Expression of human and macaque type I IFN transgenes interferes with HSV-1 replication at the transcriptional and translational levels: IFN-β is more potent than IFN-α2

Virology

Volumn 290, Issue 2, 2001, Pages 237-248

  Härle, Peter ^a   Lauret, Evelyne ^b   Pitha, Paula M ^c   De Maeyer, Edward ^d   Carr, Daniel J J ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b IGR   (France)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Les Genièvres   (France)

Author keywords

Gene therapy; HSV 1; IFN stimulatory genes; IFN 2; IFN

Indexed keywords

ALPHA2 INTERFERON; BETA INTERFERON; INTERFERON; STAT1 PROTEIN; VIRUS PROTEIN;

ARTICLE; CELL CYCLE; CELL TRANSFORMATION; CONTROLLED STUDY; DNA VECTOR; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; GENE THERAPY; GENETIC TRANSCRIPTION; HERPES SIMPLEX VIRUS 1; HUMAN; LYSIS; MACACA; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RNA TRANSLATION; TRANSGENE; VIRUS GENE; VIRUS REPLICATION; VIRUS TITRATION;

HERPES; HUMAN HERPESVIRUS 1; SIMPLEXVIRUS;

EID: 0035950915     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2001.1178     Document Type: Article

References (46)

1. Interferon inhibits herpes simplex virus-specific translation: A reinvestigation
2. Unexpected correlation in the sensitivity of 19 herpes simplex virus strains to types I and II interferons
3. Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/ caspase-8 death signaling pathway
4. The DNA sequence of the human cytomegalovirus genome
5. The novel receptors that mediate the entry of herpes simplex viruses and animal alphaherpesviruses into cells
6. The 2-5A system in viral infection and apoptosis
7. Effect of cloned human interferons on protein synthesis and morphogenesis of herpes simplex virus
8. Effect of recombinant hybrid human interferon on replication and morphogenesis of HSV-1 in monkey cells
9. Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture
10. A plasmid construct encoding murine interferon beta antagonizes the replication of herpes simplex virus type I in vitro and in vivo
11. The complete DNA sequence of varicella-zoster virus
12. Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein
13. Type I interferons
14. The genome sequence of herpes simplex virus type 2
15. Are all type I human interferons equivalent?
16. Synthesis of herpes simplex virus proteins in interferon-treated human cells
17. Activation of the Jak-Stat pathway in cells that exhibit selective sensitivity to the antiviral effects of IFN-beta compared with IFN-alpha
18. Perturbation of cell cycle progression and cellular gene expression as a function of herpes simplex virus ICPO
19. Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial
20. Virus interference. I. The interferon
21. The structure of human interferon-beta: Implications for activity
22. Effect of deficiency of the double-stranded RNA-dependent protein kinase. PKR, on antiviral resistance in the presence or absence of ribonuclease L: HSV-1 replication is particularly sensitive to deficiency of the major IFN-mediated enzymes
23. Reduction of both pro- and anti-inflammatory cytokines after 6 months of interferon beta-1a treatment of multiple sclerosis
24. Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene
25. Herpes simplex virus type 1 immediate-early protein Vmw110 inhibits progression of cells through mitosis and from G(1) into S phase of the cell cycle
26. Effect of interferon treatment on vesicular stomatitis virus (VSV): Release of unusual particles with low infectivity
27. Defective transport of herpes simplex virus glycoprotein in interferon-treated cells: Role of intracellular pH
28. Type I interferons keep activated T cells alive
29. Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas
30. Formation of non-infective herpesvirus particles in cultured cells treated with human interferon
31. Ectopic expression of DNA encoding IFN-alpha 1 in the cornea protects mice from herpes simplex virus type 1-induced encephalitis
32. Inhibition of transcription of herpes simplex virus immediate early genes in interferon-treated human cells
33. Interferon and retinoic acid in the treatment of human cancer: Mechanisms of action
34. Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis
35. Herpes simplex virus type 1 U(L)34 gene product is required for viral envelopment
36. Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities
37. How cells respond to interferons
38. Biological activities of recombinant murine interferons alpha 1 and alpha 4: Large difference in antiproliferative effect
39. Type I interferons are essential mediators of apoptotic death in virally infected cells
40. The effects of interferon-alpha on the production and action of other cytokines
41. The DNA sequence of equine herpesvirus-1
42. Interferons and other cytokines
43. Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways
44. Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22
45. Antiviral activities of individual murine IFN-alpha subtypes in vivo: Intramuscular injection of IFN expression constructs reduces cytomegalovirus replication
46. Interferons in the management of viral hepatitis