Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury

Journal of Hepatology

Volumn 62, Issue 3, 2015, Pages 563-572

  Liu, Yuanxing ^a,b   Ji, Haofeng ^a   Zhang, Yu ^a,b   Shen, Xiuda ^a   Gao, Feng ^a   He, Xiangyi ^a,c   Li, Gabriella A ^a   Busuttil, Ronald W ^a   Kuchroo, Vijay K ^d   Kupiec Weglinski, Jerzy W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ZHEJIANG UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Galectin 9; Innate immunity; Ischemia reperfusion injury; Liver; Orthotopic liver transplantation; TIM 3

Indexed keywords

ALANINE AMINOTRANSFERASE; CASPASE 3; CASPASE 7; ECALECTIN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; MESSENGER RNA; REGULATOR PROTEIN; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR GATA 3; TUMOR NECROSIS FACTOR ALPHA; ADENOSINE; ALLOPURINOL; GALECTIN; GALECTIN 9, MOUSE; GLUTATHIONE; HAVCR2 PROTEIN, MOUSE; INSULIN; PRESERVATION SOLUTION; RAFFINOSE; UNIVERSITY OF WISCONSIN-LACTOBIONATE SOLUTION; VIRUS RECEPTOR;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL LEVEL; CELL PROTECTION; CONTROLLED STUDY; GRAFT RECIPIENT; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; LIVER CELL; LIVER CELL DAMAGE; LIVER PROTECTION; LIVER TRANSPLANTATION; MACROPHAGE FUNCTION; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; ORGAN DONOR; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH1 CELL; 129 MOUSE; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; DISEASE MODEL; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; MACROPHAGE; NEUTROPHIL; ORGAN PRESERVATION; PATHOLOGY; TRANSGENIC MOUSE;

ADENOSINE; ALLOPURINOL; ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; GALECTINS; GLUTATHIONE; HEPATOCYTES; IMMUNITY, INNATE; IN VITRO TECHNIQUES; INSULIN; LIVER TRANSPLANTATION; LYMPHOCYTE ACTIVATION; MACROPHAGES; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NEUTROPHILS; ORGAN PRESERVATION; ORGAN PRESERVATION SOLUTIONS; RAFFINOSE; RECEPTORS, VIRUS; REPERFUSION INJURY; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 84923048590     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.10.034     Document Type: Article

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