Impaired selectin-dependent leukocyte recruitment induces T-cell exhaustion and prevents chronic allograft vasculopathy and rejection

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 33, 2014, Pages 12145-12150

  Sarraj, Bara ^a   Ye, Junsheng ^a,b   Akl, Ahmed Ibrahim ^a   Chen, Guodong ^a   Wang, Jiao Jing ^a   Zhang, Zheng ^a   Abadja, Farida ^a   Abecassis, Michael ^a   Miller, Stephen D ^a   Kansas, Geoffrey S ^a   Ansari, M Javeed ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Adhesion; Apoptosis; Traffic

Indexed keywords

CYCLOSPORIN; FUCOSYLAL TRANSFERASE VII; FUCOSYLTRANSFERASE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 7 RECEPTOR ALPHA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MUCIN; MYCOPHENOLIC ACID; PROGRAMMED DEATH 1 RECEPTOR; SELECTIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 4;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; APOPTOSIS; ARTICLE; AUTOIMMUNITY; CARDIAC ALLOGRAFT VASCULOPATHY; CD4+ T LYMPHOCYTE; CHRONIC GRAFT REJECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; EFFECTOR CELL; ENZYME ASSAY; GRAFT RECIPIENT; GRAFT SURVIVAL; HEART GRAFT; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; INFLAMMATION; KIDNEY GRAFT; LEUKOCYTE; LEUKOCYTE MIGRATION; LYMPHOCYTE FUNCTION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; REGULATORY T LYMPHOCYTE; REPERFUSION INJURY; SPLEEN; SURVIVAL TIME; T CELL EXHAUSTION;

ADHESION; APOPTOSIS; TRAFFIC;

ADOPTIVE TRANSFER; ALLOGRAFTS; BLOOD VESSELS; CD4-POSITIVE T-LYMPHOCYTES; CELL MOVEMENT; FLOW CYTOMETRY; FUCOSYLTRANSFERASES; GRAFT REJECTION; HUMANS; LEUKOCYTES; SELECTINS;

EID: 84906319228     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1303676111     Document Type: Article

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