Telmisartan-induced PPARγ activity attenuates lipid accumulation in VSMCs via induction of autophagy

Molecular Biology Reports

Volumn 42, Issue 1, 2015, Pages 179-186

  Li, Bing Hu ^a   Liao, Shao Qiong ^a   Yin, Yan Wei ^a   Long, Chun Yan ^a   Guo, Lu ^a   Cao, Xiao Jie ^a   Liu, Yun ^a   Zhou, Yi ^a   Gao, Chang Yue ^a   Zhang, Li Li ^a   Li, Jing Cheng ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Atherosclerosis; Autophagy; Foam cell; Peroxisome proliferator activated receptor ; Telmisartan; Vascular smooth muscle cell

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; BECLIN 1; CHOLESTEROL; DYE; GREEN FLUORESCENT PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LIGHT CHAIN 3; MAMMALIAN TARGET OF RAPAMYCIN; OIL RED O; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN; RAPAMYCIN; SMALL INTERFERING RNA; TELMISARTAN; UNCLASSIFIED DRUG; ADENYLATE KINASE; BENZIMIDAZOLE DERIVATIVE; BENZOIC ACID DERIVATIVE; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL TISSUE; AORTA; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL ISOLATION; CHOLESTEROL BLOOD LEVEL; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DOSE RESPONSE; ENZYME INHIBITION; GENETIC TRANSFECTION; INCUBATION TIME; LIPID STORAGE; MALE; MONOTHERAPY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SMOOTH MUSCLE FIBER; TREATMENT FAILURE; VASCULAR SMOOTH MUSCLE CELL; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CYTOLOGY; DRUG EFFECTS; FOAM CELL; LIPID METABOLISM; METABOLISM; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE;

ADENYLATE KINASE; ANIMALS; AUTOPHAGY; BENZIMIDAZOLES; BENZOATES; DOSE-RESPONSE RELATIONSHIP, DRUG; FOAM CELLS; LIPID METABOLISM; MALE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PPAR GAMMA; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84922072705     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-014-3757-6     Document Type: Article

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