Generation of Antigenic Diversity in Plasmodium falciparum by Structured Rearrangement of Var Genes During Mitosis

PLoS Genetics

Volumn 10, Issue 12, 2014, Pages

  Claessens, Antoine ^a   Hamilton, William L ^a   Kekre, Mihir ^a   Otto, Thomas D ^a   Faizullabhoy, Adnan ^a   Rayner, Julian C ^a   Kwiatkowski, Dominic ^a,b  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENIC VARIATION; ARTICLE; ASEXUAL REPRODUCTION; CONTROLLED STUDY; CROSSING OVER; ERYTHROCYTE; EXON; GENE; GENE DELETION; GENE DUPLICATION; GENE FREQUENCY; GENE REARRANGEMENT; GENE SEQUENCE; GENE TRANSLOCATION; GENETIC CODE; GENETIC RECOMBINATION; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMODIUM FALCIPARUM; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; STRAIN DIFFERENCE; VAR GENE; ALLELE; AMINO ACID SEQUENCE; CHROMOSOME MAP; CYTOLOGY; DNA SEQUENCE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MITOSIS; MOLECULAR CLONING; MOLECULAR GENETICS; PARASITOLOGY;

PLASMODIUM FALCIPARUM;

ERYTHROCYTE MEMBRANE PROTEIN 1, PLASMODIUM FALCIPARUM; PARASITE ANTIGEN; PROTOZOAL DNA; PROTOZOAL PROTEIN;

ALLELES; AMINO ACID SEQUENCE; ANTIGENIC VARIATION; ANTIGENS, PROTOZOAN; CHROMOSOME MAPPING; CLONING, MOLECULAR; DNA, PROTOZOAN; ERYTHROCYTES; EXONS; GENE EXPRESSION REGULATION; GENE REARRANGEMENT; HUMANS; MITOSIS; MOLECULAR SEQUENCE DATA; PLASMODIUM FALCIPARUM; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTOZOAN PROTEINS; SEQUENCE ANALYSIS, DNA;

EID: 84919667206     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004812     Document Type: Article

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