Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways

FASEB Journal

Volumn 27, Issue 8, 2013, Pages 3384-3394

  Al Qusairi, Lama ^a,b,c,d,f   Prokic, Ivana ^a,b,c,d   Amoasii, Leonela ^a,b,c,d   Kretz, Christine ^a,b,c,d   Messaddeq, Nadia ^a,b,c,d   Mandel, Jean Louis ^a,b,c,d,e   Laporte, Jocelyn ^a,b,c,d  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b INSERM   (France)

^c CNRS   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

^e The Collège de France   (France)

^f UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Atrogene; Atrophy; Centronuclear myopathy; Myotubular myopathy

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MUSCLE PROTEIN; MYOTUBULARIN; PROTEASOME; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHRL1; UBIQUITIN; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, MOUSE; INSULIN-LIKE GROWTH FACTOR-1, MOUSE; MAP1LC3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; MTOR PROTEIN, MOUSE; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CENTRONUCLEAR MYOPATHY; CONTROLLED STUDY; MOUSE; MUSCLE MASS; MYOPATHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; X LINKED MYOTUBULAR MYOPATHY; 129 MOUSE; ANIMAL; DEFICIENCY; ELECTRON MICROSCOPY; GENE EXPRESSION; GENETICS; KNOCKOUT MOUSE; MALE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; ULTRASTRUCTURE; WESTERN BLOTTING;

ANIMALS; AUTOPHAGY; BLOTTING, WESTERN; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MICE, 129 STRAIN; MICE, KNOCKOUT; MICROSCOPY, ELECTRON; MICROTUBULE-ASSOCIATED PROTEINS; MUSCLE, SKELETAL; MYOPATHIES, STRUCTURAL, CONGENITAL; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN TYROSINE PHOSPHATASES, NON-RECEPTOR; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, IGF TYPE 1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; UBIQUITIN;

EID: 84881137026     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-220947     Document Type: Article

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