TLR9 ligation in pancreatic stellate cells promotes tumorigenesis

Journal of Experimental Medicine

Volumn 212, Issue 12, 2015, Pages 2077-2094

  Zambirinis, Constantinos P ^a   Levie, Elliot ^a   Nguy, Susanna ^a   Avanzi, Antonina ^a   Barilla, Rocky ^a   Xu, Yijie ^a   Seifert, Lena ^a   Daley, Donnele ^a   Greco, Stephanie H ^a   Deutsch, Michael ^a   Jonnadula, Saikiran ^a   Torres Hernandez, Alejandro ^a   Tippens, Daniel ^a   Pushalkar, Smruti ^b   Eisenthal, Andrew ^a   Saxena, Deepak ^b   Ahn, Jiyoung ^a   Hajdu, Cristina ^a   Engle, Dannielle D ^c   Tuveson, David ^c   Miller, George ^a   more..

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY COLLEGE OF DENTISTRY   (United States)

^c Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; COLLAGENASE 3; CYCLIN B1; CYCLIN D1; EOTAXIN; GELATINASE B; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 5; MYC PROTEIN; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P27; PROTEIN P53; STAT3 PROTEIN; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 4; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR; CHEMOKINE; CPG ODN 1826; LIGAND; OLIGODEOXYRIBONUCLEOTIDE;

ANIMAL CELL; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CONDITIONED MEDIUM; CONTROLLED STUDY; CYTOKINE RESPONSE; EPITHELIUM CELL; FIBROBLAST; FLOW CYTOMETRY; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOSUPPRESSIVE TREATMENT; MOUSE; MYELOID DERIVED SUPPRESSOR CELL; NONHUMAN; PANCREAS ADENOCARCINOMA; PANCREATIC STELLATE CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; SUPPRESSOR CELL; TUMOR MICROENVIRONMENT; UPREGULATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL TRANSFORMATION; CONFOCAL MICROSCOPY; DRUG EFFECTS; GENETICS; IMMUNOBLOTTING; KNOCKOUT MOUSE; METABOLISM; PANCREAS TUMOR; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CHEMOKINE CCL11; CHEMOKINES; EPITHELIAL CELLS; IMMUNOBLOTTING; LIGANDS; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; OLIGODEOXYRIBONUCLEOTIDES; PANCREATIC NEOPLASMS; PANCREATIC STELLATE CELLS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 9; TUMOR MICROENVIRONMENT;

EID: 84964391958     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20142162     Document Type: Article

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