Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling

Virology

Volumn 374, Issue 2, 2008, Pages 487-494

  Johnson, Karen E ^a   Song, Byeongwoon ^a   Knipe, David M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

HSV 1; ICP27; Interferon; STAT 1

Indexed keywords

IMMEDIATE EARLY PROTEIN; INFECTED CELL PROTEIN 27; INTERFERON; INTERFERON REGULATORY FACTOR; JANUS KINASE; STAT1 PROTEIN; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL NUCLEUS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME INHIBITION; GENE ACTIVITY; GENE EXPRESSION; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; VIRUS INFECTIVITY;

ANIMALS; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; DOWN-REGULATION; HERPESVIRUS 1, HUMAN; IMMEDIATE-EARLY PROTEINS; INTERFERON TYPE I; INTERFERON-ALPHA; MUTATION; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TRANSFECTION; VERO CELLS;

HUMAN HERPESVIRUS 1; SIMPLEXVIRUS;

EID: 42649143255     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.01.001     Document Type: Article

References (43)

1. Ackermann M., Braun D.K., Pereira L., and Roizman B. Characterization of herpes simplex virus 1 alpha proteins 0, 4, and 27 with monoclonal antibodies. J. Virol. 52 (1984) 108-118
2. Cai W.Z., and Schaffer P.A. Herpes simplex virus type 1 ICP0 plays a critical role in the de novo synthesis of infectious virus following transfection of viral DNA. J. Virol. 63 (1989) 4579-4589
3. Chee V.A., and Roizman B. Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites. J. Virol. 78 (2004) 4185-4196
4. Chou J., Chen J.-J., Gross M., and Roizman B. Association of a novel M190,000 phosphoprotein with PKR kinase in cells exhibiting enhanced phosphorylation of eIF-2alpha and premature shutoff of protein synthesis after infection with g-134.5-mutants of herpes simplex virus 1. Proc. Nat. Acad. Sci. U. S. A. 92 (1995) 10516-10520
5. DeLuca N.A., and Schaffer P.A. Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4. J. Virol. 62 (1988) 732-743
6. Der S.D., Zhou A., Williams B.R.G., and Silverman R.H. Idenification of genes differentially regulated by interferon alpha, beta or gamma using oligonucleotide arrays. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 15623-15628
7. Didcock L., Young D.F., Goodbourn S., and Randall R.E. Sendai virus and simian virus 5 block activation of interferon-responsive genes: importance for virus pathogenesis. J. Virol. 73 (1999) 3125-3133
8. Fraser K.A., and Rice S.A. Herpes simplex virus type 1 infection leads to loss of serine-2 phosphorylation on the carboxyl-terminal domain of RNA polymerase II. J. Virol. 79 (2005) 11323-11334
9. Garcia-Sastre A., and Biron C.A. Type 1 interferons and the virus-host relationship: a lesson in detente. Science 312 (2006) 879-882
10. Halford W.P., Weisend C., Grace J., Soboleski M., Carr D.J., Balliet J.W., Imai Y., Margolis T.P., and Gebhardt B.M. ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency. Virol. J. 3 1 (2006) 44
11. Hardwicke M.A., and Sandri-Goldin R.M. The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection. J. Virol. 68 (1994) 4797-4810
12. He B., Chou J., Brandimarti R., Mohr I., Gluzman Y., and Roizman B. Suppression of the phenotype of gamma(1)34.5-herpes simplex virus 1: failure of activated RNA-dependent protein kinase to shut off protein synthesis is associated with a deletion in the domain of the alpha47 gene. J. Virol. 71 8 (1997) 6049-6054
13. Honess R.W., and Roizman B. Regulation of herpesvirus macro-molecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins. J. Virol. 14 (1974) 8-19
14. Honess R.W., and Roizman B. Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides. Proc. Natl. Acad. Sci. U. S. A. 72 (1975) 1276-1280
15. Kim D.-B., and DeLuca N. Phosphorylation of transcription factor Sp1 during herpes simplex virus type 1 infection. J. Virol. 76 (2002) 6473-6479
16. Knipe D.M., and Spang A.E. Definition of a series of stages in the association of two herpesviral proteins with the cell nucleus. J. Virol. 43 (1982) 314-324
17. Knipe D.M., Senechek D., Rice S.A., and Smith J.L. Stages in the nuclear association of the herpes simplex virus transcriptional activator protein ICP4. J. Virol. 61 (1987) 276-284
18. Koffa M.D., Kean J., Zachos G., Rice S.A., and Clements J.B. CK2 protein kinase is stimulated and redistributed by functional herpes simplex virus ICP27 protein. J. Virol. 77 (2003) 4315-4325
19. Komatsu T., Takeuchi K., Yokoo J., Tanaka Y., and Gotoh B. Sendai virus blocks alpha interferon signaling to signal transducers and activators of transcription. J. Virol. 74 (2000) 2477-2480
20. Leonard G.T., and Sen G.C. Restoration of interferon responses of adenovirus E1A-expressing HT1080 cell lines by overexpression of p48 protein. J. Virol. 71 (1997) 5095-5101
21. McCarthy A.M., McMahan L., and Schaffer P.A. Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient. J. Virol. 63 (1989) 18-27
22. Melchjorsen J., Siren J., Julkunen I., Paludan S.R., and Matikainen S. Induction of cytokine expression by herpes simplex virus in human monocyte-derived macrophages and dendritic cells is dependent on virus replication and is counteracted by ICP27 targeting NF-kappaB and IRF-3. J. Gen. Virol. 87 Pt 5 (2006) 1099-1108
23. Melroe G., DeLuca N., and Knipe D.M. Herpes simplex virus 1 has multiple mechanisms for blocking virus-induced interferon production. J. Virol. 78 (2004) 8411-8420
24. Melroe G.T., Silva L., Schaffer P.A., and Knipe D.M. Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: potential role in blocking IFN-beta induction. Virology 360 (2007) 305-321
25. Mossman K. Analysis of anti-interferon properties of the herpes simplex virus type I ICP0 protein. Methods Mol. Med. 116 (2005) 195-205
26. Olesky M., McNamee E.E., Zhou C., Taylor T.J., and Knipe D.M. Evidence for a direct interaction between HSV-1 ICP27 and ICP8 proteins. Virology 331 (2005) 94-105
27. Park M.S., Shaw M.L., Munoz-Jordan J., Cros J.F., Nakaya T., Bouvier N., Palese P., Garcia-Sastre A., and Basler C.F. Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins. J. Virol. 77 (2003) 1501-1511
28. Platanias L.C., and Fish E.N. Signaling pathways activated by interferons. Exp. Hematol. 27 (1999) 1583-1592
29. Ragimbeau J., Dondi E., Alcover A., Eid P., Uze G., and Pellegrini S. The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression. EMBO J. 22 (2003) 537-547
30. Read G.S., and Frenkel N. Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides. J. Virol. 46 (1983) 498-512
31. Rice S.A., and Knipe D.M. Gene-specific transactivation by herpes simplex virus type 1 alpha protein ICP27. J. Virol. 62 (1988) 3814-3823
32. Rice S.A., and Knipe D.M. Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27. J. Virol. 64 (1990) 1704-1715
33. Sacks W.R., Greene C.C., Aschman D.P., and Schaffer P.A. Herpes simplex virus type 1 ICP27 is an essential regulatory protein. J. Virol. 55 (1985) 796-805
34. Samaniego L.A., Wu N., and DeLuca N.A. The herpes simplex virus immediate-early protein ICP0 affects transcription from the viral genome and infected-cell survival in the absence of ICP4 and ICP27. J. Virol. 71 (1997) 4614-4625
35. Samuel C.E. Antiviral actions of interferons. Clin. Microbiol. Rev. 14 (2001) 778-809
36. Sciabica K.S., Dai Q.J., and Sandri-Goldin R.M. ICP27 interacts with SRPK1 to mediate HSV splicing inhibition by altering SR protein phosphorylation. EMBO J. 22 (2003) 1608-1619
37. Sobol P.T., and Mossman K.L. ICP0 prevents RNase L-independent rRNA cleavage in herpes simplex virus type 1-infected cells. J. Virol. 80 (2006) 218-225
38. Wilcox K.W., Kohn A., Sklyanskaya E., and Roizman B. Herpes simplex virus phosphoproteins. I. Phosphate cycles on and off some viral polypeptides and can alter their affinity for DNA. J. Virol. 33 (1980) 167-182
39. Xia K., DeLuca N.A., and Knipe D.M. Analysis of phosphorylation sites of the herpes simplex virus 1 infected cell protein 4 (ICP4). J. Virol. 70 (1996) 1061-1071
40. Yokota S., Yokosawa N., Kubota T., Suzutani T., Yoshida I., Miura S., Jimbow K., and Fujii N. Herpes simplex virus type 1 suppresses the interferon signaling pathway by inhibiting phosphorylation of STATs and Janus kinases during an early infection stage. Virology 286 (2001) 119-124
41. Yokota S., Yokosawa N., Okabayashi T., Suzutani T., Miura S., Jimbow K., and Fujii N. Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway. J. Virol. 78 (2004) 6282-6286
42. Yokota S., Yokosawa N., Okabayashi T., Suzutani T., and Fujii N. Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 confers efficient viral replication. Virol 338 (2005) 173-181
43. Young D.F., Didcock L., Goodbourn S., and Randall R.E. Paramyxoviridae use distinct virus-specific mechanisms to circumvent the interferon response. Virology 269 (2000) 383-390