Disruption of sirtuin 1-mediated control of circadian molecular clock and inflammation in chronic obstructive pulmonary disease

American Journal of Respiratory Cell and Molecular Biology

Volumn 53, Issue 6, 2015, Pages 782-792

  Yao, Hongwei ^a   Sundar, Isaac K ^a   Huang, Yadi ^a   Gerloff, Janice ^a   Sellix, Michael T ^b   Sime, Patricia J ^c   Rahman, Irfan ^a  

^a Lung Biology and Disease Program   (United States)

^b Diabetes and Metabolism   (United States)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Bmal1; Circadian rhythm; Rev erba; Sirt1; Smokers

Indexed keywords

CELL NUCLEUS RECEPTOR; CRYPTOCHROME 1; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; N [2 [3 (1 PIPERAZINYLMETHYL)IMIDAZO[2,1 B]THIAZOL 6 YL]PHENYL] 2 QUINOXALINECARBOXAMIDE; NUCLEAR RECEPTOR NR1D1; PER1 PROTEIN; PER2 PROTEIN; RETINOID RELATED ORPHAN RECEPTOR ALPHA; REV ERB BETA PROTEIN; SIRTUIN 1; TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTION FACTOR CLOCK; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; SIRT1 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LUNG PARENCHYMA; MALE; MEDIATOR RELEASE; MOLECULAR CLOCK; PERIPHERAL BLOOD MONONUCLEAR CELL; SMOKING; SPUTUM; SUPERNATANT; BIOSYNTHESIS; CELL CULTURE; ENZYMOLOGY; IMMUNOLOGY; LUNG; METABOLISM; MIDDLE AGED; MONONUCLEAR CELL; PHYSIOLOGY;

AGED; CELLS, CULTURED; CIRCADIAN CLOCKS; CYTOKINES; FEMALE; HUMANS; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; LUNG; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SIRTUIN 1; SMOKING;

EID: 84963819317     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2014-0474OC     Document Type: Article

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