Differential effects of IGF-1 deficiency during the life span on structural and biomechanical properties in the tibia of aged mice

Age

Volumn 38, Issue 2, 2016, Pages

  Ashpole, Nicole M ^a   Herron, Jacquelyn C ^b   Estep, Patrick N ^c   Logan, Sreemathi ^a   Hodges, Erik L ^a   Yabluchanskiy, Andriy ^a   Humphrey, Mary Beth ^b,d   Sonntag, William E ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

IGF 1; MicroCT; Three point bone bending; Tibia

Indexed keywords

SOMATOMEDIN C;

ADULTHOOD; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE AGE; BONE BOWING; BONE DENSITY; BONE FRACTION; BONE STIFFNESS; BONE STRENGTH; BONE STRUCTURE; CONTROLLED STUDY; CORTICAL BONE; CORTICAL THICKNESS (BONE); DIAPHYSIS; FEMALE; HORMONE DEFICIENCY; LIFESPAN; MALE; MAXIMUM BENDING MOMENT; MAXIMUM FORCE; METAPHYSIS; MICRO-COMPUTED TOMOGRAPHY; MICROENVIRONMENT; MOUSE; MUSCULOSKELETAL SYSTEM PARAMETERS; NONHUMAN; POSTNATAL DEVELOPMENT; SEX DIFFERENCE; TIBIA; TIME; TRABECULAR BONE; TRABECULAR NUMBER; ANIMAL; C57BL MOUSE; DEFICIENCY; DIAGNOSTIC IMAGING; DISEASE MODEL; METABOLISM; TIBIAL FRACTURES;

AGING; ANIMALS; BONE DENSITY; DISEASE MODELS, ANIMAL; FEMALE; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MICE, INBRED C57BL; TIBIA; TIBIAL FRACTURES; X-RAY MICROTOMOGRAPHY;

EID: 84963807900     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-016-9902-5     Document Type: Article

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