Programmed cell death-1 (PD-1) and T-cell immunoglobulin mucin-3 (Tim-3) regulate CD4+ T cells to induce Type 2 helper T cell (Th2) bias at the maternal-fetal interface

Human Reproduction

Volumn 31, Issue 4, 2016, Pages 700-711

  Wang, SongCun ^a,b   Zhu, XiaoYong ^a,b   Xu, YuanYuan ^a,b   Zhang, Di ^a,b   Li, YanHong ^a,b   Tao, Yu ^a,b   Piao, HaiLan ^a,b   Li, DaJin ^a,b   Du, MeiRong ^a,b  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

CD4+T; miscarriage; PD 1; pregnancy; Th2 bias; Tim 3; trophoblast

Indexed keywords

ANTIBODY; GAMMA INTERFERON; GLYCOPROTEIN; KI 67 ANTIGEN; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 1 ANTIBODY; T LYMPHOCYTE IMMUNOGLOBULIN MUCIN 3; T LYMPHOCYTE IMMUNOGLOBULIN MUCIN 3 ANTIBODY; TRANSCRIPTION FACTOR GATA 3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; HAVCR2 PROTEIN, HUMAN; HEPATITIS A VIRUS CELLULAR RECEPTOR 2; NEUTRALIZING ANTIBODY; PDCD1 PROTEIN, HUMAN; PROGRAMMED DEATH 1 RECEPTOR; UTERUS SPASMOLYTIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; FETUS RESORPTION; FIRST TRIMESTER PREGNANCY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE FUNCTION; MALE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PREGNANCY OUTCOME; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SPONTANEOUS ABORTION; TH2 CELL; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; CELL CULTURE; CELL PROLIFERATION; COCULTURE; CROSS BREEDING; DECIDUA; DRUG EFFECTS; FETOMATERNAL TRANSFUSION; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; INDUCED ABORTION; METABOLISM; PATHOLOGY; PREGNANCY; PREVENTION AND CONTROL; RECURRENT ABORTION;

ABORTION, HABITUAL; ABORTION, INDUCED; ANIMALS; ANTIBODIES, NEUTRALIZING; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; COCULTURE TECHNIQUES; CROSSES, GENETIC; DECIDUA; FEMALE; FETAL RESORPTION; HEPATITIS A VIRUS CELLULAR RECEPTOR 2; HUMANS; IMMUNE TOLERANCE; MATERNAL-FETAL EXCHANGE; MICE; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PROGRAMMED CELL DEATH 1 RECEPTOR; TH2 CELLS; TOCOLYTIC AGENTS;

EID: 84963978886     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/dew019     Document Type: Article

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