Human metapneumovirus small hydrophobic (SH) protein downregulates type I IFN pathway signaling by affecting STAT1 expression and phosphorylation

Virology

Volumn 494, Issue , 2016, Pages 248-256

  Hastings, Andrew K ^a   Amato, Katherine R ^a   Wen, Sherry C ^a   Peterson, Laura S ^a   Williams, John V ^b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

Interferon; Metapneumovirus; Paramyxovirus; Small hydrophobic protein

Indexed keywords

ALPHA INTERFERON; INTERFERON; PATTERN RECOGNITION RECEPTOR; SMALL HYDROPHOBIC PROTEIN; STAT1 PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRAL PROTEIN;

ANIMAL CELL; ARTICLE; CELL LYSATE; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; HUMAN METAPNEUMOVIRUS; HUMAN METAPNEUMOVIRUS INFECTION; INTERFERON PRODUCTION; NEGATIVE FEEDBACK; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; VERO CELL LINE; VIRUS IMMUNITY; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CELL LINE; CHLOROCEBUS AETHIOPS; GENE EXPRESSION REGULATION; GENETICS; HOST PATHOGEN INTERACTION; METABOLISM; METAPNEUMOVIRUS; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; CELL LINE; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; HUMANS; INTERFERON TYPE I; METAPNEUMOVIRUS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; VERO CELLS; VIRAL PROTEINS;

EID: 84964527045     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2016.04.022     Document Type: Article

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