Chromosome 7 gain and DNA hypermethylation at the HOXA10 locus are associated with expression of a stem cell related HOX-signature in glioblastoma

Genome Biology

Volumn 16, Issue 1, 2015, Pages

  Kurscheid, Sebastian ^a,b,m   Bady, Pierre ^a,b,c   Sciuscio, Davide ^a   Samarzija, Ivana ^a   Shay, Tal ^d   Vassallo, Irene ^a   Criekinge, Wim V ^e   Daniel, Roy T ^a   van den Bent, Martin J ^f   Marosi, Christine ^g   Weller, Michael ^h,i   Mason, Warren P ^j   Domany, Eytan ^k   Stupp, Roger ^a,l   Delorenzi, Mauro ^b,c   Hegi, Monika E ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

^d BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^e GHENT UNIVERSITY   (Belgium)

^f ERASMUS MC CANCER INSTITUTE   (Netherlands)

^g MEDICAL UNIVERSITY OF VIENNA   (Austria)

^h UNIVERSITY OF TÜBINGEN   (Germany)

ⁱ UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^j UNIVERSITY OF TORONTO   (Canada)

^k WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^l UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^m Australian National University   (Australia)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HISTONE; MICRORNA; RNA; TRANSCRIPTION FACTOR HOXA10; HOMEODOMAIN PROTEIN; HOXA10 PROTEIN, HUMAN; TRANSCRIPTOME;

ARTICLE; CANCER TISSUE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME 7; CPG ISLAND; DNA METHYLATION; GENE DOSAGE; GENE EXPRESSION; GENE LOCUS; GLIOBLASTOMA; HOXA10 GENE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PROMOTER REGION; RNA SEQUENCE; BRAIN; CANCER STEM CELL; COPY NUMBER VARIATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC DATABASE; GENETIC EPIGENESIS; GENETICS; HUMAN GENOME; METABOLISM; MULTICELLULAR SPHEROID; PATHOLOGY; STATISTICAL MODEL; TUMOR CELL LINE;

BRAIN; CELL LINE, TUMOR; CHROMOSOMES, HUMAN, PAIR 7; CPG ISLANDS; DATABASES, GENETIC; DNA COPY NUMBER VARIATIONS; DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC LOCI; GENOME, HUMAN; GLIOBLASTOMA; HISTONES; HOMEODOMAIN PROTEINS; HUMANS; LINEAR MODELS; MICRORNAS; NEOPLASTIC STEM CELLS; PROMOTER REGIONS, GENETIC; SPHEROIDS, CELLULAR; TRANSCRIPTOME;

EID: 84924286644     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-015-0583-7     Document Type: Article

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