Frequency, antimicrobial resistance and genetic diversity of Klebsiella pneumoniae in food samples

PLoS ONE

Volumn 11, Issue 4, 2016, Pages

  Guo, Yumei ^a   Zhou, Haijian ^b,c   Qin, Liyun ^a   Pang, Zhizhao ^a   Qin, Tian ^b,c   Ren, Hongyu ^b   Pan, Zhuo ^a   Zhou, Jikun ^a  

^a Shijiazhuang Center for Disease Control and Prevention   (China)

^b National Institute for Communicable Diseases Prevention and Control   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMIKACIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; ASPARTIC ACID; AZTREONAM; CEFAZOLIN; CEFEPIME; CEFOTAXIME; CEFTAZIDIME; CHLORAMPHENICOL; CIPROFLOXACIN; COLISTIN; COTRIMOXAZOLE; GENTAMICIN; IMIPENEM; ISOLEUCINE; LEVOFLOXACIN; MEROPENEM; MOXIFLOXACIN; PHENYLALANINE; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; SERINE; SULTAMICILLIN; TETRACYCLINE; ANTINEOPLASTIC AGENT;

AAC(6') LB CR GENE; AACA4 GENE; AACC2 GENE; AADA1 GENE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM CONTAMINATION; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; BLACTX M 1 GENE; BLACTX M 10 GENE; BLASHV GENE; CHICKEN; CONTROLLED STUDY; COOKED FOOD; DHFR GENE; ESCHERICHIA COLI; FOOD CONTAMINATION; FOOD FREEZING; GENE MUTATION; GENETIC VARIABILITY; GYRA GENE; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; PARC GENE; PHENOTYPE; POLYMERASE CHAIN REACTION; QNRA GENE; QNRB GENE; QNRS GENE; RAW FOOD; SEA FOOD; ANIMAL; DRUG EFFECTS; FOOD CONTROL; GENETIC VARIATION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; KLEBSIELLA INFECTIONS; MICROBIOLOGY; MUTATION; POULTRY;

ANIMALS; ANTINEOPLASTIC AGENTS; CHICKENS; DRUG RESISTANCE, BACTERIAL; FOOD MICROBIOLOGY; GENES, BACTERIAL; GENETIC VARIATION; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MUTATION; POULTRY; SEAFOOD;

EID: 84964330918     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0153561     Document Type: Article

References (57)

1. Podschun R, Ullmann U. Klebsiellaspp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin. Microbiol Rev. 1998;11:589-603. PMID: 9767057
2. Struve C, Krogfelt KA. Pathogenic potential of environmental Klebsiella pneumoniae isolates. Environ Microbiol. 2004;6:584-590. doi:10.1111/j.1462-2920.2004.00590.x PMID: 15142246
3. Marchaim D, Navon-Venezia S, Schwaber MJ, Carmeli Y. Isolation of imipenem-resistantEnterobacter species: emergence of KPC-2 carbapenemase, molecular characterization, epidemiology, and outcomes. Antimicrob Agents Chemother. 2008;52:1413-1418. doi:10.1128/AAC.01103-07 PMID: 18227191
4. Pfeifer Y, Cullik A, Witte W. Resistance to cephalosporins and carbapenems in Gram-negative bacterial pathogens. Int J Med Microbiol. 2010;300:371-379. doi:10.1016/j.ijmm.2010.04.005 PMID: 20537585
5. Yang J, Luo Y, Cui S, Wang W, Han L. Diverse phenotypic and genotypic characterization among clinical Klebsiella pneumoniae and Escherichia coli isolates carrying plasmid-mediated quinolone resistance determinants. Microb Drug Resist. 2011;17:363-367. doi:10.1089/mdr.2011.0034 PMID: 21563956
6. Kuchenmüller T, Abela-Ridder B, Corrigan T, Tritscher A. World Health Organization initiative to estimate the global burden of foodborne diseases. Rev SciTech. 2013;32:459-467. PMID: 24547649
7. McLinden T, Sargeant JM, Thomas MK, Papadopoulos A, Fazil A. Component costs of foodborne illness: a scoping review. BMC Public Health. 2014;14:509. doi:10.1186/1471-2458-14-509 PMID: 24885154
8. Falomir MP, Rico H, Gozalbo D. Enterobacter and Klebsiella species isolated from fresh vegetables marketed in Valencia (Spain) and their clinically relevant resistances to chemotherapeutic agents. Foodborne Pathog Dis. 2013;10:1002-1007. doi:10.1089/fpd.2013.1552 PMID: 23980710
9. Nawaz M, Khan SA, Tran Q, Sung K, Khan AA, Adamu I, et al. Isolation and characterization of multidrug-resistant klebsiellaspp. Isolated from shrimp imported from Thailand. IntJ Food Microbiol. 2012;155:179-184. doi:10.1016/j.ijfoodmicro.2012.02.002 PMID: 22405354
10. Wu H, Liu BG, Liu JH, Pan YS, Yuan L, Hu GZ. Phenotypic and molecular characterization of CTX-M-14 extended-spectrum p-lactamase and plasmid-mediated act-like AmpC p-lactamase produced by Klebsiella pneumoniae isolates from chickens in Henan Province, China. Genet Mol Res. 2012;11:3357-3364. doi:10.4238/2012. September.24.1 PMID: 23079829
11. Calbo E, Freixas N, Xercavins M, Riera M, Nicolás C, Monistrol O, et al. Foodborne nosocomial outbreak of SHV1 and CTX-M-15-producingKlebsiellapneumoniae: epidemiology and control. Clin Infect Dis. 2011;52:743-749. doi:10.1093/cid/ciq238 PMID: 21367727
12. Clinical and Laboratory Standards Institute (CLSI). Performance standards for antimicrobial susceptibility testing; Twenty-first informational supplement. CLSI document M100-S24:2014. Wayne, PA: CLSI; 2014.
13. Magiorakos AP, Srinivasan A, Carey RB, Carmeli Y, Falagas ME, Giske CG, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect. 2012;18:268-281. doi:10.1111/j. 1469-0691.2011.03570.x PMID: 21793988
14. Schlesinger J, Navon-Venezia S, Chmelnitsky I, Hammer-Münz O, Leavitt A, Gold HS, et al. Extendedspectrum beta-lactamases among Enterobacter isolates obtained in Tel Aviv, Israel. Antimicrob Agents Chemother. 2005;49:1150-1156. doi:10.1128/AAC.49.3.1150-1156.2005 PMID: 15728917
15. Krishnamurthy V, Vijaykumar GS, Sudeepa KM, Prashanth HV, Prakash R, Nagaraj ER. Phenotypic and genotypic methods for detection of extended spectrum p lactamase producing Escherichia coli and Klebsiella pneumoniae isolated from ventilator associated pneumonia. J Clin Diagn Res. 2013;7:1975-1978. doi:10.7860/JCDR/2013/6544.3376 PMID: 24179913
16. Kawakami S, Ono Y, Yamamoto M, Matumura M, Okamoto R, Inoue M, et al. [Extended-spectrum beta-lactamase (ESBL) produced by Escherichia coli and Klebsiella pneumoniae isolated from Teikyo University Hospital-the second report]. Kansenshogaku Zasshi. 2000;74:24-29. doi:10.11150/kansenshogakuzasshi1970.74.24 PMID: 10695291
17. Gao W, Sun Z, Yin J, Wang Q, Cheng J, Ye Y, et al. Studies on resistance and genotypes of CTX-M extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae in Anhui province. Chin J Antibiot. 2009;34:48-51.
18. Messai Y, Iabadene H, Benhassine T, Alouache S, Tazir M, Gautier V, et al. Prevalence and characterization of extended-spectrum beta-lactamases in Klebsiella pneumoniae in Algiers hospitals (Algeria). Pathol Biol. 2008;56:319-325. doi:10.1016/j.patbio.2008.05.008 PMID: 18585867
19. Oliver A, Pérez-Díaz JC, Coque TM, Baquero F, Cantón R. Nucleotide sequence and characterization of a novel Cefotaxime-hydrolyzing beta-lactamase (CTX-M-10) isolated in Spain. Antimicrob Agents Chemother. 2001;45:616-620. doi:10.1128/AAC.45.2.616-620.2001 PMID: 11158766
20. Espedido BA, Steen JA, Ziochos H, Grimmond SM, Cooper MA, Gosbell IB, et al. Whole genome sequence analysis of the first Australian OXA-48-producing outbreak-associated Klebsiella pneumoniae isolates: the resistome and in vivo evolution. PLOS ONE. 2013;8:e59920. doi:10.1371/journal. pone.0059920 PMID: 23555831
21. Zhang Y, Zhang K. Study on b-lactams resistance and genotype of blactamases in plasmid-mediated AmpC b-lactamases and ESBLs producing bacteria. Chin J Microbiol Immunol. 2004;24:577-582.
22. Pérez-Pérez FJ, Hanson ND. Detection of plasmid-mediated AmpC beta-lactamase genes in clinical isolates by using multiplex PCR. J Clin Microbiol. 2002;40:2153-2162. PMID: 12037080
23. Coudron PE, Hanson ND, Climo MW. Occurrence of extended-spectrum and AmpC beta-lactamases in bloodstream isolates of Klebsiella pneumoniae: isolates harbor plasmid-mediated FOX-5 and ACT-1 AmpC betalactamases. J Clin Microbiol. 2003;41:772-777. doi:10.1128/JCM.41.2.772-777.2003 PMID: 12574281
24. Leavitt A, Chmelnitsky I, Ofek I, Carmeli Y, Navon-Venezia S. PlasmidpKpQILencoding KPC-3and TEM-1 confers carbapenem resistance in an extremely drug-resistant epidemic Klebsiella pneumoniae strain. J Antimicrob Chemother. 2010;65:243-248. doi:10.1093/jac/dkp417 PMID: 19939824
25. Robicsek A, Strahilevitz J, Jacoby GA, Macielag M, Abbanat D, Park CH, et al. Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase. Nat Med. 2006;12:83-88. doi:10.1038/nm1347 PMID: 16369542
26. Kim HB, Park CH, Kim CJ, Kim EC, Jacoby GA, Hooper DC. Prevalence of plasmid-mediated quinolone resistance determinants over a 9-year period. Antimicrob Agents Chemother. 2009;53:639-645. doi:10.1128/AAC.01051-08 PMID: 19064896
27. Cavaco LM, Hasman H, Xia S, Aarestrup FM. qnrD, a novel gene conferring transferable quinolone resistance in Salmonella enterica serovar Kentucky and Bovismorbificans strains of human origin. Antimicrob Agents Chemother. 2009;53:603-608. doi:10.1128/AAC.00997-08 PMID: 19029321
28. Robicsek A, Sahm DF, Strahilevitz J, Jacoby GA, Hooper DC. Broader distribution of plasmid-mediated quinolone resistance in the United States. Antimicrob Agents Chemother. 2005;49:3001-3003. doi:10.1128/AAC.49.7.3001-3003.2005 PMID: 15980384
29. Park CH, Robicsek A, Jacoby GA, Sahm D, Hooper DC. Prevalence in the United States of aac (6')-Ibcr encoding a ciprofloxacin-modifying enzyme. Antimicrob Agents Chemother. 2006;50:3953-3955. doi:10.1128/AAC.00915-06 PMID: 16954321
30. Weigel LM, Steward CD, Tenover FC. gyrA mutations associated with fluoroquinolone resistance in eight species of Enterobacteriaceae. Antimicrob Agents Chemother. 1998;42:2661-2667. PMID: 9756773
31. Zimhony O, Chmelnitsky I, Bardenstein R, Goland S, Hammer Muntz O, Navon Venezia S, et al. Endocarditis caused by extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae: emergence of resistance to ciprofloxacin and piperacillin-tazobactam during treatment despite initial susceptibility. Antimicrob Agents Chemother. 2006;50:3179-3182. doi:10.1128/AAC.00218-06 PMID: 16940124
32. Hujer KM, Hujer AM, Hulten EA, Bajaksouzian S, Adams JM, Donskey CJ, et al. Analysis of antibiotic resistance genes in multidrug-resistant Acinetobactersp. Isolates from military and civilian patients treated at the Walter Reed Army Medical Center. Antimicrob Agents Chemother. 2006;50:4114-4123. doi:10.1128/AAC.00778-06 PMID: 17000742
33. Ma L, Lin CJ, Chen JH, Fung CP, Chang FY, Lai YK, et al. Widespread dissemination of aminoglycoside resistance genes armA and rmtB in Klebsiella pneumoniae isolates in Taiwan producing CTX-M-type extended-spectrum beta-lactamases. Antimicrob Agents Chemother. 2009;53:104-111. doi:10. 1128/AAC.00852-08 PMID: 18936188
34. Bissonnette L, Roy PH. Characterization of In0 of Pseudomonas aeruginosa plasmid pVS1, an ancestor of integrons of multiresistance plasmids and transposons of Gram-negative bacteria. J Bacteriol. 1992;174:1248-1257. PMID: 1310501
35. Han H, Zhou H, Li H, Gao Y, Lu Z, Hu K, et al. Optimization of pulse-field gel electrophoresis for subtyping of Klebsiella pneumoniae. Int J Environ Res Public Health. 2013;10:2720-2731. doi:10.3390/ijerph10072720 PMID: 23880721
36. Dice LR. Measures of the amount of ecologic association between species. Ecology. 1945;26:297-302. doi:10.2307/1932409
37. Diancourt L, Passet V, Verhoef J, Grimont PA, Brisse S. Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates. J Clin Microbiol. 2005;43:4178-4182. doi:10.1128/JCM.43.8.4178-4182.2005 PMID: 16081970
38. Wu H, Wang Y, Wu Y, Qiao J, Li H, Zheng S, et al. Emergence of (5-lactamases and extended-Spectrum p-lactamases (ESBLs) producing salmonella in retail raw chicken in China. Foodborne Pathog Dis. 2015;12:228-234. doi:10.1089/fpd.2014.1859 PMID: 25658910
39. Anderl JN, Franklin MJ, Stewart PS. Role of antibiotic penetration limitation in Klebsiella pneumoniae biofilm resistance to ampicillin and ciprofloxacin. Antimicrob Agents Chemother. 2000;44:1818-1824. doi:10.1128/AAC.44.7.1818-1824.2000 PMID: 10858336
40. Hernández-Allés S, BenedíVJ, Martínez-Martínez L, Pascual A, Aguilar A, Tomás JM, et al. Development of resistance during antimicrobial therapy caused by insertion sequence interruption of porin genes. Antimicrob Agents Chemother. 1999;43:937-939. PMID: 10103203
41. Schneiders T, Amyes SG, Levy SB. Role of AcrR and ramA in fluoroquinolone resistance in clinical Klebsiella pneumoniae isolates from Singapore. Antimicrob Agents Chemother. 2003;47:2831-2837. doi:10.1128/AAC.47.9.2831-2837.2003 PMID: 12936981
42. Dhillon RH, Clark J. ESBLs: A clear and present danger? CritCar. Res Pract. 2012;2012:625170.
43. Meier S, Weber R, Zbinden R, Ruef C, Hasse B. Extendedspectrum fi-lactamase-producing Gram-negative pathogens in community-acquired urinary tract infections: an increasing challenge for antimicrobial therapy. Infection. 2011;39:333-340. doi:10.1007/s15010-011-0132-6 PMID: 21706226
44. Tumbarello M, Sanguinetti M, Montuori E, Trecarichi EM, Posteraro B, Fiori B, et al. Predictors of mortality in patients with bloodstream infections caused by extended-spectrum-beta-lactamase producing Enterobacteriaceae: importance of inadequate initial antimicrobial treatment. Antimicrob Agents Chemother. 2007;51:1987-1994. doi:10.1128/AAC.01509-06 PMID: 17387156
45. An S, Chen J, Wang Z, Wang X, Yan X, Li J, et al. Predominant characteristics of CTX-M-producing Klebsiella pneumoniae isolates from patients with lower respiratory tract infection in multiple medical centers in China. FEMS Microbiol Lett. 2012;332:137-145. doi:10.1111/j.1574-6968.2012.02586.x PMID: 22537112
46. Turner MS, Andersson P, Bell JM, Turnidge JD, Harris T, Giffard PM. Plasmid-borne blaSHV genes in Klebsiella pneumoniae are associated with strong promoters. J Antimicrob Chemother. 2009;64:960-964. doi:10.1093/jac/dkp338 PMID: 19749204
47. Younes A, Hamouda A, Dave J, Amyes SG. Prevalence of transferable blaCTX-M-15 from hospitaland community-acquired Klebsiella pneumoniae isolates in Scotland. J Antimicrob Chemother. 2011;66:313-318. doi:10.1093/jac/dkq453 PMID: 21131694
48. Belmar Campos C, Fenner I, Wiese N, Lensing C, Christner M, Rohde H, et al. Prevalence and genotypes of extended spectrum beta-lactamases in Enterobacteriaceae isolated from human stool and chicken meat in Hamburg, Germany. Int J Med Microbiol. 2014;304:678-684. doi:10.1016/j.ijmm. 2014.04.012 PMID: 24856867
49. Casella T, Rodríguez MM, Takahashi JT, Ghiglione B, Dropa M, Assunçao E, et al. Detection of blaCTX-M-type genes in complex class 1 integrons carried by Enterobacteriaceae isolated from retail chicken meat in Brazil. Int J Food Microbiol. 2015;197:88-91. doi:10.1016/j.ijfoodmicro.2014.12.001 PMID: 25576985
50. Chon JW, Jung HI, Kuk M, Kim YJ, Seo KH, Kim SK. High occurrence of extended-Spectrum (5-lactamase-producingsalmonellain broiler carcasses from poultry slaughterhouses in South Korea. Foodborne Pathog Dis. 2015;12:190-196. doi:10.1089/fpd.2014.1847 PMID: 25692653
51. Li B, Yi Y, Wang Q, Woo PC, Tan L, Jing H, et al. Analysis of drug resistance determinants in Klebsiella pneumoniae isolates from a tertiary-care hospital in Beijing, China. PLOSONE. 2012;7:e42280. doi:10.1371/journal.pone.0042280 PMID: 22860106
52. Woodford N, Eastaway AT, Ford M, Leanord A, Keane C, Quayle RM, et al. Comparison of BD Phoenix, Vitek 2 and MicroScan automated systems for detection and inference of mechanisms responsible for carbapenem resistance in Enterobacteriaceae. J Clin Microbiol. 2010;48:2999-3002. doi:10.1128/JCM.00341-10 PMID: 20534805
53. Deguchi T, Fukuoka A, Yasuda M, Nakano M, Ozeki S, Kanematsu E, et al. Alterations in the GyrAsubunit of DNA gyrase and the ParC subunit of topoisomerase IV in quinolone-resistant clinical isolates of Klebsiella pneumoniae. Antimicrob Agents Chemother. 1997;41:699-701. PMID: 9056017
54. Aathithan S, French GL. Hypermutability in clinical isolates of Klebsiella pneumoniae is uncommon and is unrelated to ciprofloxacin resistance. Int J Antimicrob Agents. 2010;36:239-242. doi:10.1016/j. ijantimicag.2010.04.010 PMID: 20541915
55. Chen FJ, Lauderdale TL, Ho M, Lo HJ. The roles of mutations ingyrA, parC and OmpK35 in fluoroquinolone resistance in Klebsiella pneumoniae. Microb Drug Resist. 2003;9:265-271. doi:10.1089/107662903322286472 PMID: 12959405
56. Hopkins KL, Davies RH, Threlfall EJ. Mechanisms of quinolone resistance in Escherichia coli and salmonella: recent developments. Int J Antimicrob Agents. 2005;25:358-373. doi:10.1016/j.ijantimicag. 2005.02.006 PMID: 15848289
57. Velhner M, Kozoderovic G, Grego E, Galic N, Stojanov I, Jelesic Z, et al. Clonal spread of Salmonella enterica serovar Infantis in Serbia: acqu ISItion of mutations in the topoisomerase genes gyrA and parC leads to increased resistance to fluoroquinolones. Zoonoses Public Health. 2014;61:364-370. doi:10. 1111/zph.12081 PMID: 24119387