An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis

American Journal of Pathology

Volumn 186, Issue 5, 2016, Pages 1206-1220

  Nastase, Madalina Viviana ^a,c   Zeng Brouwers, Jinyang ^a   Frey, Helena ^a   Hsieh, Louise Tzung Harn ^a   Poluzzi, Chiara ^a   Beckmann, Janet ^a   Schroeder, Nina ^a   Pfeilschifter, Josef ^a   Lopez Mosqueda, Jaime ^a   Mersmann, Jan ^b   Ikeda, Fumiyo ^d   Iozzo, Renato V ^e   Dikic, Ivan ^a   Schaefer, Liliana ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^c NATIONAL INSTITUTE FOR CHEMICAL PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (Romania)

^d INSTITUTE OF MOLECULAR BIOTECHNOLOGY   (Austria)

^e THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 11; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN P10; PROTEIN P20; REGULATOR PROTEIN; SHANK ASSOCIATED REGULATOR OF G PROTEIN SIGNALING HOMOLOGY DOMAIN INTERACTING PROTEIN; UNCLASSIFIED DRUG; CASP11 PROTEIN, MOUSE; CASPASE; CASPASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; NERVE PROTEIN; SHARPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; DIMERIZATION; ENZYME ACTIVATION; LIPOPOLYSACCHARIDE-INDUCED ENDOTOXEMIA; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SEPSIS; SPLEEN CELL; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; DEFICIENCY; DERMATITIS; DOWN REGULATION; ENDOTOXEMIA; ENZYMOLOGY; GENE SILENCING; GENETIC TRANSFECTION; KNOCKOUT MOUSE; LUNG; METABOLISM; PHENOTYPE; PHYSIOLOGY; SALMONELLA;

ANIMALS; CASPASE 1; CASPASE INHIBITORS; CASPASES; CELLS, CULTURED; DERMATITIS; DOWN-REGULATION; ENDOTOXEMIA; GENE KNOCKDOWN TECHNIQUES; INTERLEUKIN-18; INTERLEUKIN-1BETA; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; LUNG; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NF-KAPPA B; PHENOTYPE; SALMONELLA; SEPSIS; TRANSFECTION;

EID: 84964048156     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2015.12.026     Document Type: Article

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