-
2
-
-
0025339511
-
A cell culture model for T lymphocyte clonal anergy
-
Schwartz RH. A cell culture model for T lymphocyte clonal anergy. Science 1990;248:1349-1356.
-
(1990)
Science
, vol.248
, pp. 1349-1356
-
-
Schwartz, R.H.1
-
3
-
-
0025947895
-
CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells
-
Jenkins MK, Taylor PS, Norton SD, Urdahl KB. CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells. J Immunol 1991;147:1461-1466.
-
(1991)
J Immunol
, vol.147
, pp. 1461-1466
-
-
Jenkins, M.K.1
Taylor, P.S.2
Norton, S.D.3
Urdahl, K.B.4
-
4
-
-
0032543306
-
The role of T cell costimulatory activation in transplant rejection
-
Sayegh MH, Turka LA. The role of T cell costimulatory activation in transplant rejection. N Engl J Med 1998;338:1813-1821.
-
(1998)
N Engl J Med
, vol.338
, pp. 1813-1821
-
-
Sayegh, M.H.1
Turka, L.A.2
-
7
-
-
0242322243
-
CD28 costimulation: A source of Vav-1 for TCR signaling with the help of SLP-76?
-
Michel F, Acuto O. CD28 costimulation: a source of Vav-1 for TCR signaling with the help of SLP-76? Sci STKE 2002;2002:PE35.
-
(2002)
Sci STKE
, vol.2002
-
-
Michel, F.1
Acuto, O.2
-
8
-
-
0037117823
-
CTLA-4 negative signaling via lipid rafts: A new perspective
-
Rudd CE, Martin M, Schneider H. CTLA-4 negative signaling via lipid rafts: a new perspective. Sci STKE 2002;2002:PE18.
-
(2002)
Sci STKE
, vol.2002
-
-
Rudd, C.E.1
Martin, M.2
Schneider, H.3
-
9
-
-
0037023014
-
Ordered just so: Lipid rafts and lymphocyte function
-
Sedwick CE, Altman A. Ordered just so: lipid rafts and lymphocyte function. Sci STKE 2002;2002:RE2.
-
(2002)
Sci STKE
, vol.2002
-
-
Sedwick, C.E.1
Altman, A.2
-
10
-
-
0025830902
-
CTLA-4 is a second receptor for the B cell activation antigen B7
-
Linsley PS, Brady W, Urnes M, Grosmaire LS, Damle NK, Ledbetter JA. CTLA-4 is a second receptor for the B cell activation antigen B7. J Exp Med 1991;174:561-569.
-
(1991)
J Exp Med
, vol.174
, pp. 561-569
-
-
Linsley, P.S.1
Brady, W.2
Urnes, M.3
Grosmaire, L.S.4
Damle, N.K.5
Ledbetter, J.A.6
-
12
-
-
0030659503
-
The CD40 pathway in allograft rejection, acceptance and tolerance
-
Larsen C, Pearson T. The CD40 pathway in allograft rejection, acceptance and tolerance. Curr Opin Immunol 1997;9:641-647.
-
(1997)
Curr Opin Immunol
, vol.9
, pp. 641-647
-
-
Larsen, C.1
Pearson, T.2
-
13
-
-
0031944607
-
CD40 and CD154 in cell-mediated immunity
-
Grewal IS, Flavell RA. CD40 and CD154 in cell-mediated immunity. Annu Rev Immunol 1998;16:111-135.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 111-135
-
-
Grewal, I.S.1
Flavell, R.A.2
-
14
-
-
0035292756
-
The expanding B7 superfamily: Increasing complexity in costimulatory signals regulating T cell function
-
Coyle AJ, Gutierrez-Ramos JC. The expanding B7 superfamily: increasing complexity in costimulatory signals regulating T cell function. Nat Immunol 2001;2:203-209.
-
(2001)
Nat Immunol
, vol.2
, pp. 203-209
-
-
Coyle, A.J.1
Gutierrez-Ramos, J.C.2
-
15
-
-
0036156661
-
The role of novel T cell costimulatory pathways in autoimmunity and transplantation
-
Yamada A, Salama AD, Sayegh MH. The role of novel T cell costimulatory pathways in autoimmunity and transplantation. J Am Soc Nephrol 2002;13:559-575.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 559-575
-
-
Yamada, A.1
Salama, A.D.2
Sayegh, M.H.3
-
16
-
-
0038246517
-
Alternative T-cell costimulatory pathways in transplant rejection and tolerance induction: Hierarchy or redundancy?
-
Salama AD, Sayegh MH. Alternative T-cell costimulatory pathways in transplant rejection and tolerance induction: hierarchy or redundancy? Am J Transplant 2003;3:509-511.
-
(2003)
Am J Transplant
, vol.3
, pp. 509-511
-
-
Salama, A.D.1
Sayegh, M.H.2
-
17
-
-
0026649765
-
Identification and distribution of the costimulatory receptor CD28 in the mouse
-
Gross JA, Callas E, Allison JP. Identification and distribution of the costimulatory receptor CD28 in the mouse. J Immunol 1992;149:380-388.
-
(1992)
J Immunol
, vol.149
, pp. 380-388
-
-
Gross, J.A.1
Callas, E.2
Allison, J.P.3
-
18
-
-
0033379266
-
Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection
-
Trambley J, et al. Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection. J Clin Invest 1999;104:1715-1722.
-
(1999)
J Clin Invest
, vol.104
, pp. 1715-1722
-
-
Trambley, J.1
-
19
-
-
0030057218
-
T cell activation determined by T cell receptor number and tunable thresholds
-
Viola A, Lanzavecchia A. T cell activation determined by T cell receptor number and tunable thresholds. Science 1996;273:104-106.
-
(1996)
Science
, vol.273
, pp. 104-106
-
-
Viola, A.1
Lanzavecchia, A.2
-
20
-
-
0024674480
-
Two distinct mechanisms of interleukin-2 gene expression in human T lymphocytes
-
June CH, Jackson KM, Ledbetter JA, Leiden JM, Lindsten T, Thompson CB. Two distinct mechanisms of interleukin-2 gene expression in human T lymphocytes. J Autoimmun 1989;2:55-65.
-
(1989)
J Autoimmun
, vol.2
, pp. 55-65
-
-
June, C.H.1
Jackson, K.M.2
Ledbetter, J.A.3
Leiden, J.M.4
Lindsten, T.5
Thompson, C.B.6
-
21
-
-
0033613826
-
T lymphocyte costimulation mediated by reorganization of membrane microdomains
-
Viola A, Schroeder S, Sakakibara Y, Lanzavecchia A. T lymphocyte costimulation mediated by reorganization of membrane microdomains. Science 1999;283:680-682.
-
(1999)
Science
, vol.283
, pp. 680-682
-
-
Viola, A.1
Schroeder, S.2
Sakakibara, Y.3
Lanzavecchia, A.4
-
22
-
-
0036221481
-
Signal transduction mediated by the T cell antigen receptor: The role of adapter proteins
-
Samelson LE. Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins. Annu Rev Immunol 2002;20:371-394.
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 371-394
-
-
Samelson, L.E.1
-
23
-
-
0032490620
-
Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28
-
Lin H, Rathmell JC, Gray GS, Thompson CB, Leiden JM, Alegre ML. Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28. J Exp Med 1998;188:199-204.
-
(1998)
J Exp Med
, vol.188
, pp. 199-204
-
-
Lin, H.1
Rathmell, J.C.2
Gray, G.S.3
Thompson, C.B.4
Leiden, J.M.5
Alegre, M.L.6
-
24
-
-
0035399732
-
CD28 independent costimulation of T cells in alloimmune responses
-
Yamada A, et al. CD28 independent costimulation of T cells in alloimmune responses. J Immunol 2001;167:140-146.
-
(2001)
J Immunol
, vol.167
, pp. 140-146
-
-
Yamada, A.1
-
25
-
-
0026459468
-
T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo
-
Turka LA, et al. T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo. Proc Natl Acad Sci USA 1992;89:11102-11105.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 11102-11105
-
-
Turka, L.A.1
-
26
-
-
0028365181
-
Transplantation tolerance induced by CTLA4-Ig
-
Pearson TC, Alexander DZ, Winn KJ, Linsley PS, Lowry RP, Larsen CP. Transplantation tolerance induced by CTLA4-Ig. Transplantation 1994;57:1701-1706.
-
(1994)
Transplantation
, vol.57
, pp. 1701-1706
-
-
Pearson, T.C.1
Alexander, D.Z.2
Winn, K.J.3
Linsley, P.S.4
Lowry, R.P.5
Larsen, C.P.6
-
27
-
-
0028903939
-
CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2
-
Sayegh MH, Akalin E, Hancock WW, Russell ME, Carpenter CB, Turka LA. CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2. J Exp Med 1995;181:1869-1874.
-
(1995)
J Exp Med
, vol.181
, pp. 1869-1874
-
-
Sayegh, M.H.1
Akalin, E.2
Hancock, W.W.3
Russell, M.E.4
Carpenter, C.B.5
Turka, L.A.6
-
28
-
-
0027451441
-
Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion
-
Lin H, et al. Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion. J Exp Med 1993;178:1801-1806.
-
(1993)
J Exp Med
, vol.178
, pp. 1801-1806
-
-
Lin, H.1
-
29
-
-
0029944669
-
CTLA4-Ig plus bone marrow induces long-term allograft survival and donor specific unresponsiveness in the murine model. Evidence for hematopoietic chimerism
-
Pearson T, et al. CTLA4-Ig plus bone marrow induces long-term allograft survival and donor specific unresponsiveness in the murine model. Evidence for hematopoietic chimerism. Transplantation 1995;61:997-1004.
-
(1995)
Transplantation
, vol.61
, pp. 997-1004
-
-
Pearson, T.1
-
30
-
-
0031464292
-
Donor antigen is necessary for the prevention of chronic rejection in CTLA4Ig-treated murine cardiac allografts
-
Sayegh M, Zheng X-G, Magee C, Hancock W, Turka L. Donor antigen is necessary for the prevention of chronic rejection in CTLA4Ig-treated murine cardiac allografts. Transplantation 1997;64:1646-1650.
-
(1997)
Transplantation
, vol.64
, pp. 1646-1650
-
-
Sayegh, M.1
Zheng, X.-G.2
Magee, C.3
Hancock, W.4
Turka, L.5
-
31
-
-
0344765483
-
Chronic blockade of CD28-B7 mediated T cell costimulation by CTLA4Ig reduces intimal thickening in MHC class I and II incompatible mouse heart allografts
-
Glysing-Jensen T, Raisanen-Sokolowski A, Sayegh MH, Russell MH. Chronic blockade of CD28-B7 mediated T cell costimulation by CTLA4Ig reduces intimal thickening in MHC class I and II incompatible mouse heart allografts. Transplantation 1997;164:1641-1645.
-
(1997)
Transplantation
, vol.164
, pp. 1641-1645
-
-
Glysing-Jensen, T.1
Raisanen-Sokolowski, A.2
Sayegh, M.H.3
Russell, M.H.4
-
32
-
-
0344613988
-
Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance
-
Li Y, Li XC, Zheng XX, Wells AD, Turka LA, Strom TB. Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance. Nat Med 1999;5:1298-1302.
-
(1999)
Nat Med
, vol.5
, pp. 1298-1302
-
-
Li, Y.1
Li, X.C.2
Zheng, X.X.3
Wells, A.D.4
Turka, L.A.5
Strom, T.B.6
-
34
-
-
0029864501
-
Blockade of T cell costimulation prevents development of experimental chronic allograft rejection
-
Azuma H, et al. Blockade of T cell costimulation prevents development of experimental chronic allograft rejection. Proc Natl Acad Sci USA 1996;93:12439-12444.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 12439-12444
-
-
Azuma, H.1
-
35
-
-
0030051268
-
Chronic cardiac rejection in the Lewis to F344 rat model: Blockade of CD28-B7 costimulation by CTLA4Ig modulates T cell and macrophage activation and attenuates arteriosclerosis
-
Russell ME, et al. Chronic cardiac rejection in the Lewis to F344 rat model: blockade of CD28-B7 costimulation by CTLA4Ig modulates T cell and macrophage activation and attenuates arteriosclerosis. J Clin Invest 1996;97:833-838.
-
(1996)
J Clin Invest
, vol.97
, pp. 833-838
-
-
Russell, M.E.1
-
36
-
-
0030890270
-
T cell costimulatory blockade in experimental chronic cardiac allograft rejection: Effects of cyclosporine and donor antigen
-
Chandraker A, Russell ME, Glysing-Jensen T, Willett TA, Sayegh MH. T cell costimulatory blockade in experimental chronic cardiac allograft rejection: effects of cyclosporine and donor antigen. Transplantation 1997;63:1053-1058.
-
(1997)
Transplantation
, vol.63
, pp. 1053-1058
-
-
Chandraker, A.1
Russell, M.E.2
Glysing-Jensen, T.3
Willett, T.A.4
Sayegh, M.H.5
-
37
-
-
0032103321
-
Late blockade of T cell costimulation interrupts progression of experimental chronic allograft rejection
-
Chandraker A, et al. Late blockade of T cell costimulation interrupts progression of experimental chronic allograft rejection. J Clin Invest 1998;101:2308-2318.
-
(1998)
J Clin Invest
, vol.101
, pp. 2308-2318
-
-
Chandraker, A.1
-
38
-
-
0000770628
-
On histocompatibility barriers, Th1 to Th2 immune deviation, and the nature of the allograft responses
-
Li XC, Zand MS, Li Y, Zheng XX, Strom TB. On histocompatibility barriers, Th1 to Th2 immune deviation, and the nature of the allograft responses. J Immunol 1998;161:2241-2247.
-
(1998)
J Immunol
, vol.161
, pp. 2241-2247
-
-
Li, X.C.1
Zand, M.S.2
Li, Y.3
Zheng, X.X.4
Strom, T.B.5
-
39
-
-
0036262969
-
Th1 cytokines, programmed cell death, and alloreactive T cell clone size in transplant tolerance
-
Kishimoto K, et al. Th1 cytokines, programmed cell death, and alloreactive T cell clone size in transplant tolerance. J Clin Invest 2002;109:1471-1479.
-
(2002)
J Clin Invest
, vol.109
, pp. 1471-1479
-
-
Kishimoto, K.1
-
40
-
-
0033215147
-
Expression of B7 molecules in recipient, not donor, mice determines the survival of cardiac allografts
-
Mandelbrot DA, et al. Expression of B7 molecules in recipient, not donor, mice determines the survival of cardiac allografts. J Immunol 1999;163:3753-3757.
-
(1999)
J Immunol
, vol.163
, pp. 3753-3757
-
-
Mandelbrot, D.A.1
-
41
-
-
0034653663
-
Absence of host B7 expression is sufficient for long-term murine vascularized heart allograft survival
-
Szot GL, et al. Absence of host B7 expression is sufficient for long-term murine vascularized heart allograft survival. Transplantation 2000;69:904-909.
-
(2000)
Transplantation
, vol.69
, pp. 904-909
-
-
Szot, G.L.1
-
42
-
-
0344510605
-
CTLA-4 plays an essential role tolerance mediated by anti-CD45RB
-
in press
-
Ariyan C, et al. CTLA-4 plays an essential role tolerance mediated by anti-CD45RB. J Immunology (in press).
-
J Immunology
-
-
Ariyan, C.1
-
43
-
-
0033579816
-
B7-1 or B7-2 is required to produce the lympho-proliferative phenotype in mice lacking cytotoxic T lymphocyte-associated antigen 4 (CTLA-4)
-
Mandelbrot D, McAdam A, Sharpe A. B7-1 or B7-2 is required to produce the lympho-proliferative phenotype in mice lacking cytotoxic T lymphocyte-associated antigen 4 (CTLA-4). J Exp Med 1999;189:435-440.
-
(1999)
J Exp Med
, vol.189
, pp. 435-440
-
-
Mandelbrot, D.1
McAdam, A.2
Sharpe, A.3
-
44
-
-
0035034067
-
-/- mice
-
-/- mice. Nat Med 2001;7:557-562.
-
(2001)
Nat Med
, vol.7
, pp. 557-562
-
-
Maier, S.1
-
45
-
-
0033198142
-
+ T cells
-
+ T cells. J Immunol 1999;163:2358-2362.
-
(1999)
J Immunol
, vol.163
, pp. 2358-2362
-
-
Newell, K.A.1
-
46
-
-
0029871741
-
The in vivo mechanisms of action of CTLA4Ig
-
Judge TA, Tang A, Spain LM, Gratiot-Deans J, Sayegh MH, Turka LA. The in vivo mechanisms of action of CTLA4Ig. J Immunol 1996;156:2294-2299.
-
(1996)
J Immunol
, vol.156
, pp. 2294-2299
-
-
Judge, T.A.1
Tang, A.2
Spain, L.M.3
Gratiot-Deans, J.4
Sayegh, M.H.5
Turka, L.A.6
-
48
-
-
0032529195
-
Impaired alloantigen-mediated T cell apoptosis and failure to induce long-term allograft survival in IL-2-deficient mice
-
Dai Z, Konieczny BT, Baddoura FK, Lakkis FG. Impaired alloantigen-mediated T cell apoptosis and failure to induce long-term allograft survival in IL-2-deficient mice. J Immunol 1998;161:1659-1663.
-
(1998)
J Immunol
, vol.161
, pp. 1659-1663
-
-
Dai, Z.1
Konieczny, B.T.2
Baddoura, F.K.3
Lakkis, F.G.4
-
49
-
-
0345476290
-
Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance
-
Wells AD, et al. Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance. Nat Med 1999;5:1303-1307.
-
(1999)
Nat Med
, vol.5
, pp. 1303-1307
-
-
Wells, A.D.1
-
50
-
-
0031307384
-
Immunosuppressive effects of hCTLA4Ig in a non-human primate model of allogeneic pancreatic islet transplantation
-
Levisetti MG, et al. Immunosuppressive effects of hCTLA4Ig in a non-human primate model of allogeneic pancreatic islet transplantation. J Immunol 1997;159:5187-5191.
-
(1997)
J Immunol
, vol.159
, pp. 5187-5191
-
-
Levisetti, M.G.1
-
51
-
-
0036061575
-
Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates
-
Adams AB, et al. Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates. Diabetes 2002;51:265-270.
-
(2002)
Diabetes
, vol.51
, pp. 265-270
-
-
Adams, A.B.1
-
52
-
-
0035967146
-
Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses
-
Stamper CC, et al. Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses. Nature 2001;410:608-611.
-
(2001)
Nature
, vol.410
, pp. 608-611
-
-
Stamper, C.C.1
-
53
-
-
0036669785
-
The interaction properties of costimulatory molecules revisited
-
Collins AV, et al. The interaction properties of costimulatory molecules revisited. Immunity 2002;17:201-210.
-
(2002)
Immunity
, vol.17
, pp. 201-210
-
-
Collins, A.V.1
-
54
-
-
0030176371
-
Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement
-
Linsley PS, Bradshaw J, Greene J, Peach R, Bennett KL, Mittler RS. Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement. Immunity 1996;4:535-543.
-
(1996)
Immunity
, vol.4
, pp. 535-543
-
-
Linsley, P.S.1
Bradshaw, J.2
Greene, J.3
Peach, R.4
Bennett, K.L.5
Mittler, R.S.6
-
55
-
-
0035056017
-
CTLA-4-mediated inhibition in regulation of T cell responses: Mechanisms and manipulation in tumor immunotherapy
-
Chambers CA, Kuhns MS, Egen JG, Allison JP. CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy. Annu Rev Immunol 2001;19:565-594.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 565-594
-
-
Chambers, C.A.1
Kuhns, M.S.2
Egen, J.G.3
Allison, J.P.4
-
56
-
-
0032403441
-
Differential role of CTLA-4 in regulation of resting memory versus naïve CD4 T cell activation
-
Metz DP, Farber DL, Taylor T, Bottomly K. Differential role of CTLA-4 in regulation of resting memory versus naïve CD4 T cell activation. J Immunol 1998;161:5855-5861.
-
(1998)
J Immunol
, vol.161
, pp. 5855-5861
-
-
Metz, D.P.1
Farber, D.L.2
Taylor, T.3
Bottomly, K.4
-
57
-
-
0033682056
-
+ immunoregulatory T cells that control autoimmune diabetes
-
+ immunoregulatory T cells that control autoimmune diabetes. Immunity 2000;12:431-440.
-
(2000)
Immunity
, vol.12
, pp. 431-440
-
-
Salomon, B.1
-
58
-
-
0034679560
-
Immunologie self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
Takahashi T, et al. Immunologie self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med 2000;192:303-310.
-
(2000)
J Exp Med
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
-
59
-
-
0030966217
-
Induction of peripheral T cell tolerance in vivo required CTLA-4 engagement
-
Perez V, Parijs LV, Biuckians A, Zheng X, Strom T, Abbas A. Induction of peripheral T cell tolerance in vivo required CTLA-4 engagement. Immunity 1997;6:411-417.
-
(1997)
Immunity
, vol.6
, pp. 411-417
-
-
Perez, V.1
Parijs, L.V.2
Biuckians, A.3
Zheng, X.4
Strom, T.5
Abbas, A.6
-
60
-
-
0029120245
-
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
-
Krummel MF, Allison JP. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J Exp Med 1995;182:459-465.
-
(1995)
J Exp Med
, vol.182
, pp. 459-465
-
-
Krummel, M.F.1
Allison, J.P.2
-
61
-
-
10744233636
-
Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152)
-
Griffin MD, et al. Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152). J Immunol 2000;164:4433-4442.
-
(2000)
J Immunol
, vol.164
, pp. 4433-4442
-
-
Griffin, M.D.1
-
62
-
-
0034658408
-
Structural analysis of CTLA-4 function in vivo
-
Masteller EL, Chuang E, Mullen AC, Reiner SL, Thompson CB. Structural analysis of CTLA-4 function in vivo. J Immunol 2000;164:5319-5327.
-
(2000)
J Immunol
, vol.164
, pp. 5319-5327
-
-
Masteller, E.L.1
Chuang, E.2
Mullen, A.C.3
Reiner, S.L.4
Thompson, C.B.5
-
63
-
-
0035803552
-
Cytotoxic T lymphocyte antigen 4 and CD28 modulate cell surface raft expression in their regulation of T cell function
-
Martin M, Schneider H, Azouz A, Rudd CE. Cytotoxic T lymphocyte antigen 4 and CD28 modulate cell surface raft expression in their regulation of T cell function. J Exp Med 2001;194:1675-1681.
-
(2001)
J Exp Med
, vol.194
, pp. 1675-1681
-
-
Martin, M.1
Schneider, H.2
Azouz, A.3
Rudd, C.E.4
-
64
-
-
0037244012
-
Negative regulation of T cell receptor-lipid raft interaction by cytotoxic T lymphocyte-associated antigen 4
-
Chikuma S, Imboden JB, Bluestone JA. Negative regulation of T cell receptor-lipid raft interaction by cytotoxic T lymphocyte-associated antigen 4. J Exp Med 2003;197:129-135.
-
(2003)
J Exp Med
, vol.197
, pp. 129-135
-
-
Chikuma, S.1
Imboden, J.B.2
Bluestone, J.A.3
-
65
-
-
0032545452
-
Molecular basis of T cell inactivation by CTLA-4
-
Lee KM, et al. Molecular basis of T cell inactivation by CTLA-4. Science 1998;282:2263-2266.
-
(1998)
Science
, vol.282
, pp. 2263-2266
-
-
Lee, K.M.1
-
66
-
-
0033985191
-
The inhibitory function of CTLA-4 does not require its tyrosine phosphorylation
-
Baroja ML, et al. The inhibitory function of CTLA-4 does not require its tyrosine phosphorylation. J Immunol 2000;164:49-55.
-
(2000)
J Immunol
, vol.164
, pp. 49-55
-
-
Baroja, M.L.1
-
67
-
-
0034607131
-
Tyrosine phosphatase SHP-2 binding to CTLA-4: Absence of direct YVKM/ YFIP motif recognition
-
Schneider H, Rudd CE. Tyrosine phosphatase SHP-2 binding to CTLA-4: absence of direct YVKM/YFIP motif recognition. Biochem Biophys Res Commun 2000;269:279-283.
-
(2000)
Biochem Biophys Res Commun
, vol.269
, pp. 279-283
-
-
Schneider, H.1
Rudd, C.E.2
-
68
-
-
0037093856
-
Inhibition of CTLA-4 function by the regulatory subunit of serine/threonine phosphatase 2A
-
Baroja ML, et al. Inhibition of CTLA-4 function by the regulatory subunit of serine/threonine phosphatase 2A. J Immunol 2002;168:5070-5078.
-
(2002)
J Immunol
, vol.168
, pp. 5070-5078
-
-
Baroja, M.L.1
-
69
-
-
0036784602
-
Physiological mechanisms of regulating alloimmunity: Cytokines, CTLA-4, CD25(+) cells, and the alloreactive T cell done size
-
Sho M, et al. Physiological mechanisms of regulating alloimmunity: cytokines, CTLA-4, CD25(+) cells, and the alloreactive T cell done size. J Immunol 2002;169:3744-3751.
-
(2002)
J Immunol
, vol.169
, pp. 3744-3751
-
-
Sho, M.1
-
70
-
-
0033557716
-
The role of CD80, CD86, and CTLA4 in alloimmune responses and the induction of long-term allograft survival
-
Judge TA, Wu Z, Zheng XG, Sharpe AH, Sayegh MH, Turka LA. The role of CD80, CD86, and CTLA4 in alloimmune responses and the induction of long-term allograft survival. J Immunol 1999;162:1947-1951.
-
(1999)
J Immunol
, vol.162
, pp. 1947-1951
-
-
Judge, T.A.1
Wu, Z.2
Zheng, X.G.3
Sharpe, A.H.4
Sayegh, M.H.5
Turka, L.A.6
-
71
-
-
0004880266
-
CTLA4 signals are required to optimally induce allograft tolerance with combined DST and anti-CD 154 mAb treatment
-
Zheng XX, et al. CTLA4 signals are required to optimally induce allograft tolerance with combined DST and anti-CD 154 mAb treatment. J Immunol 1999;162:4983-4990.
-
(1999)
J Immunol
, vol.162
, pp. 4983-4990
-
-
Zheng, X.X.1
-
72
-
-
0035880243
-
Requirements for the promotion of allogeneic engraftment by anti-CD 154 (anti-CD40L) monoclonal antibody under nonmyeloablative conditions
-
Taylor PA, Lees CJ, Waldmann H, Noelle RJ, Blazar BR. Requirements for the promotion of allogeneic engraftment by anti-CD 154 (anti-CD40L) monoclonal antibody under nonmyeloablative conditions. Blood 2001;98:467-474.
-
(2001)
Blood
, vol.98
, pp. 467-474
-
-
Taylor, P.A.1
Lees, C.J.2
Waldmann, H.3
Noelle, R.J.4
Blazar, B.R.5
-
73
-
-
0037100256
-
Cutting edge: Targeted ligation of CTLA-4 in vivo by membrane-bound anti-CTLA-4 antibody prevents rejection of allogeneic cells
-
Hwang KW, et al. Cutting edge: targeted ligation of CTLA-4 in vivo by membrane-bound anti-CTLA-4 antibody prevents rejection of allogeneic cells. J Immunol 2002;169:633-637.
-
(2002)
J Immunol
, vol.169
, pp. 633-637
-
-
Hwang, K.W.1
-
74
-
-
0035236195
-
CTLA-4 upregulation plays a role in tolerance mediated by CD45
-
Fecteau S, Basadonna GP, Freitas A, Ariyan C, Sayegh MH, Rothstein DM. CTLA-4 upregulation plays a role in tolerance mediated by CD45. Nat Immunol 2001;2:58-63.
-
(2001)
Nat Immunol
, vol.2
, pp. 58-63
-
-
Fecteau, S.1
Basadonna, G.P.2
Freitas, A.3
Ariyan, C.4
Sayegh, M.H.5
Rothstein, D.M.6
-
75
-
-
0035159495
-
Targeting signal 1 through CD45RB synergizes with CD40 ligand blockade and promotes long term engraftment and tolerance in stringent transplant models
-
Rothstein DM, et al. Targeting signal 1 through CD45RB synergizes with CD40 ligand blockade and promotes long term engraftment and tolerance in stringent transplant models. J Immunol 2001;166:322-329.
-
(2001)
J Immunol
, vol.166
, pp. 322-329
-
-
Rothstein, D.M.1
-
76
-
-
0035092850
-
CD28-independent induction of experimental autoimmune encephalomyelitis
-
Chitnis T, et al. CD28-independent induction of experimental autoimmune encephalomyelitis. J Clin Invest 2001;107:575-583.
-
(2001)
J Clin Invest
, vol.107
, pp. 575-583
-
-
Chitnis, T.1
-
77
-
-
0028826268
-
Inhibition of transplant rejection following treatment with anti-B7-2 and anti-B7-1 antibodies
-
Lenschow DJ, et al. Inhibition of transplant rejection following treatment with anti-B7-2 and anti-B7-1 antibodies. Transplantation 1995;60:1171-1178.
-
(1995)
Transplantation
, vol.60
, pp. 1171-1178
-
-
Lenschow, D.J.1
-
78
-
-
0030474264
-
Costimulatory function of CD40L, CD80 and CD86 in vascularized murine cardiac allograft rejection
-
Hancock WW, Sayegh MH, Peach R, Linsley PS, Turka LA. Costimulatory function of CD40L, CD80 and CD86 in vascularized murine cardiac allograft rejection. Proc Natl Acad Sci USA 1996;93:13967-13972.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13967-13972
-
-
Hancock, W.W.1
Sayegh, M.H.2
Peach, R.3
Linsley, P.S.4
Turka, L.A.5
-
79
-
-
0031203940
-
The role of donor and recipient B7-1 (CD80) in allograft rejection
-
Zheng XX, et al. The role of donor and recipient B7-1 (CD80) in allograft rejection. J Immunol 1997;159:1169-1173.
-
(1997)
J Immunol
, vol.159
, pp. 1169-1173
-
-
Zheng, X.X.1
-
80
-
-
0035057078
-
B7-dependent T-cell costimulation in mice lacking CD28 and CTLA4
-
Mandelbrot DA, et al. B7-dependent T-cell costimulation in mice lacking CD28 and CTLA4. J Clin Invest 2001;107:881-887.
-
(2001)
J Clin Invest
, vol.107
, pp. 881-887
-
-
Mandelbrot, D.A.1
-
81
-
-
0033888919
-
Association of B7-1 co-stimulation with the development of graft arterial disease. Studies using mice lacking B7-1, B7-2, or B7-1/B7-2
-
Furukawa Y, Mandelbrot DA, Libby P, Sharpe AH, Mitchell RN. Association of B7-1 co-stimulation with the development of graft arterial disease. Studies using mice lacking B7-1, B7-2, or B7-1/B7-2. Am J Pathol 2000;157:473-484.
-
(2000)
Am J Pathol
, vol.157
, pp. 473-484
-
-
Furukawa, Y.1
Mandelbrot, D.A.2
Libby, P.3
Sharpe, A.H.4
Mitchell, R.N.5
-
82
-
-
0035101515
-
CD28-B7-mediated T cell costimulation in chronic cardiac allograft rejection: Differential role of B7-1 in initiation versus progression of graft arteriosclerosis
-
Kim KS, et al. CD28-B7-mediated T cell costimulation in chronic cardiac allograft rejection: differential role of B7-1 in initiation versus progression of graft arteriosclerosis. Am J Pathol 2001;158:977-986.
-
(2001)
Am J Pathol
, vol.158
, pp. 977-986
-
-
Kim, K.S.1
-
83
-
-
0036852170
-
CTLA-4-1g regulates tryptophan catabolism in vivo
-
Grohmann U, et al. CTLA-4-1g regulates tryptophan catabolism in vivo. Nat Immunol 2002;3:1097-1101.
-
(2002)
Nat Immunol
, vol.3
, pp. 1097-1101
-
-
Grohmann, U.1
-
84
-
-
0033215041
-
Tryptophan catabolism and T-cell tolerance: Immunosuppression by starvation?
-
Mellor AL, Munn DH. Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation? Immunol Today 1999;20:469-473.
-
(1999)
Immunol Today
, vol.20
, pp. 469-473
-
-
Mellor, A.L.1
Munn, D.H.2
-
85
-
-
0035889926
-
Recipient MHC class II expression is required to achieve long-term survival of murine cardiac allografts after costimulatory blockade
-
Yamada A, Chandraker A, Laufer TM, Gerth AJ, Sayegh MH, Auchincloss H Jr. Recipient MHC class II expression is required to achieve long-term survival of murine cardiac allografts after costimulatory blockade. J Immunol 2001;167:5522-5526.
-
(2001)
J Immunol
, vol.167
, pp. 5522-5526
-
-
Yamada, A.1
Chandraker, A.2
Laufer, T.M.3
Gerth, A.J.4
Sayegh, M.H.5
Auchincloss Jr., H.6
-
86
-
-
0037080947
-
The CD154-CD40 costimulatory pathway in transplantation
-
Yamada A, Sayegh MH. The CD154-CD40 costimulatory pathway in transplantation. Transplantation 2002;73:S36-S39.
-
(2002)
Transplantation
, vol.73
-
-
Yamada, A.1
Sayegh, M.H.2
-
87
-
-
0036461018
-
The role of TNF receptor and TNF superfamily molecules in organ transplantation
-
Adams AB, Larsen CP, Pearson TC, Newell KA. The role of TNF receptor and TNF superfamily molecules in organ transplantation. Am J Transplant 2002;2:12-18.
-
(2002)
Am J Transplant
, vol.2
, pp. 12-18
-
-
Adams, A.B.1
Larsen, C.P.2
Pearson, T.C.3
Newell, K.A.4
-
88
-
-
0034695882
-
CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis
-
Blair PJ, et al. CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis. J Exp Med 2000;191:651-660.
-
(2000)
J Exp Med
, vol.191
, pp. 651-660
-
-
Blair, P.J.1
-
89
-
-
0028790434
-
CD40 ligand-transduced co-stimulation of T cells in the development of helper function
-
van Essen D, Kikutani H, Gray D. CD40 ligand-transduced co-stimulation of T cells in the development of helper function. Nature 1995;378:620-623.
-
(1995)
Nature
, vol.378
, pp. 620-623
-
-
Van Essen, D.1
Kikutani, H.2
Gray, D.3
-
90
-
-
0027414691
-
CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome
-
Allen RC, et al. CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome. Science 1993;259:990-993.
-
(1993)
Science
, vol.259
, pp. 990-993
-
-
Allen, R.C.1
-
92
-
-
0028882526
-
Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand
-
Parker DC, et al. Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand. Proc Natl Acad Sci USA 1995;92:9560-9564.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9560-9564
-
-
Parker, D.C.1
-
93
-
-
0036378101
-
Immature, but not inactive: The tolerogenic function of immature dendritic cells
-
Mahnke K, Schmitt E, Bonifaz L, Enk AH, Jonuleit H. Immature, but not inactive: the tolerogenic function of immature dendritic cells. Immunol Cell Biol 2002;80:477-483.
-
(2002)
Immunol Cell Biol
, vol.80
, pp. 477-483
-
-
Mahnke, K.1
Schmitt, E.2
Bonifaz, L.3
Enk, A.H.4
Jonuleit, H.5
-
94
-
-
0036658721
-
Mechanisms of TNF receptor-associated factor (TRAF) regulation in B lymphocytes
-
Bishop GA, Hostager BS, Brown KD. Mechanisms of TNF receptor-associated factor (TRAF) regulation in B lymphocytes. J Leukoc Biol 2002;72:19-23.
-
(2002)
J Leukoc Biol
, vol.72
, pp. 19-23
-
-
Bishop, G.A.1
Hostager, B.S.2
Brown, K.D.3
-
95
-
-
0035475338
-
Tumor necrosis factor receptor-associated factors (TRAFs)
-
Bradley JR, Pober JS. Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene 2001;20:6482-6491.
-
(2001)
Oncogene
, vol.20
, pp. 6482-6491
-
-
Bradley, J.R.1
Pober, J.S.2
-
96
-
-
0033151951
-
Cutting edge: Contrasting roles of TNF receptor-associated factor 2 (TRAF2) and TRAF3 in CD40-activated B lymphocyte differentiation
-
Hostager BS, Bishop GA. Cutting edge: contrasting roles of TNF receptor-associated factor 2 (TRAF2) and TRAF3 in CD40-activated B lymphocyte differentiation. J Immunol 1999;162:6307-6311.
-
(1999)
J Immunol
, vol.162
, pp. 6307-6311
-
-
Hostager, B.S.1
Bishop, G.A.2
-
97
-
-
0030046808
-
CD40-gp39 interactions play a critical role during allograft rejection: Suppression of allograft rejection by blockade of the CD40-gp39 pathway
-
Larsen CP, et al. CD40-gp39 interactions play a critical role during allograft rejection: suppression of allograft rejection by blockade of the CD40-gp39 pathway. Transplantation 1996;61:4-9.
-
(1996)
Transplantation
, vol.61
, pp. 4-9
-
-
Larsen, C.P.1
-
98
-
-
0036829074
-
New insights into the interactions between T cell costimulatory blockade and conventional immunosuppressive drugs
-
Sho M, et al. New insights into the interactions between T cell costimulatory blockade and conventional immunosuppressive drugs. Ann Surg 2002;236:667-675.
-
(2002)
Ann Surg
, vol.236
, pp. 667-675
-
-
Sho, M.1
-
99
-
-
12644262358
-
CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates
-
Kirk AD, et al. CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates. Proc Natl Acad Sci USA 1997;94:8789-8794.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8789-8794
-
-
Kirk, A.D.1
-
100
-
-
0032996025
-
Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates
-
Kirk AD, et al. Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates. Nat Med 1999;5:686-693.
-
(1999)
Nat Med
, vol.5
, pp. 686-693
-
-
Kirk, A.D.1
-
101
-
-
0033529235
-
Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154
-
Kenyon NS, et al. Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154. Proc Natl Acad Sci USA 1999;96:8132-8137.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 8132-8137
-
-
Kenyon, N.S.1
-
102
-
-
0033056692
-
Long-term survival and function of intrahepatic islet allografts in baboons treated with humanized anti-CD154
-
Kenyon NS, et al. Long-term survival and function of intrahepatic islet allografts in baboons treated with humanized anti-CD154. Diabetes 1999;48:1473-1481.
-
(1999)
Diabetes
, vol.48
, pp. 1473-1481
-
-
Kenyon, N.S.1
-
103
-
-
0034720744
-
+ T cells contribute to the development of transplant arteriosclerosis despite CD154 blockade
-
+ T cells contribute to the development of transplant arteriosclerosis despite CD154 blockade. Transplantation 2000;69:2609-2612.
-
(2000)
Transplantation
, vol.69
, pp. 2609-2612
-
-
Ensminger, S.M.1
-
104
-
-
0034665321
-
Host CD40 ligand deficiency induces long-term allograft survival and donor-specific tolerance in mouse cardiac transplantation but does not prevent graft arteriosclerosis
-
Shimizu K, Schonbeck U, Mach F, Libby P, Mitchell RN. Host CD40 ligand deficiency induces long-term allograft survival and donor-specific tolerance in mouse cardiac transplantation but does not prevent graft arteriosclerosis. J Immunol 2000;165:3506-3518.
-
(2000)
J Immunol
, vol.165
, pp. 3506-3518
-
-
Shimizu, K.1
Schonbeck, U.2
Mach, F.3
Libby, P.4
Mitchell, R.N.5
-
105
-
-
0031757984
-
Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes
-
Hancock WW, Buelow R, Sayegh MH, Turka LA. Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes. Nat Med 1998;4:1392-1396.
-
(1998)
Nat Med
, vol.4
, pp. 1392-1396
-
-
Hancock, W.W.1
Buelow, R.2
Sayegh, M.H.3
Turka, L.A.4
-
106
-
-
15844404353
-
Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways
-
Larsen CP, et al. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways. Nature 1996;381:434-438.
-
(1996)
Nature
, vol.381
, pp. 434-438
-
-
Larsen, C.P.1
-
107
-
-
0037469016
-
CD45RB-targeting strategies for promoting long-term allograft survival and preventingchronic allograft vasculopathy
-
Sho M, Harada H, Rothstein DM, Sayegh MH. CD45RB-targeting strategies for promoting long-term allograft survival and preventingchronic allograft vasculopathy. Transplantation 2003;75:1142-1146.
-
(2003)
Transplantation
, vol.75
, pp. 1142-1146
-
-
Sho, M.1
Harada, H.2
Rothstein, D.M.3
Sayegh, M.H.4
-
108
-
-
0037096606
-
A novel CD154 monoclonal antibody in acute and chronicrat vascularized cardiac allograft rejection
-
Yuan X, et al. A novel CD154 monoclonal antibody in acute and chronicrat vascularized cardiac allograft rejection. Transplantation 2002;73:1736-1742.
-
(2002)
Transplantation
, vol.73
, pp. 1736-1742
-
-
Yuan, X.1
-
110
-
-
0032526283
-
Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance
-
Wekerle T, et al. Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance. J Exp Med 1998;187:2037-2044.
-
(1998)
J Exp Med
, vol.187
, pp. 2037-2044
-
-
Wekerle, T.1
-
111
-
-
0034071426
-
Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreducutive host treatment
-
Wekerle T, et al. Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreducutive host treatment. Nat Med 2000;6:464-469.
-
(2000)
Nat Med
, vol.6
, pp. 464-469
-
-
Wekerle, T.1
-
112
-
-
0034235458
-
Cutting edge: Administration of anti-CD40 ligand and donor bone marrow leads to hemopoietic chimerism and donor-specific tolerance without cytoreductive conditioning
-
Durham MM, et al. Cutting edge: administration of anti-CD40 ligand and donor bone marrow leads to hemopoietic chimerism and donor-specific tolerance without cytoreductive conditioning. J Immunol 2000;165:1-4.
-
(2000)
J Immunol
, vol.165
, pp. 1-4
-
-
Durham, M.M.1
-
113
-
-
0035806276
-
CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade
-
Taylor PA, Noelle RJ, Blazar BR. CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade. J Exp Med 2001;193:1311-1318.
-
(2001)
J Exp Med
, vol.193
, pp. 1311-1318
-
-
Taylor, P.A.1
Noelle, R.J.2
Blazar, B.R.3
-
114
-
-
0033965079
-
Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand
-
Kawai T, Andrews D, Colvin RB, Sachs DH, Cosimi AB. Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand. Nat Med 2000;6:114.
-
(2000)
Nat Med
, vol.6
, pp. 114
-
-
Kawai, T.1
Andrews, D.2
Colvin, R.B.3
Sachs, D.H.4
Cosimi, A.B.5
-
115
-
-
0033590502
-
ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
-
Hutloff A, et al. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature 1999;397:263-266.
-
(1999)
Nature
, vol.397
, pp. 263-266
-
-
Hutloff, A.1
-
116
-
-
0033576707
-
T-cell co-stimulation through B7RP-1 and ICOS
-
Yoshinaga SK, et al. T-cell co-stimulation through B7RP-1 and ICOS. Nature 1999;402:827-832.
-
(1999)
Nature
, vol.402
, pp. 827-832
-
-
Yoshinaga, S.K.1
-
117
-
-
0034704760
-
LICOS, a primordial costimulatory ligand?
-
Brodie D, et al. LICOS, a primordial costimulatory ligand? Curr Biol 2000;10:333-336.
-
(2000)
Curr Biol
, vol.10
, pp. 333-336
-
-
Brodie, D.1
-
118
-
-
0033212778
-
B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNF-alpha
-
Swallow MM, Wallin JJ, Sha WC. B7h, a novel costimulatory homolog of B7. 1 and B7.2, is induced by TNF-alpha. Immunity 1999;11:423-432.
-
(1999)
Immunity
, vol.11
, pp. 423-432
-
-
Swallow, M.M.1
Wallin, J.J.2
Sha, W.C.3
-
119
-
-
0033809736
-
Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS
-
Yoshinaga SK, et al. Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS. Int Immunol 2000;12:1439-1447.
-
(2000)
Int Immunol
, vol.12
, pp. 1439-1447
-
-
Yoshinaga, S.K.1
-
120
-
-
0034651694
-
Cutting edge: Identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor
-
Ling V, et al. Cutting edge: identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor. J Immunol 2000;164:1653-1657.
-
(2000)
J Immunol
, vol.164
, pp. 1653-1657
-
-
Ling, V.1
-
121
-
-
0033999501
-
Molecular cloning and characterization of murine ICOS and identification of B7h as ICOS ligand
-
Mages HW, et al. Molecular cloning and characterization of murine ICOS and identification of B7h as ICOS ligand. Eur J Immunol 2000;30:1040-1047.
-
(2000)
Eur J Immunol
, vol.30
, pp. 1040-1047
-
-
Mages, H.W.1
-
122
-
-
0034193043
-
Characterization of human inducible costimulator ligand expression and function
-
Aicher A, et al. Characterization of human inducible costimulator ligand expression and function. J Immunol 2000;164:4689-4696.
-
(2000)
J Immunol
, vol.164
, pp. 4689-4696
-
-
Aicher, A.1
-
123
-
-
0033696961
-
The CD28-related molecule ICOS is required for effective T cell-dependent immune responses
-
Coyle AJ, et al. The CD28-related molecule ICOS is required for effective T cell-dependent immune responses. Immunity 2000;13:95-105.
-
(2000)
Immunity
, vol.13
, pp. 95-105
-
-
Coyle, A.J.1
-
124
-
-
0034327808
-
Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4(+) T cells
-
McAdam AJ, et al. Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4(+) T cells. J Immunol 2000;165:5035-5040.
-
(2000)
J Immunol
, vol.165
, pp. 5035-5040
-
-
McAdam, A.J.1
-
125
-
-
0033018101
-
T cell co-stimulatory molecules other than CD28
-
Watts TH, DeBenedette MA. T cell co-stimulatory molecules other than CD28. Curr Opin Immunol 1999;11:286-293.
-
(1999)
Curr Opin Immunol
, vol.11
, pp. 286-293
-
-
Watts, T.H.1
DeBenedette, M.A.2
-
126
-
-
0036732461
-
Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
-
Akbari O, et al. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat Med 2002;8:1024-1032.
-
(2002)
Nat Med
, vol.8
, pp. 1024-1032
-
-
Akbari, O.1
-
127
-
-
0034600567
-
Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection
-
Kopf M, et al. Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection. J Exp Med 2000;192:53-61.
-
(2000)
J Exp Med
, vol.192
, pp. 53-61
-
-
Kopf, M.1
-
128
-
-
0035804254
-
ICOS co-stimulatory receptor is essential for T-cell activation and function
-
Dong C, et al. ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature 2001;409:97-101.
-
(2001)
Nature
, vol.409
, pp. 97-101
-
-
Dong, C.1
-
129
-
-
0035804268
-
ICOS is critical for CD40-mediated antibody class switching
-
McAdam AJ, et al. ICOS is critical for CD40-mediated antibody class switching. Nature 2001;409:102-105.
-
(2001)
Nature
, vol.409
, pp. 102-105
-
-
McAdam, A.J.1
-
130
-
-
0035804269
-
ICOS is essential for effective T-helper-cell responses
-
Tafuri A, et al. ICOS is essential for effective T-helper-cell responses. Nature 2001;409:105-109.
-
(2001)
Nature
, vol.409
, pp. 105-109
-
-
Tafuri, A.1
-
131
-
-
0034917195
-
Importance ICOS-B7RP-1 costimulation in acute and chronic allograft rejection
-
Ozkaynak E, et al. Importance ICOS-B7RP-1 costimulation in acute and chronic allograft rejection. Nat Immunol 2001;2:591-596.
-
(2001)
Nat Immunol
, vol.2
, pp. 591-596
-
-
Ozkaynak, E.1
-
132
-
-
0043245118
-
The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity
-
Harada H, et al. The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity. J Clin Invest 2003;112:234-243.
-
(2003)
J Clin Invest
, vol.112
, pp. 234-243
-
-
Harada, H.1
-
133
-
-
0034922160
-
The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE
-
Rottman JB, et al. The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE. Nat Immunol 2001;2:605-611.
-
(2001)
Nat Immunol
, vol.2
, pp. 605-611
-
-
Rottman, J.B.1
-
134
-
-
0035340798
-
CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A
-
Shlapatska LM, et al. CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A. J Immunol 2001;166:5480-5487.
-
(2001)
J Immunol
, vol.166
, pp. 5480-5487
-
-
Shlapatska, L.M.1
-
135
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman G, et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000;192:1-9.
-
(2000)
J Exp Med
, vol.192
, pp. 1-9
-
-
Freeman, G.1
-
136
-
-
5844264920
-
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
-
Latchman Y, et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol 2001;2:261-268.
-
(2001)
Nat Immunol
, vol.2
, pp. 261-268
-
-
Latchman, Y.1
-
137
-
-
0037152153
-
Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues
-
Ishida M, et al. Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues. Immunol Lett 2002;84:57-62.
-
(2002)
Immunol Lett
, vol.84
, pp. 57-62
-
-
Ishida, M.1
-
138
-
-
0037477604
-
Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis
-
Salama A, et al. Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis. J Exp Med 2003;198:71-78.
-
(2003)
J Exp Med
, vol.198
, pp. 71-78
-
-
Salama, A.1
-
139
-
-
0037477605
-
The programmed death-1 (PD-1) regulatory pathway regulates autoimmune diabetes in NOD mice
-
Ansari MJ, et al. The programmed death-1 (PD-1) regulatory pathway regulates autoimmune diabetes in NOD mice. J Exp Med 2003;198:63-39.
-
(2003)
J Exp Med
, vol.198
, pp. 63-139
-
-
Ansari, M.J.1
-
140
-
-
0036207926
-
PD-1: PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2
-
Carter L, et al. PD-1: PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2. Eur J Immunol 2002;32:634-643.
-
(2002)
Eur J Immunol
, vol.32
, pp. 634-643
-
-
Carter, L.1
-
141
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
Nishimura H, Nose M, Hiai H, Minato N, Honjo T. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 1999;11:141-151.
-
(1999)
Immunity
, vol.11
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
142
-
-
0031685190
-
Immunological studies on PD-1 deficient mice: Implication of PD-1 as a negative regulator for B cell responses
-
Nishimura H, Minato N, Nakano T, Honjo T. Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses. Int Immunol 1998;10:1563-1572.
-
(1998)
Int Immunol
, vol.10
, pp. 1563-1572
-
-
Nishimura, H.1
Minato, N.2
Nakano, T.3
Honjo, T.4
-
143
-
-
0032736029
-
B7-H1, a third member of the B7 family, costimulates T cell proliferation and interleukin-10 secretion
-
Dong H, Zhu G, Tamada K, Chen L. B7-H1, a third member of the B7 family, costimulates T cell proliferation and interleukin-10 secretion. Nat Med 1999;5:1365-1369.
-
(1999)
Nat Med
, vol.5
, pp. 1365-1369
-
-
Dong, H.1
Zhu, G.2
Tamada, K.3
Chen, L.4
-
144
-
-
0035794314
-
B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
-
Tseng SY, et al. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med 2001;193:839-846.
-
(2001)
J Exp Med
, vol.193
, pp. 839-846
-
-
Tseng, S.Y.1
-
145
-
-
0034927194
-
PD-1: An inhibitory immunoreceptor involved in peripheral tolerance
-
Nishimura H, Honjo T. PD-1: an inhibitory immunoreceptor involved in peripheral tolerance. Trends Immunol 2001;22:265-268.
-
(2001)
Trends Immunol
, vol.22
, pp. 265-268
-
-
Nishimura, H.1
Honjo, T.2
-
146
-
-
0035846991
-
Autoimmune dilated cardiomyopathy in PD-1 receptor deficient mice
-
Nishimura H, et al. Autoimmune dilated cardiomyopathy in PD-1 receptor deficient mice. Science 2001;291:319-322.
-
(2001)
Science
, vol.291
, pp. 319-322
-
-
Nishimura, H.1
-
147
-
-
0035923535
-
PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine
-
Okazaki T, Maeda A, Nishimura H, Kurosaki T, Honjo T. PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine. Proc Natl Acad Sci USA 2001;98:13866-13871.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13866-13871
-
-
Okazaki, T.1
Maeda, A.2
Nishimura, H.3
Kurosaki, T.4
Honjo, T.5
-
148
-
-
0036884356
-
Programmed death-1 targeting can promote allograft survival
-
Ozkaynak E, et al. Programmed death-1 targeting can promote allograft survival. J Immunol 2002;169:6546-6553.
-
(2002)
J Immunol
, vol.169
, pp. 6546-6553
-
-
Ozkaynak, E.1
-
149
-
-
0141433189
-
Stimulating PD-1 negative signals concurrent with blocking CD154 costimulation induces long-term allograft survival
-
Gao W, Demirci G, Strom TB, Li XC. Stimulating PD-1 negative signals concurrent with blocking CD154 costimulation induces long-term allograft survival. Transplantation 2003;76:994-999.
-
(2003)
Transplantation
, vol.76
, pp. 994-999
-
-
Gao, W.1
Demirci, G.2
Strom, T.B.3
Li, X.C.4
-
150
-
-
0345372781
-
The role of the inhibitory costimulatory pathway PD-1 in regulating alloimmune responses in vivo
-
Ito T, Nayer A, Yagita H, Auchincloss H Jr, Sayegh MH. The role of the inhibitory costimulatory pathway PD-1 in regulating alloimmune responses in vivo [Abstract]. Am J Transplant 2003;3:169.
-
(2003)
Am J Transplant
, vol.3
, pp. 169
-
-
Ito, T.1
Nayer, A.2
Yagita, H.3
Auchincloss Jr., H.4
Sayegh, M.H.5
-
151
-
-
0041845131
-
Blockade of PD-1 pathway engagement accelerates graft-versus-host disease lethality
-
Blazar BR, et al. Blockade of PD-1 pathway engagement accelerates graft-versus-host disease lethality. J Immunol 2003;171:1272-1277.
-
(2003)
J Immunol
, vol.171
, pp. 1272-1277
-
-
Blazar, B.R.1
-
152
-
-
0023503073
-
Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts
-
Paterson DJ, et al. Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. Mol Immunol 1987;24:1281-1290.
-
(1987)
Mol Immunol
, vol.24
, pp. 1281-1290
-
-
Paterson, D.J.1
-
153
-
-
0025320534
-
Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes - A molecule related to nerve growth factor receptor
-
Mallett S, Fossum S, Barclay AN. Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes - a molecule related to nerve growth factor receptor. EMBO J 1990;9:1063-1068.
-
(1990)
EMBO J
, vol.9
, pp. 1063-1068
-
-
Mallett, S.1
Fossum, S.2
Barclay, A.N.3
-
154
-
-
0027383870
-
Cloning of mouse Ox40: A T cell activation marker that may mediate T-B cell interactions
-
Calderhead DM, Buhlmann JE, van den Eertwegh AJ, Claassen E, Noelle RJ, Fell HP. Cloning of mouse Ox40: a T cell activation marker that may mediate T-B cell interactions. J Immunol 1993;151:5261-5271.
-
(1993)
J Immunol
, vol.151
, pp. 5261-5271
-
-
Calderhead, D.M.1
Buhlmann, J.E.2
Van Den Eertwegh, A.J.3
Claassen, E.4
Noelle, R.J.5
Fell, H.P.6
-
155
-
-
0028297408
-
The human OX40 homolog: cDNA structure, expression and chromosomal assignment of the ACT35 antigen
-
Latza U, et al. The human OX40 homolog: cDNA structure, expression and chromosomal assignment of the ACT35 antigen. Eur J Immunol 1994;24:677-683.
-
(1994)
Eur J Immunol
, vol.24
, pp. 677-683
-
-
Latza, U.1
-
156
-
-
0026030090
-
Molecular cloning and characterization of a novel glycoprotein, gp34, that is specifically induced by the human T-cell leukemia virus type I transactivator p40tax
-
Miura S, et al. Molecular cloning and characterization of a novel glycoprotein, gp34, that is specifically induced by the human T-cell leukemia virus type I transactivator p40tax. Mol Cell Biol 1991;11:1313-1325.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 1313-1325
-
-
Miura, S.1
-
157
-
-
0028023305
-
Molecular characterization of murine and human OX40/OX40 ligand systems: Identification of a human OX40 ligand as the HTLV-1-regulated protein gp34
-
Baum PR, et al. Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34. EMBO J 1994;13:3992-4001.
-
(1994)
EMBO J
, vol.13
, pp. 3992-4001
-
-
Baum, P.R.1
-
159
-
-
0028853808
-
Expression of the human OX40 (hOX40) antigen in normal and neoplastic tissues
-
Durkop H, Latza U, Himmelreich P, Stein H. Expression of the human OX40 (hOX40) antigen in normal and neoplastic tissues. Br J Haematol 1995;91:927-931.
-
(1995)
Br J Haematol
, vol.91
, pp. 927-931
-
-
Durkop, H.1
Latza, U.2
Himmelreich, P.3
Stein, H.4
-
160
-
-
0032534582
-
Ox-40 ligand: A potent costimulatory molecule for sustaining primary CD4 T cell responses
-
Gramaglia I, Weinberg AD, Lemon M, Croft M. Ox-40 ligand: a potent costimulatory molecule for sustaining primary CD4 T cell responses. J Immunol 1998;161:6510-6517.
-
(1998)
J Immunol
, vol.161
, pp. 6510-6517
-
-
Gramaglia, I.1
Weinberg, A.D.2
Lemon, M.3
Croft, M.4
-
161
-
-
0028211518
-
Target organ-specific upregulation of the MRC OX-40 marker and selective production of Th1 lymphokine mRNA by encephalitogenic T helper cells isolated from the spinal cord of rats with experimental autoimmune encephalomyelitis
-
Weinberg AD, et al. Target organ-specific upregulation of the MRC OX-40 marker and selective production of Th1 lymphokine mRNA by encephalitogenic T helper cells isolated from the spinal cord of rats with experimental autoimmune encephalomyelitis. J Immunol 1994;152:4712-4721.
-
(1994)
J Immunol
, vol.152
, pp. 4712-4721
-
-
Weinberg, A.D.1
-
162
-
-
0032753621
-
Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers
-
Walker LS, et al. Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers. J Exp Med 1999;190:1115-1122.
-
(1999)
J Exp Med
, vol.190
, pp. 1115-1122
-
-
Walker, L.S.1
-
163
-
-
0029045255
-
Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells
-
Stuber E, Neurath M, Calderhead D, Fell HP, Strober W. Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells. Immunity 1995;2:507-521.
-
(1995)
Immunity
, vol.2
, pp. 507-521
-
-
Stuber, E.1
Neurath, M.2
Calderhead, D.3
Fell, H.P.4
Strober, W.5
-
164
-
-
0031572569
-
Expression and function of OX40 ligand on human dendritic cells
-
Ohshima Y, Tanaka Y, Tozawa H, Takahashi Y, Maliszewski C, Delespesse G. Expression and function of OX40 ligand on human dendritic cells. J Immunol 1997;159:3838-3848.
-
(1997)
J Immunol
, vol.159
, pp. 3838-3848
-
-
Ohshima, Y.1
Tanaka, Y.2
Tozawa, H.3
Takahashi, Y.4
Maliszewski, C.5
Delespesse, G.6
-
165
-
-
0029895222
-
The human OX40/gp34 system directly mediates adhesion of activated T cells to vascular endothelial cells
-
Imura A, et al. The human OX40/gp34 system directly mediates adhesion of activated T cells to vascular endothelial cells. J Exp Med 1996;183:2185-2195.
-
(1996)
J Exp Med
, vol.183
, pp. 2185-2195
-
-
Imura, A.1
-
168
-
-
0034665502
-
The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion
-
Gramaglia I, Jember A, Pippig SD, Weinberg AD, Killeen N, Croft M. The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion. J Immunol 2000;165:3043-3050.
-
(2000)
J Immunol
, vol.165
, pp. 3043-3050
-
-
Gramaglia, I.1
Jember, A.2
Pippig, S.D.3
Weinberg, A.D.4
Killeen, N.5
Croft, M.6
-
169
-
-
0033427044
-
Ox40-ligand has a critical costimulatory role in dendritic cell: T cell interactions
-
Chen AI, et al. Ox40-ligand has a critical costimulatory role in dendritic cell: T cell interactions. Immunity 1999;11:689-698.
-
(1999)
Immunity
, vol.11
, pp. 689-698
-
-
Chen, A.I.1
-
170
-
-
0033427047
-
OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL responses after virus infection
-
Kopf M, et al. OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL responses after virus infection. Immunity 1999;11:699-708.
-
(1999)
Immunity
, vol.11
, pp. 699-708
-
-
Kopf, M.1
-
171
-
-
0344286707
-
Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40)
-
Pippig SD, et al. Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40). J Immunol 1999;163:6520-6529.
-
(1999)
J Immunol
, vol.163
, pp. 6520-6529
-
-
Pippig, S.D.1
-
172
-
-
0034677176
-
Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand
-
Murata K, et al. Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand. J Exp Med 2000;191:365-374.
-
(2000)
J Exp Med
, vol.191
, pp. 365-374
-
-
Murata, K.1
-
173
-
-
0031872028
-
CD4 T cell cytokine differentiation: The B cell activation molecule, OX40 ligand, instructs CD4 T cells to express interleukin 4 and upregulates expression of the chemokine receptor, Blr-1
-
Flynn S, Toellner KM, Raykundalia C, Goodall M, Lane P. CD4 T cell cytokine differentiation: the B cell activation molecule, OX40 ligand, instructs CD4 T cells to express interleukin 4 and upregulates expression of the chemokine receptor, Blr-1. J Exp Med 1998;188:297-304.
-
(1998)
J Exp Med
, vol.188
, pp. 297-304
-
-
Flynn, S.1
Toellner, K.M.2
Raykundalia, C.3
Goodall, M.4
Lane, P.5
-
174
-
-
0035808782
-
Development of allergic inflammation in a murine model of asthma is dependent on the costimulatory receptor OX40
-
Jember AG, Zuberi R, Liu FT, Croft M. Development of allergic inflammation in a murine model of asthma is dependent on the costimulatory receptor OX40. J Exp Med 2001;193:387-392.
-
(2001)
J Exp Med
, vol.193
, pp. 387-392
-
-
Jember, A.G.1
Zuberi, R.2
Liu, F.T.3
Croft, M.4
-
175
-
-
0034677124
-
Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis
-
Akiba H, et al. Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis. J Exp Med 2000;191:375-380.
-
(2000)
J Exp Med
, vol.191
, pp. 375-380
-
-
Akiba, H.1
-
176
-
-
0031595673
-
Involvement of OX40-OX40L interactions in the intestinal manifestations of the murine acute graft-versus-host disease
-
Stuber E, Von Freier A, Marinescu D, Folsch UR. Involvement of OX40-OX40L interactions in the intestinal manifestations of the murine acute graft-versus-host disease. Gastroenterology 1998;115:1205-1215.
-
(1998)
Gastroenterology
, vol.115
, pp. 1205-1215
-
-
Stuber, E.1
Von Freier, A.2
Marinescu, D.3
Folsch, U.R.4
-
177
-
-
0032923689
-
CD4 T cell traffic control: In vivo evidence that ligation of OX40 on CD4 T cells by OX40-ligand expressed on dendritic cells leads to the accumulation of CD4 T cells in B follicles
-
Brocker T, Gulbranson-Judge A, Flynn S, Riedinger M, Raykundalia C, Lane P. CD4 T cell traffic control: in vivo evidence that ligation of OX40 on CD4 T cells by OX40-ligand expressed on dendritic cells leads to the accumulation of CD4 T cells in B follicles. Eur J Immunol 1999;29:1610-1616.
-
(1999)
Eur J Immunol
, vol.29
, pp. 1610-1616
-
-
Brocker, T.1
Gulbranson-Judge, A.2
Flynn, S.3
Riedinger, M.4
Raykundalia, C.5
Lane, P.6
-
178
-
-
13344283418
-
Selective depletion of myelin-reactive T cells with the anti-OX-40 antibody ameliorates autoimmune encephalomyelitis
-
Weinberg AD, et al. Selective depletion of myelin-reactive T cells with the anti-OX-40 antibody ameliorates autoimmune encephalomyelitis. Nat Med 1996;2:183-189.
-
(1996)
Nat Med
, vol.2
, pp. 183-189
-
-
Weinberg, A.D.1
-
179
-
-
0033083303
-
Blocking OX-40/OX-40 ligand interaction in vitro and in vivo leads to decreased T cell function and amelioration of experimental allergic encephalomyelitis
-
Weinberg AD, Wegmann KW, Funatake C, Whitham RH. Blocking OX-40/OX-40 ligand interaction in vitro and in vivo leads to decreased T cell function and amelioration of experimental allergic encephalomyelitis. J Immunol 1999;162:1818-1826.
-
(1999)
J Immunol
, vol.162
, pp. 1818-1826
-
-
Weinberg, A.D.1
Wegmann, K.W.2
Funatake, C.3
Whitham, R.H.4
-
180
-
-
0032955192
-
Regulation of T cell activation in vitro and in vivo by targeting the OX40-OX40 ligand interaction: Amelioration of ongoing inflammatory bowel disease with an OX40-IgG fusion protein, but not with an OX40 ligand-IgG fusion protein
-
Higgins LM, McDonald SA, Whittle N, Crockett N, Shields JG, MacDonald TT. Regulation of T cell activation in vitro and in vivo by targeting the OX40-OX40 ligand interaction: amelioration of ongoing inflammatory bowel disease with an OX40-IgG fusion protein, but not with an OX40 ligand-IgG fusion protein. J Immunol 1999;162:486-493.
-
(1999)
J Immunol
, vol.162
, pp. 486-493
-
-
Higgins, L.M.1
McDonald, S.A.2
Whittle, N.3
Crockett, N.4
Shields, J.G.5
MacDonald, T.T.6
-
181
-
-
0035253725
-
Amelioration of experimental autoimmune encephalomyelitis with anti-OX40 ligand monoclonal antibody: A critical role for OX40 ligand in migration, but not development, of pathogenic T cells
-
Nohara C, et al. Amelioration of experimental autoimmune encephalomyelitis with anti-OX40 ligand monoclonal antibody: a critical role for OX40 ligand in migration, but not development, of pathogenic T cells. J Immunol 2001;166:2108-2115.
-
(2001)
J Immunol
, vol.166
, pp. 2108-2115
-
-
Nohara, C.1
-
182
-
-
0033564303
-
CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells
-
Akiba H, et al. CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. J Immunol 1999;162:7058-7066.
-
(1999)
J Immunol
, vol.162
, pp. 7058-7066
-
-
Akiba, H.1
-
183
-
-
0037443415
-
The role of the CD134-CD134 ligand costimulatory pathway in alloimmune responses in vivo
-
Yuan X, et al. The role of the CD134-CD134 ligand costimulatory pathway in alloimmune responses in vivo. J Immunol 2003;170:2949-2955.
-
(2003)
J Immunol
, vol.170
, pp. 2949-2955
-
-
Yuan, X.1
-
184
-
-
0037528710
-
Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients
-
Blazar BR, et al. Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients. Blood 2003;101:3741-3748.
-
(2003)
Blood
, vol.101
, pp. 3741-3748
-
-
Blazar, B.R.1
-
185
-
-
0027285735
-
Inducible T cell antigen 4-1BB. Analysis of expression and function
-
Pollok KE, et al. Inducible T cell antigen 4-1BB. Analysis of expression and function. J Immunol 1993;150:771-781.
-
(1993)
J Immunol
, vol.150
, pp. 771-781
-
-
Pollok, K.E.1
-
186
-
-
0029117913
-
Potential role of 4-1BB in T cell activation. Comparison with the costimulatory molecule CD28
-
Hurtado JC, Kim SH, Pollok KE, Lee ZH, Kwon BS. Potential role of 4-1BB in T cell activation. Comparison with the costimulatory molecule CD28. J Immunol 1995;155:3360-3367.
-
(1995)
J Immunol
, vol.155
, pp. 3360-3367
-
-
Hurtado, J.C.1
Kim, S.H.2
Pollok, K.E.3
Lee, Z.H.4
Kwon, B.S.5
-
187
-
-
0032535119
-
NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies
-
Melero I, Johnston JV, Shufford WW, Mittler RS, Chen L. NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies. Cell Immunol 1998;190:167-172.
-
(1998)
Cell Immunol
, vol.190
, pp. 167-172
-
-
Melero, I.1
Johnston, J.V.2
Shufford, W.W.3
Mittler, R.S.4
Chen, L.5
-
188
-
-
0031569279
-
Signals through 4-1BB are costimulatory to previously activated splenic T cells and inhibit activation-induced cell death
-
Hurtado JC, Kim YJ, Kwon BS. Signals through 4-1BB are costimulatory to previously activated splenic T cells and inhibit activation-induced cell death. J Immunol 1997;158:2600-2609.
-
(1997)
J Immunol
, vol.158
, pp. 2600-2609
-
-
Hurtado, J.C.1
Kim, Y.J.2
Kwon, B.S.3
-
189
-
-
0027365746
-
Molecular cloning of a ligand for the inducible T cell gene 4-1BB. A member of an emerging family of cytokines with homology to tumor necrosis factor
-
Goodwin RG, et al. Molecular cloning of a ligand for the inducible T cell gene 4-1BB. a member of an emerging family of cytokines with homology to tumor necrosis factor. Eur J Immunol 1993;23:2631-2641.
-
(1993)
Eur J Immunol
, vol.23
, pp. 2631-2641
-
-
Goodwin, R.G.1
-
191
-
-
0028009709
-
4-1BB T-cell antigen binds to mature B cells and macrophages, and costimulates anti-mu-primed splenic B cells
-
Pollok KE, Kim YJ, Hurtado J, Zhou Z, Kim KK, Kwon BS. 4-1BB T-cell antigen binds to mature B cells and macrophages, and costimulates anti-mu-primed splenic B cells. Eur J Immunol 1994;24:367-374.
-
(1994)
Eur J Immunol
, vol.24
, pp. 367-374
-
-
Pollok, K.E.1
Kim, Y.J.2
Hurtado, J.3
Zhou, Z.4
Kim, K.K.5
Kwon, B.S.6
-
192
-
-
0030845586
-
+ T cell
-
+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses. J Exp Med 1997;186:47-55.
-
(1997)
J Exp Med
, vol.186
, pp. 47-55
-
-
Shuford, W.W.1
-
193
-
-
0033137063
-
Cutting edge: 4-1BB is a bona fide CD8 T cell survival signal
-
Takahashi C, Mittler RS, Vella AT. Cutting edge: 4-1BB is a bona fide CD8 T cell survival signal. J Immunol 1999;162:5037-5040.
-
(1999)
J Immunol
, vol.162
, pp. 5037-5040
-
-
Takahashi, C.1
Mittler, R.S.2
Vella, A.T.3
-
194
-
-
0032754036
-
Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus
-
DeBenedette MA, et al. Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus. J Immunol 1999;163:4833-4841.
-
(1999)
J Immunol
, vol.163
, pp. 4833-4841
-
-
DeBenedette, M.A.1
-
195
-
-
0033982793
-
Co-stimulation of antigen-specific CD4 T cells by 4-1BB ligand
-
Gramaglia I, Cooper D, Miner KT, Kwon BS, Croft M. Co-stimulation of antigen-specific CD4 T cells by 4-1BB ligand. Eur J Immunol 2000;30:392-402.
-
(2000)
Eur J Immunol
, vol.30
, pp. 392-402
-
-
Gramaglia, I.1
Cooper, D.2
Miner, K.T.3
Kwon, B.S.4
Croft, M.5
-
196
-
-
0033571176
-
Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy
-
Mittler RS, Bailey TS, Klussman K, Trailsmith MD, Hoffmann MK. Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy. J Exp Med 1999;190:1535-1540.
-
(1999)
J Exp Med
, vol.190
, pp. 1535-1540
-
-
Mittler, R.S.1
Bailey, T.S.2
Klussman, K.3
Trailsmith, M.D.4
Hoffmann, M.K.5
-
197
-
-
0031881906
-
Human 4-1BB regulates CD28 costimulation to promote Th1 cell responses
-
Kim YJ, Kim SH, Mantel P, Kwon BS. Human 4-1BB regulates CD28 costimulation to promote Th1 cell responses. Eur J Immunol 1998;28:881-890.
-
(1998)
Eur J Immunol
, vol.28
, pp. 881-890
-
-
Kim, Y.J.1
Kim, S.H.2
Mantel, P.3
Kwon, B.S.4
-
198
-
-
0035423265
-
4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy
-
Cannons JL, et al. 4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy. J Immunol 2001;167:1313-1324.
-
(2001)
J Immunol
, vol.167
, pp. 1313-1324
-
-
Cannons, J.L.1
-
200
-
-
0028955074
-
Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP
-
DeBenedette MA, et al. Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP. J Exp Med 1995;181:985-992.
-
(1995)
J Exp Med
, vol.181
, pp. 985-992
-
-
DeBenedette, M.A.1
-
201
-
-
0034662209
-
Analysis of expression and function of the costimulatory molecule 4-1BB in alloimmune responses
-
Tan JT, et al. Analysis of expression and function of the costimulatory molecule 4-1BB in alloimmune responses. Transplantation 2000;70:175-183.
-
(2000)
Transplantation
, vol.70
, pp. 175-183
-
-
Tan, J.T.1
-
203
-
-
0035284861
-
Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients
-
Blazar BR, Kwon BS, Panoskaltsis-Mortari A, Kwak KB, Peschon JJ, Taylor PA. Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients. J Immunol 2001;166:3174-3183.
-
(2001)
J Immunol
, vol.166
, pp. 3174-3183
-
-
Blazar, B.R.1
Kwon, B.S.2
Panoskaltsis-Mortari, A.3
Kwak, K.B.4
Peschon, J.J.5
Taylor, P.A.6
-
204
-
-
18344415315
-
Tumor necrosis factor receptor family members in the immune system
-
Gravestein LA, Borst J. Tumor necrosis factor receptor family members in the immune system. Semin Immunol 1998;10:423-434.
-
(1998)
Semin Immunol
, vol.10
, pp. 423-434
-
-
Gravestein, L.A.1
Borst, J.2
-
205
-
-
18344401896
-
CD27-mediated activation of murine NK cells
-
Takeda K, et al. CD27-mediated activation of murine NK cells. J Immunol 2000;164:1741-1745.
-
(2000)
J Immunol
, vol.164
, pp. 1741-1745
-
-
Takeda, K.1
-
206
-
-
0031573077
-
Characterization of murine CD70, the ligand of the TNF receptor family member CD27
-
Tesselaar K, Gravestein LA, van Schijndel GM, Borst J, van Lier RA. Characterization of murine CD70, the ligand of the TNF receptor family member CD27. J Immunol 1997;159:4959-4965.
-
(1997)
J Immunol
, vol.159
, pp. 4959-4965
-
-
Tesselaar, K.1
Gravestein, L.A.2
Van Schijndel, G.M.3
Borst, J.4
Van Lier, R.A.5
-
207
-
-
0034329745
-
CD27 is required for generation and long-term maintenance of T cell immunity
-
Hendriks J, Gravestein LA, Tesselaar K, van Lier RAW, Schumacher TNM, Borst J. CD27 is required for generation and long-term maintenance of T cell immunity. Nat Immunol 2000;1:433-440.
-
(2000)
Nat Immunol
, vol.1
, pp. 433-440
-
-
Hendriks, J.1
Gravestein, L.A.2
Tesselaar, K.3
Van Lier, R.A.W.4
Schumacher, T.N.M.5
Borst, J.6
-
208
-
-
0032816840
-
Involvement of the CD27-CD70 costimulatory pathway in allogeneic T- Cell response to follicular lymphoma cells
-
Schmitter D, Bolliger U, Hallek M, Pichert G. Involvement of the CD27-CD70 costimulatory pathway in allogeneic T-cell response to follicular lymphoma cells. Br J Haematol 1999;106:64-70.
-
(1999)
Br J Haematol
, vol.106
, pp. 64-70
-
-
Schmitter, D.1
Bolliger, U.2
Hallek, M.3
Pichert, G.4
-
209
-
-
7144235808
-
Characterization of murine CD70 by molecular cloning and mAb
-
Oshima H, et al. Characterization of murine CD70 by molecular cloning and mAb. Int Immunol 1998;10:517-526.
-
(1998)
Int Immunol
, vol.10
, pp. 517-526
-
-
Oshima, H.1
-
210
-
-
0034100170
-
CD27/CD70 interactions regulate T dependent B cell differentiation
-
Jacquot S. CD27/CD70 interactions regulate T dependent B cell differentiation. Immunol Res 2000;21:23-30.
-
(2000)
Immunol Res
, vol.21
, pp. 23-30
-
-
Jacquot, S.1
-
211
-
-
0034703189
-
Involvement of CD70-CD27 interactions in the induction of experimental autoimmune encephalomyelitis
-
Nakajima A, et al. Involvement of CD70-CD27 interactions in the induction of experimental autoimmune encephalomyelitis. J Neuroimmunol 2000;109:188-196.
-
(2000)
J Neuroimmunol
, vol.109
, pp. 188-196
-
-
Nakajima, A.1
|