-
1
-
-
0035110856
-
Sharpin, a novel postsynaptic density protein that directly interacts with the shank family of proteins
-
Lim S, Sala C, Yoon J, et al. Sharpin, a novel postsynaptic density protein that directly interacts with the shank family of proteins. Mol Cell Neurosci. 2001; 17: 385-97.
-
(2001)
Mol Cell Neurosci
, vol.17
, pp. 385-397
-
-
Lim, S.1
Sala, C.2
Yoon, J.3
-
2
-
-
80455143827
-
SHARPIN is an endogenous inhibitor of [beta]1-integrin activation
-
Rantala JK, Pouwels J, Pellinen T, et al. SHARPIN is an endogenous inhibitor of [beta]1-integrin activation. Nat Cell Biol. 2011; 13: 1315-24.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1315-1324
-
-
Rantala, J.K.1
Pouwels, J.2
Pellinen, T.3
-
3
-
-
17444424974
-
The structure of alpha-helical coiled coils
-
Lupas AN, Gruber M. The structure of alpha-helical coiled coils. Adv Protein Chem. 2005; 70: 37-78.
-
(2005)
Adv Protein Chem
, vol.70
, pp. 37-78
-
-
Lupas, A.N.1
Gruber, M.2
-
4
-
-
65249166493
-
Functional roles of ubiquitin-like domain (ULD) and ubiquitin-binding domain (UBD) containing proteins
-
Grabbe C, Dikic I. Functional roles of ubiquitin-like domain (ULD) and ubiquitin-binding domain (UBD) containing proteins. Chem Rev. 2009; 109: 1481-94.
-
(2009)
Chem Rev
, vol.109
, pp. 1481-1494
-
-
Grabbe, C.1
Dikic, I.2
-
5
-
-
4344712350
-
TAB 2 and TAB 3 activate the NF-kappaB pathway through binding to polyubiquitin chains
-
Kanayama A, Seth RB, Sun L, et al. TAB 2 and TAB 3 activate the NF-kappaB pathway through binding to polyubiquitin chains. Mol Cell. 2004; 15: 535-48.
-
(2004)
Mol Cell
, vol.15
, pp. 535-548
-
-
Kanayama, A.1
Seth, R.B.2
Sun, L.3
-
6
-
-
79953239980
-
SHARPIN forms a linear ubiquitin ligase complex regulating NF-kappaB activity and apoptosis
-
Ikeda F, Deribe YL, Skanland SS, et al. SHARPIN forms a linear ubiquitin ligase complex regulating NF-kappaB activity and apoptosis. Nature. 2011; 471: 637-41.
-
(2011)
Nature
, vol.471
, pp. 637-641
-
-
Ikeda, F.1
Deribe, Y.L.2
Skanland, S.S.3
-
7
-
-
80052906832
-
Linear polyubiquitin chains: a new modifier involved in NFkappaB activation and chronic inflammation, including dermatitis
-
Iwai K. Linear polyubiquitin chains: a new modifier involved in NFkappaB activation and chronic inflammation, including dermatitis. Cell Cycle. 2011; 10: 3095-104.
-
(2011)
Cell Cycle
, vol.10
, pp. 3095-3104
-
-
Iwai, K.1
-
8
-
-
79953237668
-
SHARPIN is a component of the NF-kappaB-activating linear ubiquitin chain assembly complex
-
Tokunaga F, Nakagawa T, Nakahara M, et al. SHARPIN is a component of the NF-kappaB-activating linear ubiquitin chain assembly complex. Nature. 2011; 471: 633-6.
-
(2011)
Nature
, vol.471
, pp. 633-636
-
-
Tokunaga, F.1
Nakagawa, T.2
Nakahara, M.3
-
9
-
-
0027773019
-
A spontaneous mutation characterized by chronic proliferative dermatitis in C57BL mice
-
HogenEsch H, Gijbels MJ, Offerman E, et al. A spontaneous mutation characterized by chronic proliferative dermatitis in C57BL mice. Am J Pathol. 1993; 143: 972-82.
-
(1993)
Am J Pathol
, vol.143
, pp. 972-982
-
-
HogenEsch, H.1
Gijbels, M.J.2
Offerman, E.3
-
10
-
-
34547422758
-
Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis
-
Seymour RE, Hasham MG, Cox GA, et al. Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis. Genes Immun. 2007; 8: 416-21.
-
(2007)
Genes Immun
, vol.8
, pp. 416-421
-
-
Seymour, R.E.1
Hasham, M.G.2
Cox, G.A.3
-
11
-
-
0028932296
-
Ultrastructure of epidermis of mice with chronic proliferative dermatitis
-
Gijbels MJ, HogenEsch H, Blauw B, et al. Ultrastructure of epidermis of mice with chronic proliferative dermatitis. Ultrastruct Pathol. 1995; 19: 107-11.
-
(1995)
Ultrastruct Pathol
, vol.19
, pp. 107-111
-
-
Gijbels, M.J.1
HogenEsch, H.2
Blauw, B.3
-
12
-
-
0030091271
-
Pathogenesis of skin lesions in mice with chronic proliferative dermatitis (cpdm/cpdm)
-
Gijbels MJ, Zurcher C, Kraal G, et al. Pathogenesis of skin lesions in mice with chronic proliferative dermatitis (cpdm/cpdm). Am J Pathol. 1996; 148: 941-50.
-
(1996)
Am J Pathol
, vol.148
, pp. 941-950
-
-
Gijbels, M.J.1
Zurcher, C.2
Kraal, G.3
-
13
-
-
0033120961
-
Absence of Peyer's patches and abnormal lymphoid architecture in chronic proliferative dermatitis (cpdm/cpdm) mice
-
HogenEsch H, Janke S, Boggess D, et al. Absence of Peyer's patches and abnormal lymphoid architecture in chronic proliferative dermatitis (cpdm/cpdm) mice. J Immunol. 1999; 162: 3890-6.
-
(1999)
J Immunol
, vol.162
, pp. 3890-3896
-
-
HogenEsch, H.1
Janke, S.2
Boggess, D.3
-
14
-
-
79953240109
-
Linear ubiquitination prevents inflammation and regulates immune signalling
-
Gerlach B, Cordier SM, Schmukle AC, et al. Linear ubiquitination prevents inflammation and regulates immune signalling. Nature. 2011; 471: 591-6.
-
(2011)
Nature
, vol.471
, pp. 591-596
-
-
Gerlach, B.1
Cordier, S.M.2
Schmukle, A.C.3
-
15
-
-
0035081842
-
Increased expression of type 2 cytokines in chronic proliferative dermatitis (cpdm) mutant mice and resolution of inflammation following treatment with IL-12
-
HogenEsch H, Torregrosa SE, Boggess D, et al. Increased expression of type 2 cytokines in chronic proliferative dermatitis (cpdm) mutant mice and resolution of inflammation following treatment with IL-12. Eur J Immunol. 2001; 31: 734-42.
-
(2001)
Eur J Immunol
, vol.31
, pp. 734-742
-
-
HogenEsch, H.1
Torregrosa, S.E.2
Boggess, D.3
-
16
-
-
84863133303
-
SHARPIN is essential for cytokine production, NF-κB signaling, and induction of Th1 differentiation by dendritic cells
-
Wang Z, Sokolovska A, Seymour R, et al. SHARPIN is essential for cytokine production, NF-κB signaling, and induction of Th1 differentiation by dendritic cells. PLoS One. 2012; 7: e31809.
-
(2012)
PLoS One
, vol.7
-
-
Wang, Z.1
Sokolovska, A.2
Seymour, R.3
-
17
-
-
24644465726
-
Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma
-
Elias JA, Homer RJ, Hamid Q, et al. Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma. J Allergy Clin Immunol. 2005; 116: 497-500.
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 497-500
-
-
Elias, J.A.1
Homer, R.J.2
Hamid, Q.3
-
18
-
-
33748889496
-
Expression of chitinase-like proteins in the skin of chronic proliferative dermatitis (cpdm/cpdm) mice
-
HogenEsch H, Dunham A, Seymour R, et al. Expression of chitinase-like proteins in the skin of chronic proliferative dermatitis (cpdm/cpdm) mice. Exp Dermatol. 2006; 15: 808-14.
-
(2006)
Exp Dermatol
, vol.15
, pp. 808-814
-
-
HogenEsch, H.1
Dunham, A.2
Seymour, R.3
-
19
-
-
61849152860
-
Eosinophils in asthma - closing the loop or opening the door?
-
Wenzel SE. Eosinophils in asthma - closing the loop or opening the door? N Engl J Med. 2009; 360: 1026-8.
-
(2009)
N Engl J Med
, vol.360
, pp. 1026-1028
-
-
Wenzel, S.E.1
-
20
-
-
67049144615
-
Eosinophilic and neutrophilic inflammation in asthma: insights from clinical studies
-
Fahy JV. Eosinophilic and neutrophilic inflammation in asthma: insights from clinical studies. Proc Am Thorac Soc. 2009; 6: 256-9.
-
(2009)
Proc Am Thorac Soc
, vol.6
, pp. 256-259
-
-
Fahy, J.V.1
-
21
-
-
67651124902
-
The role of leukocytes, keratinocytes, and allergen-specific IgE in the development of atopic dermatitis
-
Werfel T. The role of leukocytes, keratinocytes, and allergen-specific IgE in the development of atopic dermatitis. J Invest Dermatol. 2009; 129: 1878-91.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 1878-1891
-
-
Werfel, T.1
-
22
-
-
58149355307
-
Atopic dermatitis: a disease caused by innate immune defects?
-
De Benedetto A, Agnihothri R, McGirt LY, et al. Atopic dermatitis: a disease caused by innate immune defects? J Invest Dermatol. 2009; 129: 14-30.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 14-30
-
-
De Benedetto, A.1
Agnihothri, R.2
McGirt, L.Y.3
-
25
-
-
77149121750
-
Anti-IL5 decreases the number of eosinophils but not the severity of dermatitis in Sharpin-deficient mice
-
Renninger ML, Seymour RE, Whiteley LO, et al. Anti-IL5 decreases the number of eosinophils but not the severity of dermatitis in Sharpin-deficient mice. Exp Dermatol. 2010; 19: 252-8.
-
(2010)
Exp Dermatol
, vol.19
, pp. 252-258
-
-
Renninger, M.L.1
Seymour, R.E.2
Whiteley, L.O.3
-
26
-
-
80053101302
-
Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies
-
Grabrucker AM, Schmeisser MJ, Schoen M, et al. Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies. Trends Cell Biol. 2011; 21: 594-603.
-
(2011)
Trends Cell Biol
, vol.21
, pp. 594-603
-
-
Grabrucker, A.M.1
Schmeisser, M.J.2
Schoen, M.3
-
27
-
-
78650289998
-
Inhibition of NF-kappaB signaling retards eosinophilic dermatitis in SHARPIN-deficient mice
-
Liang Y, Seymour RE, Sundberg JP. Inhibition of NF-kappaB signaling retards eosinophilic dermatitis in SHARPIN-deficient mice. J Invest Dermatol. 2011; 131: 141-9.
-
(2011)
J Invest Dermatol
, vol.131
, pp. 141-149
-
-
Liang, Y.1
Seymour, R.E.2
Sundberg, J.P.3
-
28
-
-
79960993122
-
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
-
Zak DE, Schmitz F, Gold ES, et al. Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses. Proc Natl Acad Sci USA. 2011; 108: 11536-41.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 11536-11541
-
-
Zak, D.E.1
Schmitz, F.2
Gold, E.S.3
-
29
-
-
80052014052
-
Inflammation meets cancer, with NF-kappaB as the matchmaker
-
Ben-Neriah Y, Karin M. Inflammation meets cancer, with NF-kappaB as the matchmaker. Nat Immunol. 2011; 12: 715-23.
-
(2011)
Nat Immunol
, vol.12
, pp. 715-723
-
-
Ben-Neriah, Y.1
Karin, M.2
-
31
-
-
33750435582
-
NF-kappaB and the immune response
-
Hayden MS, West AP, Ghosh S. NF-kappaB and the immune response. Oncogene. 2006; 25: 6758-80.
-
(2006)
Oncogene
, vol.25
, pp. 6758-6780
-
-
Hayden, M.S.1
West, A.P.2
Ghosh, S.3
-
32
-
-
38849199203
-
Shared principles in NF-kappaB signaling
-
Hayden MS, Ghosh S. Shared principles in NF-kappaB signaling. Cell. 2008; 132: 344-62.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
33
-
-
0141567432
-
Regulation of secondary lymphoid organ development by the nuclear factor-kappaB signal transduction pathway
-
Weih F, Caamano J. Regulation of secondary lymphoid organ development by the nuclear factor-kappaB signal transduction pathway. Immunol Rev. 2003; 195: 91-105.
-
(2003)
Immunol Rev
, vol.195
, pp. 91-105
-
-
Weih, F.1
Caamano, J.2
-
34
-
-
33750457370
-
Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway
-
Perkins ND. Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway. Oncogene. 2006; 25: 6717-30.
-
(2006)
Oncogene
, vol.25
, pp. 6717-6730
-
-
Perkins, N.D.1
-
35
-
-
27144529182
-
Ubiquitylation and cell signaling
-
Haglund K, Dikic I. Ubiquitylation and cell signaling. EMBO J. 2005; 24: 3353-9.
-
(2005)
EMBO J
, vol.24
, pp. 3353-3359
-
-
Haglund, K.1
Dikic, I.2
-
36
-
-
63649116570
-
Ubiquitylation in innate and adaptive immunity
-
Bhoj VG, Chen ZJ. Ubiquitylation in innate and adaptive immunity. Nature. 2009; 458: 430-7.
-
(2009)
Nature
, vol.458
, pp. 430-437
-
-
Bhoj, V.G.1
Chen, Z.J.2
-
37
-
-
59649086030
-
Nonproteolytic functions of ubiquitin in cell signaling
-
Chen ZJ, Sun LJ. Nonproteolytic functions of ubiquitin in cell signaling. Mol Cell. 2009; 33: 275-86.
-
(2009)
Mol Cell
, vol.33
, pp. 275-286
-
-
Chen, Z.J.1
Sun, L.J.2
-
38
-
-
78650090605
-
Ubiquitin makes its mark on immune regulation
-
Malynn BA, Ma A. Ubiquitin makes its mark on immune regulation. Immunity. 2010; 33: 843-52.
-
(2010)
Immunity
, vol.33
, pp. 843-852
-
-
Malynn, B.A.1
Ma, A.2
-
39
-
-
0030004897
-
Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity
-
Chen ZJ, Parent L, Maniatis T. Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity. Cell. 1996; 84: 853-62.
-
(1996)
Cell
, vol.84
, pp. 853-862
-
-
Chen, Z.J.1
Parent, L.2
Maniatis, T.3
-
40
-
-
0033068154
-
The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro
-
Winston JT, Strack P, Beer-Romero P, et al. The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro. Genes Dev. 1999; 13: 270-83.
-
(1999)
Genes Dev
, vol.13
, pp. 270-283
-
-
Winston, J.T.1
Strack, P.2
Beer-Romero, P.3
-
41
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang C, Deng L, Hong M, et al. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature. 2001; 412: 346-51.
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
Deng, L.2
Hong, M.3
-
42
-
-
1342304089
-
Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling
-
Varadan R, Assfalg M, Haririnia A, et al. Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling. J Biol Chem. 2004; 279: 7055-63.
-
(2004)
J Biol Chem
, vol.279
, pp. 7055-7063
-
-
Varadan, R.1
Assfalg, M.2
Haririnia, A.3
-
43
-
-
77949332322
-
The RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB
-
Zhang L, Blackwell K, Shi Z, et al. The RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB. J Mol Biol. 2010; 396: 528-39.
-
(2010)
J Mol Biol
, vol.396
, pp. 528-539
-
-
Zhang, L.1
Blackwell, K.2
Shi, Z.3
-
44
-
-
72149117664
-
TRAF2 must bind to cellular inhibitors of apoptosis for umor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis
-
Vince JE, Pantaki D, Feltham R, et al. TRAF2 must bind to cellular inhibitors of apoptosis for umor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis. J Biol Chem. 2009; 284: 35906-15.
-
(2009)
J Biol Chem
, vol.284
, pp. 35906-35915
-
-
Vince, J.E.1
Pantaki, D.2
Feltham, R.3
-
45
-
-
50149121101
-
Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation
-
Mahoney DJ, Cheung HH, Mrad RL, et al. Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation. Proc Natl Acad Sci USA. 2008; 105: 11778-83.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 11778-11783
-
-
Mahoney, D.J.1
Cheung, H.H.2
Mrad, R.L.3
-
46
-
-
54049155149
-
c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation
-
Varfolomeev E, Goncharov T, Fedorova AV, et al. c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation. J Biol Chem. 2008; 283: 24295-9.
-
(2008)
J Biol Chem
, vol.283
, pp. 24295-24299
-
-
Varfolomeev, E.1
Goncharov, T.2
Fedorova, A.V.3
-
47
-
-
71149119391
-
A tangled web of ubiquitin chains: breaking news in TNF-R1 signaling
-
Bianchi K, Meier P. A tangled web of ubiquitin chains: breaking news in TNF-R1 signaling. Mol Cell. 2009; 36: 736-42.
-
(2009)
Mol Cell
, vol.36
, pp. 736-742
-
-
Bianchi, K.1
Meier, P.2
-
48
-
-
77449153351
-
Regulation of death receptor signaling by the ubiquitin system
-
Wertz IE, Dixit VM. Regulation of death receptor signaling by the ubiquitin system. Cell Death Differ. 2010; 17: 14-24.
-
(2010)
Cell Death Differ
, vol.17
, pp. 14-24
-
-
Wertz, I.E.1
Dixit, V.M.2
-
49
-
-
33646034316
-
Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
-
Ea CK, Deng L, Xia ZP, et al. Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. Mol Cell. 2006; 22: 245-57.
-
(2006)
Mol Cell
, vol.22
, pp. 245-257
-
-
Ea, C.K.1
Deng, L.2
Xia, Z.P.3
-
50
-
-
76749132616
-
RIPK1 is not essential for TNFR1-induced activation of NF-kappaB
-
Wong WW, Gentle IE, Nachbur U, et al. RIPK1 is not essential for TNFR1-induced activation of NF-kappaB. Cell Death Differ. 2010; 17: 482-7.
-
(2010)
Cell Death Differ
, vol.17
, pp. 482-487
-
-
Wong, W.W.1
Gentle, I.E.2
Nachbur, U.3
-
51
-
-
33645703930
-
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]
-
Wu CJ, Conze DB, Li T, et al. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]. Nat Cell Biol. 2006; 8: 398-406.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 398-406
-
-
Wu, C.J.1
Conze, D.B.2
Li, T.3
-
52
-
-
3943054838
-
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
-
Wertz IE, O'Rourke KM, Zhou H, et al. De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. Nature. 2004; 430: 694-9.
-
(2004)
Nature
, vol.430
, pp. 694-699
-
-
Wertz, I.E.1
O'Rourke, K.M.2
Zhou, H.3
-
53
-
-
59649122882
-
Linear polyubiquitylation: the missing link in NF-kappaB signalling
-
Haas AL. Linear polyubiquitylation: the missing link in NF-kappaB signalling. Nat Cell Biol. 2009; 11: 116-8.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 116-118
-
-
Haas, A.L.1
-
54
-
-
67650064603
-
Linear polyubiquitination: a new regulator of NF-kappaB activation
-
Iwai K, Tokunaga F. Linear polyubiquitination: a new regulator of NF-kappaB activation. EMBO Rep. 2009; 10: 706-13.
-
(2009)
EMBO Rep
, vol.10
, pp. 706-713
-
-
Iwai, K.1
Tokunaga, F.2
-
55
-
-
33750219981
-
A ubiquitin ligase complex assembles linear polyubiquitin chains
-
Kirisako T, Kamei K, Murata S, et al. A ubiquitin ligase complex assembles linear polyubiquitin chains. EMBO J. 2006; 25: 4877-87.
-
(2006)
EMBO J
, vol.25
, pp. 4877-4887
-
-
Kirisako, T.1
Kamei, K.2
Murata, S.3
-
56
-
-
71149105333
-
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction
-
Haas TL, Emmerich CH, Gerlach B, et al. Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. Mol Cell. 2009; 36: 831-44.
-
(2009)
Mol Cell
, vol.36
, pp. 831-844
-
-
Haas, T.L.1
Emmerich, C.H.2
Gerlach, B.3
-
57
-
-
59649103156
-
Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation
-
Tokunaga F, Sakata S, Saeki Y, et al. Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation. Nat Cell Biol. 2009; 11: 123-32.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 123-132
-
-
Tokunaga, F.1
Sakata, S.2
Saeki, Y.3
-
58
-
-
0034746919
-
NF-kappaB: a key role in inflammatory diseases
-
Tak PP, Firestein GS. NF-kappaB: a key role in inflammatory diseases. J Clin Invest. 2001; 107: 7-11.
-
(2001)
J Clin Invest
, vol.107
, pp. 7-11
-
-
Tak, P.P.1
Firestein, G.S.2
-
60
-
-
70350513270
-
Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases
-
Pasparakis M. Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases. Nat Rev Immunol. 2009; 9: 778-88.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 778-788
-
-
Pasparakis, M.1
-
61
-
-
62549155321
-
Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
-
Rahighi S, Ikeda F, Kawasaki M, et al. Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation. Cell. 2009; 136: 1098-109.
-
(2009)
Cell
, vol.136
, pp. 1098-1109
-
-
Rahighi, S.1
Ikeda, F.2
Kawasaki, M.3
-
62
-
-
79960419007
-
NF-kappaB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-kappaB activation
-
Hadian K, Griesbach RA, Dornauer S, et al. NF-kappaB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-kappaB activation. J Biol Chem. 2011; 286: 26107-17.
-
(2011)
J Biol Chem
, vol.286
, pp. 26107-26117
-
-
Hadian, K.1
Griesbach, R.A.2
Dornauer, S.3
-
63
-
-
0033634663
-
Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti
-
Makris C, Godfrey VL, Krahn-Senftleben G, et al. Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti. Mol Cell. 2000; 5: 969-79.
-
(2000)
Mol Cell
, vol.5
, pp. 969-979
-
-
Makris, C.1
Godfrey, V.L.2
Krahn-Senftleben, G.3
-
64
-
-
0033638970
-
NEMO/IKK gamma-deficient mice model incontinentia pigmenti
-
Schmidt-Supprian M, Bloch W, Courtois G, et al. NEMO/IKK gamma-deficient mice model incontinentia pigmenti. Mol Cell. 2000; 5: 981-92.
-
(2000)
Mol Cell
, vol.5
, pp. 981-992
-
-
Schmidt-Supprian, M.1
Bloch, W.2
Courtois, G.3
-
65
-
-
0034713270
-
Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium
-
Smahi A, Courtois G, Vabres P, et al. Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium. Nature. 2000; 405: 466-72.
-
(2000)
Nature
, vol.405
, pp. 466-472
-
-
Smahi, A.1
Courtois, G.2
Vabres, P.3
-
66
-
-
0141989227
-
Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2
-
Yamanaka K, Ishikawa H, Megumi Y, et al. Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2. Nat Cell Biol. 2003; 5: 336-40.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 336-340
-
-
Yamanaka, K.1
Ishikawa, H.2
Megumi, Y.3
-
67
-
-
0029858387
-
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB
-
Wang CY, Mayo MW, Baldwin AS Jr. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science. 1996; 274: 784-7.
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin Jr., A.S.3
-
68
-
-
0029992609
-
Suppression of TNF-alpha-induced apoptosis by NF-kappaB
-
Van Antwerp DJ, Martin SJ, Kafri T, et al. Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science. 1996; 274: 787-9.
-
(1996)
Science
, vol.274
, pp. 787-789
-
-
Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
-
69
-
-
0033596127
-
Control of apoptosis by Rel/NF-kappaB transcription factors
-
Barkett M, Gilmore TD. Control of apoptosis by Rel/NF-kappaB transcription factors. Oncogene. 1999; 18: 6910-24.
-
(1999)
Oncogene
, vol.18
, pp. 6910-6924
-
-
Barkett, M.1
Gilmore, T.D.2
-
72
-
-
84863258188
-
Integrin signaling and function in immune cells
-
Zhang Y, Wang H. Integrin signaling and function in immune cells. Immunology. 2012; 135: 268-75.
-
(2012)
Immunology
, vol.135
, pp. 268-275
-
-
Zhang, Y.1
Wang, H.2
-
73
-
-
77954426684
-
Newly identified tumor-associated role of human Sharpin
-
Jung J, Kim JM, Park B, et al. Newly identified tumor-associated role of human Sharpin. Mol Cell Biochem. 2010; 340: 161-7.
-
(2010)
Mol Cell Biochem
, vol.340
, pp. 161-167
-
-
Jung, J.1
Kim, J.M.2
Park, B.3
-
74
-
-
77953213657
-
Shank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells
-
He L, Ingram A, Rybak AP, et al. Shank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells. J Clin Invest. 2010; 120: 2094-108.
-
(2010)
J Clin Invest
, vol.120
, pp. 2094-2108
-
-
He, L.1
Ingram, A.2
Rybak, A.P.3
|