Supression of inflammatory responses by labdane-type diterpenoids

Toxicology and Applied Pharmacology

Volumn 228, Issue 2, 2008, Pages 179-189

  Girón, Natalia ^a   Través, Paqui G ^b   Rodríguez, Benjamín ^c   López Fontal, Raquel ^d   Boscá, Lisardo ^b   Hortelano, Sonsoles ^d   de las Heras, Beatriz ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^c INSTITUTO DE QUÍMICA ORGÁNICA GENERAL   (Spain)

^d CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

Author keywords

Inflammation; NF B; Nitric oxide; Terpenoids

Indexed keywords

CYCLOOXYGENASE 2; DITERPENOID; I KAPPA B ALPHA; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LABDANE DITERPENOID; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MYELOPEROXIDASE; NITRIC OXIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PROSTAGLANDIN E3; PROTEIN SUBUNIT; SYNAPTOTAGMIN I; TERPENOID DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CELL RECEPTOR; DITERPENE; DNA BINDING PROTEIN; LABDANE; LIVER X RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; NONSTEROID ANTIINFLAMMATORY AGENT; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; EAR EDEMA; EDEMA; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IC 50; IN VIVO STUDY; MACROPHAGE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; APOPTOSIS; BIOSYNTHESIS; CELL LINE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; FLOW CYTOMETRY; GENETIC TRANSFECTION; GENETICS; INFLAMMATION; METABOLISM; PATHOLOGY; PHOSPHORYLATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; CYCLOOXYGENASE 2; DITERPENES; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HUMANS; INFLAMMATION; MACROPHAGES; MAP KINASE KINASE KINASES; MICE; MOLECULAR STRUCTURE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION FACTOR RELA; TRANSFECTION;

EID: 41549124148     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.12.006     Document Type: Article

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