-
2
-
-
80053065245
-
The threat of artemisinin- resistant malaria
-
PMID: 21992120
-
Dondorp AM, Fairhurst RM, Slutsker L, Macarthur JR, Breman JG, Guerin PJ, et al. The threat of artemisinin- resistant malaria. N Engl J Med. 2011; 365(12):1073-5. doi: 10.1056/NEJMp1108322 PMID: 21992120.
-
(2011)
N Engl J Med
, vol.365
, Issue.12
, pp. 1073-1075
-
-
Dondorp, A.M.1
Fairhurst, R.M.2
Slutsker, L.3
Macarthur, J.R.4
Breman, J.G.5
Guerin, P.J.6
-
3
-
-
84904892931
-
Spread of artemisinin resistance in Plasmodium falciparum malaria
-
PMID: 25075834
-
Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S, et al. Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2014; 371(5):411-23. doi: 10.1056/NEJMoa1314981 PMID: 25075834.
-
(2014)
N Engl J Med
, vol.371
, Issue.5
, pp. 411-423
-
-
Ashley, E.A.1
Dhorda, M.2
Fairhurst, R.M.3
Amaratunga, C.4
Lim, P.5
Suon, S.6
-
4
-
-
84860672426
-
Malaria drug resistance: New observations and developments
-
PMID: 22023447
-
Sa JM, Chong JL, Wellems TE. Malaria drug resistance: new observations and developments. Essays Biochem. 2011; 51:137-60. doi: 10.1042/bse0510137 PMID: 22023447.
-
(2011)
Essays Biochem
, vol.51
, pp. 137-160
-
-
Sa, J.M.1
Chong, J.L.2
Wellems, T.E.3
-
5
-
-
84927799735
-
Antimalarial drug resistance in Africa: Key lessons for the future
-
PMID: 25891142
-
Takala-Harrison S, Laufer MK. Antimalarial drug resistance in Africa: key lessons for the future. Ann N Y Acad Sci. 2015; 1342:62-7. doi: 10.1111/nyas.12766 PMID: 25891142.
-
(2015)
Ann N y Acad Sci
, vol.1342
, pp. 62-67
-
-
Takala-Harrison, S.1
Laufer, M.K.2
-
6
-
-
77950435762
-
Origin and evolution of sulfadoxine resistant Plasmodium falciparum
-
PMID: 20360965
-
Vinayak S, Alam MT, Mixson-Hayden T, McCollum AM, Sem R, Shah NK, et al. Origin and evolution of sulfadoxine resistant Plasmodium falciparum. PLoS Pathog. 2010; 6(3):e1000830. doi: 10.1371/journal.ppat.1000830 PMID: 20360965.
-
(2010)
PLoS Pathog
, vol.6
, Issue.3
, pp. e1000830
-
-
Vinayak, S.1
Alam, M.T.2
Mixson-Hayden, T.3
McCollum, A.M.4
Sem, R.5
Shah, N.K.6
-
7
-
-
84884414547
-
Monitoring antifolate resistance in intermittent preventive therapy for malaria
-
PMID: 23948432
-
Venkatesan M, Alifrangis M, Roper C, Plowe CV. Monitoring antifolate resistance in intermittent preventive therapy for malaria. Trends Parasitol. 2013; 29(10):497-504. doi: 10.1016/j.pt.2013.07.008 PMID: 23948432.
-
(2013)
Trends Parasitol
, vol.29
, Issue.10
, pp. 497-504
-
-
Venkatesan, M.1
Alifrangis, M.2
Roper, C.3
Plowe, C.V.4
-
8
-
-
0030829371
-
Variations in frequencies of drug resistance in Plasmodium falciparum
-
PMID: 9256492
-
Rathod PK, McErlean T, Lee PC. Variations in frequencies of drug resistance in Plasmodium falciparum. Proc Natl Acad Sci U S A. 1997; 94(17):9389-93. PMID: 9256492.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, Issue.17
, pp. 9389-9393
-
-
Rathod, P.K.1
McErlean, T.2
Lee, P.C.3
-
9
-
-
84878715473
-
Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia
-
PMID: 23624527
-
Miotto O, Almagro-Garcia J, Manske M, Macinnis B, Campino S, Rockett KA, et al. Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia. Nat Genet. 2013; 45(6):648-55. doi: 10. 1038/ng.2624 PMID: 23624527.
-
(2013)
Nat Genet
, vol.45
, Issue.6
, pp. 648-655
-
-
Miotto, O.1
Almagro-Garcia, J.2
Manske, M.3
Macinnis, B.4
Campino, S.5
Rockett, K.A.6
-
10
-
-
84874788696
-
Mitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen families
-
PMID: 23408914
-
Bopp SE, Manary MJ, Bright AT, Johnston GL, Dharia NV, Luna FL, et al. Mitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen families. PLoS Genet. 2013; 9(2):e1003293. doi: 10.1371/journal.pgen.1003293 PMID: 23408914.
-
(2013)
PLoS Genet
, vol.9
, Issue.2
, pp. e1003293
-
-
Bopp, S.E.1
Manary, M.J.2
Bright, A.T.3
Johnston, G.L.4
Dharia, N.V.5
Luna, F.L.6
-
11
-
-
84919667206
-
Generation of antigenic diversity in Plasmodium falciparum by structured rearrangement of Var genes during mitosis
-
PMID: 25521112
-
Claessens A, Hamilton WL, Kekre M, Otto TD, Faizullabhoy A, Rayner JC, et al. Generation of antigenic diversity in Plasmodium falciparum by structured rearrangement of Var genes during mitosis. PLoS Genet. 2014; 10(12):e1004812. doi: 10.1371/journal.pgen.1004812 PMID: 25521112.
-
(2014)
PLoS Genet
, vol.10
, Issue.12
, pp. e1004812
-
-
Claessens, A.1
Hamilton, W.L.2
Kekre, M.3
Otto, T.D.4
Faizullabhoy, A.5
Rayner, J.C.6
-
12
-
-
84921528358
-
Plasmodium falciparum field isolates from areas of repeated emergence of drug resistant malaria show no evidence of hypermutator phenotype
-
PMID: 25514047
-
Brown TS, Jacob CG, Silva JC, Takala-Harrison S, Djimde A, Dondorp AM, et al. Plasmodium falciparum field isolates from areas of repeated emergence of drug resistant malaria show no evidence of hypermutator phenotype. Infect Genet Evol. 2015; 30:318-22. doi: 10.1016/j.meegid.2014.12.010 PMID: 25514047.
-
(2015)
Infect Genet Evol
, vol.30
, pp. 318-322
-
-
Brown, T.S.1
Jacob, C.G.2
Silva, J.C.3
Takala-Harrison, S.4
Djimde, A.5
Dondorp, A.M.6
-
13
-
-
3843140450
-
Polymorphic mutation frequencies in Escherichia coli: Emergence of weak mutators in clinical isolates
-
PMID: 15292159
-
Baquero MR, Nilsson AI, Turrientes Mdel C, Sandvang D, Galan JC, Martinez JL, et al. Polymorphic mutation frequencies in Escherichia coli: emergence of weak mutators in clinical isolates. J Bacteriol. 2004; 186(16):5538-42. doi: 10.1128/JB.186.16.5538-5542.2004 PMID: 15292159.
-
(2004)
J Bacteriol
, vol.186
, Issue.16
, pp. 5538-5542
-
-
Baquero, M.R.1
Nilsson, A.I.2
Turrientes Mdel, C.3
Sandvang, D.4
Galan, J.C.5
Martinez, J.L.6
-
14
-
-
31544468664
-
Intermediate mutation frequencies favor evolution of multidrug resistance in Escherichia coli
-
PMID: 15965238
-
Denamur E, Tenaillon O, Deschamps C, Skurnik D, Ronco E, Gaillard JL, et al. Intermediate mutation frequencies favor evolution of multidrug resistance in Escherichia coli. Genetics. 2005; 171(2):825-7. doi: 10.1534/genetics.105.045526 PMID: 15965238.
-
(2005)
Genetics
, vol.171
, Issue.2
, pp. 825-827
-
-
Denamur, E.1
Tenaillon, O.2
Deschamps, C.3
Skurnik, D.4
Ronco, E.5
Gaillard, J.L.6
-
15
-
-
0141963052
-
Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage
-
PMID: 12972454
-
Gustafsson I, Sjolund M, Torell E, Johannesson M, Engstrand L, Cars O, et al. Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage. J Antimicrob Chemother. 2003; 52(4):645-50. doi: 10.1093/jac/dkg427 PMID: 12972454.
-
(2003)
J Antimicrob Chemother
, vol.52
, Issue.4
, pp. 645-650
-
-
Gustafsson, I.1
Sjolund, M.2
Torell, E.3
Johannesson, M.4
Engstrand, L.5
Cars, O.6
-
16
-
-
33749527062
-
Weak mutators can drive the evolution of fluoroquinolone resistance in Escherichia coli
-
PMID: 17005830
-
Orlen H, Hughes D. Weak mutators can drive the evolution of fluoroquinolone resistance in Escherichia coli. Antimicrob Agents Chemother. 2006; 50(10):3454-6. doi: 10.1128/AAC.00783-06 PMID: 17005830.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, Issue.10
, pp. 3454-3456
-
-
Orlen, H.1
Hughes, D.2
-
17
-
-
84888001845
-
Genome dynamics during experimental evolution
-
PMID: 24166031
-
Barrick JE, Lenski RE. Genome dynamics during experimental evolution. Nat Rev Genet. 2013; 14(12): 827-39. doi: 10.1038/nrg3564 PMID: 24166031.
-
(2013)
Nat Rev Genet
, vol.14
, Issue.12
, pp. 827-839
-
-
Barrick, J.E.1
Lenski, R.E.2
-
18
-
-
33646397599
-
Evolution of mutation rates in bacteria
-
PMID 16677295
-
Denamur E, Matic I. Evolution of mutation rates in bacteria. Mol Microbiol. 2006; 60(4):820-7. doi: 10. 1111/j.1365-2958.2006.05150.x PMID: 16677295.
-
(2006)
Mol Microbiol
, vol.60
, Issue.4
, pp. 820-827
-
-
Denamur, E.1
Matic, I.2
-
19
-
-
77956280420
-
Spiroindolones, a potent compound class for the treatment of malaria
-
PMID 20813948
-
Rottmann M, McNamara C, Yeung BK, Lee MC, Zou B, Russell B, et al. Spiroindolones, a potent compound class for the treatment of malaria. Science. 2010; 329(5996):1175-80. doi: 10.1126/science. 1193225 PMID: 20813948.
-
(2010)
Science
, vol.329
, Issue.5996
, pp. 1175-1180
-
-
Rottmann, M.1
McNamara, C.2
Yeung, B.K.3
Lee, M.C.4
Zou, B.5
Russell, B.6
-
20
-
-
84867917706
-
Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: A parasite clearance rate study
-
PMID: 22940027
-
Amaratunga C, Sreng S, Suon S, Phelps ES, Stepniewska K, Lim P, et al. Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study. Lancet Infect Dis. 2012; 12(11):851-8. doi: 10.1016/S1473-3099(12)70181-0 PMID: 22940027.
-
(2012)
Lancet Infect Dis
, vol.12
, Issue.11
, pp. 851-858
-
-
Amaratunga, C.1
Sreng, S.2
Suon, S.3
Phelps, E.S.4
Stepniewska, K.5
Lim, P.6
-
21
-
-
84921719133
-
K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates
-
PMID: 25502314
-
Straimer J, Gnadig NF, Witkowski B, Amaratunga C, Duru V, Ramadani AP, et al. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates. Science. 2015; 347(6220):428-31. doi: 10.1126/science.1260867 PMID: 25502314.
-
(2015)
Science
, vol.347
, Issue.6220
, pp. 428-431
-
-
Straimer, J.1
Gnadig, N.F.2
Witkowski, B.3
Amaratunga, C.4
Duru, V.5
Ramadani, A.P.6
-
22
-
-
0032407858
-
Cycloguanil and its parent compound proguanil demonstrate distinct activities against Plasmodium falciparum malaria parasites transformed with human dihydrofolate reductase
-
PMID: 9855645
-
Fidock DA, Nomura T, Wellems TE. Cycloguanil and its parent compound proguanil demonstrate distinct activities against Plasmodium falciparum malaria parasites transformed with human dihydrofolate reductase. Mol Pharmacol. 1998; 54(6):1140-7. PMID: 9855645.
-
(1998)
Mol Pharmacol
, vol.54
, Issue.6
, pp. 1140-1147
-
-
Fidock, D.A.1
Nomura, T.2
Wellems, T.E.3
-
23
-
-
23744435838
-
Pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum
-
PMID: 16091034
-
Sidhu AB, Valderramos SG, Fidock DA. pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum. Mol Microbiol. 2005; 57(4): 913-26. doi: 10.1111/j.1365-2958.2005.04729.x PMID: 16091034.
-
(2005)
Mol Microbiol
, vol.57
, Issue.4
, pp. 913-926
-
-
Sidhu, A.B.1
Valderramos, S.G.2
Fidock, D.A.3
-
24
-
-
0031171365
-
Plasmodium falciparum: A simple, rapid method for detecting parasite clones in microtiter plates
-
PMID: 9207746
-
Goodyer ID, Taraschi TF. Plasmodium falciparum: a simple, rapid method for detecting parasite clones in microtiter plates. Exp Parasitol. 1997; 86(2):158-60. doi: 10.1006/expr.1997.4156 PMID: 9207746.
-
(1997)
Exp Parasitol
, vol.86
, Issue.2
, pp. 158-160
-
-
Goodyer, I.D.1
Taraschi, T.F.2
-
25
-
-
80053912304
-
Identifying apicoplast-targeting antimalarials using highthroughput compatible approaches
-
PMID: 21746861
-
Ekland EH, Schneider J, Fidock DA. Identifying apicoplast-targeting antimalarials using highthroughput compatible approaches. FASEB J. 2011; 25(10):3583-93. doi: 10.1096/fj.11-187401 PMID: 21746861.
-
(2011)
FASEB J
, vol.25
, Issue.10
, pp. 3583-3593
-
-
Ekland, E.H.1
Schneider, J.2
Fidock, D.A.3
-
26
-
-
66349117823
-
Fluctuation analysis CalculatOR: A web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis
-
PMID: 19369502
-
Hall BM, Ma CX, Liang P, Singh KK. Fluctuation analysis CalculatOR: a web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis. Bioinformatics. 2009; 25(12):1564-5. doi: 10.1093/bioinformatics/btp253 PMID: 19369502.
-
(2009)
Bioinformatics
, vol.25
, Issue.12
, pp. 1564-1565
-
-
Hall, B.M.1
Ma, C.X.2
Liang, P.3
Singh, K.K.4
-
27
-
-
33745211644
-
Methods for determining spontaneous mutation rates
-
PMID: 16793403
-
Foster PL. Methods for determining spontaneous mutation rates. Methods Enzymol. 2006; 409: 195-213. doi: 10.1016/S0076-6879(05)09012-9 PMID: 16793403.
-
(2006)
Methods Enzymol
, vol.409
, pp. 195-213
-
-
Foster, P.L.1
-
28
-
-
0034809479
-
Spontaneous frameshift mutations in Saccharomyces cerevisiae: Accumulation during DNA replication and removal by proofreading and mismatch repair activities
-
PMID: 11560887
-
Greene CN, Jinks-Robertson S. Spontaneous frameshift mutations in Saccharomyces cerevisiae: accumulation during DNA replication and removal by proofreading and mismatch repair activities. Genetics. 2001; 159(1):65-75. PMID: 11560887.
-
(2001)
Genetics
, vol.159
, Issue.1
, pp. 65-75
-
-
Greene, C.N.1
Jinks-Robertson, S.2
-
29
-
-
46249109337
-
Incompatibilities involving yeast mismatch repair genes: A role for genetic modifiers and implications for disease penetrance and variation in genomic mutation rates
-
PMID: 18566663
-
Demogines A, Wong A, Aquadro C, Alani E. Incompatibilities involving yeast mismatch repair genes: a role for genetic modifiers and implications for disease penetrance and variation in genomic mutation rates. PLoS Genet. 2008; 4(6):e1000103. doi: 10.1371/journal.pgen.1000103 PMID: 18566663.
-
(2008)
PLoS Genet
, vol.4
, Issue.6
, pp. e1000103
-
-
Demogines, A.1
Wong, A.2
Aquadro, C.3
Alani, E.4
-
30
-
-
0034958793
-
Exo1-dependent mutator mutations: Model system for studying functional interactions in mismatch repair
-
PMID: 11438669
-
Amin NS, Nguyen MN, Oh S, Kolodner RD. exo1-dependent mutator mutations: model system for studying functional interactions in mismatch repair. Mol Cell Biol. 2001; 21(15):5142-55. doi: 10.1128/MCB.21.15.5142-5155.2001 PMID: 11438669.
-
(2001)
Mol Cell Biol
, vol.21
, Issue.15
, pp. 5142-5155
-
-
Amin, N.S.1
Nguyen, M.N.2
Oh, S.3
Kolodner, R.D.4
-
31
-
-
0001641514
-
Mutations of bacteria from virus sensitivity to virus resistance
-
PMID: 17247100
-
Luria SE, Delbruck M. Mutations of bacteria from virus sensitivity to virus resistance. Genetics. 1943; 28(6):491-511. PMID: 17247100.
-
(1943)
Genetics
, vol.28
, Issue.6
, pp. 491-511
-
-
Luria, S.E.1
Delbruck, M.2
-
32
-
-
0034006621
-
Determining mutation rates in bacterial populations
-
PMID: 10610800
-
Rosche WA, Foster PL. Determining mutation rates in bacterial populations. Methods. 2000; 20(1): 4-17. doi: 10.1006/meth.1999.0901 PMID: 10610800.
-
(2000)
Methods
, vol.20
, Issue.1
, pp. 4-17
-
-
Rosche, W.A.1
Foster, P.L.2
-
33
-
-
84944441631
-
Supporting malaria elimination with 21st century antimalarial agent drug discovery
-
PMID: 26103616
-
Diagana TT. Supporting malaria elimination with 21st century antimalarial agent drug discovery. Drug Discov Today. 2015; 20(10):1265-70. doi: 10.1016/j.drudis.2015.06.009 PMID: 26103616.
-
(2015)
Drug Discov Today
, vol.20
, Issue.10
, pp. 1265-1270
-
-
Diagana, T.T.1
-
34
-
-
84873901917
-
Na(+) regulation in the malaria parasite Plasmodium falciparum involves the cation ATPase PfATP4 and is a target of the spiroindolone antimalarials
-
PMID: 23414762
-
Spillman NJ, Allen RJ, McNamara CW, Yeung BK, Winzeler EA, Diagana TT, et al. Na(+) regulation in the malaria parasite Plasmodium falciparum involves the cation ATPase PfATP4 and is a target of the spiroindolone antimalarials. Cell Host Microbe. 2013; 13(2):227-37. doi: 10.1016/j.chom.2012.12.006 PMID: 23414762.
-
(2013)
Cell Host Microbe
, vol.13
, Issue.2
, pp. 227-237
-
-
Spillman, N.J.1
Allen, R.J.2
McNamara, C.W.3
Yeung, B.K.4
Winzeler, E.A.5
Diagana, T.T.6
-
35
-
-
84919363336
-
(+-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium
-
PMID: 25453091
-
Jimenez-Diaz MB, Ebert D, Salinas Y, Pradhan A, Lehane AM, Myrand-Lapierre ME, et al. (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium. Proc Natl Acad Sci U S A. 2014; 111(50):E5455-62. doi: 10.1073/pnas.1414221111 PMID: 25453091.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.50
, pp. E5455-E5462
-
-
Jimenez-Diaz, M.B.1
Ebert, D.2
Salinas, Y.3
Pradhan, A.4
Lehane, A.M.5
Myrand-Lapierre, M.E.6
-
36
-
-
84916599750
-
Diverse chemotypes disrupt ion homeostasis in the malaria parasite
-
PMID: 25145582
-
Lehane AM, Ridgway MC, Baker E, Kirk K. Diverse chemotypes disrupt ion homeostasis in the malaria parasite. Mol Microbiol. 2014; 94(2):327-39. doi: 10.1111/mmi.12765 PMID: 25145582.
-
(2014)
Mol Microbiol
, vol.94
, Issue.2
, pp. 327-339
-
-
Lehane, A.M.1
Ridgway, M.C.2
Baker, E.3
Kirk, K.4
-
37
-
-
84904909454
-
Spiroindolone KAE609 for falciparum and vivax malaria
-
PMID: 25075833
-
White NJ, Pukrittayakamee S, Phyo AP, Rueangweerayut R, Nosten F, Jittamala P, et al. Spiroindolone KAE609 for falciparum and vivax malaria. N Engl J Med. 2014; 371(5):403-10. doi: 10.1056/NEJMoa1315860 PMID: 25075833.
-
(2014)
N Engl J Med
, vol.371
, Issue.5
, pp. 403-410
-
-
White, N.J.1
Pukrittayakamee, S.2
Phyo, A.P.3
Rueangweerayut, R.4
Nosten, F.5
Jittamala, P.6
-
38
-
-
0037364995
-
Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility
-
PMID: 12629043
-
Wei K, Clark AB, Wong E, Kane MF, Mazur DJ, Parris T, et al. Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility. Genes Dev. 2003; 17(5):603-14. doi: 10.1101/gad.1060603 PMID: 12629043.
-
(2003)
Genes Dev
, vol.17
, Issue.5
, pp. 603-614
-
-
Wei, K.1
Clark, A.B.2
Wong, E.3
Kane, M.F.4
Mazur, D.J.5
Parris, T.6
-
39
-
-
0021028710
-
Plasmodium falciparum: Effect of time in continuous culture on binding to human endothelial cells and amelanotic melanoma cells
-
PMID: 6352321
-
Udeinya IJ, Graves PM, Carter R, Aikawa M, Miller LH. Plasmodium falciparum: effect of time in continuous culture on binding to human endothelial cells and amelanotic melanoma cells. Exp Parasitol. 1983; 56(2):207-14. PMID: 6352321.
-
(1983)
Exp Parasitol
, vol.56
, Issue.2
, pp. 207-214
-
-
Udeinya, I.J.1
Graves, P.M.2
Carter, R.3
Aikawa, M.4
Miller, L.H.5
-
40
-
-
84867653932
-
Malarial dihydrofolate reductase as a paradigm for drug development against a resistance- compromised target
-
PMID 23035243
-
Yuthavong Y, Tarnchompoo B, Vilaivan T, Chitnumsub P, Kamchonwongpaisan S, Charman SA, et al. Malarial dihydrofolate reductase as a paradigm for drug development against a resistance- compromised target. Proc Natl Acad Sci U S A. 2012; 109(42):16823-8. doi: 10.1073/pnas.1204556109 PMID: 23035243.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.42
, pp. 16823-16828
-
-
Yuthavong, Y.1
Tarnchompoo, B.2
Vilaivan, T.3
Chitnumsub, P.4
Kamchonwongpaisan, S.5
Charman, S.A.6
-
41
-
-
0024273546
-
Plasmodium falciparum: Induction of resistance to mefloquine in cloned strains by continuous drug exposure in vitro
-
PMID: 3056740
-
Oduola AM, Milhous WK, Weatherly NF, Bowdre JH, Desjardins RE. Plasmodium falciparum: induction of resistance to mefloquine in cloned strains by continuous drug exposure in vitro. Exp Parasitol. 1988; 67(2):354-60. PMID: 3056740.
-
(1988)
Exp Parasitol
, vol.67
, Issue.2
, pp. 354-360
-
-
Oduola, A.M.1
Milhous, W.K.2
Weatherly, N.F.3
Bowdre, J.H.4
Desjardins, R.E.5
-
43
-
-
0032781364
-
Resistance mutations reveal the atovaquone- binding domain of cytochrome b in malaria parasites
-
PMID: 10447880
-
Srivastava IK, Morrisey JM, Darrouzet E, Daldal F, Vaidya AB. Resistance mutations reveal the atovaquone- binding domain of cytochrome b in malaria parasites. Mol Microbiol. 1999; 33(4):704-11. PMID: 10447880.
-
(1999)
Mol Microbiol
, vol.33
, Issue.4
, pp. 704-711
-
-
Srivastava, I.K.1
Morrisey, J.M.2
Darrouzet, E.3
Daldal, F.4
Vaidya, A.B.5
-
44
-
-
0034130841
-
EXO1 and MSH6 are high-copy suppressors of conditional mutations in the MSH2 mismatch repair gene of Saccharomyces cerevisiae
-
PMID: 10835383
-
Sokolsky T, Alani E. EXO1 and MSH6 are high-copy suppressors of conditional mutations in the MSH2 mismatch repair gene of Saccharomyces cerevisiae. Genetics. 2000; 155(2):589-99. PMID: 10835383.
-
(2000)
Genetics
, vol.155
, Issue.2
, pp. 589-599
-
-
Sokolsky, T.1
Alani, E.2
-
45
-
-
84923327067
-
Mutations in the P-type cationtransporter ATPase 4, PfATP4, mediate resistance to both aminopyrazole and spiroindolone antimalarials
-
PMID: 25322084
-
Flannery EL, McNamara CW, Kim SW, Kato TS, Li F, Teng CH, et al. Mutations in the P-type cationtransporter ATPase 4, PfATP4, mediate resistance to both aminopyrazole and spiroindolone antimalarials. ACS Chem Biol. 2015; 10(2):413-20. doi: 10.1021/cb500616x PMID: 25322084.
-
(2015)
ACS Chem Biol
, vol.10
, Issue.2
, pp. 413-420
-
-
Flannery, E.L.1
McNamara, C.W.2
Kim, S.W.3
Kato, T.S.4
Li, F.5
Teng, C.H.6
-
46
-
-
84923311088
-
Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum
-
PMID: 25422853
-
Vaidya AB, Morrisey JM, Zhang Z, Das S, Daly TM, Otto TD, et al. Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum. Nat Commun. 2014; 5:5521. doi: 10.1038/ncomms6521 PMID: 25422853.
-
(2014)
Nat Commun
, vol.5
, pp. 5521
-
-
Vaidya, A.B.1
Morrisey, J.M.2
Zhang, Z.3
Das, S.4
Daly, T.M.5
Otto, T.D.6
-
47
-
-
84907916563
-
A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel antimalarial Spiroindolone KAE609 (Cipargamin) to assess its safety, tolerability, and pharmacokinetics in healthy adult volunteers
-
PMID: 25114127
-
Leong FJ, Li R, Jain JP, Lefevre G, Magnusson B, Diagana TT, et al. A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel antimalarial Spiroindolone KAE609 (Cipargamin) to assess its safety, tolerability, and pharmacokinetics in healthy adult volunteers. Antimicrob Agents Chemother. 2014; 58(10):6209-14. doi: 10.1128/AAC.03393-14 PMID: 25114127.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, Issue.10
, pp. 6209-6214
-
-
Leong, F.J.1
Li, R.2
Jain, J.P.3
Lefevre, G.4
Magnusson, B.5
Diagana, T.T.6
-
48
-
-
84876193944
-
Structure of the MutLalpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site
-
PMID: 23435383
-
Gueneau E, Dherin C, Legrand P, Tellier-Lebegue C, Gilquin B, Bonnesoeur P, et al. Structure of the MutLalpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site. Nat Struct Mol Biol. 2013; 20(4):461-8. doi: 10.1038/nsmb.2511 PMID: 23435383.
-
(2013)
Nat Struct Mol Biol
, vol.20
, Issue.4
, pp. 461-468
-
-
Gueneau, E.1
Dherin, C.2
Legrand, P.3
Tellier-Lebegue, C.4
Gilquin, B.5
Bonnesoeur, P.6
-
49
-
-
84876398399
-
DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae
-
PMID: 23547164
-
Boiteux S, Jinks-Robertson S. DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae. Genetics. 2013; 193(4):1025-64. doi: 10.1534/genetics.112.145219 PMID: 23547164.
-
(2013)
Genetics
, vol.193
, Issue.4
, pp. 1025-1064
-
-
Boiteux, S.1
Jinks-Robertson, S.2
-
50
-
-
34250344873
-
Functional analysis of human MLH1 variants using yeast and in vitro mismatch repair assays
-
PMID: 17510385
-
Takahashi M, Shimodaira H, Andreutti-Zaugg C, Iggo R, Kolodner RD, Ishioka C. Functional analysis of human MLH1 variants using yeast and in vitro mismatch repair assays. Cancer Res. 2007; 67(10): 4595-604. doi: 10.1158/0008-5472.CAN-06-3509 PMID: 17510385.
-
(2007)
Cancer Res
, vol.67
, Issue.10
, pp. 4595-4604
-
-
Takahashi, M.1
Shimodaira, H.2
Andreutti-Zaugg, C.3
Iggo, R.4
Kolodner, R.D.5
Ishioka, C.6
-
51
-
-
84961932806
-
Genomic epidemiology of artemisinin resistant malaria
-
PMID: 26943619
-
Malaria GENPfCP. Genomic epidemiology of artemisinin resistant malaria. Elife. 2016; 5. doi: 10.7554/eLife.08714 PMID: 26943619.
-
(2016)
Elife
, pp. 5
-
-
Malaria GENPfCP1
-
52
-
-
0033838152
-
Functional studies on the candidate ATPase domains of Saccharomyces cerevisiae MutLalpha
-
PMID: 10938116
-
Tran PT, Liskay RM. Functional studies on the candidate ATPase domains of Saccharomyces cerevisiae MutLalpha. Mol Cell Biol. 2000; 20(17):6390-8. PMID: 10938116.
-
(2000)
Mol Cell Biol
, vol.20
, Issue.17
, pp. 6390-6398
-
-
Tran, P.T.1
Liskay, R.M.2
-
53
-
-
84859714621
-
Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase
-
PMID: 22500800
-
Zakharyevich K, Tang S, Ma Y, Hunter N. Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase. Cell. 2012; 149(2):334-47. doi: 10.1016/j.cell.2012.03.023 PMID: 22500800.
-
(2012)
Cell
, vol.149
, Issue.2
, pp. 334-347
-
-
Zakharyevich, K.1
Tang, S.2
Ma, Y.3
Hunter, N.4
-
54
-
-
0033598817
-
Functional specificity of MutL homologs in yeast: Evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction
-
PMID: 10570173
-
Wang TF, Kleckner N, Hunter N. Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction. Proc Natl Acad Sci U S A. 1999; 96(24):13914-9. PMID: 10570173.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, Issue.24
, pp. 13914-13919
-
-
Wang, T.F.1
Kleckner, N.2
Hunter, N.3
-
55
-
-
84924080547
-
Genetic architecture of artemisinin-resistant Plasmodium falciparum
-
PMID 25599401
-
Miotto O, Amato R, Ashley EA, MacInnis B, Almagro-Garcia J, Amaratunga C, et al. Genetic architecture of artemisinin-resistant Plasmodium falciparum. Nat Genet. 2015; 47(3):226-34. doi: 10.1038/ng. 3189 PMID: 25599401.
-
(2015)
Nat Genet
, vol.47
, Issue.3
, pp. 226-234
-
-
Miotto, O.1
Amato, R.2
Ashley, E.A.3
MacInnis, B.4
Almagro-Garcia, J.5
Amaratunga, C.6
-
56
-
-
84891782659
-
Pfam: The protein families database
-
PMID: 24288371
-
Finn RD, Bateman A, Clements J, Coggill P, Eberhardt RY, Eddy SR, et al. Pfam: the protein families database. Nucleic Acids Res. 2014; 42(Database issue):D222-30. doi: 10.1093/nar/gkt1223 PMID: 24288371.
-
(2014)
Nucleic Acids Res
, vol.42
, Issue.DATABASE
, pp. D222-D230
-
-
Finn, R.D.1
Bateman, A.2
Clements, J.3
Coggill, P.4
Eberhardt, R.Y.5
Eddy, S.R.6
-
57
-
-
84979850726
-
I-TASSER server: New development for protein structure and function predictions
-
PMID: 25883148
-
Yang J, Zhang Y. I-TASSER server: new development for protein structure and function predictions. Nucleic Acids Res. 2015; 43(W1):W174-81. doi: 10.1093/nar/gkv342 PMID: 25883148.
-
(2015)
Nucleic Acids Res
, vol.43
, Issue.W1
, pp. W174-W181
-
-
Yang, J.1
Zhang, Y.2
-
58
-
-
84941220468
-
The malaria parasite cation ATPase PfATP4 and its role in the mechanism of action of a new arsenal of antimalarial drugs
-
PMID: 26401486
-
Spillman NJ, Kirk K. The malaria parasite cation ATPase PfATP4 and its role in the mechanism of action of a new arsenal of antimalarial drugs. Int J Parasitol Drugs Drug Resist. 2015; 5(3):149-62. doi: 10.1016/j.ijpddr.2015.07.001 PMID: 26401486.
-
(2015)
Int J Parasitol Drugs Drug Resist
, vol.5
, Issue.3
, pp. 149-162
-
-
Spillman, N.J.1
Kirk, K.2
|