A labdane diterpene exerts ex vivo and in vivo cardioprotection against post-ischemic injury: Involvement of AKT-dependent mechanisms

Biochemical Pharmacology

Volumn 93, Issue 4, 2015, Pages 428-439

  Cuadrado Berrocal, Irene ^a   Gómez Gaviro, María V ^b,c   Benito, Yolanda ^b   Barrio, Alicia ^b   Bermejo, Javier ^b   Fernández Santos, María Eugenia ^b   Sánchez, Pedro L ^b   Desco, Manuel ^b,c   Fernández Avilés, Francisco ^b   Fernández Velasco, María ^d,e   Boscá, Lisardo ^d,e   De Las Heras, Beatriz ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^c UNIVERSIDAD CARLOS III DE MADRID   (Spain)

^d INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^e HOSPITAL UNIVERSITARIO LA PAZ IDIPAZ   (Spain)

Author keywords

Apoptosis; Cardioprotection; Heart; Ischemia reperfusion injury; Labdane diterpenes

Indexed keywords

ADENYLATE KINASE; CARDIOVASCULAR AGENT; DEHYDROISOHISPANOLONE; DITERPENE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; POLYCYSTIN 1; POLYCYSTIN 2; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; EX VIVO STUDY; HEART INFARCTION; HEART MUSCLE CELL; HEART PROTECTION; IN VIVO STUDY; LEFT CORONARY ARTERY; MALE; NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION; REPERFUSION INJURY;

EID: 84964258736     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.12.011     Document Type: Article

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