Age-dependent pancreatic gene regulation reveals mechanisms governing human β cell function

Cell Metabolism

Volumn 23, Issue 5, 2016, Pages 909-920

  Arda, H Efsun ^a   Li, Lingyu ^a   Tsai, Jennifer ^a   Torre, Eduardo A ^a   Rosli, Yenny ^a   Peiris, Heshan ^a   Spitale, Robert C ^a   Dai, Chunhua ^b   Gu, Xueying ^a   Qu, Kun ^a   Wang, Pei ^a   Wang, Jing ^a   Grompe, Markus ^c   Scharfmann, Raphael ^d   Snyder, Michael S ^a   Bottino, Rita ^e   Powers, Alvin C ^b,f   Chang, Howard Y ^a   Kim, Seung K ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d INSTITUT COCHIN   (France)

^e ALLEGHENY HEALTH NETWORK   (United States)

^f VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SIX2; TRANSCRIPTION FACTOR SIX3; UNCLASSIFIED DRUG; CHROMATIN; HOMEODOMAIN PROTEIN; TRANSCRIPTOME;

ACINAR CELL; ADULT; AGED; ARTICLE; CELL GROWTH; CELL ISOLATION; CELL MATURATION; CELL PROLIFERATION; CHILD; CHROMATIN; CONTROLLED STUDY; DIABETES MELLITUS; EXOCRINE CELL; GENE EXPRESSION; GENE IDENTIFICATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; INSULIN RELEASE; MIDDLE AGED; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PANCREATIC TISSUE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHOOL CHILD; YOUNG ADULT; AGING; CELL DIFFERENTIATION; CELL SEPARATION; CHROMATIN IMMUNOPRECIPITATION; GENE EXPRESSION REGULATION; GENETICS; HISTONE CODE; METABOLISM;

ADULT; AGING; CELL DIFFERENTIATION; CELL SEPARATION; CHILD; CHILD, PRESCHOOL; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; DIABETES MELLITUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HISTONE CODE; HOMEODOMAIN PROTEINS; HUMANS; INFANT; INSULIN-SECRETING CELLS; MIDDLE AGED; TRANSCRIPTION FACTORS; TRANSCRIPTOME; YOUNG ADULT;

EID: 84964576011     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2016.04.002     Document Type: Article

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