Whole Genome Sequence Analysis of the First Australian OXA-48-Producing Outbreak-Associated Klebsiella pneumoniae Isolates: The Resistome and In Vivo Evolution

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Espedido, Björn A ^a,b   Steen, Jason A ^c   Ziochos, Helen ^d   Grimmond, Sean M ^c   Cooper, Matthew A ^c   Gosbell, Iain B ^a,b,d   van Hal, Sebastiaan J ^a,e   Jensen, Slade O ^a,b  

^a UNIVERSITY OF WESTERN SYDNEY   (Australia)

^b INGHAM INSTITUTE FOR APPLIED MEDICAL RESEARCH   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d New South Wales Government   (Australia)

^e ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE; BETA LACTAMASE CTX M; BETA LACTAMASE OXA 48; CARBAPENEM; RIFAMPICIN; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; AUSTRALIA; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM CARRIER; BACTERIUM ISOLATE; BLA OXA 48 GENE; CLONAL VARIATION; CONTROLLED STUDY; DRUG TOLERANCE; ENZYME SYNTHESIS; EPIDEMIC; GENE IDENTIFICATION; GENETIC ASSOCIATION; HUMAN; IN VIVO STUDY; INTENSIVE CARE UNIT; KLEBSIELLA PNEUMONIAE; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; RESISTOME; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION REGULATION;

ANTI-BACTERIAL AGENTS; AUSTRALIA; BETA-LACTAMASES; CARBAPENEMS; CROSS INFECTION; DISEASE OUTBREAKS; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; GENOME, BACTERIAL; HUMANS; INTENSIVE CARE UNITS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; PLASMIDS; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA; TRANSCRIPTION, GENETIC; VIRULENCE;

ENTEROBACTERIACEAE; KLEBSIELLA PNEUMONIAE;

EID: 84875503927     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059920     Document Type: Article

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