Effect of pressure overload on cardioprotection via PI3K-Akt: Comparison of postconditioning, insulin, and pressure unloading

American Journal of Hypertension

Volumn 23, Issue 6, 2010, Pages 668-674

  Mozaffari, Mahmood S ^a   Liu, Jun Yao ^a   Schaffer, Stephen W ^b  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

GSK 3 ; Hypertension; Infarct size; PDK1; Perfusion pressure; PI3K Akt; Postconditioning; Pressure unloading; PTEN; Rat

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HYPERVOLEMIA; MALE; NONHUMAN; POSTCONDITIONING; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; GLYCOGEN SYNTHASE KINASE 3; HEART; INSULIN; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PRESSURE; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 77952525188     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1038/ajh.2010.43     Document Type: Article

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