Promoter methylation status of hMLH1, hMSH2, and MGMT genes in colorectal cancer associated with adenoma-carcinoma sequence

Langenbeck's Archives of Surgery

Volumn 396, Issue 7, 2011, Pages 1017-1026

  Lee, Kyung Hwa ^a   Lee, Ji Shin ^a   Nam, Jong Hee ^a   Choi, Chan ^a   Lee, Min Cheol ^a   Park, Chang Soo ^a   Juhng, Sang Woo ^a   Lee, Jae Hyuk ^a  

^a Chonnam National University   (South Korea)

Author keywords

Colorectal carcinoma; DNA mismatch repair; hMLH; hMSH2; Methylation; MGMT

Indexed keywords

BISULFITE; DNA;

ADULT; AGED; ARTICLE; CARCINOGENESIS; COLORECTAL ADENOMA; COLORECTAL CANCER; CONTROLLED STUDY; DNA METHYLATION; DNA MODIFICATION; FEMALE; GENE EXPRESSION PROFILING; GENE LOSS; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC CORRELATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE MUCOSA; MAJOR CLINICAL STUDY; MALE; MUTL HOMOLOG 1 GENE; MUTS HOMOLOG 2 GENE; O 6 METHYLGUANINE DNA METHYLTRANSFERASE GENE; PRIORITY JOURNAL; PROMOTER REGION; TUMOR GENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA; COHORT STUDIES; COLORECTAL NEOPLASMS; CONFIDENCE INTERVALS; DATABASES, FACTUAL; DNA METHYLATION; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; ODDS RATIO; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, DNA; TUMOR SUPPRESSOR PROTEINS;

EID: 80052829123     PISSN: 14352443     EISSN: 14352451     Source Type: Journal    
DOI: 10.1007/s00423-011-0812-9     Document Type: Article

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