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Volumn 6, Issue , 2016, Pages

Hepatitis B virus X protein (HBx)-induced abnormalities of nucleic acid metabolism revealed by 1 H-NMR-based metabonomics

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B VIRUS X PROTEIN; NUCLEIC ACID; TRANSACTIVATOR PROTEIN;

EID: 84963830615     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep24430     Document Type: Article
Times cited : (45)

References (43)
  • 1
    • 84938529503 scopus 로고    scopus 로고
    • Proteomic and metabonomic biomarkers for hepatocellular carcinoma: A comprehensive review
    • Kimhofer, T., Fye, H., Taylor-Robinson, S., Thursz, M. & Holmes, E. Proteomic and metabonomic biomarkers for hepatocellular carcinoma: a comprehensive review. Br J Cancer 112, 1141-1156, doi: 10.1038/bjc.2015.38 (2015).
    • (2015) Br J Cancer , vol.112 , pp. 1141-1156
    • Kimhofer, T.1    Fye, H.2    Taylor-Robinson, S.3    Thursz, M.4    Holmes, E.5
  • 2
    • 77949683758 scopus 로고    scopus 로고
    • Hepatitis b virus infection in dentistry: A forgotten topic
    • Mahboobi, N. et al. Hepatitis B virus infection in dentistry: a forgotten topic. J Viral Hepat 17, 307-316, doi: 10.1111/j.1365-2893.2010.01284.x (2010).
    • (2010) J Viral Hepat , vol.17 , pp. 307-316
    • Mahboobi, N.1
  • 3
    • 80055046798 scopus 로고    scopus 로고
    • Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans
    • Yang, F. et al. Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans. Hepatology 54, 1679-1689, doi: 10.1002/hep.24563 (2011).
    • (2011) Hepatology , vol.54 , pp. 1679-1689
    • Yang, F.1
  • 4
    • 84937512244 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocyte activity is enhanced in tumors with low il-10 production in hbv-induced hepatocellular carcinoma
    • Shi, Y., Song, Q., Hu, D., Zhuang, X. & Yu, S. Tumor-infiltrating lymphocyte activity is enhanced in tumors with low IL-10 production in HBV-induced hepatocellular carcinoma. Biochem Biophys Res Commun 461, 109-114, doi: 10.1016/j.bbrc.2015.03.177 (2015).
    • (2015) Biochem Biophys Res Commun , vol.461 , pp. 109-114
    • Shi, Y.1    Song, Q.2    Hu, D.3    Zhuang, X.4    Yu, S.5
  • 5
    • 34547171180 scopus 로고    scopus 로고
    • Metabonomic studies of human hepatocellular carcinoma using high-resolution magic-Angle spinning h-1 nmr spectroscopy in conjunction with multivariate data analysis
    • Yang, Y. X. et al. Metabonomic studies of human hepatocellular carcinoma using high-resolution magic-Angle spinning H-1 NMR spectroscopy in conjunction with multivariate data analysis. Journal of Proteome Research 6, 2605-2614, doi: 10.1021/pr070063h (2007).
    • (2007) Journal of Proteome Research , vol.6 , pp. 2605-2614
    • Yang, Y.X.1
  • 6
    • 84868122238 scopus 로고    scopus 로고
    • Comprehensive analysis of common serum liver enzymes as prospective predictors of hepatocellular carcinoma in hbv patients
    • Hann, H. W. et al. Comprehensive analysis of common serum liver enzymes as prospective predictors of hepatocellular carcinoma in HBV patients. PLoS One 7, e47687, doi: 10.1371/journal.pone.0047687 (2012).
    • (2012) PLoS One , vol.7 , pp. e47687
    • Hann, H.W.1
  • 7
    • 84984548158 scopus 로고    scopus 로고
    • Impact of hepatitis b virus infection on metabolic profiles and modifying factors
    • Hsu, C. S. et al. Impact of hepatitis B virus infection on metabolic profiles and modifying factors. J Viral Hepat 19, e48-57, doi: 10.1111/j.1365-2893.2011.01535.x (2012).
    • (2012) J Viral Hepat , vol.19 , pp. e48-57
    • Hsu, C.S.1
  • 8
    • 84939951763 scopus 로고    scopus 로고
    • Adipocytokines and liver fibrosis stages in patients with chronic hepatitis b virus infection
    • Hsu, C. S. et al. Adipocytokines and liver fibrosis stages in patients with chronic hepatitis B virus infection. Hepatol Int 9, 231-242, doi: 10.1007/s12072-015-9616-2 (2015).
    • (2015) Hepatol Int , vol.9 , pp. 231-242
    • Hsu, C.S.1
  • 9
    • 70349321699 scopus 로고    scopus 로고
    • A metabonomic study of hepatitis b-induced liver cirrhosis and hepatocellular carcinoma by using rp-lc and hilic coupled with mass spectrometry
    • Yin, P. et al. A metabonomic study of hepatitis B-induced liver cirrhosis and hepatocellular carcinoma by using RP-LC and HILIC coupled with mass spectrometry. Mol Biosyst 5, 868-876, doi: 10.1039/b820224a (2009).
    • (2009) Mol Biosyst , vol.5 , pp. 868-876
    • Yin, P.1
  • 10
    • 67449085093 scopus 로고    scopus 로고
    • Application of1h nmr-based metabonomics in the study of metabolic profiling of human hepatocellular carcinoma and liver cirrhosis
    • Gao, H. et al. Application of1H NMR-based metabonomics in the study of metabolic profiling of human hepatocellular carcinoma and liver cirrhosis. Cancer Science 100, 782-785, doi: 10.1111/j.1349-7006.2009.01086.x (2009).
    • (2009) Cancer Science , vol.100 , pp. 782-785
    • Gao, H.1
  • 11
    • 84922261384 scopus 로고    scopus 로고
    • Binding of hepatitis b virus to its cellular receptor alters the expression profile of genes of bile acid metabolism
    • Oehler, N. et al. Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism. Hepatology 60, 1483-1493, doi: 10.1002/hep.27159 (2014).
    • (2014) Hepatology , vol.60 , pp. 1483-1493
    • Oehler, N.1
  • 12
    • 84929211544 scopus 로고    scopus 로고
    • Hepatitis b virus x protein induces expression of alpha-fetoprotein and activates pi3k/mtor signaling pathway in liver cells
    • Zhu, M. et al. Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells. Oncotarget 6, 12196-12208, doi: 10.18632/oncotarget.2906 (2015).
    • (2015) Oncotarget , vol.6 , pp. 12196-12208
    • Zhu, M.1
  • 13
    • 65449149413 scopus 로고    scopus 로고
    • Liver x receptor mediates hepatitis b virus x protein-induced lipogenesis in hepatitis b virus-Associated hepatocellular carcinoma
    • Na, T. Y. et al. Liver X receptor mediates hepatitis B virus X protein-induced lipogenesis in hepatitis B virus-Associated hepatocellular carcinoma. Hepatology 49, 1122-1131, doi: 10.1002/hep.22740 (2009).
    • (2009) Hepatology , vol.49 , pp. 1122-1131
    • Na, T.Y.1
  • 14
    • 84924942637 scopus 로고    scopus 로고
    • Study of the cardiotoxicity of venenum bufonis in rats using an 1h nmr-based metabolomics approach
    • Dong, G. et al. Study of the cardiotoxicity of Venenum Bufonis in rats using an 1H NMR-based metabolomics approach. PLoS One 10, e0119515, doi: 10.1371/journal.pone.0119515 (2015).
    • (2015) PLoS One , vol.10 , pp. e0119515
    • Dong, G.1
  • 15
    • 84922627331 scopus 로고    scopus 로고
    • Plasma metabolite biomarkers for the detection of pancreatic cancer
    • Xie, G. et al. Plasma metabolite biomarkers for the detection of pancreatic cancer. J Proteome Res 14, 1195-1202, doi: 10.1021/pr501135f (2015).
    • (2015) J Proteome Res , vol.14 , pp. 1195-1202
    • Xie, G.1
  • 16
    • 84958972772 scopus 로고    scopus 로고
    • 1h nuclear magnetic resonance (nmr) metabolomic study of chronic organophosphate exposure in rats
    • Alam, T. M. et al. 1H Nuclear Magnetic Resonance (NMR) Metabolomic Study of Chronic Organophosphate Exposure in Rats. Metabolites 2, 479-495, doi: 10.3390/metabo2030479 (2012).
    • (2012) Metabolites , vol.2 , pp. 479-495
    • Alam, T.M.1
  • 17
    • 84938770401 scopus 로고    scopus 로고
    • Functional dissection of proliferating-cell nuclear antigens 1 and 2) in human malarial parasite plasmodium falciparum: Possible involvement in DNA replication and DNA damage response
    • Mitra, P., Banu, K., Deshmukh, A. S., Subbarao, N. & Dhar, S. K. Functional dissection of proliferating-cell nuclear antigens (1 and 2) in human malarial parasite Plasmodium falciparum: possible involvement in DNA replication and DNA damage response. Biochem J 470, 115-129, doi: 10.1042/BJ20150452 (2015).
    • (2015) Biochem J , vol.470 , pp. 115-129
    • Mitra, P.1    Banu, K.2    Deshmukh, A.S.3    Subbarao, N.4    Dhar, S.K.5
  • 18
    • 84937460080 scopus 로고    scopus 로고
    • Cdc42 gtpase activation affects hela cell DNA repair and proliferation following uv radiation-induced genotoxic stress
    • Ascer, L. G. et al. CDC42 Gtpase Activation Affects Hela Cell DNA Repair and Proliferation Following UV Radiation-Induced Genotoxic Stress. J Cell Biochem 116, 2086-2097, doi: 10.1002/jcb.25166 (2015).
    • (2015) J Cell Biochem , vol.116 , pp. 2086-2097
    • Ascer, L.G.1
  • 19
    • 84881243042 scopus 로고    scopus 로고
    • H2ax as a marker of DNA double strand breaks and genomic instability in human population studies
    • Valdiglesias, V., Giunta, S., Fenech, M., Neri, M. & Bonassi, S. H2AX as a marker of DNA double strand breaks and genomic instability in human population studies. Mutation Research/Reviews in Mutation Research 753, 24-40, doi: 10.1016/j.mrrev.2013. 02.001 (2013).
    • (2013) Mutation Research/Reviews in Mutation Research , vol.753 , pp. 24-40
    • Valdiglesias, V.1    Giunta, S.2    Fenech, M.3    Neri, M.4    Bonassi, S.5
  • 20
    • 77952116482 scopus 로고    scopus 로고
    • H2ax phosphorylation screen of cells from radiosensitive cancer patients reveals a novel DNA double-strand break repair cellular phenotype
    • Vasireddy, R. S., Sprung, C. N., Cempaka, N. L., Chao, M. & McKay, M. J. H2AX phosphorylation screen of cells from radiosensitive cancer patients reveals a novel DNA double-strand break repair cellular phenotype. Br J Cancer 102, 1511-1518, doi: 10.1038/sj. bjc.6605666 (2010).
    • (2010) Br J Cancer , vol.102 , pp. 1511-1518
    • Vasireddy, R.S.1    Sprung, C.N.2    Cempaka, N.L.3    Chao, M.4    McKay, M.J.5
  • 22
    • 79957448371 scopus 로고    scopus 로고
    • Stable isotope resolved metabolomics of lung cancer in a scid mouse model
    • Fan, T. W., Lane, A. N., Higashi, R. M. & Yan, J. Stable isotope resolved metabolomics of lung cancer in a SCID mouse model. Metabolomics 7, 257-269, doi: 10.1007/s11306-010-0249-0 (2011).
    • (2011) Metabolomics , vol.7 , pp. 257-269
    • Fan, T.W.1    Lane, A.N.2    Higashi, R.M.3    Yan, J.4
  • 23
    • 84945218153 scopus 로고    scopus 로고
    • Diabetes and prediabetes in patients with hepatitis b residing in North America
    • Khalili, M. et al. Diabetes and prediabetes in patients with hepatitis B residing in North America. Hepatology 62, 1364-1374, doi: 10.1002/hep.28110 (2015).
    • (2015) Hepatology , vol.62 , pp. 1364-1374
    • Khalili, M.1
  • 24
    • 84890416015 scopus 로고    scopus 로고
    • Nat8l (n-Acetyltransferase 8-like) accelerates lipid turnover and increases energy expenditure in brown adipocytes
    • Pessentheiner, A. R. et al. NAT8L (N-Acetyltransferase 8-like) accelerates lipid turnover and increases energy expenditure in brown adipocytes. J Biol Chem 288, 36040-36051, doi: 10.1074/jbc.M113.491324 (2013).
    • (2013) J Biol Chem , vol.288 , pp. 36040-36051
    • Pessentheiner, A.R.1
  • 25
    • 84942549525 scopus 로고    scopus 로고
    • Choline deficiency impairs intestinal lipid metabolism in the lactating rat
    • da Silva, R. P. et al. Choline deficiency impairs intestinal lipid metabolism in the lactating rat. J Nutr Biochem 26, 1077-1083, doi: 10.1016/j.jnutbio.2015.04.015 (2015).
    • (2015) J Nutr Biochem , vol.26 , pp. 1077-1083
    • Da Silva, R.P.1
  • 26
    • 84946479403 scopus 로고    scopus 로고
    • Choline supplementation restores substrate balance and alleviates complications of pcyt2 deficiency
    • Schenkel, L. C. et al. Choline supplementation restores substrate balance and alleviates complications of Pcyt2 deficiency. J Nutr Biochem 26, 1221-1234, doi: 10.1016/j.jnutbio.2015.05.014 (2015).
    • (2015) J Nutr Biochem , vol.26 , pp. 1221-1234
    • Schenkel, L.C.1
  • 27
    • 84940184917 scopus 로고    scopus 로고
    • Ablation of xp-v gene causes adipose tissue senescence and metabolic abnormalities
    • Chen, Y. W., Harris, R. A., Hatahet, Z. & Chou, K. M. Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities. Proc Natl Acad Sci U S A 112, E4556-4564, doi: 10.1073/pnas.1506954112 (2015).
    • (2015) Proc Natl Acad Sci U S A , vol.112 , pp. E4556-4564
    • Chen, Y.W.1    Harris, R.A.2    Hatahet, Z.3    Chou, K.M.4
  • 28
    • 77954146394 scopus 로고    scopus 로고
    • Mechanistic and biological aspects of helicase action on damaged DNA
    • Suhasini, A. N. & Brosh, R. M. Jr. Mechanistic and biological aspects of helicase action on damaged DNA. Cell Cycle 9, 2317-2329 (2010).
    • (2010) Cell Cycle , vol.9 , pp. 2317-2329
    • Suhasini, A.N.1    Brosh, R.M.2
  • 29
    • 84907986713 scopus 로고    scopus 로고
    • Protective effect of resveratrol on fluoride induced alteration in protein and nucleic acid metabolism DNA damage and biogenic amines in rat brain
    • Pal, S. & Sarkar, C. Protective effect of resveratrol on fluoride induced alteration in protein and nucleic acid metabolism, DNA damage and biogenic amines in rat brain. Environ Toxicol Pharmacol 38, 684-699, doi: 10.1016/j.etap.2014.07.009 (2014).
    • (2014) Environ Toxicol Pharmacol , vol.38 , pp. 684-699
    • Pal, S.1    Sarkar, C.2
  • 30
    • 70449394392 scopus 로고    scopus 로고
    • Hepatitis b virus x protein (hbx) induces g2/m arrest and apoptosis through sustained activation of cyclin b1-cdk1 kinase
    • Cheng, P. et al. Hepatitis B virus X protein (HBx) induces G2/M arrest and apoptosis through sustained activation of cyclin B1-CDK1 kinase. Oncology Reports 22, doi: 10.3892/or-00000542 (2009).
    • (2009) Oncology Reports , vol.22
    • Cheng, P.1
  • 31
    • 84899682448 scopus 로고    scopus 로고
    • DNA damage repair machinery and HIV escape from innate immune sensing
    • Bregnard, C., Benkirane, M. & Laguette, N. DNA damage repair machinery and HIV escape from innate immune sensing. Front Microbiol 5, 176, doi: 10.3389/fmicb.2014.00176 (2014).
    • (2014) Front Microbiol , vol.5 , pp. 176
    • Bregnard, C.1    Benkirane, M.2    Laguette, N.3
  • 32
    • 84940020820 scopus 로고    scopus 로고
    • Caryocar brasiliense camb protects against genomic and oxidative damage in urethane-induced lung carcinogenesis
    • Colombo, N. B. et al. Caryocar brasiliense camb protects against genomic and oxidative damage in urethane-induced lung carcinogenesis. Braz J Med Biol Res 48, 852-862, doi: 10.1590/1414-431X20154467 (2015).
    • (2015) Braz J Med Biol Res , vol.48 , pp. 852-862
    • Colombo, N.B.1
  • 33
    • 84945480123 scopus 로고    scopus 로고
    • Investigating the effects of in utero benzene exposure on epigenetic modifications in maternal and fetal cd-1 mice
    • Philbrook, N. A. & Winn, L. M. Investigating the effects of in utero benzene exposure on epigenetic modifications in maternal and fetal CD-1 mice. Toxicol Appl Pharmacol 289, 12-19, doi: 10.1016/j.taap.2015.08.019 (2015).
    • (2015) Toxicol Appl Pharmacol , vol.289 , pp. 12-19
    • Philbrook, N.A.1    Winn, L.M.2
  • 34
    • 78649336706 scopus 로고    scopus 로고
    • The DNA damage response: Making it safe to play with knives
    • Ciccia, A. & Elledge, S. J. The DNA Damage Response: Making It Safe to Play with Knives. Molecular Cell 40, 179-204, doi: 10.1016/j. molcel.2010.09.019 (2010).
    • (2010) Molecular Cell , vol.40 , pp. 179-204
    • Ciccia, A.1    Elledge, S.J.2
  • 35
    • 56149087784 scopus 로고    scopus 로고
    • Hepatitis b virus x protein affects s phase progression leading to chromosome segregation defects by binding to damaged DNA binding protein 1
    • Martin-Lluesma, S. et al. Hepatitis B virus X protein affects S phase progression leading to chromosome segregation defects by binding to damaged DNA binding protein 1. Hepatology 48, 1467-1476, doi: 10.1002/hep.22542 (2008).
    • (2008) Hepatology , vol.48 , pp. 1467-1476
    • Martin-Lluesma, S.1
  • 36
    • 84870522970 scopus 로고    scopus 로고
    • Hepatitis b virus x protein stimulates gene expression selectively from extrachromosomal DNA templates
    • van Breugel, P. C. et al. Hepatitis B virus X protein stimulates gene expression selectively from extrachromosomal DNA templates. Hepatology 56, 2116-2124, doi: 10.1002/hep.25928 (2012).
    • (2012) Hepatology , vol.56 , pp. 2116-2124
    • Van Breugel, P.C.1
  • 37
    • 0037064038 scopus 로고    scopus 로고
    • Hepatitis b virus x protein associated with uv-ddb1 induces cell death in the nucleus and is functionally antagonized by uv-ddb2
    • Bontron, S., Lin-Marq, N. & Strubin, M. Hepatitis B virus X protein associated with UV-DDB1 induces cell death in the nucleus and is functionally antagonized by UV-DDB2. J Biol Chem 277, 38847-38854, doi: 10.1074/jbc.M205722200 (2002).
    • (2002) J Biol Chem , vol.277 , pp. 38847-38854
    • Bontron, S.1    Lin-Marq, N.2    Strubin, M.3
  • 38
    • 84925353977 scopus 로고    scopus 로고
    • Technical standards for hepatitis b virus x protein (hbx) research
    • Slagle, B. L. et al. Technical standards for hepatitis B virus X protein (HBx) research. Hepatology 61, 1416-1424, doi: 10.1002/hep.27360 (2015).
    • (2015) Hepatology , vol.61 , pp. 1416-1424
    • Slagle, B.L.1
  • 39
    • 84923322647 scopus 로고    scopus 로고
    • Novel method for the high-throughput processing of slides for the comet assay
    • Karbaschi, M. & Cooke, M. S. Novel method for the high-throughput processing of slides for the comet assay. Sci Rep 4, 7200, doi: 10.1038/srep07200 (2014).
    • (2014) Sci Rep , vol.4 , pp. 7200
    • Karbaschi, M.1    Cooke, M.S.2
  • 40
    • 84930652409 scopus 로고    scopus 로고
    • A new arylbenzofuran derivative functions as an anti-tumour agent by inducing DNA damage and inhibiting parp activity
    • Chen, H. et al. A new arylbenzofuran derivative functions as an anti-tumour agent by inducing DNA damage and inhibiting PARP activity. Sci Rep 5, 10893, doi: 10.1038/srep10893 (2015).
    • (2015) Sci Rep , vol.5 , pp. 10893
    • Chen, H.1
  • 41
    • 84930631534 scopus 로고    scopus 로고
    • The oxidant role of 4-hydroxynonenal in corneal epithelium
    • Chen, L. et al. The oxidant role of 4-hydroxynonenal in corneal epithelium. Sci Rep 5, 10630, doi: 10.1038/srep10630 (2015).
    • (2015) Sci Rep , vol.5 , pp. 10630
    • Chen, L.1
  • 42
    • 84927654227 scopus 로고    scopus 로고
    • Inhibition of immunoproteasome reduces infarction volume and attenuates inflammatory reaction in a rat model of ischemic stroke
    • Chen, X. et al. Inhibition of immunoproteasome reduces infarction volume and attenuates inflammatory reaction in a rat model of ischemic stroke. Cell Death Dis 6, e1626, doi: 10.1038/cddis.2014.586 (2015).
    • (2015) Cell Death Dis , vol.6 , pp. e1626
    • Chen, X.1
  • 43
    • 84929359290 scopus 로고    scopus 로고
    • Reinforcement of stat3 activity reprogrammes human embryonic stem cells to naive-like pluripotency
    • Chen, H. et al. Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency. Nat Commun 6, 7095, doi: 10.1038/ncomms8095 (2015).
    • (2015) Nat Commun , vol.6 , pp. 7095
    • Chen, H.1


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