AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects

Autophagy

Volumn 12, Issue 2, 2016, Pages 273-286

  Papp, Diána ^a   Kovács, Tibor ^a,b   Billes, Viktor ^a,b   Varga, Máté ^b   Tarnóci, Anna ^a,b   Hackler, László ^c   Puskás, László G ^c,d   Liliom, Hanna ^b   Tárnok, Krisztián ^b   Schlett, Katalin ^b   Borsy, Adrienn ^e   Pádár, Zsolt ^a   Kovács, Attila L ^b   Hegedűs, Krisztina ^b   Juhász, Gábor ^b   Komlós, Marcell ^a   Erdős, Attila ^a   Gulyás, Balázs ^f,g,h   Vellai, Tibor ^a,b  

^a Velgene Biotechnology Research Ltd   (Hungary)

^b EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^c AVIDIN LTD   (Hungary)

^d INSTITUTE OF BIOCHEMISTRY   (Hungary)

^e INSTITUTE OF ENZYMOLOGY   (Hungary)

^f KAROLINSKA INSTITUTE   (Sweden)

^g NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^h IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Age dependent diseases; Aging; AUTEN 67; Autophagy induction; Drug candidate; EDTP; HeLa cells; LC3B II; Model organism; MTMR14 jumpy; Neuroprotection; SQSTM1 p62

Indexed keywords

AMYLOID PRECURSOR PROTEIN; AUTOPHAGY ENHANCER 67; MTMR14 ENZYME; NEUROPROTECTIVE AGENT; PHOSPHATASE; UNCLASSIFIED DRUG; MTMR14 PROTEIN, HUMAN; N-(3-(BENZIMIDAZOL-1-YL)-1,4-DIOXONAPHTHALEN-2-YL)-4-NITROBENZENESULFONAMIDE; NAPHTHOQUINONE; SULFONAMIDE;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; CELL DEATH; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; FAT BODY; HUMAN; HUMAN CELL; LIFE EXTENSION; LONGEVITY; MEMBRANE STRUCTURE; MOUSE; NERVE CELL; NESTING; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; ANIMAL; CHEMISTRY; DROSOPHILA MELANOGASTER; DRUG EFFECTS; FAT PAD; FEMALE; HELA CELL LINE; MALE; METABOLISM; ZEBRA FISH;

AGING; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; AUTOPHAGY; DROSOPHILA MELANOGASTER; FAT BODY; FEMALE; HELA CELLS; HUMANS; LONGEVITY; MALE; MICE; NAPHTHOQUINONES; NESTING BEHAVIOR; NEUROPROTECTION; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PHOSPHORIC MONOESTER HYDROLASES; SULFONAMIDES; ZEBRAFISH;

EID: 84964489801     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2015.1082023     Document Type: Article

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