Zinc binding activity of human metapneumovirus M2-1 protein is indispensable for viral replication and pathogenesis in vivo

Journal of Virology

Volumn 89, Issue 12, 2015, Pages 6391-6405

  Cai, Hui ^a   Zhang, Yu ^a   Ma, Yuanmei ^a   Sun, Jing ^a   Liang, Xueya ^a   Li, Jianrong ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; HISTIDINE; M2 1 PROTEIN; NEUTRALIZING ANTIBODY; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; CARRIER PROTEIN; MUTANT PROTEIN; PROTEIN BINDING; ZINC; ZINC-BINDING PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; BINDING KINETICS; BINDING SITE; CIRCULAR DICHROISM; CONTROLLED STUDY; COTTON RAT; FEMALE; HISTOPATHOLOGY; HUMAN METAPNEUMOVIRUS; HUMAN METAPNEUMOVIRUS INFECTION; HUMORAL IMMUNITY; IMMUNOGENICITY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR CLONING; MOLECULAR DYNAMICS; NONHUMAN; OLIGOMERIZATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS STRAIN; ZINC BINDING ACTIVITY; ZINC BINDING MOTIF; ANIMAL; CELL LINE; DISEASE MODEL; GENETICS; HUMAN; METABOLISM; METAPNEUMOVIRUS; PARAMYXOVIRUS INFECTION; PATHOLOGY; PHYSIOLOGY; PROTEIN MULTIMERIZATION; SIGMODONTINAE; VIROLOGY;

HUMAN METAPNEUMOVIRUS; PARAMYXOVIRIDAE; PARAMYXOVIRINAE; PNEUMOVIRINAE; SIGMODON;

ANIMALS; CARRIER PROTEINS; CELL LINE; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; METAPNEUMOVIRUS; MUTANT PROTEINS; PARAMYXOVIRIDAE INFECTIONS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; SIGMODONTINAE; VIRAL PROTEINS; VIRUS REPLICATION; ZINC;

EID: 84929591128     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03488-14     Document Type: Article

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