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Volumn 9, Issue 14, 2003, Pages 5306-5312

Hypermethylation of O6-Methylguanine-DNA Methyltransferase Promoter May Predict Nonrecurrence after Chemotherapy in Colorectal Cancer Cases

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE;

EID: 0242610375     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (83)

References (24)
  • 1
    • 0025195404 scopus 로고
    • 6-alkylguanine-DNA alkyltransferase: Regulation and importance in response to alkylating carcinogenic and therapeutic agents
    • 6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents. Cancer Res., 50: 6119-6129, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 6119-6129
    • Pegg, A.E.1
  • 3
    • 0017606476 scopus 로고
    • Genetic studies of the lac repressor. III. Additional correlation of mutational sites with specific amino acid residues
    • Coulondre, C., and Miller, J. H. Genetic studies of the lac repressor. III. Additional correlation of mutational sites with specific amino acid residues. J. Mol. Biol., 117: 525-567, 1977.
    • (1977) J. Mol. Biol. , vol.117 , pp. 525-567
    • Coulondre, C.1    Miller, J.H.2
  • 4
    • 0032851842 scopus 로고    scopus 로고
    • Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents
    • Hickman, M. J., and Samson, L. D. Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents. Proc. Natl. Acad. Sci. USA, 96: 10764-10769, 1999.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10764-10769
    • Hickman, M.J.1    Samson, L.D.2
  • 9
    • 0029935385 scopus 로고    scopus 로고
    • 6-alkylguanine-DNA alkyltransferase expression in human brain tumors: Possible significance in nitrosourea therapy
    • 6-alkylguanine-DNA alkyltransferase expression in human brain tumors: possible significance in nitrosourea therapy. Carcinogenesis (Lond.), 17: 637-641, 1996.
    • (1996) Carcinogenesis (Lond.) , vol.17 , pp. 637-641
    • Lee, S.M.1    Reid, H.2    Elder, R.H.3    Thatcher, N.4    Margison, G.P.5
  • 11
    • 0029162051 scopus 로고
    • 6-methylguanine-DNA methyltransferase in human Mer+ and Mer- cells
    • 6-methylguanine-DNA methyltransferase in human Mer+ and Mer- cells. Carcinogenesis (Lond.), 16: 1857-1863, 1995.
    • (1995) Carcinogenesis (Lond.) , vol.16 , pp. 1857-1863
    • Skorpen, F.1    Krokan, H.E.2
  • 12
    • 0035117307 scopus 로고    scopus 로고
    • 6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability
    • 6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability. Cancer Res., 61: 827-830, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 827-830
    • Whitehall, V.L.1    Walsh, M.D.2    Young, J.3    Leggett, B.A.4    Jass, J.R.5
  • 13
    • 0033557903 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
    • 6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res., 59: 793-797, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 793-797
    • Esteller, M.1    Hamilton, S.R.2    Burger, P.C.3    Baylin, S.B.4    Herman, J.G.5
  • 15
    • 0035575781 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase gene is associated significantly with K-ras mutation, lymph node invasion, tumor staging, and disease free survival in patients with gastric carcinoma
    • 6-methylguanine-DNA methyltransferase gene is associated significantly with K-ras mutation, lymph node invasion, tumor staging, and disease free survival in patients with gastric carcinoma. Cancer (Phila.), 92: 2760-2768, 2001.
    • (2001) Cancer (Phila.) , vol.92 , pp. 2760-2768
    • Park, T.J.1    Han, S.U.2    Cho, Y.K.3    Paik, W.K.4    Kim, Y.B.5    Lim, I.K.6
  • 18
    • 0032969319 scopus 로고    scopus 로고
    • A specific CpG methylation pattern of the MGMT promoter region associated with reduced MGMT expression in primary colorectal cancers
    • Herfarth, K. K., Brent, T. P., Danam, R. P., Remack, J. S., Kodner, I. J., Wells, S. A., Jr., and Goodfellow, P. J. A specific CpG methylation pattern of the MGMT promoter region associated with reduced MGMT expression in primary colorectal cancers. Mol. Carcinog., 24: 90-98, 1999.
    • (1999) Mol. Carcinog. , vol.24 , pp. 90-98
    • Herfarth, K.K.1    Brent, T.P.2    Danam, R.P.3    Remack, J.S.4    Kodner, I.J.5    Wells Jr., S.A.6    Goodfellow, P.J.7
  • 19
    • 0025268278 scopus 로고
    • Exposure of humans to endogenous N-nitroso compounds: Implications in cancer etiology
    • Bartsch, H., Ohshima, H., Shuker, D. E., Pignatelli, B., and Calmels, S. Exposure of humans to endogenous N-nitroso compounds: implications in cancer etiology. Mutat. Res., 238: 255-267, 1990.
    • (1990) Mutat. Res. , vol.238 , pp. 255-267
    • Bartsch, H.1    Ohshima, H.2    Shuker, D.E.3    Pignatelli, B.4    Calmels, S.5
  • 20
    • 0025778705 scopus 로고
    • Endogenous N-nitrosation in man assessed by measurement of apparent total N-nitroso compounds in faeces
    • Rowland, I. R., Granli, T., Bockman, O. C., Key, P. E., and Massey, R. C. Endogenous N-nitrosation in man assessed by measurement of apparent total N-nitroso compounds in faeces. Carcinogenesis (Lond.), 12: 1395-1401, 1991.
    • (1991) Carcinogenesis (Lond.) , vol.12 , pp. 1395-1401
    • Rowland, I.R.1    Granli, T.2    Bockman, O.C.3    Key, P.E.4    Massey, R.C.5
  • 21
    • 0024442373 scopus 로고
    • Influence of dietary protein and gut microflora on endogenous synthesis of nitrate and N-nitrosamines in the rat
    • Ward, F. W., Coates, M. E., and Walker, R. Influence of dietary protein and gut microflora on endogenous synthesis of nitrate and N-nitrosamines in the rat. Food Chem. Toxicol., 27: 445-449, 1989.
    • (1989) Food Chem. Toxicol. , vol.27 , pp. 445-449
    • Ward, F.W.1    Coates, M.E.2    Walker, R.3
  • 23
    • 0025743158 scopus 로고
    • The detection of alkylation damage in the DNA of human gastrointestinal tissues
    • Hall, C. N., Badawi, A. F., O'Connor, P. J., and Saffhill, R. The detection of alkylation damage in the DNA of human gastrointestinal tissues. Br. J. Cancer. 64: 59-63, 1991.
    • (1991) Br. J. Cancer , vol.64 , pp. 59-63
    • Hall, C.N.1    Badawi, A.F.2    O'Connor, P.J.3    Saffhill, R.4
  • 24
    • 0032587342 scopus 로고    scopus 로고
    • 6-benzylguanine on the antitumour activity and normal tissue toxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea and molecular combinations of 5-fluorouracil and 2-chloro-ethyl-1-nitrosourea in mice
    • 6-benzylguanine on the antitumour activity and normal tissue toxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea and molecular combinations of 5-fluorouracil and 2-chloro-ethyl-1-nitrosourea in mice. Br. J. Cancer, 79: 1332-1339, 1999.
    • (1999) Br. J. Cancer , vol.79 , pp. 1332-1339
    • Bibby, M.C.1    Thompson, M.J.2    Rafferty, J.A.3    Margison, G.P.4    McElhinney, R.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.