vasc Pharmacol 9: 153-157, 2011.
-
(2011)
Curr Vasc Pharmacol
, vol.9
, pp. 153-157
-
-
Matsuura, K.1
Hagiwara, N.2
-
128
-
-
71549137150
-
Ten putative contributors to the obesity epidemic
-
McAllister EJ, Dhurandhar NV, Keith SW, Aronne LJ, Barger J, Baskin M, Benca RM, Biggio J, Boggiano MM, Eisenmann JC, Elobeid M, Fontaine KR, Gluckman P, Hanlon EC, Katzmarzyk P, Pietrobelli A, Redden DT, Ruden DM, Wang C, Waterland RA, Wright SM, Allison DB. Ten putative contributors to the obesity epidemic. Crit Rev Food Sci Nutr 49: 868-913, 2009.
-
(2009)
Crit Rev Food Sci Nutr
, vol.49
, pp. 868-913
-
-
McAllister, E.J.1
Dhurandhar, N.V.2
Keith, S.W.3
Aronne, L.J.4
Barger, J.5
Baskin, M.6
Benca, R.M.7
Biggio, J.8
Boggiano, M.M.9
Eisenmann, J.C.10
Elobeid, M.11
Fontaine, K.R.12
Gluckman, P.13
Hanlon, E.C.14
Katzmarzyk, P.15
Pietrobelli, A.16
Redden, D.T.17
Ruden, D.M.18
Wang, C.19
Waterland, R.A.20
Wright, S.M.21
Allison, D.B.22
more..
-
129
-
-
0034074276
-
Molecular pathogenesis of liver disease: An approach to hepatic inflammation, cirrhosis and liver transplant tolerance
-
McCaughan GW, Gorrell MD, Bishop GA, Abbott CA, Shackel NA, McGuinness PH, Levy MT, Sharland AF, Bowen DG, Yu D, Slaitini L, Church WB, Napoli J. Molecular pathogenesis of liver disease: an approach to hepatic inflammation, cirrhosis and liver transplant tolerance. Immunol Rev 174: 172-191, 2000.
-
(2000)
Immunol Rev
, vol.174
, pp. 172-191
-
-
McCaughan, G.W.1
Gorrell, M.D.2
Bishop, G.A.3
Abbott, C.A.4
Shackel, N.A.5
McGuinness, P.H.6
Levy, M.T.7
Sharland, A.F.8
Bowen, D.G.9
Yu, D.10
Slaitini, L.11
Church, W.B.12
Napoli, J.13
-
130
-
-
79955749452
-
The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease
-
McClean PL, Parthsarathy V, Faivre E, Holscher C. The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease. J Neurosci 31: 6587-6594, 2011.
-
(2011)
J Neurosci
, vol.31
, pp. 6587-6594
-
-
McClean, P.L.1
Parthsarathy, V.2
Faivre, E.3
Holscher, C.4
-
131
-
-
0027215348
-
Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum
-
Mentlein R, Gallwitz B, Schmidt WE. Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum. Eur J Biochem 214: 829-835, 1993.
-
(1993)
Eur J Biochem
, vol.214
, pp. 829-835
-
-
Mentlein, R.1
Gallwitz, B.2
Schmidt, W.E.3
-
132
-
-
41849099939
-
Effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on blood pressure in nondiabetic patients with mild to moderate hypertension
-
Mistry GC, Maes AL, Lasseter KC, Davies MJ, Gottesdiener KM, Wagner JA, Herman GA. Effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on blood pressure in nondiabetic patients with mild to moderate hypertension. J Clin Pharmacol 48: 592-598, 2008.
-
(2008)
J Clin Pharmacol
, vol.48
, pp. 592-598
-
-
Mistry, G.C.1
Maes, A.L.2
Lasseter, K.C.3
Davies, M.J.4
Gottesdiener, K.M.5
Wagner, J.A.6
Herman, G.A.7
-
133
-
-
84871936025
-
Dipeptidyl peptidase-4 inhibitors and cardiovascular risk: A meta-analysis of randomized clinical trials
-
Monami M, Ahren B, Dicembrini I, Mannucci E. Dipeptidyl peptidase-4 inhibitors and cardiovascular risk: a meta-analysis of randomized clinical trials. Diabetes Obes Metab 15: 112-120, 2013.
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 112-120
-
-
Monami, M.1
Ahren, B.2
Dicembrini, I.3
Mannucci, E.4
-
134
-
-
77950880269
-
Dipeptydil peptidase-4 inhibitors in type 2 diabetes: A meta-analysis of randomized clinical trials
-
Monami M, Iacomelli I, Marchionni N, Mannucci E. Dipeptydil peptidase-4 inhibitors in type 2 diabetes: a meta-analysis of randomized clinical trials. Nutr Metab Cardiovasc Dis 20: 224-235, 2010.
-
(2010)
Nutr Metab Cardiovasc Dis
, vol.20
, pp. 224-235
-
-
Monami, M.1
Iacomelli, I.2
Marchionni, N.3
Mannucci, E.4
-
135
-
-
84863087938
-
Endothelial dysfunction and cardiovascular disease in early-stage chronic kidney disease: Cause or association?
-
Moody WE, Edwards NC, Madhani M, Chue CD, Steeds RP, Ferro CJ, Townend JN. Endothelial dysfunction and cardiovascular disease in early-stage chronic kidney disease: cause or association? Atherosclerosis 223: 86-94, 2012.
-
(2012)
Atherosclerosis
, vol.223
, pp. 86-94
-
-
Moody, W.E.1
Edwards, N.C.2
Madhani, M.3
Chue, C.D.4
Steeds, R.P.5
Ferro, C.J.6
Townend, J.N.7
-
136
-
-
84874649487
-
Role of insulin resistance in endothelial dysfunction
-
Muniyappa R, Sowers JR. Role of insulin resistance in endothelial dysfunction. Rev Endocr Metab Disord 14: 5-12, 2013.
-
(2013)
Rev Endocr Metab Disord
, vol.14
, pp. 5-12
-
-
Muniyappa, R.1
Sowers, J.R.2
-
137
-
-
84882245955
-
Is endothelial dysfunction more deleterious than podocyte injury in diabetic nephropathy?
-
Nakagawa T. Is endothelial dysfunction more deleterious than podocyte injury in diabetic nephropathy? Kidney Int 83: 1202-1203, 2013.
-
(2013)
Kidney Int
, vol.83
, pp. 1202-1203
-
-
Nakagawa, T.1
-
138
-
-
78650522881
-
Endothelial dysfunction as a potential contributor in diabetic nephropathy
-
Nakagawa T, Tanabe K, Croker BP, Johnson RJ, Grant MB, Kosugi T, Li Q. Endothelial dysfunction as a potential contributor in diabetic nephropathy. Nat Rev Nephrol 7: 36-44, 2011.
-
(2011)
Nat Rev Nephrol
, vol.7
, pp. 36-44
-
-
Nakagawa, T.1
Tanabe, K.2
Croker, B.P.3
Johnson, R.J.4
Grant, M.B.5
Kosugi, T.6
Li, Q.7
-
139
-
-
0022617246
-
Reduced incretin effect in type 2 (non-insulin-dependent) diabetes
-
Nauck M, Stockmann F, Ebert R, Creutzfeldt W. Reduced incretin effect in type 2 (non-insulin-dependent) diabetes. Diabetologia 29: 46-52, 1986.
-
(1986)
Diabetologia
, vol.29
, pp. 46-52
-
-
Nauck, M.1
Stockmann, F.2
Ebert, R.3
Creutzfeldt, W.4
-
140
-
-
84879231610
-
A critical analysis of the clinical use of incretin-based therapies: The benefits by far outweigh the potential risks
-
Nauck MA. A critical analysis of the clinical use of incretin-based therapies: the benefits by far outweigh the potential risks. Diabetes Care 36: 2126-2132, 2013.
-
(2013)
Diabetes Care
, vol.36
, pp. 2126-2132
-
-
Nauck, M.A.1
-
141
-
-
0027391607
-
Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus
-
Nauck MA, Heimesaat MM, Orskov C, Holst JJ, Ebert R, Creutzfeldt W. Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. J Clin Invest 91: 301-307, 1993.
-
(1993)
J Clin Invest
, vol.91
, pp. 301-307
-
-
Nauck, M.A.1
Heimesaat, M.M.2
Orskov, C.3
Holst, J.J.4
Ebert, R.5
Creutzfeldt, W.6
-
142
-
-
84872020915
-
Alogliptin ameliorates postprandial lipemia and postprandial endothelial dysfunction in non-diabetic subjects: A preliminary report
-
Noda Y, Miyoshi T, Oe H, Ohno Y, Nakamura K, Toh N, Kohno K, Morita H, Kusano K, Ito H. Alogliptin ameliorates postprandial lipemia and postprandial endothelial dysfunction in non-diabetic subjects: a preliminary report. Cardiovasc Diabetol 12: 8, 2013.
-
(2013)
Cardiovasc Diabetol
, vol.12
, pp. 8
-
-
Noda, Y.1
Miyoshi, T.2
Oe, H.3
Ohno, Y.4
Nakamura, K.5
Toh, N.6
Kohno, K.7
Morita, H.8
Kusano, K.9
Ito, H.10
-
143
-
-
64649102619
-
GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice
-
Noyan-Ashraf MH, Momen MA, Ban K, Sadi AM, Zhou YQ, Riazi AM, Baggio LL, Henkelman RM, Husain M, Drucker DJ. GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice. Diabetes 58: 975-983, 2009.
-
(2009)
Diabetes
, vol.58
, pp. 975-983
-
-
Noyan-Ashraf, M.H.1
Momen, M.A.2
Ban, K.3
Sadi, A.M.4
Zhou, Y.Q.5
Riazi, A.M.6
Baggio, L.L.7
Henkelman, R.M.8
Husain, M.9
Drucker, D.J.10
-
144
-
-
77953959949
-
Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A
-
Oeseburg H, de Boer RA, Buikema H, van der Harst P, van Gilst WH, Sillje HH. Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A. Arterioscler Thromb Vasc Biol 30: 1407-1414, 2010.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 1407-1414
-
-
Oeseburg, H.1
de Boer, R.A.2
Buikema, H.3
van der Harst, P.4
van Gilst, W.H.5
Sillje, H.H.6
-
145
-
-
79955952000
-
Sitagliptin, a dipeptidyl peptidase-4 inhibitor, decreases systolic blood pressure in Japanese hypertensive patients with type 2 diabetes
-
Ogawa S, Ishiki M, Nako K, Okamura M, Senda M, Mori T, Ito S. Sitagliptin, a dipeptidyl peptidase-4 inhibitor, decreases systolic blood pressure in Japanese hypertensive patients with type 2 diabetes. Tohoku J Exp Med 223: 133-135, 2011.
-
(2011)
Tohoku J Exp Med
, vol.223
, pp. 133-135
-
-
Ogawa, S.1
Ishiki, M.2
Nako, K.3
Okamura, M.4
Senda, M.5
Mori, T.6
Ito, S.7
-
146
-
-
84856433589
-
Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010
-
Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010. JAMA 307: 483-490, 2012.
-
(2012)
JAMA
, vol.307
, pp. 483-490
-
-
Ogden, C.L.1
Carroll, M.D.2
Kit, B.K.3
Flegal, K.M.4
-
148
-
-
79951677095
-
Dipeptidyl peptidase IV inhibition attenuates blood pressure rising in young spontaneously hypertensive rats
-
Pacheco BP, Crajoinas RO, Couto GK, Davel AP, Lessa LM, Rossoni LV, Girardi AC. Dipeptidyl peptidase IV inhibition attenuates blood pressure rising in young spontaneously hypertensive rats. J Hypertens 29: 520-528, 2011.
-
(2011)
J Hypertens
, vol.29
, pp. 520-528
-
-
Pacheco, B.P.1
Crajoinas, R.O.2
Couto, G.K.3
Davel, A.P.4
Lessa, L.M.5
Rossoni, L.V.6
Girardi, A.C.7
-
149
-
-
84901296916
-
DPP4 inhibition in human kidney proximal tubular cells-renoprotection in diabetic nephropathy?
-
Panchapakesan UGS, Komala MG, Pegg K, Pollock CA. DPP4 inhibition in human kidney proximal tubular cells-renoprotection in diabetic nephropathy? J Diab Metab S9-007, 2013.
-
(2013)
J Diab Metab
-
-
Panchapakesan, U.G.S.1
Komala, M.G.2
Pegg, K.3
Pollock, C.A.4
-
150
-
-
84871706890
-
Role of GLP-1 and DPP-4 in diabetic nephropathy and cardiovascular disease
-
Panchapakesan U, Mather A, Pollock C. Role of GLP-1 and DPP-4 in diabetic nephropathy and cardiovascular disease. Clin Sci (Lond) 124: 17-26, 2013.
-
(2013)
Clin Sci (Lond)
, vol.124
, pp. 17-26
-
-
Panchapakesan, U.1
Mather, A.2
Pollock, C.3
-
151
-
-
75749104166
-
Left ventricular diastolic function in type 2 diabetes mellitus: Prevalence and association with myocardial and vascular disease
-
Poulsen MK, Henriksen JE, Dahl J, Johansen A, Gerke O, Vach W, Haghfelt T, Hoilund-Carlsen PF, Beck-Nielsen H, Moller JE. Left ventricular diastolic function in type 2 diabetes mellitus: prevalence and association with myocardial and vascular disease. Circ Cardiovasc Imaging 3: 24-31, 2010.
-
(2010)
Circ Cardiovasc Imaging
, vol.3
, pp. 24-31
-
-
Poulsen, M.K.1
Henriksen, J.E.2
Dahl, J.3
Johansen, A.4
Gerke, O.5
Vach, W.6
Haghfelt, T.7
Hoilund-Carlsen, P.F.8
Beck-Nielsen, H.9
Moller, J.E.10
-
152
-
-
77952309372
-
Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: A 26-week, randomised, parallel-group, open-label trial
-
Pratley RE, Nauck M, Bailey T, Montanya E, Cuddihy R, Filetti S, Thomsen AB, Sondergaard RE, Davies M, Group LDS. Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial. Lancet 375: 1447-1456, 2010.
-
(2010)
Lancet
, vol.375
, pp. 1447-1456
-
-
Pratley, R.E.1
Nauck, M.2
Bailey, T.3
Montanya, E.4
Cuddihy, R.5
Filetti, S.6
Thomsen, A.B.7
Sondergaard, R.E.8
Davies, M.9
Group, L.D.S.10
-
153
-
-
37349082926
-
Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease
-
Raffetto JD, Khalil RA. Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease. Biochem Pharmacol 75: 346-359, 2008.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 346-359
-
-
Raffetto, J.D.1
Khalil, R.A.2
-
154
-
-
84888876440
-
Clinical practice considerations and review of the literature for the use of DPP-4 inhibitors in patients with type 2 diabetes and chronic kidney disease
-
Ramirez G, Morrison AD, Bittle PA. Clinical practice considerations and review of the literature for the use of DPP-4 inhibitors in patients with type 2 diabetes and chronic kidney disease. Endocr Prac 19: 1025-1034, 2013.
-
(2013)
Endocr Prac
, vol.19
, pp. 1025-1034
-
-
Ramirez, G.1
Morrison, A.D.2
Bittle, P.A.3
-
155
-
-
84871179173
-
Linagliptin increases incretin levels, lowers glucagon, and improves glycemic control in type 2 diabetes mellitus
-
Rauch T, Graefe-Mody U, Deacon CF, Ring A, Holst JJ, Woerle HJ, Dugi KA, Heise T. Linagliptin increases incretin levels, lowers glucagon, and improves glycemic control in type 2 diabetes mellitus. Diabetes Ther 3: 10, 2012.
-
(2012)
Diabetes Ther
, vol.3
, pp. 10
-
-
Rauch, T.1
Graefe-Mody, U.2
Deacon, C.F.3
Ring, A.4
Holst, J.J.5
Woerle, H.J.6
Dugi, K.A.7
Heise, T.8
-
156
-
-
84885007790
-
The activity of circulating dipeptidyl peptidase-4 is associated with subclinical left ventricular dysfunction in patients with type 2 diabetes mellitus
-
Ravassa S, Barba J, Coma-Canella I, Huerta A, Lopez B, Gonzalez A, Diez J. The activity of circulating dipeptidyl peptidase-4 is associated with subclinical left ventricular dysfunction in patients with type 2 diabetes mellitus. Cardiovasc Diabetol 12: 143, 2013.
-
(2013)
Cardiovasc Diabetol
, vol.12
, pp. 143
-
-
Ravassa, S.1
Barba, J.2
Coma-Canella, I.3
Huerta, A.4
Lopez, B.5
Gonzalez, A.6
Diez, J.7
-
158
-
-
3543067962
-
Neurodegenerative disorders associated with diabetes mellitus
-
Ristow M. Neurodegenerative disorders associated with diabetes mellitus. J Mol Med (Berl) 82: 510-529, 2004.
-
(2004)
J Mol Med (Berl)
, vol.82
, pp. 510-529
-
-
Ristow, M.1
-
159
-
-
84859319452
-
Inflammatory concepts of obesity
-
Rocha VZ, Folco EJ. Inflammatory concepts of obesity. Int J Inflam 2011: 529061, 2011.
-
(2011)
Int J Inflam
, vol.2011
, pp. 529061
-
-
Rocha, V.Z.1
Folco, E.J.2
-
160
-
-
84879324855
-
Cardiovascular outcome trials in type 2 diabetes and the sulphonylurea controversy: Rationale for the active-comparator CAROLINA trial
-
Rosenstock J, Marx N, Kahn SE, Zinman B, Kastelein JJ, Lachin JM, Bluhmki E, Patel S, Johansen OE, Woerle HJ. Cardiovascular outcome trials in type 2 diabetes and the sulphonylurea controversy: rationale for the active-comparator CAROLINA trial. Diab Vasc Dis Res 10: 289-301, 2013.
-
(2013)
Diab Vasc Dis Res
, vol.10
, pp. 289-301
-
-
Rosenstock, J.1
Marx, N.2
Kahn, S.E.3
Zinman, B.4
Kastelein, J.J.5
Lachin, J.M.6
Bluhmki, E.7
Patel, S.8
Johansen, O.E.9
Woerle, H.J.10
-
161
-
-
79957487176
-
Subclinical regional left ventricular dysfunction in obese patients with and without hypertension or hypertrophy
-
Santos JL, Salemi VM, Picard MH, Mady C, Coelho OR. Subclinical regional left ventricular dysfunction in obese patients with and without hypertension or hypertrophy. Obesity (Silver Spring) 19: 1296-1303, 2011.
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 1296-1303
-
-
Santos, J.L.1
Salemi, V.M.2
Picard, M.H.3
Mady, C.4
Coelho, O.R.5
-
162
-
-
77951168113
-
Genetic deletion or pharmacological inhibition of dipeptidyl peptidase-4 improves cardiovascular outcomes after myocardial infarction in mice
-
Sauve M, Ban K, Momen MA, Zhou YQ, Henkelman RM, Husain M, Drucker DJ. Genetic deletion or pharmacological inhibition of dipeptidyl peptidase-4 improves cardiovascular outcomes after myocardial infarction in mice. Diabetes 59: 1063-1073, 2010.
-
(2010)
Diabetes
, vol.59
, pp. 1063-1073
-
-
Sauve, M.1
Ban, K.2
Momen, M.A.3
Zhou, Y.Q.4
Henkelman, R.M.5
Husain, M.6
Drucker, D.J.7
-
163
-
-
77955456705
-
Pharmacokinetics of dipeptidylpeptidase-4 inhibitors
-
Scheen AJ. Pharmacokinetics of dipeptidylpeptidase-4 inhibitors. Diabetes Obes Metab 12: 648-658, 2010.
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 648-658
-
-
Scheen, A.J.1
-
164
-
-
84886672246
-
Immune mechanisms in hypertension and vascular injury
-
Schiffrin EL. Immune mechanisms in hypertension and vascular injury. Clin Sci (Lond) 126: 267-274, 2014.
-
(2014)
Clin Sci (Lond)
, vol.126
, pp. 267-274
-
-
Schiffrin, E.L.1
-
165
-
-
33947584619
-
Glucagon-like peptide 1 receptor expression in primary porcine proximal tubular cells
-
Schlatter P, Beglinger C, Drewe J, Gutmann H. Glucagon-like peptide 1 receptor expression in primary porcine proximal tubular cells. Regul Pept 141: 120-128, 2007.
-
(2007)
Regul Pept
, vol.141
, pp. 120-128
-
-
Schlatter, P.1
Beglinger, C.2
Drewe, J.3
Gutmann, H.4
-
166
-
-
84862495415
-
The dipeptidyl peptidase-4 inhibitor linagliptin attenuates inflammation and accelerates epithelialization in wounds of diabetic ob/ob mice
-
Schurmann C, Linke A, Engelmann-Pilger K, Steinmetz C, Mark M, Pfeilschifter J, Klein T, Frank S. The dipeptidyl peptidase-4 inhibitor linagliptin attenuates inflammation and accelerates epithelialization in wounds of diabetic ob/ob mice. J Pharmacol Exp Ther 342: 71-80, 2012.
-
(2012)
J Pharmacol Exp Ther
, vol.342
, pp. 71-80
-
-
Schurmann, C.1
Linke, A.2
Engelmann-Pilger, K.3
Steinmetz, C.4
Mark, M.5
Pfeilschifter, J.6
Klein, T.7
Frank, S.8
-
167
-
-
84883765959
-
Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus
-
SAVOR-TIMI 53 Steering Committee and Investigators
-
Scirica BM, Bhatt DL, Braunwald E, Steg PG, Davidson J, Hirshberg B, Ohman P, Frederich R, Wiviott SD, Hoffman EB, Cavender MA, Udell JA, Desai NR, Mozenson O, McGuire DK, Ray KK, Leiter LA, Raz I; SAVOR-TIMI 53 Steering Committee and Investigators. Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus. N Engl J Med 369: 1317-1326, 2013.
-
(2013)
N Engl J Med
, vol.369
, pp. 1317-1326
-
-
Scirica, B.M.1
Bhatt, D.L.2
Braunwald, E.3
Steg, P.G.4
Davidson, J.5
Hirshberg, B.6
Ohman, P.7
Frederich, R.8
Wiviott, S.D.9
Hoffman, E.B.10
Cavender, M.A.11
Udell, J.A.12
Desai, N.R.13
Mozenson, O.14
McGuire, D.K.15
Ray, K.K.16
Leiter, L.A.17
Raz, I.18
-
168
-
-
81855222104
-
Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis
-
Shah Z, Kampfrath T, Deiuliis JA, Zhong J, Pineda C, Ying Z, Xu X, Lu B, Moffatt-Bruce S, Durairaj R, Sun Q, Mihai G, Maiseyeu A, Rajagopalan S. Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis. Circulation 124: 2338-2349, 2011.
-
(2011)
Circulation
, vol.124
, pp. 2338-2349
-
-
Shah, Z.1
Kampfrath, T.2
Deiuliis, J.A.3
Zhong, J.4
Pineda, C.5
Ying, Z.6
Xu, X.7
Lu, B.8
Moffatt-Bruce, S.9
Durairaj, R.10
Sun, Q.11
Mihai, G.12
Maiseyeu, A.13
Rajagopalan, S.14
-
169
-
-
80051752340
-
Acute DPP-4 inhibition modulates vascular tone through GLP-1 independent pathways
-
Shah Z, Pineda C, Kampfrath T, Maiseyeu A, Ying Z, Racoma I, Deiuliis J, Xu X, Sun Q, Moffatt-Bruce S, Villamena F, Rajagopalan S. Acute DPP-4 inhibition modulates vascular tone through GLP-1 independent pathways. Vasc Pharmacol 55: 2-9, 2011.
-
(2011)
Vasc Pharmacol
, vol.55
, pp. 2-9
-
-
Shah, Z.1
Pineda, C.2
Kampfrath, T.3
Maiseyeu, A.4
Ying, Z.5
Racoma, I.6
Deiuliis, J.7
Xu, X.8
Sun, Q.9
Moffatt-Bruce, S.10
Villamena, F.11
Rajagopalan, S.12
-
170
-
-
84867254999
-
Dipeptidyl peptidase-4 modulates left ventricular dysfunction in chronic heart failure via angiogenesis-dependent and-independent actions
-
Shigeta T, Aoyama M, Bando YK, Monji A, Mitsui T, Takatsu M, Cheng XW, Okumura T, Hirashiki A, Nagata K, Murohara T. Dipeptidyl peptidase-4 modulates left ventricular dysfunction in chronic heart failure via angiogenesis-dependent and-independent actions. Circulation 126: 1838-1851, 2012.
-
(2012)
Circulation
, vol.126
, pp. 1838-1851
-
-
Shigeta, T.1
Aoyama, M.2
Bando, Y.K.3
Monji, A.4
Mitsui, T.5
Takatsu, M.6
Cheng, X.W.7
Okumura, T.8
Hirashiki, A.9
Nagata, K.10
Murohara, T.11
-
171
-
-
79953213304
-
Diet-induced adipose tissue inflammation and liver steatosis are prevented by DPP-4 inhibition in diabetic mice
-
Shirakawa J, Fujii H, Ohnuma K, Sato K, Ito Y, Kaji M, Sakamoto E, Koganei M, Sasaki H, Nagashima Y, Amo K, Aoki K, Morimoto C, Takeda E, Terauchi Y. Diet-induced adipose tissue inflammation and liver steatosis are prevented by DPP-4 inhibition in diabetic mice. Diabetes 60: 1246-1257, 2011.
-
(2011)
Diabetes
, vol.60
, pp. 1246-1257
-
-
Shirakawa, J.1
Fujii, H.2
Ohnuma, K.3
Sato, K.4
Ito, Y.5
Kaji, M.6
Sakamoto, E.7
Koganei, M.8
Sasaki, H.9
Nagashima, Y.10
Amo, K.11
Aoki, K.12
Morimoto, C.13
Takeda, E.14
Terauchi, Y.15
-
172
-
-
33845293219
-
Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure
-
Sokos GG, Nikolaidis LA, Mankad S, Elahi D, Shannon RP. Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure. J Card Fail 12: 694-699, 2006.
-
(2006)
J Card Fail
, vol.12
, pp. 694-699
-
-
Sokos, G.G.1
Nikolaidis, L.A.2
Mankad, S.3
Elahi, D.4
Shannon, R.P.5
-
173
-
-
77956051448
-
Comparative effects of telmisartan, sitagliptin and metformin alone or in combination on obesity, insulin resistance, and liver and pancreas remodelling in C57BL/6 mice fed on a very high-fat diet
-
Souza-Mello V, Gregorio BM, Cardoso-de-Lemos FS, de Carvalho L, Aguila MB, Mandarim-de-Lacerda CA. Comparative effects of telmisartan, sitagliptin and metformin alone or in combination on obesity, insulin resistance, and liver and pancreas remodelling in C57BL/6 mice fed on a very high-fat diet. Clin Sci (Lond) 119: 239-250, 2010.
-
(2010)
Clin Sci (Lond)
, vol.119
, pp. 239-250
-
-
Souza-Mello, V.1
Gregorio, B.M.2
Cardoso-de-Lemos, F.S.3
de Carvalho, L.4
Aguila, M.B.5
Mandarim-de-Lacerda, C.A.6
-
174
-
-
79959854855
-
Pancreatic ultrastructural enhancement due to telmisartan plus sitagliptin treatment in diet-induced obese C57BL/6 mice
-
Souza-Mello V, Gregorio BM, Relvas-Lucas B, da Silva Faria T, Aguila MB, Mandarim-de-Lacerda CA. Pancreatic ultrastructural enhancement due to telmisartan plus sitagliptin treatment in diet-induced obese C57BL/6 mice. Pancreas 40: 715-722, 2011.
-
(2011)
Pancreas
, vol.40
, pp. 715-722
-
-
Souza-Mello, V.1
Gregorio, B.M.2
Relvas-Lucas, B.3
da Silva Faria, T.4
Aguila, M.B.5
Mandarim-de-Lacerda, C.A.6
-
175
-
-
84876539915
-
Diabetes mellitus and vascular disease
-
Sowers JR. Diabetes mellitus and vascular disease. Hypertension 61: 943-947, 2013.
-
(2013)
Hypertension
, vol.61
, pp. 943-947
-
-
Sowers, J.R.1
-
177
-
-
84885572444
-
The influence of perivascular adipose tissue on vascular homeostasis
-
Szasz T, Bomfim GF, Webb RC. The influence of perivascular adipose tissue on vascular homeostasis. Vasc Health Risk Manag 9: 105-116, 2013.
-
(2013)
Vasc Health Risk Manag
, vol.9
, pp. 105-116
-
-
Szasz, T.1
Bomfim, G.F.2
Webb, R.C.3
-
178
-
-
80051785333
-
DPP-4 (CD26) inhibitor alogliptin inhibits atherosclerosis in diabetic apolipoprotein E-deficient mice
-
Ta NN, Schuyler CA, Li Y, Lopes-Virella MF, Huang Y. DPP-4 (CD26) inhibitor alogliptin inhibits atherosclerosis in diabetic apolipoprotein E-deficient mice. J Cardiovasc Pharmacol 58: 157-166, 2011.
-
(2011)
J Cardiovasc Pharmacol
, vol.58
, pp. 157-166
-
-
Ta, N.N.1
Schuyler, C.A.2
Li, Y.3
Lopes-Virella, M.F.4
Huang, Y.5
-
179
-
-
0037180517
-
Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures
-
Tepper OM, Galiano RD, Capla JM, Kalka C, Gagne PJ, Jacobowitz GR, Levine JP, Gurtner GC. Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 106: 2781-2786, 2002.
-
(2002)
Circulation
, vol.106
, pp. 2781-2786
-
-
Tepper, O.M.1
Galiano, R.D.2
Capla, J.M.3
Kalka, C.4
Gagne, P.J.5
Jacobowitz, G.R.6
Levine, J.P.7
Gurtner, G.C.8
-
180
-
-
41149118550
-
(R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazoli n-2-ylmethyl)-3,7-dihydro-purine-2,6-dione (BI 1356), a novel xanthine-based dipeptidyl peptidase 4 inhibitor, has a superior potency and longer duration of action compared with other dipeptidyl peptidase-4 inhibitors
-
Thomas L, Eckhardt M, Langkopf E, Tadayyon M, Himmelsbach F, Mark M. (R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazoli n-2-ylmethyl)-3,7-dihydro-purine-2,6-dione (BI 1356), a novel xanthine-based dipeptidyl peptidase 4 inhibitor, has a superior potency and longer duration of action compared with other dipeptidyl peptidase-4 inhibitors. J Pharmacol Exp Ther 325: 175-182, 2008.
-
(2008)
J Pharmacol Exp Ther
, vol.325
, pp. 175-182
-
-
Thomas, L.1
Eckhardt, M.2
Langkopf, E.3
Tadayyon, M.4
Himmelsbach, F.5
Mark, M.6
-
181
-
-
79951933599
-
Effect of sitagliptin therapy on postprandial lipoprotein levels in patients with type 2 diabetes
-
Tremblay AJ, Lamarche B, Deacon CF, Weisnagel SJ, Couture P. Effect of sitagliptin therapy on postprandial lipoprotein levels in patients with type 2 diabetes. Diabetes Obes Metab 13: 366-373, 2011.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 366-373
-
-
Tremblay, A.J.1
Lamarche, B.2
Deacon, C.F.3
Weisnagel, S.J.4
Couture, P.5
-
182
-
-
84860204551
-
Cardiovascular biology of the incretin system
-
Ussher JR, Drucker DJ. Cardiovascular biology of the incretin system. Endocr Rev 33: 187-215, 2012.
-
(2012)
Endocr Rev
, vol.33
, pp. 187-215
-
-
Ussher, J.R.1
Drucker, D.J.2
-
183
-
-
83455230038
-
Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes
-
van Poppel PC, Netea MG, Smits P, Tack CJ. Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes. Diabetes Care 34: 2072-2077, 2011.
-
(2011)
Diabetes Care
, vol.34
, pp. 2072-2077
-
-
van Poppel, P.C.1
Netea, M.G.2
Smits, P.3
Tack, C.J.4
-
184
-
-
52649174353
-
Early cardiac abnormalities in obese children: Importance of obesity per se versus associated cardiovascular risk factors
-
Van Putte-Katier N, Rooman RP, Haas L, Verhulst SL, Desager KN, Ramet J, Suys BE. Early cardiac abnormalities in obese children: importance of obesity per se versus associated cardiovascular risk factors. Pediatr Res 64: 205-209, 2008.
-
(2008)
Pediatr Res
, vol.64
, pp. 205-209
-
-
Van Putte-Katier, N.1
Rooman, R.P.2
Haas, L.3
Verhulst, S.L.4
Desager, K.N.5
Ramet, J.6
Suys, B.E.7
-
185
-
-
84875907876
-
Efficacy and safety of linagliptin in type 2 diabetes subjects at high risk for renal and cardiovascular disease: A pooled analysis of six phase III clinical trials
-
von Eynatten M, Gong Y, Emser A, Woerle HJ. Efficacy and safety of linagliptin in type 2 diabetes subjects at high risk for renal and cardiovascular disease: a pooled analysis of six phase III clinical trials. Cardiovasc Diabetol 12: 60, 2013.
-
(2013)
Cardiovasc Diabetol
, vol.12
, pp. 60
-
-
von Eynatten, M.1
Gong, Y.2
Emser, A.3
Woerle, H.J.4
-
186
-
-
84891609410
-
Arterial stiffening precedes systolic hypertension in diet-induced obesity
-
Weisbrod RM, Shiang T, Al Sayah L, Fry JL, Bajpai S, Reinhart-King CA, Lob HE, Santhanam L, Mitchell G, Cohen RA, Seta F. Arterial stiffening precedes systolic hypertension in diet-induced obesity. Hypertension 62: 1105-1110, 2013.
-
(2013)
Hypertension
, vol.62
, pp. 1105-1110
-
-
Weisbrod, R.M.1
Shiang, T.2
Al Sayah, L.3
Fry, J.L.4
Bajpai, S.5
Reinhart-King, C.A.6
Lob, H.E.7
Santhanam, L.8
Mitchell, G.9
Cohen, R.A.10
Seta, F.11
-
187
-
-
24344442873
-
Circulating endothelial progenitor cells and cardiovascular outcomes
-
Werner N, Kosiol S, Schiegl T, Ahlers P, Walenta K, Link A, Bohm M, Nickenig G. Circulating endothelial progenitor cells and cardiovascular outcomes. N Engl J Med 353: 999-1007, 2005.
-
(2005)
N Engl J Med
, vol.353
, pp. 999-1007
-
-
Werner, N.1
Kosiol, S.2
Schiegl, T.3
Ahlers, P.4
Walenta, K.5
Link, A.6
Bohm, M.7
Nickenig, G.8
-
188
-
-
82855173012
-
Diabetic Cardiovascular Disease Predicts Chronic Kidney Disease Awareness in the Kidney Early Evaluation Program
-
on behalf of the Kidney Early Evaluation Program Investigators
-
Whaley-Connell A, Bomback AS, McFarlane SI, Li S, Roberts T, Chen SC, Collins AJ, Norris K, Bakris GL, Sowers JR, McCullough PA; on behalf of the Kidney Early Evaluation Program Investigators. Diabetic Cardiovascular Disease Predicts Chronic Kidney Disease Awareness in the Kidney Early Evaluation Program. Cardiorenal Med 1: 45-52, 2011.
-
(2011)
Cardiorenal Med
, vol.1
, pp. 45-52
-
-
Whaley-Connell, A.1
Bomback, A.S.2
McFarlane, S.I.3
Li, S.4
Roberts, T.5
Chen, S.C.6
Collins, A.J.7
Norris, K.8
Bakris, G.L.9
Sowers, J.R.10
McCullough, P.A.11
-
189
-
-
77649291571
-
Aldosterone: Role in the cardiometabolic syndrome and resistant hypertension
-
Whaley-Connell A, Johnson MS, Sowers JR. Aldosterone: role in the cardiometabolic syndrome and resistant hypertension. Prog Cardiovasc Dis 52: 401-409, 2010.
-
(2010)
Prog Cardiovasc Dis
, vol.52
, pp. 401-409
-
-
Whaley-Connell, A.1
Johnson, M.S.2
Sowers, J.R.3
-
190
-
-
84883745765
-
Alogliptin after acute coronary syndrome in patients with type 2 diabetes
-
EXAMINE Investigators
-
White WB, Cannon CP, Heller SR, Nissen SE, Bergenstal RM, Bakris GL, Perez AT, Fleck PR, Mehta CR, Kupfer S, Wilson C, Cushman WC, Zannad F; EXAMINE Investigators. Alogliptin after acute coronary syndrome in patients with type 2 diabetes. N Engl J Med 369: 1327-1335, 2013.
-
(2013)
N Engl J Med
, vol.369
, pp. 1327-1335
-
-
White, W.B.1
Cannon, C.P.2
Heller, S.R.3
Nissen, S.E.4
Bergenstal, R.M.5
Bakris, G.L.6
Perez, A.T.7
Fleck, P.R.8
Mehta, C.R.9
Kupfer, S.10
Wilson, C.11
Cushman, W.C.12
Zannad, F.13
-
191
-
-
84878939138
-
Cardiovascular safety of the dipetidyl peptidase-4 inhibitor alogliptin in type 2 diabetes mellitus
-
White WB, Pratley R, Fleck P, Munsaka M, Hisada M, Wilson C, Menon V. Cardiovascular safety of the dipetidyl peptidase-4 inhibitor alogliptin in type 2 diabetes mellitus. Diabetes Obes Metab 15: 668-673, 2013.
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 668-673
-
-
White, W.B.1
Pratley, R.2
Fleck, P.3
Munsaka, M.4
Hisada, M.5
Wilson, C.6
Menon, V.7
-
192
-
-
84904007147
-
Dipeptidyl peptidase-4 inhibitors and cardiovascular outcomes: Meta-analysis of randomized clinical trials with 55,141 participants
-
Apr 21. doi:10.1111/ 1755-5922.12075. [Epub ahead of print]
-
Wu S, Hopper I, Skiba M, Krum H. Dipeptidyl peptidase-4 inhibitors and cardiovascular outcomes: Meta-analysis of randomized clinical trials with 55,141 participants. Cardiovasc Ther. 2014 Apr 21. doi:10.1111/ 1755-5922.12075. [Epub ahead of print].
-
(2014)
Cardiovasc Ther.
-
-
Wu, S.1
Hopper, I.2
Skiba, M.3
Krum, H.4
-
193
-
-
77950898257
-
The RAGE axis: A fundamental mechanism signaling danger to the vulnerable vasculature
-
Yan SF, Ramasamy R, Schmidt AM. The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature. Circ Res 106: 842-853, 2010.
-
(2010)
Circ Res
, vol.106
, pp. 842-853
-
-
Yan, S.F.1
Ramasamy, R.2
Schmidt, A.M.3
-
194
-
-
65349167787
-
The receptor for advanced glycation endproducts (RAGE) and cardiovascular disease
-
Yan SF, Ramasamy R, Schmidt AM. The receptor for advanced glycation endproducts (RAGE) and cardiovascular disease. Expert Rev Mol Med 11: e9, 2009.
-
(2009)
Expert Rev Mol Med
, vol.11
-
-
Yan, S.F.1
Ramasamy, R.2
Schmidt, A.M.3
-
195
-
-
34447103388
-
Increase in DPP-IV in the intestine, liver and kidney of the rat treated with high fat diet and streptozotocin
-
Yang J, Campitelli J, Hu G, Lin Y, Luo J, Xue C. Increase in DPP-IV in the intestine, liver and kidney of the rat treated with high fat diet and streptozotocin. Life Sci 81: 272-279, 2007.
-
(2007)
Life Sci
, vol.81
, pp. 272-279
-
-
Yang, J.1
Campitelli, J.2
Hu, G.3
Lin, Y.4
Luo, J.5
Xue, C.6
-
196
-
-
70350328161
-
Dipeptidyl peptidase inhibitors, an emerging drug class for inflammatory disease?
-
Yazbeck R, Howarth GS, Abbott CA. Dipeptidyl peptidase inhibitors, an emerging drug class for inflammatory disease? Trends Pharmacol Sci 30: 600-607, 2009.
-
(2009)
Trends Pharmacol Sci
, vol.30
, pp. 600-607
-
-
Yazbeck, R.1
Howarth, G.S.2
Abbott, C.A.3
-
197
-
-
77951812608
-
The myocardial infarct size-limiting effect of sitagliptin is PKA-dependent, whereas the protective effect of pioglitazone is partially dependent on PKA
-
Ye Y, Keyes KT, Zhang C, Perez-Polo JR, Lin Y, Birnbaum Y. The myocardial infarct size-limiting effect of sitagliptin is PKA-dependent, whereas the protective effect of pioglitazone is partially dependent on PKA. Am J Physiol Heart Circ Physiol 298: H1454-H1465, 2010.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
-
-
Ye, Y.1
Keyes, K.T.2
Zhang, C.3
Perez-Polo, J.R.4
Lin, Y.5
Birnbaum, Y.6
-
198
-
-
80053358548
-
Early and late effects of the DPP-4 inhibitor vildagliptin in a rat model of postmyocardial infarction heart failure
-
Yin M, Sillje HH, Meissner M, van Gilst WH, de Boer RA. Early and late effects of the DPP-4 inhibitor vildagliptin in a rat model of postmyocardial infarction heart failure. Cardiovasc Diabetol 10: 85, 2011.
-
(2011)
Cardiovasc Diabetol
, vol.10
, pp. 85
-
-
Yin, M.1
Sillje, H.H.2
Meissner, M.3
van Gilst, W.H.4
de Boer, R.A.5
-
199
-
-
20244378531
-
Progressive attenuation of myocardial vascular endothelial growth factor expression is a seminal event in diabetic cardiomyopathy: Restoration of microvascular homeostasis and recovery of cardiac function in diabetic cardiomyopathy after replenishment of local vascular endothelial growth factor
-
Yoon YS, Uchida S, Masuo O, Cejna M, Park JS, Gwon HC, Kirchmair R, Bahlman F, Walter D, Curry C, Hanley A, Isner JM, Losordo DW. Progressive attenuation of myocardial vascular endothelial growth factor expression is a seminal event in diabetic cardiomyopathy: restoration of microvascular homeostasis and recovery of cardiac function in diabetic cardiomyopathy after replenishment of local vascular endothelial growth factor. Circulation 111: 2073-2085, 2005.
-
(2005)
Circulation
, vol.111
, pp. 2073-2085
-
-
Yoon, Y.S.1
Uchida, S.2
Masuo, O.3
Cejna, M.4
Park, J.S.5
Gwon, H.C.6
Kirchmair, R.7
Bahlman, F.8
Walter, D.9
Curry, C.10
Hanley, A.11
Isner, J.M.12
Losordo, D.W.13
-
200
-
-
62949195390
-
Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction
-
Zaruba MM, Theiss HD, Vallaster M, Mehl U, Brunner S, David R, Fischer R, Krieg L, Hirsch E, Huber B, Nathan P, Israel L, Imhof A, Herbach N, Assmann G, Wanke R, Mueller-Hoecker J, Steinbeck G, Franz WM. Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction. Cell Stem Cell 4: 313-323, 2009.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 313-323
-
-
Zaruba, M.M.1
Theiss, H.D.2
Vallaster, M.3
Mehl, U.4
Brunner, S.5
David, R.6
Fischer, R.7
Krieg, L.8
Hirsch, E.9
Huber, B.10
Nathan, P.11
Israel, L.12
Imhof, A.13
Herbach, N.14
Assmann, G.15
Wanke, R.16
Mueller-Hoecker, J.17
Steinbeck, G.18
Franz, W.M.19
-
201
-
-
33646795007
-
Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts
-
Zhao T, Parikh P, Bhashyam S, Bolukoglu H, Poornima I, Shen YT, Shannon RP. Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts. J Pharmacol Exp Ther 317: 1106-1113, 2006.
-
(2006)
J Pharmacol Exp Ther
, vol.317
, pp. 1106-1113
-
-
Zhao, T.1
Parikh, P.2
Bhashyam, S.3
Bolukoglu, H.4
Poornima, I.5
Shen, Y.T.6
Shannon, R.P.7
-
202
-
-
84872424922
-
An emerging role of dipeptidyl peptidase 4 (DPP4) beyond glucose control: Potential implications in cardiovascular disease
-
Zhong J, Rao X, Rajagopalan S. An emerging role of dipeptidyl peptidase 4 (DPP4) beyond glucose control: potential implications in cardiovascular disease. Atherosclerosis 226: 305-314, 2013.
-
(2013)
Atherosclerosis
, vol.226
, pp. 305-314
-
-
Zhong, J.1
Rao, X.2
Rajagopalan, S.3
-
203
-
-
77950466818
-
Nebivolol improves diastolic dysfunction and myocardial tissue remodeling through reductions in oxidative stress in the Zucker Obese rat
-
Zhou X, Ma L, Habibi J, Whaley-Connel AT, Hayden MR, Tilmon RD, Brown AN, DeMarco VG, Sowers JR. Nebivolol improves diastolic dysfunction and myocardial tissue remodeling through reductions in oxidative stress in the Zucker Obese rat. Hypertension 55: 880-888, 2010.
-
(2010)
Hypertension
, vol.55
, pp. 880-888
-
-
Zhou, X.1
Ma, L.2
Habibi, J.3
Whaley-Connel, A.T.4
Hayden, M.R.5
Tilmon, R.D.6
Brown, A.N.7
DeMarco, V.G.8
Sowers, J.R.9
-
205
-
-
33745684904
-
Mitochondrial ROS-induced ROS release: An update and review
-
Zorov DB, Juhaszova M, Sollott SJ. Mitochondrial ROS-induced ROS release: an update and review. Biochim Biophys Acta 1757: 509-517, 2006.
-
(2006)
Biochim Biophys Acta
, vol.1757
, pp. 509-517
-
-
Zorov, D.B.1
Juhaszova, M.2
Sollott, S.J.3
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