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Volumn 18, Issue 3, 2016, Pages 350-361

Sensitivity Analysis of the MGMT-STP27 Model and Impact of Genetic and Epigenetic Context to Predict the MGMT Methylation Status in Gliomas and Other Tumors

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN; STP27 PROTEIN; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; DNA LIGASE; DNA METHYLTRANSFERASE; MGMT PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

EID: 84963977862     PISSN: 15251578     EISSN: 19437811     Source Type: Journal    
DOI: 10.1016/j.jmoldx.2015.11.009     Document Type: Article
Times cited : (86)

References (59)
  • 1
    • 84867606428 scopus 로고    scopus 로고
    • Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma
    • D. Sturm, H. Witt, V. Hovestadt, D.A. Khuong-Quang, D.T. Jones, C. Konermann, and et al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma Cancer Cell 22 2012 425 437
    • (2012) Cancer Cell , vol.22 , pp. 425-437
    • Sturm, D.1    Witt, H.2    Hovestadt, V.3    Khuong-Quang, D.A.4    Jones, D.T.5    Konermann, C.6
  • 4
    • 84865558322 scopus 로고    scopus 로고
    • Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: The Nordic randomised, phase 3 trial
    • A. Malmstrom, B.H. Gronberg, C. Marosi, R. Stupp, D. Frappaz, H. Schultz, U. Abacioglu, B. Tavelin, B. Lhermitte, M.E. Hegi, J. Rosell, R. Henriksson Nordic Clinical Brain Tumor Study Group (NCBTSG) Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial Lancet Oncol 13 2012 916 926
    • (2012) Lancet Oncol , vol.13 , pp. 916-926
    • Malmstrom, A.1    Gronberg, B.H.2    Marosi, C.3    Stupp, R.4    Frappaz, D.5    Schultz, H.6    Abacioglu, U.7    Tavelin, B.8    Lhermitte, B.9    Hegi, M.E.10    Rosell, J.11    Henriksson, R.12
  • 6
    • 84868019401 scopus 로고    scopus 로고
    • Personalized care in neuro-oncology coming of age: Why we need MGMT and 1p/19q testing for malignant glioma patients in clinical practice
    • M. Weller, R. Stupp, M.E. Hegi, M. van den Bent, J.C. Tonn, M. Sanson, W. Wick, and G. Reifenberger Personalized care in neuro-oncology coming of age: why we need MGMT and 1p/19q testing for malignant glioma patients in clinical practice Neuro Oncol 14 Suppl 4 2012 iv100 iv108
    • (2012) Neuro Oncol , vol.14 , pp. iv100-iv108
    • Weller, M.1    Stupp, R.2    Hegi, M.E.3    Van Den Bent, M.4    Tonn, J.C.5    Sanson, M.6    Wick, W.7    Reifenberger, G.8
  • 11
    • 84866542816 scopus 로고    scopus 로고
    • MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status
    • P. Bady, D. Sciuscio, A.C. Diserens, J. Bloch, M.J. van den Bent, C. Marosi, P.Y. Dietrich, M. Weller, L. Mariani, F.L. Heppner, D.R. McDonald, D. Lacombe, R. Stupp, M. Delorenzi, and M.E. Hegi MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status Acta Neuropathol 124 2012 547 560
    • (2012) Acta Neuropathol , vol.124 , pp. 547-560
    • Bady, P.1    Sciuscio, D.2    Diserens, A.C.3    Bloch, J.4    Van Den Bent, M.J.5    Marosi, C.6    Dietrich, P.Y.7    Weller, M.8    Mariani, L.9    Heppner, F.L.10    McDonald, D.R.11    Lacombe, D.12    Stupp, R.13    Delorenzi, M.14    Hegi, M.E.15
  • 16
    • 84862173149 scopus 로고    scopus 로고
    • SWAN: Subset-quantile within array normalization for illumina infinium HumanMethylation450 BeadChips
    • J. Maksimovic, L. Gordon, and A. Oshlack SWAN: subset-quantile within array normalization for illumina infinium HumanMethylation450 BeadChips Genome Biol 13 2012 R44
    • (2012) Genome Biol , vol.13 , pp. R44
    • Maksimovic, J.1    Gordon, L.2    Oshlack, A.3
  • 23
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • Cancer Genome Atlas Research Network Comprehensive genomic characterization defines human glioblastoma genes and core pathways Nature 455 2008 1061 1068
    • (2008) Nature , vol.455 , pp. 1061-1068
  • 24
    • 84932628860 scopus 로고    scopus 로고
    • Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas
    • Cancer Genome Atlas Research Network D.J. Brat, R.G. Verhaak, K.D. Aldape, W.K. Yung, S.R. Salama, L.A. Cooper, and et al. Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas N Engl J Med 372 2015 2481 2498
    • (2015) N Engl J Med , vol.372 , pp. 2481-2498
    • Brat, D.J.1    Verhaak, R.G.2    Aldape, K.D.3    Yung, W.K.4    Salama, S.R.5    Cooper, L.A.6
  • 25
    • 78649475003 scopus 로고    scopus 로고
    • Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
    • P. Du, X. Zhang, C.C. Huang, N. Jafari, W.A. Kibbe, L. Hou, and S.M. Lin Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis BMC Bioinformatics 11 2010 587
    • (2010) BMC Bioinformatics , vol.11 , pp. 587
    • Du, P.1    Zhang, X.2    Huang, C.C.3    Jafari, N.4    Kibbe, W.A.5    Hou, L.6    Lin, S.M.7
  • 30
    • 3543105225 scopus 로고    scopus 로고
    • Circular binary segmentation for the analysis of array-based DNA copy number data
    • A.B. Olshen, E.S. Venkatraman, R. Lucito, and M. Wigler Circular binary segmentation for the analysis of array-based DNA copy number data Biostatistics 5 2004 557 572
    • (2004) Biostatistics , vol.5 , pp. 557-572
    • Olshen, A.B.1    Venkatraman, E.S.2    Lucito, R.3    Wigler, M.4
  • 31
    • 0001876747 scopus 로고
    • Algorithm AS159. An efficient method of generating r x c tables with given row and column totals
    • W.M. Patefield Algorithm AS159. An efficient method of generating r x c tables with given row and column totals Appl Stat 30 1981 91 97
    • (1981) Appl Stat , vol.30 , pp. 91-97
    • Patefield, W.M.1
  • 33
    • 77949568386 scopus 로고    scopus 로고
    • An exact permutation method for testing any effect in balanced and unbalanced fixed effect ANOVA
    • S. Kherad-Pajouh, and O. Renaud An exact permutation method for testing any effect in balanced and unbalanced fixed effect ANOVA Comput Stat Data Anal 54 2010 1881 1893
    • (2010) Comput Stat Data Anal , vol.54 , pp. 1881-1893
    • Kherad-Pajouh, S.1    Renaud, O.2
  • 34
    • 0032874498 scopus 로고    scopus 로고
    • Interpreting validity indexes for diagnostic tests: An illustration using the Berg balance test
    • D.L. Riddle, and P.W. Stratford Interpreting validity indexes for diagnostic tests: an illustration using the Berg balance test Phys Ther 79 1999 939 948
    • (1999) Phys Ther , vol.79 , pp. 939-948
    • Riddle, D.L.1    Stratford, P.W.2
  • 35
    • 59849104111 scopus 로고    scopus 로고
    • Use of the noninvasive components of the Mayo score to assess clinical response in ulcerative colitis
    • J.D. Lewis, S. Chuai, L. Nessel, G.R. Lichtenstein, F.N. Aberra, and J.H. Ellenberg Use of the noninvasive components of the Mayo score to assess clinical response in ulcerative colitis Inflamm Bowel Dis 14 2008 1660 1666
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 1660-1666
    • Lewis, J.D.1    Chuai, S.2    Nessel, L.3    Lichtenstein, G.R.4    Aberra, F.N.5    Ellenberg, J.H.6
  • 37
    • 16244366026 scopus 로고
    • Index for rating diagnostic tests
    • W.J. Youden Index for rating diagnostic tests Cancer 3 1950 32 35
    • (1950) Cancer , vol.3 , pp. 32-35
    • Youden, W.J.1
  • 38
    • 0016729922 scopus 로고
    • The accuracy of diver sound localization by pointing
    • S.H. Feinstein The accuracy of diver sound localization by pointing Undersea Biomed Res 2 1975 173 184
    • (1975) Undersea Biomed Res , vol.2 , pp. 173-184
    • Feinstein, S.H.1
  • 39
    • 84973587732 scopus 로고
    • A Coefficient of agreement for nominal scales
    • J. Cohen A Coefficient of agreement for nominal scales Educ Psychol Meas 20 1960 37 46
    • (1960) Educ Psychol Meas , vol.20 , pp. 37-46
    • Cohen, J.1
  • 41
    • 0942279488 scopus 로고    scopus 로고
    • Generating mutations but providing chemosensitivity: The role of O6-methylguanine DNA methyltransferase in human cancer
    • M. Esteller, and J.G. Herman Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer Oncogene 23 2004 1 8
    • (2004) Oncogene , vol.23 , pp. 1-8
    • Esteller, M.1    Herman, J.G.2
  • 46
    • 19244370208 scopus 로고    scopus 로고
    • Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis
    • M. Esteller, M. Toyota, M. Sanchez-Cespedes, G. Capella, M.A. Peinado, D.N. Watkins, J.P. Issa, D. Sidransky, S.B. Baylin, and J.G. Herman Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis Cancer Res 60 2000 2368 2371
    • (2000) Cancer Res , vol.60 , pp. 2368-2371
    • Esteller, M.1    Toyota, M.2    Sanchez-Cespedes, M.3    Capella, G.4    Peinado, M.A.5    Watkins, D.N.6    Issa, J.P.7    Sidransky, D.8    Baylin, S.B.9    Herman, J.G.10
  • 47
    • 80052829123 scopus 로고    scopus 로고
    • Promoter methylation status of hMLH1, hMSH2, and MGMT genes in colorectal cancer associated with adenoma-carcinoma sequence
    • K.H. Lee, J.S. Lee, J.H. Nam, C. Choi, M.C. Lee, C.S. Park, S.W. Juhng, and J.H. Lee Promoter methylation status of hMLH1, hMSH2, and MGMT genes in colorectal cancer associated with adenoma-carcinoma sequence Langenbecks Arch Surg 396 2011 1017 1026
    • (2011) Langenbecks Arch Surg , vol.396 , pp. 1017-1026
    • Lee, K.H.1    Lee, J.S.2    Nam, J.H.3    Choi, C.4    Lee, M.C.5    Park, C.S.6    Juhng, S.W.7    Lee, J.H.8
  • 49
    • 77954954112 scopus 로고    scopus 로고
    • Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas
    • J. Kim, J. Choi, S. Roh, D. Cho, T. Kim, and Y. Kim Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas Ann Surg Oncol 17 2010 1767 1776
    • (2010) Ann Surg Oncol , vol.17 , pp. 1767-1776
    • Kim, J.1    Choi, J.2    Roh, S.3    Cho, D.4    Kim, T.5    Kim, Y.6
  • 51
    • 34247129670 scopus 로고    scopus 로고
    • Comethylation of p16 and MGMT genes in colorectal carcinoma: Correlation with clinicopathological features and prognostic value
    • K. Krtolica, M. Krajnovic, S. Usaj-Knezevic, D. Babic, D. Jovanovic, and B. Dimitrijevic Comethylation of p16 and MGMT genes in colorectal carcinoma: correlation with clinicopathological features and prognostic value World J Gastroenterol 13 2007 1187 1194
    • (2007) World J Gastroenterol , vol.13 , pp. 1187-1194
    • Krtolica, K.1    Krajnovic, M.2    Usaj-Knezevic, S.3    Babic, D.4    Jovanovic, D.5    Dimitrijevic, B.6
  • 57
    • 67649197934 scopus 로고    scopus 로고
    • Ratio adjustment and calibration scheme for gene-wise normalization to enhance microarray inter-study prediction
    • C. Cheng, K. Shen, C. Song, J. Luo, and G.C. Tseng Ratio adjustment and calibration scheme for gene-wise normalization to enhance microarray inter-study prediction Bioinformatics 25 2009 1655 1661
    • (2009) Bioinformatics , vol.25 , pp. 1655-1661
    • Cheng, C.1    Shen, K.2    Song, C.3    Luo, J.4    Tseng, G.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.